Research Topics
Species | Vinuta RauSummaryAffiliation: University of California Country: USA Publications
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Publications
Exposure to a stressor produces a long lasting enhancement of fear learning in ratsVinuta Rau
Department of Anesthesia, University of California, San Francisco, CA 94143, USA
Stress 12:125-33. 2009..The time-course of the enhancement was examined in the next two experiments. These experiments show that SEFL persists for at least 3 months...
Isoflurane suppresses stress-enhanced fear learning in a rodent model of post-traumatic stress disorderVinuta Rau
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143 0464, USA
Anesthesiology 110:487-95. 2009..Subsequent exposure to a single foot shock produces an enhanced fear response. This effect is akin to sensitized reactions shown by some post-traumatic stress disorder patients to cues previously associated with the traumatic event...
Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isofluraneVinuta Rau
Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94143 0464, USA
Anesth Analg 109:1816-22. 2009..GABA(A)-Rs containing the alpha4 subunit are highly concentrated in the hippocampus and thalamus, and when combined with delta subunits they mediate tonic inhibition, which is sensitive to low concentrations of isoflurane...
Isoflurane differentially affects neurogenesis and long-term neurocognitive function in 60-day-old and 7-day-old ratsGreg Stratmann
Department of Anesthesia and Perioperative Care, University of California, San Francisco 94143, USA
Anesthesiology 110:834-48. 2009..Postnatal hippocampal neurogenesis affects hippocampal function into adulthood; therefore, the authors tested the hypothesis that isoflurane affects long-term neurocognitive function via an effect on dentate gyrus neurogenesis...
Gamma-aminobutyric acid type A receptor β3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isofluraneVinuta Rau
Department of Anesthesia, S 455, University of California San Francisco, San Francisco, CA 94143 0464, USA
Anesth Analg 113:500-4. 2011..The end points of amnesia and immobility produced by an inhaled anesthetic have yet to be evaluated in this conditional knockout...
Stress-induced enhancement of fear learning: an animal model of posttraumatic stress disorderVinuta Rau
Department of Psychology, University of California, Los Angeles, 415 Hilgard Ave, Los Angeles, CA 90095 1563, USA
Neurosci Biobehav Rev 29:1207-23. 2005..This model can facilitate the study of neurobiological mechanisms underlying sensitization of responses observed in PTSD...
Delayed environmental enrichment reverses sevoflurane-induced memory impairment in ratsJennifer Shih
Department of Anesthesia, University of California San Francisco, San Francisco, California 94143, USA
Anesthesiology 116:586-602. 2012..We tested the hypothesis that anesthesia-induced cognitive decline in rats is treatable. We also tested if anesthesia-induced cognitive decline is aggravated by tissue injury...
Effect of hypercarbia and isoflurane on brain cell death and neurocognitive dysfunction in 7-day-old ratsGreg Stratmann
Department of Anesthesia and Perioperative Car, University of California, San Francisco, California 94143, USA
Anesthesiology 110:849-61. 2009..The authors therefore tested if cell death caused by various durations of isoflurane at 1 minimum alveolar concentration causes duration-dependent long-term neurocognitive dysfunction...
