Paul H Ratner

Summary

Affiliation: University of Texas
Country: USA

Publications

  1. ncbi request reprint Effectiveness of ciclesonide nasal spray in the treatment of seasonal allergic rhinitis
    Paul H Ratner
    Sylvana Research, San Antonio, Texas 78229, USA
    Ann Allergy Asthma Immunol 97:657-63. 2006
  2. ncbi request reprint Efficacy and safety of ciclesonide nasal spray for the treatment of seasonal allergic rhinitis
    Paul H Ratner
    Sylvana Research, Department of Pediatrics, University of Texas Health Science Center, San Antonio, TX 78229, USA
    J Allergy Clin Immunol 118:1142-8. 2006
  3. ncbi request reprint Intranasal corticosteroids in the treatment of allergic rhinitis
    Paul H Ratner
    Sylvana Research Associates, 7711 Louis Pasteur Drive, Suite 407, San Antonio, TX 78229, USA
    Allergy Asthma Proc 28:S25-32. 2007
  4. ncbi request reprint Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis to mountain cedar
    Paul H Ratner
    Sylvana Research, San Antonio, Texas 78229, USA
    Ann Allergy Asthma Immunol 95:474-9. 2005
  5. ncbi request reprint Efficacy and safety of ebastine 20 mg compared to loratadine 10 mg once daily in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled study
    P Ratner
    Sylvana Research, San Antonio, TX 78229, USA
    Int Arch Allergy Immunol 133:371-9. 2004
  6. ncbi request reprint Efficacy of ebastine in the control of nasal congestion associated with allergic rhinitis
    P Ratner
    Sylvana Research Associates, San Antonio, Texas, USA
    Methods Find Exp Clin Pharmacol 25:111-5. 2003
  7. doi request reprint Double-blind, placebo-controlled study of azelastine and fluticasone in a single nasal spray delivery device
    Frank C Hampel
    Central Texas Health Research, New Braunfels, Texas, USA
    Ann Allergy Asthma Immunol 105:168-73. 2010
  8. ncbi request reprint Improved quality of life among seasonal allergic rhinitis patients treated with olopatadine HCl nasal spray 0.4% and olopatadine HCl nasal spray 0.6% compared with vehicle placebo
    Frank C Hampel
    Central Texas Health Research, New Braunfels and San Antonio, Texas, 78130, USA
    Allergy Asthma Proc 27:202-7. 2006
  9. ncbi request reprint Optimal dose selection of fluticasone furoate nasal spray for the treatment of seasonal allergic rhinitis in adults and adolescents
    Bruce G Martin
    Southwest Allergy and Asthma Research, San Antonio, Texas 78229, USA
    Allergy Asthma Proc 28:216-25. 2007
  10. doi request reprint Once-daily treatment with beclomethasone dipropionate nasal aerosol does not affect hypothalamic-pituitary-adrenal axis function
    Paul H Ratner
    Sylvana Research Associates, San Antonio, Texas 78229, USA
    Ann Allergy Asthma Immunol 109:336-41. 2012

Detail Information

Publications21

  1. ncbi request reprint Effectiveness of ciclesonide nasal spray in the treatment of seasonal allergic rhinitis
    Paul H Ratner
    Sylvana Research, San Antonio, Texas 78229, USA
    Ann Allergy Asthma Immunol 97:657-63. 2006
    ..In vitro studies in human nasal epithelial cells and bronchial epithelial cells have demonstrated a long duration of anti-inflammatory activity of des-CIC...
  2. ncbi request reprint Efficacy and safety of ciclesonide nasal spray for the treatment of seasonal allergic rhinitis
    Paul H Ratner
    Sylvana Research, Department of Pediatrics, University of Texas Health Science Center, San Antonio, TX 78229, USA
    J Allergy Clin Immunol 118:1142-8. 2006
    ..Ciclesonide nasal spray is a corticosteroid being developed as a hypotonic formulation for AR...
  3. ncbi request reprint Intranasal corticosteroids in the treatment of allergic rhinitis
    Paul H Ratner
    Sylvana Research Associates, 7711 Louis Pasteur Drive, Suite 407, San Antonio, TX 78229, USA
    Allergy Asthma Proc 28:S25-32. 2007
    ..Therefore, intranasal ciclesonide appears to provide an additional treatment option for patients with AR...
  4. ncbi request reprint Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis to mountain cedar
    Paul H Ratner
    Sylvana Research, San Antonio, Texas 78229, USA
    Ann Allergy Asthma Immunol 95:474-9. 2005
    ..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR) to mountain cedar...
  5. ncbi request reprint Efficacy and safety of ebastine 20 mg compared to loratadine 10 mg once daily in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled study
    P Ratner
    Sylvana Research, San Antonio, TX 78229, USA
    Int Arch Allergy Immunol 133:371-9. 2004
    ..Few randomized studies have compared loratadine to ebastine in the symptomatic treatment of seasonal allergic rhinitis (SAR) patients...
  6. ncbi request reprint Efficacy of ebastine in the control of nasal congestion associated with allergic rhinitis
    P Ratner
    Sylvana Research Associates, San Antonio, Texas, USA
    Methods Find Exp Clin Pharmacol 25:111-5. 2003
    ..This symptomatic effect of ebastine may be accounted for by its ability to reduce inflammatory markers, as shown in preclinical studies, in addition to its primary effect of antagonizing histamine H1 receptors...
  7. doi request reprint Double-blind, placebo-controlled study of azelastine and fluticasone in a single nasal spray delivery device
    Frank C Hampel
    Central Texas Health Research, New Braunfels, Texas, USA
    Ann Allergy Asthma Immunol 105:168-73. 2010
    ....
  8. ncbi request reprint Improved quality of life among seasonal allergic rhinitis patients treated with olopatadine HCl nasal spray 0.4% and olopatadine HCl nasal spray 0.6% compared with vehicle placebo
    Frank C Hampel
    Central Texas Health Research, New Braunfels and San Antonio, Texas, 78130, USA
    Allergy Asthma Proc 27:202-7. 2006
    ..Olopatadine nasal spray is an effective antiallergy medication that significantly improves the QoL of patients suffering from SAR...
  9. ncbi request reprint Optimal dose selection of fluticasone furoate nasal spray for the treatment of seasonal allergic rhinitis in adults and adolescents
    Bruce G Martin
    Southwest Allergy and Asthma Research, San Antonio, Texas 78229, USA
    Allergy Asthma Proc 28:216-25. 2007
    ..The 110-microg dose was chosen for phase III development because it achieved statistically significant and clinically meaningful results for all efficacy end points and provided the optimal risk-benefit ratio...
  10. doi request reprint Once-daily treatment with beclomethasone dipropionate nasal aerosol does not affect hypothalamic-pituitary-adrenal axis function
    Paul H Ratner
    Sylvana Research Associates, San Antonio, Texas 78229, USA
    Ann Allergy Asthma Immunol 109:336-41. 2012
    ..Intranasal corticosteroids are effective in controlling allergic rhinitis (AR) symptoms; however, chronic administration of corticosteroids may suppress hypothalamic-pituitary-adrenal (HPA)-axis function...
  11. ncbi request reprint Fluticasone propionate aqueous nasal spray provided significantly greater improvement in daytime and nighttime nasal symptoms of seasonal allergic rhinitis compared with montelukast
    Paul H Ratner
    Sylvana Research Associates, San Antonio, Texas, USA
    Ann Allergy Asthma Immunol 90:536-42. 2003
    ..Montelukast is a leukotriene receptor antagonist recently approved for the treatment of seasonal allergic rhinitis (SAR)...
  12. doi request reprint Safety and efficacy of olopatadine hydrochloride nasal spray 0.6% in pediatric subjects with allergic rhinitis
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
    Allergy Asthma Proc 30:612-23. 2009
    ..In subjects 6 to <12 years of age, OLO was superior to vehicle in the treatment of SAR. In subjects 2 to <12 years of age, OLO had an overall low rate of AEs and low systemic exposure...
  13. doi request reprint Mometasone furoate nasal spray is safe and effective for 1-year treatment of children with perennial allergic rhinitis
    Paul H Ratner
    Sylvana Research Associates, San Antonio, TX 78229, USA
    Int J Pediatr Otorhinolaryngol 73:651-7. 2009
    ..In this study, the long-term safety and efficacy of mometasone furoate nasal spray (MFNS) were assessed in children with PAR...
  14. doi request reprint Combination therapy with azelastine hydrochloride nasal spray and fluticasone propionate nasal spray in the treatment of patients with seasonal allergic rhinitis
    Paul H Ratner
    Sylvana Research, San Antonio, Texas, USA
    Ann Allergy Asthma Immunol 100:74-81. 2008
    ....
  15. doi request reprint The mountain cedar model in clinical trials of seasonal allergic rhinoconjunctivitis
    Charles P Andrews
    Diagnostics Research Group, San Antonio, Texas 78229, USA
    Ann Allergy Asthma Immunol 111:9-13. 2013
    ..Clinical trials of seasonal allergic rhinoconjunctivitis use the mountain cedar (Juniperus ashei) season as the predominate model...
  16. doi request reprint A study of the efficacy and safety of ciclesonide hydrofluoroalkane nasal aerosol in patients with seasonal allergic rhinitis from mountain cedar pollen
    Paul H Ratner
    Sylvana Research Associates, San Antonio, Texas 78229, USA
    Allergy Asthma Proc 33:27-35. 2012
    ..Both active treatments were well tolerated. Clinical trial registry URL and registration number: www.clinicaltrials.gov/ct2/show/NCT01010971...
  17. doi request reprint Pharmacokinetic profile of beclomethasone dipropionate hydrofluoroalkane after intranasal administration versus oral inhalation in healthy subjects: results of a single-dose, randomized, open-label, 3-period crossover study
    Paul H Ratner
    Sylvana Research Associates, San Antonio, TX 78229, USA
    Clin Ther 34:1422-31. 2012
    ..Recently, a hydrofluoroalkane (HFA)-propelled nasal aerosol formulation of BDP was developed to treat allergic rhinitis. However, the pharmacokinetic profile of BDP HFA nasal aerosol has not been previously investigated...
  18. ncbi request reprint Relief of sinus pain and pressure with fluticasone propionate aqueous nasal spray: a placebo-controlled trial in patients with allergic rhinitis
    Paul H Ratner
    HealthQuest Therapy and Research Institute, Austin, Texas, USA
    Allergy Asthma Proc 23:259-63. 2002
    ..Our data indicate that symptoms of sinus pain and pressure and nasal congestion can be significantly reduced in patients with allergic rhinitis when treated with fluticasone propionate aqueous nasal spray, 200 mcg once daily...
  19. ncbi request reprint Use of intranasal cromolyn sodium for allergic rhinitis
    Paul H Ratner
    Sylvana Research Associates and Department of Pediatrics, University of Texas Health Science Center, San Antonio, USA
    Mayo Clin Proc 77:350-4. 2002
    ..Intranasal cromolyn has an excellent safety record, is available as an over-the-counter medication, and has been proved to be efficacious in patients with allergic rhinitis...
  20. ncbi request reprint Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 95:600-6. 2005
    ..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR)...
  21. ncbi request reprint Validation of the nighttime symptoms score as a clinically relevant measure of allergic rhinitis
    Nancy C Santanello
    Merck Research Laboratories, Rahway, New Jersey, USA
    Allergy Asthma Proc 27:231-9. 2006
    ..Sleep quality questions measure aspects of SAR that are not captured by daytime SAR symptoms. The results show that the NSS is a valid and relevant clinical measure of the impact of nighttime sleep disturbance on AR patients...