DENNIS D contact RASMUSSEN

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Effects of chronic nicotine treatment and withdrawal on hypothalamic proopiomelanocortin gene expression and neuroendocrine regulation
    D D Rasmussen
    Mental Health Service, VA Puget Sound Health Care System, Seattle, WA, USA
    Psychoneuroendocrinology 23:245-59. 1998
  2. pmc Acoustic startle amplitude predicts vulnerability to develop post-traumatic stress hyper-responsivity and associated plasma corticosterone changes in rats
    Dennis D Rasmussen
    VA Puget Sound Health Care System, Mental Illness Research, Education and Clinical Center, Seattle, WA 98108, USA
    Psychoneuroendocrinology 33:282-91. 2008
  3. pmc Chronic daily ethanol and withdrawal: 6. Effects on rat sympathoadrenal activity during "abstinence"
    Dennis D Rasmussen
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center, University of Washington, Seattle, WA 98108, USA
    Alcohol 38:173-7. 2006
  4. ncbi request reprint Chronic daily ethanol and withdrawal: 5. Diurnal effects on plasma thyroid hormone levels
    Dennis D Rasmussen
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center and the Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA
    Endocrine 22:329-34. 2003
  5. ncbi request reprint Chronic daily ethanol and withdrawal: 4. Long-term changes in plasma testosterone regulation, but no effect on GnRH gene expression or plasma LH concentrations
    Dennis D Rasmussen
    VA Puget Sound Health Care System, S 116 Mental Illness Research, Education and Clinical Center, 1660 S Columbian Way, Seattle, WA, USA
    Endocrine 22:143-50. 2003
  6. ncbi request reprint Melatonin effect on rat body weight regulation in response to high-fat diet at middle age
    Stephaney S Puchalski
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center MIRECC and Department of Psychiatry, University of Washington, Seattle, WA 98108, USA
    Endocrine 21:163-7. 2003
  7. ncbi request reprint Chronic daily ethanol and withdrawal: 3. Forebrain pro-opiomelanocortin gene expression and implications for dependence, relapse, and deprivation effect
    Dennis D Rasmussen
    Veterans Affairs Puget Sound Health Care System Mental Illness Research, Education and Clinical Center, Seattle, Washington, USA
    Alcohol Clin Exp Res 26:535-46. 2002
  8. ncbi request reprint Chronic daily ethanol and withdrawal: 2. Behavioral changes during prolonged abstinence
    D D Rasmussen
    Veteran s Assistance Puget Sound Health Care System Mental Illness Research, Education and Clinical Center, Departments of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA
    Alcohol Clin Exp Res 25:999-1005. 2001
  9. ncbi request reprint Daily melatonin administration at middle age suppresses male rat visceral fat, plasma leptin, and plasma insulin to youthful levels
    D D Rasmussen
    VA Puget Sound Health Care System, and Department of Medicine, University of Washington, Seattle 98195, USA
    Endocrinology 140:1009-12. 1999
  10. ncbi request reprint Aging-dependent changes in the effect of daily melatonin supplementation on rat metabolic and behavioral responses
    D D Rasmussen
    VA Puget Sound Health Care System, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195, USA
    J Pineal Res 31:89-94. 2001

Research Grants

  1. Neuroendocrine Therapy of Alcohol Abuse
    DENNIS RASMUSSEN; Fiscal Year: 2006
  2. ALCOHOL EFFECTS ON OPIOMELANOCORTINERGIC REGULATION
    DENNIS RASMUSSEN; Fiscal Year: 2009
  3. ALCOHOL EFFECTS ON OPIOMELANOCORTINERGIC REGULATION
    DENNIS RASMUSSEN; Fiscal Year: 2007
  4. Metabolic Changes During Aging: A Role for Melatonin
    DENNIS RASMUSSEN; Fiscal Year: 2003
  5. ALCOHOL EFFECTS ON OPIOMELANOCORTINERGIC REGULATION
    DENNIS RASMUSSEN; Fiscal Year: 2001
  6. Noradrenergic Agents As Potential New Pharmacotherapies for Alcohol Drinking
    DENNIS D contact RASMUSSEN; Fiscal Year: 2010

Detail Information

Publications17

  1. ncbi request reprint Effects of chronic nicotine treatment and withdrawal on hypothalamic proopiomelanocortin gene expression and neuroendocrine regulation
    D D Rasmussen
    Mental Health Service, VA Puget Sound Health Care System, Seattle, WA, USA
    Psychoneuroendocrinology 23:245-59. 1998
    ....
  2. pmc Acoustic startle amplitude predicts vulnerability to develop post-traumatic stress hyper-responsivity and associated plasma corticosterone changes in rats
    Dennis D Rasmussen
    VA Puget Sound Health Care System, Mental Illness Research, Education and Clinical Center, Seattle, WA 98108, USA
    Psychoneuroendocrinology 33:282-91. 2008
    ..These results suggest that initial pre-stress acoustic startle response can identify subgroups of rats which are predisposed to, or resistant to, developing a PTSD-like syndrome following subsequent trauma...
  3. pmc Chronic daily ethanol and withdrawal: 6. Effects on rat sympathoadrenal activity during "abstinence"
    Dennis D Rasmussen
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center, University of Washington, Seattle, WA 98108, USA
    Alcohol 38:173-7. 2006
    ..These results suggest that daily ethanol consumption can induce persistent increases in sympathoadrenal activation during subsequent "abstinence," which are relatively refractory to further stimulation...
  4. ncbi request reprint Chronic daily ethanol and withdrawal: 5. Diurnal effects on plasma thyroid hormone levels
    Dennis D Rasmussen
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center and the Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA
    Endocrine 22:329-34. 2003
    ..Further investigations with this rat model of daily ethanol consumption and daily withdrawal will help resolve interactions and roles of the HPT axis in alcohol abuse...
  5. ncbi request reprint Chronic daily ethanol and withdrawal: 4. Long-term changes in plasma testosterone regulation, but no effect on GnRH gene expression or plasma LH concentrations
    Dennis D Rasmussen
    VA Puget Sound Health Care System, S 116 Mental Illness Research, Education and Clinical Center, 1660 S Columbian Way, Seattle, WA, USA
    Endocrine 22:143-50. 2003
    ....
  6. ncbi request reprint Melatonin effect on rat body weight regulation in response to high-fat diet at middle age
    Stephaney S Puchalski
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center MIRECC and Department of Psychiatry, University of Washington, Seattle, WA 98108, USA
    Endocrine 21:163-7. 2003
    ..Thus, melatonin decreased weight gain in response to high-fat diet, decreased plasma leptin levels within 3 wk-before decreasing plasma insulin-and exerted these metabolic effects independent of total food consumption...
  7. ncbi request reprint Chronic daily ethanol and withdrawal: 3. Forebrain pro-opiomelanocortin gene expression and implications for dependence, relapse, and deprivation effect
    Dennis D Rasmussen
    Veterans Affairs Puget Sound Health Care System Mental Illness Research, Education and Clinical Center, Seattle, Washington, USA
    Alcohol Clin Exp Res 26:535-46. 2002
    ....
  8. ncbi request reprint Chronic daily ethanol and withdrawal: 2. Behavioral changes during prolonged abstinence
    D D Rasmussen
    Veteran s Assistance Puget Sound Health Care System Mental Illness Research, Education and Clinical Center, Departments of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA
    Alcohol Clin Exp Res 25:999-1005. 2001
    ..Accordingly, we have investigated persistent behavioral effects of previous repetitive daily ethanol consumption and withdrawal...
  9. ncbi request reprint Daily melatonin administration at middle age suppresses male rat visceral fat, plasma leptin, and plasma insulin to youthful levels
    D D Rasmussen
    VA Puget Sound Health Care System, and Department of Medicine, University of Washington, Seattle 98195, USA
    Endocrinology 140:1009-12. 1999
    ....
  10. ncbi request reprint Aging-dependent changes in the effect of daily melatonin supplementation on rat metabolic and behavioral responses
    D D Rasmussen
    VA Puget Sound Health Care System, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195, USA
    J Pineal Res 31:89-94. 2001
    ....
  11. ncbi request reprint Chronic daily ethanol and withdrawal: 1. Long-term changes in the hypothalamo-pituitary-adrenal axis
    D D Rasmussen
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center, University of Washington, Seattle, USA
    Alcohol Clin Exp Res 24:1836-49. 2000
    ..Consequently, we investigated whether chronic daily ethanol consumption and withdrawal by male Sprague Dawley rats would induce persistent HPA changes consistent with those demonstrated in abstinent alcoholics...
  12. ncbi request reprint Reduced gene expression for dopamine biosynthesis and transport in midbrain neurons of adult male rats exposed prenatally to ethanol
    P Szot
    Geriatric Research, Education and Clinical Center, Puget Sound Health Care System, and the Department of Psychiatry, University of Washington, Seattle 98108, USA
    Alcohol Clin Exp Res 23:1643-9. 1999
    ..Prenatal ethanol exposure affects brain dopaminergic neuronal systems, and many of these alterations are permanent...
  13. ncbi request reprint Suppression of hypothalamic pro-opiomelanocortin (POMC) gene expression by daily melatonin supplementation in aging rats
    Dennis D Rasmussen
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center DDR, Seattle, Washington 98108, USA
    J Pineal Res 34:127-33. 2003
    ..These POMC responses were apparently not dependent on gonadal steroid responses and did not become refractory to melatonin treatment maintained until old age...
  14. ncbi request reprint Alcoholism, craving, and hormones: the role of leptin, ghrelin, prolactin, and the pro-opiomelanocortin system in modulating ethanol intake
    Friedrich Martin Wurst
    Christian Doppler Clinic, Department of Psychiatry and Psychotherapy II Addiction Medicine, Paracelsus Medical University, Salzburg, Austria
    Alcohol Clin Exp Res 31:1963-7. 2007
    ..The goal of this mini-review is to discuss the results of some recent investigations of the potential interactions of these systems with acute and chronic alcohol responses...
  15. pmc alpha1-noradrenergic receptor antagonism blocks dependence-induced increases in responding for ethanol
    Brendan M Walker
    Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA
    Alcohol 42:91-7. 2008
    ..None of the doses tested reliably affected concurrent water self-administration. These results suggest the involvement of the noradrenergic system in the excessive alcohol drinking seen during acute withdrawal in ethanol-dependent rats...
  16. ncbi request reprint Melatonin effects on metabolism independent of gonad function
    Stephaney S Puchalski
    VA Puget Sound Health Care System Mental Illness Research, Education and Clinical Center MIRECC and Department of Psychiatry, University of Washington, Seattle, Washington 98108, USA
    Endocrine 21:169-73. 2003
    ..These results demonstrate that suppression of body weight, visceral adiposity, and plasma leptin levels by daily melatonin administration to middle-aged rats was independent of gonadal function...
  17. ncbi request reprint Olanzapine-induced weight gain and increased visceral adiposity is blocked by melatonin replacement therapy in rats
    Murray A Raskind
    VA Puget Sound Health Care System, Mental Illness Research, Education and Clinical Center, Seattle, WA 98108, USA
    Neuropsychopharmacology 32:284-8. 2007
    ....

Research Grants16

  1. Neuroendocrine Therapy of Alcohol Abuse
    DENNIS RASMUSSEN; Fiscal Year: 2006
    ....
  2. ALCOHOL EFFECTS ON OPIOMELANOCORTINERGIC REGULATION
    DENNIS RASMUSSEN; Fiscal Year: 2009
    ....
  3. ALCOHOL EFFECTS ON OPIOMELANOCORTINERGIC REGULATION
    DENNIS RASMUSSEN; Fiscal Year: 2007
    ....
  4. Metabolic Changes During Aging: A Role for Melatonin
    DENNIS RASMUSSEN; Fiscal Year: 2003
    ....
  5. ALCOHOL EFFECTS ON OPIOMELANOCORTINERGIC REGULATION
    DENNIS RASMUSSEN; Fiscal Year: 2001
    ....
  6. Noradrenergic Agents As Potential New Pharmacotherapies for Alcohol Drinking
    DENNIS D contact RASMUSSEN; Fiscal Year: 2010
    ..These studies will also provide the basis for development of additional related medications and paradigms for successfully treating alcohol abuse. ..