David A Rasko

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc The first decade of microbial genomics: what have we learned and where are we going next?
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Genome Biol 6:341. 2005
  2. pmc Complete sequence analysis of novel plasmids from emetic and periodontal Bacillus cereus isolates reveals a common evolutionary history among the B. cereus-group plasmids, including Bacillus anthracis pXO1
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
    J Bacteriol 189:52-64. 2007
  3. pmc Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species
    Karen E Nelson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Nucleic Acids Res 32:2386-95. 2004
  4. pmc Major structural differences and novel potential virulence mechanisms from the genomes of multiple campylobacter species
    Derrick E Fouts
    The Institute for Genomic Research, Rockville, Maryland, United States of America
    PLoS Biol 3:e15. 2005
  5. pmc The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Nucleic Acids Res 32:977-88. 2004
  6. pmc Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens
    Garry S A Myers
    The Institute for Genomic Research, Rockville, Maryland 20850, USA
    Genome Res 16:1031-40. 2006
  7. pmc The complete genome sequence of Bacillus anthracis Ames "Ancestor"
    Jacques Ravel
    The Institute for Genomic Research, Rockville, Maryland 20850, USA
    J Bacteriol 191:445-6. 2009
  8. ncbi request reprint Genomics of the Bacillus cereus group of organisms
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    FEMS Microbiol Rev 29:303-29. 2005
  9. pmc Sequencing Bacillus anthracis typing phages gamma and cherry reveals a common ancestry
    Derrick E Fouts
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
    J Bacteriol 188:3402-8. 2006
  10. pmc Visualization of comparative genomic analyses by BLAST score ratio
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    BMC Bioinformatics 6:2. 2005

Collaborators

Detail Information

Publications23

  1. pmc The first decade of microbial genomics: what have we learned and where are we going next?
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Genome Biol 6:341. 2005
  2. pmc Complete sequence analysis of novel plasmids from emetic and periodontal Bacillus cereus isolates reveals a common evolutionary history among the B. cereus-group plasmids, including Bacillus anthracis pXO1
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
    J Bacteriol 189:52-64. 2007
    ..This study demonstrates that the pXO1-like plasmids may define pathogenic B. cereus isolates in the same way that pXO1 and pXO2 define the B. anthracis species...
  3. pmc Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species
    Karen E Nelson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Nucleic Acids Res 32:2386-95. 2004
    ..Whole genome comparative analyses revealed that the L.monocytogenes genomes are essentially syntenic, with the majority of genomic differences consisting of phage insertions, transposable elements and SNPs...
  4. pmc Major structural differences and novel potential virulence mechanisms from the genomes of multiple campylobacter species
    Derrick E Fouts
    The Institute for Genomic Research, Rockville, Maryland, United States of America
    PLoS Biol 3:e15. 2005
    ....
  5. pmc The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Nucleic Acids Res 32:977-88. 2004
    ..The chromosomal similarity of B.cereus ATCC 10987 to B.anthracis Ames, as well as the fact that it contains a large pXO1-like plasmid, may make it a possible model for studying B.anthracis plasmid biology and regulatory cross-talk...
  6. pmc Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens
    Garry S A Myers
    The Institute for Genomic Research, Rockville, Maryland 20850, USA
    Genome Res 16:1031-40. 2006
    ....
  7. pmc The complete genome sequence of Bacillus anthracis Ames "Ancestor"
    Jacques Ravel
    The Institute for Genomic Research, Rockville, Maryland 20850, USA
    J Bacteriol 191:445-6. 2009
    ..This study describes the complete genome sequence of that original isolate, derived from a sample kept in cold storage since 1981...
  8. ncbi request reprint Genomics of the Bacillus cereus group of organisms
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    FEMS Microbiol Rev 29:303-29. 2005
    ..Genomic data have spurred functional studies that combined microarrays and proteomics. Recent advances are reviewed in this article and highlight the advantages of genomic approaches to the study of this important group of bacteria...
  9. pmc Sequencing Bacillus anthracis typing phages gamma and cherry reveals a common ancestry
    Derrick E Fouts
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
    J Bacteriol 188:3402-8. 2006
    ..The genomes of these two phages were identical except at three variable loci, which showed heterogeneity within individual lysates and among Cherry, Wbeta, Fah, and four Gamma bacteriophage sequences...
  10. pmc Visualization of comparative genomic analyses by BLAST score ratio
    David A Rasko
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    BMC Bioinformatics 6:2. 2005
    ..This massive influx of data provides the opportunity to obtain biological insights through comparative genomics. However few tools are available for this scale of comparative analysis...
  11. pmc Investigating the genome diversity of B. cereus and evolutionary aspects of B. anthracis emergence
    Leka Papazisi
    Pathogen Functional Genomics Resource Center PFGRC, The J Craig Venter Institute JCVI, Rockville, MD 20850, USA
    Genomics 98:26-39. 2011
    ..anthracis, the evolution of this species and its close relatives was associated with an overall shift in the fraction of genes devoted to energy metabolism, cellular processes, transport, as well as virulence...
  12. ncbi request reprint Bugs N the 'hood
    David A Rasko
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20580, USA
    Trends Microbiol 12:155-6. 2004
  13. pmc Formation and composition of the Bacillus anthracis endospore
    Hongbin Liu
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA
    J Bacteriol 186:164-78. 2004
    ..This study also highlights the complementary nature of genomic and proteomic analyses and the benefits of combining these approaches in a single study...
  14. pmc Identification of anthrax toxin genes in a Bacillus cereus associated with an illness resembling inhalation anthrax
    Alex R Hoffmaster
    Epidemiologic Investigations Laboratory, Meningitis and Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G34, Atlanta, GA 30333, USA
    Proc Natl Acad Sci U S A 101:8449-54. 2004
    ..In this study, we combined a public health approach with genome analysis to provide insight into the correlation of phenotypic characteristics and their genetic basis...
  15. pmc The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates
    David A Rasko
    Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, 20 Penn Street, Baltimore, MD 21201, USA
    J Bacteriol 190:6881-93. 2008
    ..This comparative study of the species E. coli, while descriptive, should provide the basis for future functional work on this important group of pathogens...
  16. pmc The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever
    Mark Eppinger
    J Craig Venter Institute The Institute for Genomic Research, Microbial Genomics, Rockville, Maryland, United States of America
    PLoS Genet 3:e142. 2007
    ....
  17. pmc Global effects of the cell-to-cell signaling molecules autoinducer-2, autoinducer-3, and epinephrine in a luxS mutant of enterohemorrhagic Escherichia coli
    Melissa M Kendall
    University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9048, USA
    Infect Immun 75:4875-84. 2007
    ..This study began to examine the global signaling networks in EHEC and revealed expression profiles that are signal and pathogen specific...
  18. pmc Metabolic analysis of Moraxella catarrhalis and the effect of selected in vitro growth conditions on global gene expression
    Wei Wang
    Department of Microbiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9048, USA
    Infect Immun 75:4959-71. 2007
    ..These results indicate that growth of M. catarrhalis in a biofilm results in increased expression of gene products which can function not only in energy generation but also in resisting certain elements of the innate immune response...
  19. pmc QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli
    Regan M Russell
    University of Texas Southwestern Medical Center, Department of Microbiology, Dallas, TX 75390 9048, USA
    J Bacteriol 189:5387-92. 2007
    ..This work demonstrates that GrlR/GrlA activate LEE2 transcription in a Ler-independent fashion, whereas transcription of grlRA is activated by QseA in both Ler-dependent and -independent manners...
  20. pmc Development of novel plasmid vectors and a promoter trap system in Francisella tularensis compatible with the pFLN10 based plasmids
    David A Rasko
    University of Texas Southwestern Medical Center at Dallas, Department of Microbiology, 6000 Harry Hines Blvd, Room NA6 138, Dallas, TX 75235 9048, USA
    Plasmid 58:159-66. 2007
    ..tularensis genetics. Our promoter trap can identify promoters that are activated during intracellular growth and survival. These new vectors provide additional tools for the genetic manipulation of F. tularensis...
  21. pmc Defining genomic islands and uropathogen-specific genes in uropathogenic Escherichia coli
    Amanda L Lloyd
    Department of Microbiology and Immunology, University of Michigan Medical School, 5641 Medical Science Bldg II, 1150 West Medical Center Dr, Ann Arbor, MI 48109 0620, USA
    J Bacteriol 189:3532-46. 2007
    ..The large number of hypothetical genes in the CFT073 genome, especially those shown to be UPEC specific, strongly suggests that many urovirulence factors remain uncharacterized...
  22. ncbi request reprint Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment
    Mary Ann Moran
    Department of Marine Sciences, University of Georgia, Athens, Georgia 30602, USA
    Nature 432:910-3. 2004
    ..This bacterium has a physiology distinct from that of marine oligotrophs, adding a new strategy to the recognized repertoire for coping with a nutrient-poor ocean...
  23. pmc Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella
    Eric W Schmidt
    Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA
    Proc Natl Acad Sci U S A 102:7315-20. 2005
    ..In addition, a related cluster was identified in Trichodesmium erythraeum IMS101, an important bloom-forming cyanobacterium...