Research Topics
| A RapkinSummaryAffiliation: University of California Country: USA Publications
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Publications
Pathophysiology of premenstrual syndrome and premenstrual dysphoric disorderAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
Menopause Int 18:52-9. 2012..Brain imaging studies have begun to shed light on the complex brain circuitry underlying affect and behaviour and may help to explicate the intricate neurophysiological foundation of the syndrome...
Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal womenMelinda L Morgan
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095 1740, USA
Arch Womens Ment Health 13:91-8. 2010..Estradiol exposure did not alter ALLO, DHEA, or THDOC, implying these NAS are unlikely to play a role in any mood changes in post menopausal women given estrogen therapy...
Vasomotor symptoms in menopause: physiologic condition and central nervous system approaches to treatmentAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1740, USA
Am J Obstet Gynecol 196:97-106. 2007..Most notable among these are vasomotor symptoms (hot flashes and night sweats) and mood and sleep disturbances...- Drospirenone: a novel progestinAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1740, USA
Expert Opin Pharmacother 8:989-99. 2007.... - The pharmacologic management of premenstrual dysphoric disorderAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, California 90095 1740, USA
Expert Opin Pharmacother 9:429-45. 2008.... - Drospirenone/ethinyl estradiolAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California, USA
Drugs Today (Barc) 44:133-45. 2008..It has received U.S. Food and Drug Administration (FDA) indications not only for the prevention of pregnancy but also for PMDD and for moderate acne vulgaris in women who choose oral contraception for birth control (4, 5)... - Premenstrual syndrome and premenstrual dysphoric disorder in adolescentsAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1740, USA
Curr Opin Obstet Gynecol 20:455-63. 2008..To review the current knowledge about the prevalence, diagnosis, and management of premenstrual syndromes in adolescents... - YAZ in the treatment of premenstrual dysphoric disorderAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Center for Health Sciences, 10833 Le Conte Avenue, Los Angeles, CA 90095 1740, USA
J Reprod Med 53:729-41. 2008.... - Premenstrual syndrome and premenstrual dysphoric disorder: quality of life and burden of illnessAndrea J Rapkin
Professor of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Expert Rev Pharmacoecon Outcomes Res 9:157-70. 2009..This review will focus on the epidemiology, diagnosis, treatment outcomes, quality of life and burden of illness for premenstrual disorders... - Ethinyl estradiol/drospirenone for the treatment of the emotional and physical symptoms of premenstrual dysphoric disorderAndrea J Rapkin
David Geffen School of Medicine at UCLA, Department of Obstetrics and Gynecology, 10833 Le Conte Avenue, Los Angeles, CA 90095 1740, USA
Womens Health (Lond Engl) 3:395-408. 2007.... - Neuroimaging evidence of cerebellar involvement in premenstrual dysphoric disorderAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California 90095 1740, USA
Biol Psychiatry 69:374-80. 2011..Despite a prevalence of up to 8% in women of reproductive age, few studies have investigated the brain mechanisms that underlie this disorder... - Peritoneal fluid interleukin-6 in women with chronic pelvic painA Rapkin
Department of Obstetrics and Gynecology, UCLA School of Medicine, Los Angeles, California 90095 1740, USA
Fertil Steril 74:325-8. 2000..To determine the relationship between peritoneal fluid concentrations of interleukin-6 (IL-6) and chronic pelvic pain symptomatology in women with adhesions, endometriosis, or no obvious intraperitoneal pathology... - New treatment approaches for premenstrual disordersAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1740, USA
Am J Manag Care 11:S480-91. 2005..New pharmacologic research is promising and is discussed along with the need to provide empathetic counseling for patients to determine the approach that will work best for each individual... - The clinical nature and formal diagnosis of premenstrual, postpartum, and perimenopausal affective disordersAndrea J Rapkin
Department of Obstetrics and Gynecology, University of California, Los Angeles Medical Center, Box 951740, 27 139 CHS, Los Angeles, CA 90095, USA
Curr Psychiatry Rep 4:419-28. 2002..All of these disorders share risk factors, and have etiologic features in common, such as exposure to the rise and fall of ovarian sex steroids. The following is a review of these syndromes and their etiology, diagnosis, and treatment... - A review of treatment of premenstrual syndrome and premenstrual dysphoric disorderAndrea Rapkin
UCLA School of Medicine, Department of Obstetrics and Gynecology, Center for the Health Sciences, Los Angeles, CA 90095 1740, USA
Psychoneuroendocrinology 28:39-53. 2003..The studies are in progress, however, preliminary evidence suggests that the drospirenone-containing pill called Yasmin may be effective the treatment of PMDD... - Relationships among self-rated tanner staging, hormones, and psychosocial factors in healthy female adolescentsAndrea J Rapkin
Department of Obstetrics and Gynecology, Los Angeles, California 90095, USA
J Pediatr Adolesc Gynecol 19:181-7. 2006..The purpose of the present study was to examine the associations among hormone concentrations, self-rated Tanner staging and dysmenorrhea, and to determine whether various psychosocial factors modulate these relationships... - Premenstrual syndrome in adolescents: diagnosis and treatmentAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Pediatr Endocrinol Rev 3:132-7. 2006..In adolescents, treatment should begin with education and lifestyle changes; however, many of the treatments used commonly in adults can also be employed safely in severe adolescent cases... - Decreased neuroactive steroids induced by combined oral contraceptive pills are not associated with mood changesAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095 1740, USA
Fertil Steril 85:1371-8. 2006..These neuroactive steroids are gamma-aminobutyric acid receptor agonists and are important in the modulation of affect and adaptation to stress... - Estrogen replacement therapy in the treatment of major depressive disorder in perimenopausal womenNatalie L Rasgon
Department of Psychiatry and Biobehavioral Science, University of California, Los Angeles, USA
J Clin Psychiatry 63:45-8. 2002..In depressed women who have minimal response to a selective serotonin reuptake inhibitor, ERT may augment response. Further controlled trials are needed... - Gynecological health of females with congenital heart diseaseMary M Canobbio
Ahmanson UCLA Center for Adult Congenital Heart Disease, UCLA School of Nursing, Box 951702, Los Angeles, CA 90095, USA
Int J Cardiol 98:379-87. 2005..Contraceptives must be selected according to individual patient profiles. Hormone replacement therapy is warranted for relief of menopausal symptoms as in the general population and should be relatively safe because estrogen dose is low... - Estrogen augmentation of antidepressants in perimenopausal depression: a pilot studyMelinda L Morgan
Laboratory of Behavioral Pharmacology, University of California Los Angeles Neuropsychiatric Institute and Hospital, Department of Psychiatry and Biobehavioral Sciences, 90024, USA
J Clin Psychiatry 66:774-80. 2005..To investigate the effects of estrogen augmentation on mood and memory in women with perimenopausal depression who had experienced a partial response to antidepressant medications... - Neurophysiologic changes during estrogen augmentation in perimenopausal depressionMelinda L Morgan
Laboratory of Brain, Behavior, and Pharmacology, Department of Psychiatry and Biobehavioral Sciences, UCLA Neuropsychiatric Institute, 760 Westwood Plaza, Suite 37 439, Los Angeles, CA 90024 1759, United States
Maturitas 56:54-60. 2007..We also assessed whether such changes were correlated with serum hormone levels... - Oral contraceptives and neuroactive steroidsAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States
Pharmacol Biochem Behav 84:628-34. 2006.... - Premenstrual disorders: prevalence, etiology and impactSharon A Winer
Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, 9400 Brighten Way, Suite 206, Beverly Hills, CA 90210, USA
J Reprod Med 51:339-47. 2006..Premenstrual disorders can have a significant negative impact on a woman's quality of life and work productivity... - Neuroactive steroid-serotonergic interaction: responses to an intravenous L-tryptophan challenge in women with premenstrual syndromeN Rasgon
Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, UCLA School of Medicine, Los Angeles, California 90095, USA
Eur J Endocrinol 145:25-33. 2001..Women with PMS demonstrated a more significant increase in allopregnanolone concentrations in response to L-TP challenge, which could be due to an initial low basal serotonergic tone in the luteal phase in the PMS group... - Multilevel local anesthetic nerve blockade for the treatment of vulvar vestibulitis syndromeAndrea J Rapkin
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA Los Angeles, CA, USA
Am J Obstet Gynecol 198:41.e1-5. 2008..Vulvar vestibulitis syndrome is a major cause of dyspareunia. This pilot study was designed to evaluate a novel treatment approach... - Treatment of premenstrual disordersRobin Kroll
Women s Clinical Research Center, Lakeview Medical Dental Building, 3216 NE 45th Place, Suite 1000, Seattle, WA 98105, USA
J Reprod Med 51:359-70. 2006..A new drospirenone-containing OC formulation that is administered for 24 days in a 28-day cycle has been shown to be effective in treating PMDD... - Diagnosis of premenstrual disordersLori A Futterman
San Diego Premenstrual Syndrome Clinic, Department of Psychiatry, University of California San Diego, 591 Camino de la Reina, Suite 705, San Diego, CA 92108, USA
J Reprod Med 51:349-58. 2006..Many women with a bothersome or debilitating premenstrual disorder go undiagnosed, either because they do not report their symptoms to a clinician or because the clinician has difficulty diagnosing the disorder...