Raghavendra B Rao

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Postnatal age influences hypoglycemia-induced neuronal injury in the rat brain
    Kathleen Ennis
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Brain Res 1224:119-26. 2008
  2. pmc Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus
    Raghavendra Rao
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA
    Nutr Neurosci 14:59-65. 2011
  3. pmc Neurochemical changes in the developing rat hippocampus during prolonged hypoglycemia
    Raghavendra Rao
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    J Neurochem 114:728-38. 2010
  4. pmc Iron in fetal and neonatal nutrition
    Raghavendra Rao
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA
    Semin Fetal Neonatal Med 12:54-63. 2007
  5. pmc Perinatal iron deficiency predisposes the developing rat hippocampus to greater injury from mild to moderate hypoxia-ischemia
    Raghavendra Rao
    Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Cereb Blood Flow Metab 27:729-40. 2007
  6. pmc Iron therapy for preterm infants
    Raghavendra Rao
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Mayo Mail Code 39, 420 Delaware Street, SE, Minneapolis, MN 55455, USA
    Clin Perinatol 36:27-42. 2009
  7. ncbi request reprint Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus
    Raghavendra Rao
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    J Nutr 133:3215-21. 2003
  8. ncbi request reprint Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain
    Asha Jyothi M Siddappa
    Division of Neonatology, Department of Pediatrics, University of Minnesota Medical School, Minneapolis 55455, USA
    Pediatr Res 53:800-7. 2003
  9. ncbi request reprint In vivo effect of chronic hypoxia on the neurochemical profile of the developing rat hippocampus
    Lakshmi Raman
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Brain Res Dev Brain Res 156:202-9. 2005
  10. pmc Region-specific changes in ascorbate concentration during rat brain development quantified by in vivo (1)H NMR spectroscopy
    Melissa Terpstra
    Radiology and Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA
    NMR Biomed 23:1038-43. 2010

Research Grants

Collaborators

Detail Information

Publications18

  1. pmc Postnatal age influences hypoglycemia-induced neuronal injury in the rat brain
    Kathleen Ennis
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Brain Res 1224:119-26. 2008
    ..Varying the duration of fasting did not alter the severity of regional cell injury. These results suggest that postnatal age influences the regional vulnerability to hypoglycemia-induced neuronal death in the rat brain...
  2. pmc Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus
    Raghavendra Rao
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA
    Nutr Neurosci 14:59-65. 2011
    ..The objective of the present study was to determine the long-term effects of perinatal iron deficiency and its treatment on hippocampal anatomy and neurochemistry in formerly iron-deficient young adult rats...
  3. pmc Neurochemical changes in the developing rat hippocampus during prolonged hypoglycemia
    Raghavendra Rao
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    J Neurochem 114:728-38. 2010
    ..Compensatory neurochemical changes maintain energy homeostasis during prolonged hypoglycemia in the developing hippocampus...
  4. pmc Iron in fetal and neonatal nutrition
    Raghavendra Rao
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA
    Semin Fetal Neonatal Med 12:54-63. 2007
    ..However, due to the potential for oxidant-mediated tissue injury, iron overload should be avoided in the perinatal period, especially in preterm infants...
  5. pmc Perinatal iron deficiency predisposes the developing rat hippocampus to greater injury from mild to moderate hypoxia-ischemia
    Raghavendra Rao
    Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Cereb Blood Flow Metab 27:729-40. 2007
    ....
  6. pmc Iron therapy for preterm infants
    Raghavendra Rao
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Mayo Mail Code 39, 420 Delaware Street, SE, Minneapolis, MN 55455, USA
    Clin Perinatol 36:27-42. 2009
    ....
  7. ncbi request reprint Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus
    Raghavendra Rao
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    J Nutr 133:3215-21. 2003
    ..An altered neurochemical profile of the developing hippocampus may underlie some of the cognitive deficits observed in human infants with perinatal iron deficiency...
  8. ncbi request reprint Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain
    Asha Jyothi M Siddappa
    Division of Neonatology, Department of Pediatrics, University of Minnesota Medical School, Minneapolis 55455, USA
    Pediatr Res 53:800-7. 2003
    ..Brain iron distribution during ID seems to be locally rather than globally regulated...
  9. ncbi request reprint In vivo effect of chronic hypoxia on the neurochemical profile of the developing rat hippocampus
    Lakshmi Raman
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Brain Res Dev Brain Res 156:202-9. 2005
    ..The altered hippocampal neurochemistry during its development may underlie some of the cognitive deficits present in human infants at risk of chronic hypoxia...
  10. pmc Region-specific changes in ascorbate concentration during rat brain development quantified by in vivo (1)H NMR spectroscopy
    Melissa Terpstra
    Radiology and Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA
    NMR Biomed 23:1038-43. 2010
    ....
  11. ncbi request reprint Developmental and regional changes in the neurochemical profile of the rat brain determined by in vivo 1H NMR spectroscopy
    Ivan Tkac
    Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Magn Reson Med 50:24-32. 2003
    ..The current data may serve as a reference for studies focused on developmental defects and pathologies using neonatal rat models...
  12. ncbi request reprint Quantification of vitamin C in the rat brain in vivo using short echo-time 1H MRS
    Melissa Terpstra
    Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Magn Reson Med 55:979-83. 2006
    ..Ascorbate concentrations measured using STEAM decreased with increasing postnatal rat age, in agreement with published brain ascorbate concentrations measured in vitro using high-performance liquid chromatography (HPLC)...
  13. pmc Gestational and lactational iron deficiency alters the developing striatal metabolome and associated behaviors in young rats
    Kay L Ward
    Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA
    J Nutr 137:1043-9. 2007
    ..These novel data imply that alterations in the metabolite profile of the striatum likely influence later neural functioning in early iron deficiency...
  14. pmc Effects of chronic hypoxia in developing rats on dendritic morphology of the CA1 subarea of the hippocampus and on fear-potentiated startle
    Lakshmi Raman
    Department of Pediatrics, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN 55415, USA
    Brain Res 1190:167-74. 2008
    ..These structural and functional alterations may contribute to the cognitive deficits seen in infants at risk for CH...
  15. ncbi request reprint Developmental changes in the expression of iron regulatory proteins and iron transport proteins in the perinatal rat brain
    Asha Jyothi M Siddappa
    Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    J Neurosci Res 68:761-75. 2002
    ..These developmental changes in IRP and transporter expression suggest potentially different time periods of brain structure vulnerability to iron deficiency or iron overload...
  16. pmc Postnatal age influences hypoglycemia-induced poly(ADP-ribose) polymerase-1 activation in the brain regions of rats
    Raghavendra Rao
    Department of Pediatrics, Center for Neurobehavioral Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Pediatr Res 66:642-7. 2009
    ..These data parallel the previously demonstrated pattern of hypoglycemia-induced brain injury and suggest that PARP-1 overactivation may determine age- and region-specific vulnerability during hypoglycemia...
  17. ncbi request reprint The role of chronic hypoxia in the development of neurocognitive abnormalities in preterm infants with bronchopulmonary dysplasia
    Lakshmi Raman
    Department of Pediatrics, Hennepin County Medical Center, Minneapolis, MN, USA
    Dev Sci 9:359-67. 2006
    ..However, due to the simultaneous occurrence of multiple neurodevelopmental risk factors, a primary or potentiating role for chronic hypoxia in these impairments has yet to be conclusively established...
  18. pmc The assessment of newborn iron stores at birth: a review of the literature and standards for ferritin concentrations
    Ashajyothi M Siddappa
    Division of Neonatology, Hennepin County Medical Center, Department of Pediatrics, University of Minnesota School of Medicine, Minneapolis, Minn, USA
    Neonatology 92:73-82. 2007
    ..The lack of normative newborn serum ferritin concentration data between 23 and 41 weeks has led to difficulty in establishing the incidence and degree of abnormal iron status in the neonatal period...

Research Grants1

  1. In vivo Substrate Utilization in the Newborn Rat Brain
    Raghavendra Rao; Fiscal Year: 2006
    ....