Christopher Rao

Summary

Affiliation: University of Illinois
Country: USA

Publications

  1. pmc Oscillatory Behavior of Neutrophils under Opposing Chemoattractant Gradients Supports a Winner-Take-All Mechanism
    Matthew B Byrne
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois, United States of America
    PLoS ONE 9:e85726. 2014
  2. pmc Computational design of orthogonal ribosomes
    Lon M Chubiz
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, 600 S Mathews Ave, Urbana, IL 61801, USA
    Nucleic Acids Res 36:4038-46. 2008
  3. pmc Engineering transcription factors with novel DNA-binding specificity using comparative genomics
    Tasha A Desai
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Nucleic Acids Res 37:2493-503. 2009
  4. pmc Identification and analysis of the putative pentose sugar efflux transporters in Escherichia coli
    Khushnuma Koita
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois, United States of America
    PLoS ONE 7:e43700. 2012
  5. pmc The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella
    Supreet Saini
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    PLoS Pathog 6:e1001025. 2010
  6. doi request reprint Expanding the synthetic biology toolbox: engineering orthogonal regulators of gene expression
    Christopher V Rao
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, United States
    Curr Opin Biotechnol 23:689-94. 2012
  7. ncbi request reprint Phosphatase localization in bacterial chemotaxis: divergent mechanisms, convergent principles
    Christopher V Rao
    Department of Bioengineering, University of California, Berkeley, CA 94720, USA
    Phys Biol 2:148-58. 2005
  8. doi request reprint The molecular basis of excitation and adaptation during chemotactic sensory transduction in bacteria
    Christopher V Rao
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Contrib Microbiol 16:33-64. 2009
  9. pmc Role of the mar-sox-rob regulon in regulating outer membrane porin expression
    Lon M Chubiz
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, 600 S Mathews Ave, Urbana, IL 61801, USA
    J Bacteriol 193:2252-60. 2011
  10. pmc FliZ induces a kinetic switch in flagellar gene expression
    Supreet Saini
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    J Bacteriol 192:6477-81. 2010

Collaborators

Detail Information

Publications10

  1. pmc Oscillatory Behavior of Neutrophils under Opposing Chemoattractant Gradients Supports a Winner-Take-All Mechanism
    Matthew B Byrne
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois, United States of America
    PLoS ONE 9:e85726. 2014
    ..In addition, we propose a winner-take-all mechanism allows the cells to avoid stagnation near local chemical maxima when migrating through a network of chemoattractant sources. ..
  2. pmc Computational design of orthogonal ribosomes
    Lon M Chubiz
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, 600 S Mathews Ave, Urbana, IL 61801, USA
    Nucleic Acids Res 36:4038-46. 2008
    ..In order to test the algorithm, we experimentally characterized a number of computationally designed o-ribosomes in Escherichia coli...
  3. pmc Engineering transcription factors with novel DNA-binding specificity using comparative genomics
    Tasha A Desai
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Nucleic Acids Res 37:2493-503. 2009
    ..Collectively, these results in this work demonstrate that comparative genomics can inform the design of bacterial transcription factors...
  4. pmc Identification and analysis of the putative pentose sugar efflux transporters in Escherichia coli
    Khushnuma Koita
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois, United States of America
    PLoS ONE 7:e43700. 2012
    ..None of the candidate transporters affected xylose concentrations. These results indicate that E. coli possesses multiple arabinose efflux transporters. They also provide a novel target for future metabolic engineering...
  5. pmc The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella
    Supreet Saini
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    PLoS Pathog 6:e1001025. 2010
    ..Collectively, our experimental and computational results enable us to deconstruct this complex circuit and determine the role of its individual components in regulating SPI1 gene expression dynamics...
  6. doi request reprint Expanding the synthetic biology toolbox: engineering orthogonal regulators of gene expression
    Christopher V Rao
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, United States
    Curr Opin Biotechnol 23:689-94. 2012
    ..While our toolbox is still spare, the situation is rapidly changing. This opinion discusses some recent approaches and open challenges in designing orthogonal regulators of gene expression in bacteria...
  7. ncbi request reprint Phosphatase localization in bacterial chemotaxis: divergent mechanisms, convergent principles
    Christopher V Rao
    Department of Bioengineering, University of California, Berkeley, CA 94720, USA
    Phys Biol 2:148-58. 2005
    ..While specific mechanisms are different, the underlying principles of phosphatase localization in E. coli and B. subtilis appear to be the same...
  8. doi request reprint The molecular basis of excitation and adaptation during chemotactic sensory transduction in bacteria
    Christopher V Rao
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Contrib Microbiol 16:33-64. 2009
    ..The one shared with E. coli, the receptor methylation system, is vastly different, as is the mechanism for conveying signals across the membrane...
  9. pmc Role of the mar-sox-rob regulon in regulating outer membrane porin expression
    Lon M Chubiz
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, 600 S Mathews Ave, Urbana, IL 61801, USA
    J Bacteriol 193:2252-60. 2011
    ..Finally, we found that the reduction in OmpF expression in a tolC mutant is due primarily to Rob. Collectively, this work further clarifies the coordinated role of MarA and Rob in regulating the expression of the outer membrane porins...
  10. pmc FliZ induces a kinetic switch in flagellar gene expression
    Supreet Saini
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    J Bacteriol 192:6477-81. 2010
    ..To understand its role in flagellar assembly, we investigated how FliZ affects gene expression dynamics. We demonstrate that FliZ participates in a positive-feedback loop that induces a kinetic switch in class 2 gene expression...