Ruiqiong Ran

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint A novel 165-kDa Golgin protein induced by brain ischemia and phosphorylated by Akt protects against apoptosis
    Ruiqiong Ran
    M I N D Institute and Department of Neurology, University of California at Davis Medical Center, University of California at Davis, Sacramento, CA 95817, USA
    Mol Cell Neurosci 36:392-407. 2007
  2. ncbi request reprint Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke
    Huichun Xu
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, California 95817, USA
    J Cereb Blood Flow Metab 28:1320-8. 2008
  3. ncbi request reprint Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study
    Yang Tang
    MIND Institute and Department of Neurology, University of California at Davis, Sacramento, California 95817, USA
    J Cereb Blood Flow Metab 26:1089-102. 2006
  4. ncbi request reprint The future of genomic profiling of neurological diseases using blood
    Frank R Sharp
    Department of Neurology and Medical Investigation of Neurodevelopmental Disorders Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA
    Arch Neurol 63:1529-36. 2006
  5. ncbi request reprint Hypoxia preconditioning in the brain
    Ruiqiong Ran
    Department of Neurology, M I N D Institute, University of California at Davis, Davis, CA 95817, USA
    Dev Neurosci 27:87-92. 2005
  6. ncbi request reprint Brain genomics of intracerebral hemorrhage
    Aigang Lu
    MIND Institute and Department of Neurology, University of California at Davis, Sacramento, California 95817, USA
    J Cereb Blood Flow Metab 26:230-52. 2006
  7. ncbi request reprint Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia
    Aigang Lu
    Department of Neurology, University of Cincinnati, Ohio 45267 0536, USA
    J Neurochem 81:355-64. 2002
  8. ncbi request reprint Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1
    Yang Tang
    Department of Neurology, University of Cincinnati, Vontz Center, Room 2327, 3125 Eden Avenue, Cincinnati, OH 45267 0536, USA
    Brain Res Mol Brain Res 132:155-67. 2004
  9. ncbi request reprint Genomics of the periinfarction cortex after focal cerebral ischemia
    Aigang Lu
    Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45267, USA
    J Cereb Blood Flow Metab 23:786-810. 2003
  10. ncbi request reprint Blood genomic expression profile for neuronal injury
    Yang Tang
    Department of Neurology, Neuroscience Program, University of Cincinnati, Vontz Center for Molecular Studies Room 2327, 3125 Eden Avenue, Cincinnati, OH 45267 0536, USA
    J Cereb Blood Flow Metab 23:310-9. 2003

Detail Information

Publications15

  1. ncbi request reprint A novel 165-kDa Golgin protein induced by brain ischemia and phosphorylated by Akt protects against apoptosis
    Ruiqiong Ran
    M I N D Institute and Department of Neurology, University of California at Davis Medical Center, University of California at Davis, Sacramento, CA 95817, USA
    Mol Cell Neurosci 36:392-407. 2007
    ..These data show that Akt phosphorylation of IIGP165 protects against apoptotic cell death, and add to evidence that the Golgi apparatus also plays a role in regulating apoptosis...
  2. ncbi request reprint Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke
    Huichun Xu
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, California 95817, USA
    J Cereb Blood Flow Metab 28:1320-8. 2008
    ..These results have wide ranging implications for similar disorders...
  3. ncbi request reprint Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study
    Yang Tang
    MIND Institute and Department of Neurology, University of California at Davis, Sacramento, California 95817, USA
    J Cereb Blood Flow Metab 26:1089-102. 2006
    ..These data provide insights into the inflammatory responses after stroke in humans, and should be helpful in diagnosis, understanding etiology and pathogenesis, and guiding acute treatment and development of new treatments for stroke...
  4. ncbi request reprint The future of genomic profiling of neurological diseases using blood
    Frank R Sharp
    Department of Neurology and Medical Investigation of Neurodevelopmental Disorders Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA
    Arch Neurol 63:1529-36. 2006
    ..Although all of these studies are still preliminary basic scientific endeavors, they suggest that this approach will have clinical applications to neurological diseases in humans...
  5. ncbi request reprint Hypoxia preconditioning in the brain
    Ruiqiong Ran
    Department of Neurology, M I N D Institute, University of California at Davis, Davis, CA 95817, USA
    Dev Neurosci 27:87-92. 2005
    ..This hypoxia preconditioning has potential clinical usefulness in protecting high-risk newborns or to provide protection prior to surgery...
  6. ncbi request reprint Brain genomics of intracerebral hemorrhage
    Aigang Lu
    MIND Institute and Department of Neurology, University of California at Davis, Sacramento, California 95817, USA
    J Cereb Blood Flow Metab 26:230-52. 2006
    ..These genomic responses to ICH potentially provide new therapeutic targets for treatment...
  7. ncbi request reprint Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia
    Aigang Lu
    Department of Neurology, University of Cincinnati, Ohio 45267 0536, USA
    J Neurochem 81:355-64. 2002
    ..The data show that geldanamycin protects brain from focal ischemia and that this may be due, at least in part, to geldanamycin stimulation of heat shock gene transcription...
  8. ncbi request reprint Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1
    Yang Tang
    Department of Neurology, University of Cincinnati, Vontz Center, Room 2327, 3125 Eden Avenue, Cincinnati, OH 45267 0536, USA
    Brain Res Mol Brain Res 132:155-67. 2004
    ....
  9. ncbi request reprint Genomics of the periinfarction cortex after focal cerebral ischemia
    Aigang Lu
    Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45267, USA
    J Cereb Blood Flow Metab 23:786-810. 2003
    ..Genes regulated acutely after stroke may modulate cell survival and death; also, late regulated genes may be related to tissue repair and functional recovery...
  10. ncbi request reprint Blood genomic expression profile for neuronal injury
    Yang Tang
    Department of Neurology, Neuroscience Program, University of Cincinnati, Vontz Center for Molecular Studies Room 2327, 3125 Eden Avenue, Cincinnati, OH 45267 0536, USA
    J Cereb Blood Flow Metab 23:310-9. 2003
    ....
  11. pmc Hsp70 mutant proteins modulate additional apoptotic pathways and improve cell survival
    Ruiqiong Ran
    Department of Neurology, Vontz Center for Molecular Studies, University of Cincinnati, Room 2327, 3125 Eden Avenue, Cincinnati, OH 45267 0536, USA
    Cell Stress Chaperones 9:229-42. 2004
    ..Hsp70 mutants represent a possible approach to antiapoptotic biotherapeutics. Similar rational designs could be used to engineer inhibitors of additional caspase family members...
  12. ncbi request reprint Glutamate receptor blockade attenuates glucose hypermetabolism in perihematomal brain after experimental intracerebral hemorrhage in rat
    Timothy D Ardizzone
    Department of Neurology, University of Cincinnati College of Medicine, Ohio, USA
    Stroke 35:2587-91. 2004
    ..To develop successful treatments, we must learn more about the effects of hemorrhage on brain tissue. In this study, we investigated the acute metabolic effects of intrastriatal hemorrhage in rat brain...
  13. pmc Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling
    Ruiqiong Ran
    Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45267, USA
    Genes Dev 18:1466-81. 2004
    ..These results provide significant novel insights into the molecular mechanism for the pro-apoptotic behavior of Hsp70 in death-receptor-mediated cell death...
  14. pmc Reperfusion activates metalloproteinases that contribute to neurovascular injury
    Aigang Lu
    Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0532
    Exp Neurol 210:549-59. 2008
    ..Administering AHA 30 min before reperfusion decreased MMP-9 activation and neurovascular injury in ischemic cerebral cortex...
  15. pmc Hypoxic preconditioning protects against ischemic brain injury
    Frank R Sharp
    Department of Neurology, University of Cincinnati, Ohio 45267, USA
    NeuroRx 1:26-35. 2004
    ..Understanding the mechanisms and genes involved in hypoxic tolerance may provide new therapeutic targets to treat ischemic injury and enhance recovery...