Rangasamy Ramanathan

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi request reprint A randomized, multicenter masked comparison trial of poractant alfa (Curosurf) versus beractant (Survanta) in the treatment of respiratory distress syndrome in preterm infants
    Rangasamy Ramanathan
    Department of Pediatrics, Division of Neonatal Medicine, Women s and Children s Hospital and Good Samaritan Hospital, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Am J Perinatol 21:109-19. 2004
  2. doi request reprint Nasal intermittent positive pressure ventilation after surfactant treatment for respiratory distress syndrome in preterm infants <30 weeks' gestation: a randomized, controlled trial
    R Ramanathan
    USC Division of Neonatal Medicine, LAC USC Medical Center, Good Samaritan Hospital and Children s Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA, USA
    J Perinatol 32:336-43. 2012
  3. ncbi request reprint Surfactant therapy in preterm infants with respiratory distress syndrome and in near-term or term newborns with acute RDS
    R Ramanathan
    Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA
    J Perinatol 26:S51-6; discussion S63-4. 2006
  4. doi request reprint Evidence vs experience in neonatal medicine
    R Ramanathan
    Department of Pediatrics, Women s and Children s Hospital, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Perinatol 28:S2-3. 2008
  5. doi request reprint Lung protective ventilatory strategies in very low birth weight infants
    R Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Women s and Children s Hospital and Childrens Hospital Los Angeles, Keck School of Medicine University of Southern California, Los Angeles, CA, USA
    J Perinatol 28:S41-6. 2008
  6. doi request reprint Optimal ventilatory strategies and surfactant to protect the preterm lungs
    Rangasamy Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Women s and Children s Hospital, Keck School of Medicine, University of Southern California, Los Angeles, Calif 90033, USA
    Neonatology 93:302-8. 2008
  7. doi request reprint Choosing a right surfactant for respiratory distress syndrome treatment
    Rangasamy Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Women s and Children s Hospital, University of Southern California, Los Angeles, CA 90033, USA
    Neonatology 95:1-5. 2009
  8. doi request reprint Animal-derived surfactants: where are we? The evidence from randomized, controlled clinical trials
    R Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Women s and Children s Hospital and Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Perinatol 29:S38-43. 2009
  9. doi request reprint Nasal respiratory support through the nares: its time has come
    R Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Los Angeles County University of Southern California Medical Center and Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Perinatol 30:S67-72. 2010
  10. pmc Longitudinal assessment of hemoglobin oxygen saturation in preterm and term infants in the first six months of life
    Carl E Hunt
    Department of Pediatrics, University of Toledo Health Sciences Center, Toledo, OH, USA
    J Pediatr 159:377-383.e1. 2011

Collaborators

Detail Information

Publications34

  1. ncbi request reprint A randomized, multicenter masked comparison trial of poractant alfa (Curosurf) versus beractant (Survanta) in the treatment of respiratory distress syndrome in preterm infants
    Rangasamy Ramanathan
    Department of Pediatrics, Division of Neonatal Medicine, Women s and Children s Hospital and Good Samaritan Hospital, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Am J Perinatol 21:109-19. 2004
    ..05) than either beractant or poractant alfa (100 mg/kg dosing) in infants < or =32 weeks gestation with RDS...
  2. doi request reprint Nasal intermittent positive pressure ventilation after surfactant treatment for respiratory distress syndrome in preterm infants <30 weeks' gestation: a randomized, controlled trial
    R Ramanathan
    USC Division of Neonatal Medicine, LAC USC Medical Center, Good Samaritan Hospital and Children s Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA, USA
    J Perinatol 32:336-43. 2012
    ....
  3. ncbi request reprint Surfactant therapy in preterm infants with respiratory distress syndrome and in near-term or term newborns with acute RDS
    R Ramanathan
    Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA
    J Perinatol 26:S51-6; discussion S63-4. 2006
    ..In near-term or term newborns with acute RDS, surfactant therapy has been shown to be 70% effective in improving respiratory failure...
  4. doi request reprint Evidence vs experience in neonatal medicine
    R Ramanathan
    Department of Pediatrics, Women s and Children s Hospital, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Perinatol 28:S2-3. 2008
  5. doi request reprint Lung protective ventilatory strategies in very low birth weight infants
    R Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Women s and Children s Hospital and Childrens Hospital Los Angeles, Keck School of Medicine University of Southern California, Los Angeles, CA, USA
    J Perinatol 28:S41-6. 2008
    ..Initial steps in the management of preterm infants may also include sustained inflation to establish functional residual capacity, followed by noninvasive ventilation to minimize lung injury and subsequent development of BPD...
  6. doi request reprint Optimal ventilatory strategies and surfactant to protect the preterm lungs
    Rangasamy Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Women s and Children s Hospital, Keck School of Medicine, University of Southern California, Los Angeles, Calif 90033, USA
    Neonatology 93:302-8. 2008
    ....
  7. doi request reprint Choosing a right surfactant for respiratory distress syndrome treatment
    Rangasamy Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Women s and Children s Hospital, University of Southern California, Los Angeles, CA 90033, USA
    Neonatology 95:1-5. 2009
    ..Additional studies of administering surfactant non-invasively via laryngeal mask airway in preterm infants weighing >1,200 g and as an aerosol preparation are currently in progress...
  8. doi request reprint Animal-derived surfactants: where are we? The evidence from randomized, controlled clinical trials
    R Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Women s and Children s Hospital and Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Perinatol 29:S38-43. 2009
    ..Further studies are needed comparing animal-derived surfactants with the newer generation of synthetic surfactants...
  9. doi request reprint Nasal respiratory support through the nares: its time has come
    R Ramanathan
    Division of Neonatal Medicine, Department of Pediatrics, Los Angeles County University of Southern California Medical Center and Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Perinatol 30:S67-72. 2010
    ....
  10. pmc Longitudinal assessment of hemoglobin oxygen saturation in preterm and term infants in the first six months of life
    Carl E Hunt
    Department of Pediatrics, University of Toledo Health Sciences Center, Toledo, OH, USA
    J Pediatr 159:377-383.e1. 2011
    ..To report longitudinal home recordings of hemoglobin O(2) saturation by pulse oximetry (Spo(2)) during unperturbed sleep in preterm and term infants...
  11. ncbi request reprint Cardiovascular effects of low-dose dexamethasone in very low birth weight neonates with refractory hypotension
    Shahab Noori
    USC Division of Neonatal Medicine, Childrens Hospital Los Angeles, CA 90027, USA
    Biol Neonate 89:82-7. 2006
    ..Furthermore, there are no sufficient data available on whether a smaller dose of dexamethasone would also be effective in treating refractory hypotension...
  12. ncbi request reprint Constitutive IL-10 expression by lung inflammatory cells and risk for bronchopulmonary dysplasia
    Arlene Garingo
    Division of Neonatology, Department of Pediatrics, Women s and Children s Hospital, Keck School of Medicine, University of Southern California, Los Angeles, California, 90033, USA
    Pediatr Res 61:197-202. 2007
    ..In contrast, constitutive IL-10 production within d 1-3 of life correlated with, and predicted the incidence of BPD in the highly vulnerable very premature infants...
  13. ncbi request reprint Systemic to pulmonary collaterals in very low birth weight infants: color doppler detection of systemic to pulmonary connections during neonatal and early infancy period
    R J Acherman
    Department of Pediatrics, University of Southern California, Women s and Children s Hospital Los Angeles, CA 90033, USA
    Pediatrics 105:528-32. 2000
    ....
  14. ncbi request reprint Concurrent use of indomethacin and dexamethasone increases the risk of spontaneous intestinal perforation in very low birth weight neonates
    L Paquette
    USC Division of Neonatal Medicine, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
    J Perinatol 26:486-92. 2006
    ..However, no study has specifically investigated the role of the concurrent use of indomethacin and dexamethasone in SIP...
  15. ncbi request reprint High frequency ventilation: basic concepts and clinical application
    R Ramanathan
    Department of Pediatrics, Women s and Children s Hospital, University of Southern California, School of Medicine, Los Angeles, 90033, USA
    Indian J Pediatr 67:3-8. 2000
    ..Ideally, the clinician or the operator should be familiar with the basic concepts of different high frequency ventilators to achieve maximal benefits from using these devices in infants with respiratory failure...
  16. doi request reprint The development of the circadian heart rate rhythm (CHR) in Asian infants
    Toke Hoppenbrouwers
    University of Southern California Division of Neonatal Medicine, LAC USC Medical Center and Childrens Hospital Los Angeles, Los Angeles, CA 90033, USA
    Early Hum Dev 88:555-61. 2012
    ..To test the hypothesis that term-born Asian infants, at reduced risk to die of Sudden Infant Death Syndrome (SIDS) exhibit a circadian heart rate rhythm (CHR) at a later age than non-Asian term infants...
  17. pmc A physiologic reduced oxygen protocol decreases the incidence of threshold retinopathy of prematurity
    Kenneth W Wright
    Cedars Sinai Medical Center, Los Angeles, California, USA
    Trans Am Ophthalmol Soc 104:78-84. 2006
    ....
  18. ncbi request reprint Risk of need for extracorporeal membrane oxygenation support in neonates with congenital diaphragmatic hernia treated with inhaled nitric oxide
    Matthew Sebald
    USC Division of Neonatal Medicine, Childrens Hospital Los Angeles and the Women s and Children s Hospital, LAC USC Medical Center, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
    J Perinatol 24:143-6. 2004
    ..Therefore, in this study, we sought to determine the risk factors for the need for ECMO in a cohort of 27 neonates with isolated left CDH and hypoxemic respiratory failure treated with iNO...
  19. pmc Changes in the DP-gram during the preterm and early postnatal period
    Carolina Abdala
    House Ear Institute, 2100 West Third Street, Children s Auditory Research and Evaluation Center, Los Angeles, California 90057, USA
    Ear Hear 29:512-23. 2008
    ..This information provides normative guidelines for audiologists or hearing screeners using DPOAEs to monitor infant hearing status...
  20. ncbi request reprint Precursors of cardiorespiratory events in infants detected by home memory monitor
    Carl E Hunt
    Department of Pediatrics, University of Toledo Health Sciences Center, Toledo, Ohio 43699, USA
    Pediatr Pulmonol 43:87-98. 2008
    ..Thus, conventional and extreme events do not occur de novo but rather are preceded by autonomic instability of the cardiorespiratory system...
  21. ncbi request reprint Interleukin-1beta in the bronchoalveolar lavage fluid of premature neonates: a marker for maternal chorioamnionitis and predictor of adverse neonatal outcome
    R G Cayabyab
    Division of Neonatology and Allergy Immunology, Department of Pediatrics, Women s and Children s Hospital, LAC and USC Medical Center, University of Southern California School of Medicine, Los Angeles, California 90033, USA
    J Matern Fetal Neonatal Med 14:205-11. 2003
    ..To determine whether the presence of the proinflammatory cytokine interleukin (IL)-1beta in the lungs of preterm infants immediately after birth was associated with maternal inflammation and could predict adverse neonatal outcome...
  22. doi request reprint Multicenter crossover study of automated control of inspired oxygen in ventilated preterm infants
    Nelson Claure
    University of Miami, Miller School of Medicine, Department of Pediatrics, Division of Neonatology, PO Box 016960, R 131, Miami, FL 33101, USA
    Pediatrics 127:e76-83. 2011
    ....
  23. doi request reprint Intrauterine exposure to mycophenolate mofetil and multiple congenital anomalies in a newborn: possible teratogenic effect
    Paige Jackson
    Center for Fetal and Neonatal Medicine, USC Division of Neonatal Medicine, Department of Pediatrics, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA
    Am J Med Genet A 149:1231-6. 2009
    ....
  24. ncbi request reprint Two-year outcome of infants weighing 600 grams or less at birth and born 1994 through 1998
    Matthew P Sweet
    University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Obstet Gynecol 101:18-23. 2003
    ..To assess the neurologic and developmental outcome at 2 years of age in preterm infants with birth weights 600 g or lower...
  25. ncbi request reprint Synchronized intermittent mandatory ventilation and pressure support: to sync or not to sync? Pressure support or no pressure support?
    Rangasamy Ramanathan
    Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA
    J Perinatol 25:S23-5; discussion S26-7. 2005
    ....
  26. ncbi request reprint A rare presentation of Pompe disease with massive hypertrophic cardiomyopathy at birth
    Shahab Noori
    Division of Neonatology, Women s and Children s Hospital, Keck School of Medicine, University of Southern California, Los Angeles, USA
    J Perinat Med 30:517-21. 2002
    ..Diagnosis was confirmed by low alpha-glucosidase activity. The histopathology and electron microscopic findings were consistent with Pompe disease. This is the second reported case of Pompe disease presenting at delivery...
  27. ncbi request reprint Expression of transforming growth factor beta (TGF-b1) by human preterm lung inflammatory cells
    K Y Kwong
    Division of Allergy Immunology, Department of Pediatrics, Los Angeles County, Los Angeles, California, USA
    Life Sci 79:2349-56. 2006
    ..In conclusion, lung inflammatory cells from premature infants are a source of TGF-beta1 but LPS does not regulate TGF-b1 production in these cells...
  28. ncbi request reprint Transitional hypothermia in preterm newborns
    D R Bhatt
    1Kaiser Permanente, Fontana, CA, USA
    J Perinatol 27:S45-7. 2007
    ..Increased efforts will be necessary to prevent early hypothermia in very preterm infants, especially with respect to the environmental conditions of the delivery room itself...
  29. doi request reprint Effects of low oxygen saturation limits on the ductus arteriosus in extremely low birth weight infants
    S Noori
    Department of Pediatrics, Neonatal Perinatal Medicine, The Children s Hospital, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Perinatol 29:553-7. 2009
    ....
  30. ncbi request reprint Cardiorespiratory events recorded on home monitors: Comparison of healthy infants with those at increased risk for SIDS
    R Ramanathan
    Department of Pediatrics, Yale Medical School, Box 208064, New Haven, CT 06520-8064, USA
    JAMA 285:2199-207. 2001
    ..These data should be important for designing future monitors and determining if an infant is likely to be at risk for a cardiorespiratory event...
  31. ncbi request reprint Lipopolysaccharide-induced tumor necrosis factor-alpha and IL-10 production by lung macrophages from preterm and term neonates
    M J Blahnik
    Division of Neonatology, Department of Pediatrics, Women's and Children's Hospital, University of Southern California School of Medicine, Los Angeles, California 90033, USA
    Pediatr Res 50:726-31. 2001
    ..Overall, the data are consistent with a pro- versus antiinflammatory imbalance that may bear functional significance on the pathogenesis of chronic lung disease...
  32. ncbi request reprint Bioactive transforming growth factor-beta in the lungs of extremely low birthweight neonates predicts the need for home oxygen supplementation
    C Lecart
    Division of Neonatology, Department of Pediatrics, Women s and Children s Hospital, LAC USC Medical Center, Los Angeles, CA 90033, USA
    Biol Neonate 77:217-23. 2000
    ..We conclude that abundant BA- TGF-beta is present in the lungs of preterm infants and speculate that it may be involved in inflammatory and repair processes encountered in acute and chronic lung disease...
  33. ncbi request reprint Meconium-stained amniotic fluid and neonatal morbidity in near-term and term deliveries with acute histologic chorioamnionitis and/or funisitis
    S Rao
    University of Southern California Keck School of Medicine, Department of Pediatrics, Division of Neonatology, Women's and Children's Hospital, 1240 North Mission Road, Los Angeles, CA 90033, USA
    J Perinatol 21:537-40. 2001
    ..The presence of meconium in the amniotic fluid should alert the physician to the potential for infection and increased neonatal morbidity...
  34. ncbi request reprint Cardiorespiratory events detected by home memory monitoring and one-year neurodevelopmental outcome
    Carl E Hunt
    National Center on Sleep Disorders Research, National Heart, Lung, and Blood Institute, 6705 Rockledge Dr, Ste 6022, Bethesda, MD 20892 7993, USA
    J Pediatr 145:465-71. 2004
    ..To determine if infants with cardiorespiratory events detected by home memory monitoring during early infancy have decreased neurodevelopmental performance...