Jayanth Ramadoss

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. pmc Alcohol-induced alterations in maternal uterine endothelial proteome: a quantitative iTRAQ mass spectrometric approach
    Jayanth Ramadoss
    Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555, USA
    Reprod Toxicol 34:538-44. 2012
  2. pmc Vascular effects of maternal alcohol consumption
    Jayanth Ramadoss
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, USA
    Am J Physiol Heart Circ Physiol 303:H414-21. 2012
  3. pmc Multiplexed digital quantification of binge-like alcohol-mediated alterations in maternal uterine angiogenic mRNA transcriptome
    Jayanth Ramadoss
    Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Physiol Genomics 44:622-8. 2012
  4. pmc 2-D DIGE uterine endothelial proteomic profile for maternal chronic binge-like alcohol exposure
    Jayanth Ramadoss
    Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin 53715, USA
    J Proteomics 74:2986-94. 2011
  5. pmc Endothelial caveolar hub regulation of adenosine triphosphate-induced endothelial nitric oxide synthase subcellular partitioning and domain-specific phosphorylation
    Jayanth Ramadoss
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, WI 53715, USA
    Hypertension 59:1052-9. 2012
  6. ncbi request reprint Endothelial caveolar subcellular domain regulation of endothelial nitric oxide synthase
    Jayanth Ramadoss
    Department of Obstetrics and Gynaecology, University of Texas Medical Branch, Galveston, TX, USA
    Clin Exp Pharmacol Physiol 40:753-64. 2013
  7. pmc Estradiol-17β and its cytochrome P450- and catechol-O-methyltransferase-derived metabolites selectively stimulate production of prostacyclin in uterine artery endothelial cells: role of estrogen receptor-α versus estrogen receptor-β
    Sheikh O Jobe
    Department of Obstetrics and Gynecology, Perinatal Research Laboratories, Atrium B Meriter Hospital, 202 S Park St, Madison, WI, 53715, USA
    Hypertension 61:509-18. 2013
  8. ncbi request reprint Chronic binge alcohol exposure during pregnancy impairs rat maternal uterine vascular function
    Kaviarasan Subramanian
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas
    Alcohol Clin Exp Res 38:1832-8. 2014
  9. doi request reprint Alcohol and maternal uterine vascular adaptations during pregnancy-part I: effects of chronic in vitro binge-like alcohol on uterine endothelial nitric oxide system and function
    Jayanth Ramadoss
    Department of Obstetrics and Gynecology, Perinatal Research Laboratories, University of Wisconsin, Madison, Wisconsin 53715, USA
    Alcohol Clin Exp Res 35:1686-93. 2011
  10. ncbi request reprint Effects of L-glutamine supplementation on maternal and fetal hemodynamics in gestating ewes exposed to alcohol
    Onkar B Sawant
    Department of Veterinary Physiology and Pharmacology and Michael E DeBakey Institute, College of Veterinary Medicine and Biomedical Sciences, 4466 Texas A and M University, College Station, TX, 77843 4466, USA
    Amino Acids 46:1981-96. 2014

Collaborators

  • Kunju Sathishkumar
  • Dong Bao Chen
  • Kaviarasan Subramanian
  • Sheikh O Jobe
  • Onkar B Sawant
  • Gary D Hankins
  • George R Saade
  • Vishal D Naik
  • Guoyao Wu
  • Shannon E Washburn
  • Vijayakumar Chinnathambi
  • Ronald R Magness
  • Chandra Yallampalli
  • Chandrashekar Yallampalli
  • Chandrasekhar Yallampalli
  • Andrew J Wargin
  • Meena Balakrishnan
  • Sean N Fling

Detail Information

Publications14

  1. pmc Alcohol-induced alterations in maternal uterine endothelial proteome: a quantitative iTRAQ mass spectrometric approach
    Jayanth Ramadoss
    Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555, USA
    Reprod Toxicol 34:538-44. 2012
    ..To quantitate alcohol-induced alterations in the maternal uterine endothelial proteome utilizing iTRAQ-based mass spectrometry...
  2. pmc Vascular effects of maternal alcohol consumption
    Jayanth Ramadoss
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, USA
    Am J Physiol Heart Circ Physiol 303:H414-21. 2012
    ..Data presented in this review will illustrate the importance of the maternal vasculature in the pathogenesis of fetal alcohol spectrum disorders and that more studies are warranted in this field...
  3. pmc Multiplexed digital quantification of binge-like alcohol-mediated alterations in maternal uterine angiogenic mRNA transcriptome
    Jayanth Ramadoss
    Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Physiol Genomics 44:622-8. 2012
    ..The tripartite digital gene expression system is therefore a valuable tool to answer many additional questions about FASD from both mechanistic as well as ameliorative perspectives...
  4. pmc 2-D DIGE uterine endothelial proteomic profile for maternal chronic binge-like alcohol exposure
    Jayanth Ramadoss
    Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin 53715, USA
    J Proteomics 74:2986-94. 2011
    ..The current study also demonstrates a great need to utilize proteomic approaches for diagnostic, mechanistic and therapeutic aspects of FASD...
  5. pmc Endothelial caveolar hub regulation of adenosine triphosphate-induced endothelial nitric oxide synthase subcellular partitioning and domain-specific phosphorylation
    Jayanth Ramadoss
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, WI 53715, USA
    Hypertension 59:1052-9. 2012
    ..Furthermore, these subcellular domain-specific phosphorylation/dephosphorylation events provide evidence relating to eNOS spatio-temporal dynamics...
  6. ncbi request reprint Endothelial caveolar subcellular domain regulation of endothelial nitric oxide synthase
    Jayanth Ramadoss
    Department of Obstetrics and Gynaecology, University of Texas Medical Branch, Galveston, TX, USA
    Clin Exp Pharmacol Physiol 40:753-64. 2013
    ..that have life-long deleterious health consequences that predispose the offspring to develop hypertensive disease, Type 2 diabetes and adiposity. ..
  7. pmc Estradiol-17β and its cytochrome P450- and catechol-O-methyltransferase-derived metabolites selectively stimulate production of prostacyclin in uterine artery endothelial cells: role of estrogen receptor-α versus estrogen receptor-β
    Sheikh O Jobe
    Department of Obstetrics and Gynecology, Perinatal Research Laboratories, Atrium B Meriter Hospital, 202 S Park St, Madison, WI, 53715, USA
    Hypertension 61:509-18. 2013
    ..These findings also shed light on the complexities of estrogen signaling via its metabolism and the functional heterogeneity of the ERs...
  8. ncbi request reprint Chronic binge alcohol exposure during pregnancy impairs rat maternal uterine vascular function
    Kaviarasan Subramanian
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas
    Alcohol Clin Exp Res 38:1832-8. 2014
    ..We herein hypothesized that chronic binge-like alcohol results in uterine vascular dysfunction and impairs maternal uterine artery reactivity to vasoconstrictors and dilators...
  9. doi request reprint Alcohol and maternal uterine vascular adaptations during pregnancy-part I: effects of chronic in vitro binge-like alcohol on uterine endothelial nitric oxide system and function
    Jayanth Ramadoss
    Department of Obstetrics and Gynecology, Perinatal Research Laboratories, University of Wisconsin, Madison, Wisconsin 53715, USA
    Alcohol Clin Exp Res 35:1686-93. 2011
    ..To study the direct effects of alcohol on uterine vascular adaptations, we further investigated the effects of alcohol on estradiol-17β-induced uterine angiogenesis in vitro...
  10. ncbi request reprint Effects of L-glutamine supplementation on maternal and fetal hemodynamics in gestating ewes exposed to alcohol
    Onkar B Sawant
    Department of Veterinary Physiology and Pharmacology and Michael E DeBakey Institute, College of Veterinary Medicine and Biomedical Sciences, 4466 Texas A and M University, College Station, TX, 77843 4466, USA
    Amino Acids 46:1981-96. 2014
    ..Further studies are warranted to elucidate mechanisms responsible for alcohol-induced programming of maternal uterine artery and fetal circulation adaptations in pregnancy. ..
  11. pmc High-throughput caveolar proteomic signature profile for maternal binge alcohol consumption
    Jayanth Ramadoss
    Department of Obstetrics and Gynecology, Perinatal Research Laboratories, University of Wisconsin, Atrium B Meriter Hospital, 202 South Park Street Madison, WI 53715, USA
    Alcohol 44:691-7. 2010
    ..These data demonstrate that the caveolar proteomic signature created by alcohol shows a promising direction for early detection of FASD...
  12. pmc A novel role for an endothelial adrenergic receptor system in mediating catecholestradiol-induced proliferation of uterine artery endothelial cells
    Sheikh O Jobe
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, WI, USA
    Hypertension 58:874-81. 2011
    ....
  13. pmc Testosterone alters maternal vascular adaptations: role of the endothelial NO system
    Vijayakumar Chinnathambi
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555 1062, USA
    Hypertension 61:647-54. 2013
    ..T may induce the increased vascular resistance associated with pregnancy-induced hypertension...
  14. pmc Interactive effects of in vitro binge-like alcohol and ATP on umbilical endothelial nitric oxide synthase post-translational modifications and redox modulation
    Kaviarasan Subramanian
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, USA
    Reprod Toxicol 43:94-101. 2014
    ..Thus, alcohol effects on multi-site post-translational modifications and redox switches related to vasodilatory eNOS underscore the necessity for investigating alcohol-induced gestational vascular dysfunction. ..