J Daniel Ragland

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Working memory for complex figures: an fMRI comparison of letter and fractal n-back tasks
    J Daniel Ragland
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Neuropsychology 16:370-9. 2002
  2. ncbi request reprint Event-related fMRI of frontotemporal activity during word encoding and recognition in schizophrenia
    J Daniel Ragland
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Psychiatry 161:1004-15. 2004
  3. ncbi request reprint Levels-of-processing effect on internal source monitoring in schizophrenia
    J Daniel Ragland
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Psychol Med 36:641-8. 2006
  4. ncbi request reprint Functional magnetic resonance imaging of internal source monitoring in schizophrenia: recognition with and without recollection
    J Daniel Ragland
    Department of Psychiatry, Brain Behavior Laboratory, 3400 Spruce Street, University of Pennsylvania, Philadelphia, PA 19104, USA
    Schizophr Res 87:160-71. 2006
  5. ncbi request reprint Profiles of neuropsychologic function in schizophrenia
    J Daniel Ragland
    Department of Psychiatry, Brain Behavior Laboratory, University of Pennsylvania School of Medicine, Gates Building 10th Floor, Philadelphia, PA 19104, USA
    Curr Psychiatry Rep 5:299-302. 2003
  6. ncbi request reprint Levels-of-processing effect on frontotemporal function in schizophrenia during word encoding and recognition
    J Daniel Ragland
    Department of Psychiatry, 10th Floor Gates Bldg HUP, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Psychiatry 162:1840-8. 2005
  7. ncbi request reprint Visual attention circuitry in schizophrenia investigated with oddball event-related functional magnetic resonance imaging
    Raquel E Gur
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Psychiatry 164:442-9. 2007
  8. doi request reprint Not pitch perfect: sensory contributions to affective communication impairment in schizophrenia
    David I Leitman
    Department of Psychiatry Neuropsychiatry Program, Brain Behavior Laboratory, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4283, USA
    Biol Psychiatry 70:611-8. 2011
  9. pmc Alterations of fronto-temporal connectivity during word encoding in schizophrenia
    Daniel H Wolf
    University of Pennsylvania, Department of Psychiatry, Philadelphia, PA 19104, USA
    Psychiatry Res 154:221-32. 2007
  10. ncbi request reprint Prognostic variables at intake and long-term level of function in schizophrenia
    Steven J Siegel
    Division of Neuropsychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Psychiatry 163:433-41. 2006

Detail Information

Publications34

  1. ncbi request reprint Working memory for complex figures: an fMRI comparison of letter and fractal n-back tasks
    J Daniel Ragland
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Neuropsychology 16:370-9. 2002
    ..Results support fractal n-back validity and indicate substantial overlap in working memory functions of dorsal and ventral PFC...
  2. ncbi request reprint Event-related fMRI of frontotemporal activity during word encoding and recognition in schizophrenia
    J Daniel Ragland
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Psychiatry 161:1004-15. 2004
    ..Neuropsychological studies have demonstrated verbal episodic memory deficits in schizophrenia during word encoding and retrieval. This study examined neural substrates of memory in an analysis that controlled for successful retrieval...
  3. ncbi request reprint Levels-of-processing effect on internal source monitoring in schizophrenia
    J Daniel Ragland
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Psychol Med 36:641-8. 2006
    ..The current study investigates whether providing semantic organizational strategies can also normalize patients' internal source-monitoring performance...
  4. ncbi request reprint Functional magnetic resonance imaging of internal source monitoring in schizophrenia: recognition with and without recollection
    J Daniel Ragland
    Department of Psychiatry, Brain Behavior Laboratory, 3400 Spruce Street, University of Pennsylvania, Philadelphia, PA 19104, USA
    Schizophr Res 87:160-71. 2006
    ..Activation in these areas was associated with worse positive and negative symptoms, but did not correlate with performance, suggesting inefficient rather than compensatory activation...
  5. ncbi request reprint Profiles of neuropsychologic function in schizophrenia
    J Daniel Ragland
    Department of Psychiatry, Brain Behavior Laboratory, University of Pennsylvania School of Medicine, Gates Building 10th Floor, Philadelphia, PA 19104, USA
    Curr Psychiatry Rep 5:299-302. 2003
    ..Finally, the relation of cognitive ability to functional outcome is described, and it is explained why there is a resurgent interest in remediation efforts. The article closes with suggestions for future directions...
  6. ncbi request reprint Levels-of-processing effect on frontotemporal function in schizophrenia during word encoding and recognition
    J Daniel Ragland
    Department of Psychiatry, 10th Floor Gates Bldg HUP, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Psychiatry 162:1840-8. 2005
    ..Patients with schizophrenia improve episodic memory accuracy when given organizational strategies through levels-of-processing paradigms. This study tested if improvement is accompanied by normalized frontotemporal function...
  7. ncbi request reprint Visual attention circuitry in schizophrenia investigated with oddball event-related functional magnetic resonance imaging
    Raquel E Gur
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Psychiatry 164:442-9. 2007
    ..Cerebral activity underlying abnormal attention can be examined with event-related functional magnetic resonance imaging...
  8. doi request reprint Not pitch perfect: sensory contributions to affective communication impairment in schizophrenia
    David I Leitman
    Department of Psychiatry Neuropsychiatry Program, Brain Behavior Laboratory, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4283, USA
    Biol Psychiatry 70:611-8. 2011
    ..The neural correlates of this dysfunction are unclear. Prior study has suggested that schizophrenia vocal affect perception deficits stem from an inability to use acoustic cues, notably pitch, in decoding emotion...
  9. pmc Alterations of fronto-temporal connectivity during word encoding in schizophrenia
    Daniel H Wolf
    University of Pennsylvania, Department of Psychiatry, Philadelphia, PA 19104, USA
    Psychiatry Res 154:221-32. 2007
    ..The results suggest that reduced temporal-DLPFC connectivity in schizophrenia could underlie encoding deficits, and increased temporal-VLPFC connectivity may represent an ineffective compensatory effort...
  10. ncbi request reprint Prognostic variables at intake and long-term level of function in schizophrenia
    Steven J Siegel
    Division of Neuropsychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Psychiatry 163:433-41. 2006
    ..This study assessed the relationship between symptoms and cognitive measures at intake and functional outcome 2-8 years later (average 3 years) in first-episode and previously treated schizophrenia patients...
  11. ncbi request reprint Levels-of-processing effect on word recognition in schizophrenia
    J Daniel Ragland
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Biol Psychiatry 54:1154-61. 2003
    ..By requiring participants to classify and encode words on either a shallow (e.g., uppercase/lowercase) or deep level (e.g., concrete/abstract), the levels-of-processing paradigm eliminates the need to generate organizational strategies...
  12. ncbi request reprint Organization of semantic category exemplars in schizophrenia
    Stephen T Moelter
    University of the Sciences in Philadelphia, 600 South 43rd Street, Philadelphia, PA 19104, USA
    Schizophr Res 78:209-17. 2005
    ..Results suggest that performance differences on semantic tasks with limited retrieval demands in schizophrenia relate to difficulties utilizing higher-order categorization strategies...
  13. pmc Flat affect in schizophrenia: relation to emotion processing and neurocognitive measures
    Raquel E Gur
    Department of Psychiatry, Neuropsychiatry Division, Schizophrenia Center, University of Pennsylvania, USA
    Schizophr Bull 32:279-87. 2006
    ..However, the 2 patient groups did not differ in the neurocognitive profile except for verbal memory. We conclude that flat affect is an important clinical feature of schizophrenia that exacerbates the course of illness...
  14. ncbi request reprint Neurocognitive performance and clinical changes in olanzapine-treated patients with schizophrenia
    Raquel E Gur
    Schizophrenia Research Center, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 28:2029-36. 2003
    ..These results suggest that some effects of olanzapine may impact both symptoms and cognitive performance...
  15. ncbi request reprint Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia
    Raquel E Gur
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Am J Psychiatry 164:813-9. 2007
    ..The purpose of this article was to examine computerized neurocognitive measures as candidate endophenotypic markers of liability for schizophrenia in a genetically informative cohort...
  16. ncbi request reprint Hemodynamic responses in neural circuitries for detection of visual target and novelty: An event-related fMRI study
    Ruben C Gur
    Department of Psychiatry, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Hum Brain Mapp 28:263-74. 2007
    ..Age was associated with reduced peak HRF in left frontal region. Thus, indices of the HRF can be used to better understand the relationship between hemodynamic changes and performance and can be sensitive to individual differences...
  17. doi request reprint Project among African-Americans to explore risks for schizophrenia (PAARTNERS): evidence for impairment and heritability of neurocognitive functioning in families of schizophrenia patients
    Monica E Calkins
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Psychiatry 167:459-72. 2010
    ....
  18. ncbi request reprint Images of desire: food-craving activation during fMRI
    Marcia Levin Pelchat
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Neuroimage 23:1486-93. 2004
    ..Craving-related changes in fMRI signal were identified in the hippocampus, insula, and caudate, three areas reported to be involved in drug craving. Thus, this work supports the common substrate hypothesis for food and drug cravings...
  19. ncbi request reprint An fMRI study of facial emotion processing in patients with schizophrenia
    Raquel E Gur
    Section of Neuropsychiatry, Department of Psychiatry, Gates Bldg 10th Floor, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104 4283, USA
    Am J Psychiatry 159:1992-9. 2002
    ..The authors evaluated cerebral blood flow response in schizophrenia patients during facial emotion processing to test the hypothesis of diminished limbic activation related to emotional relevance of facial stimuli...
  20. ncbi request reprint Face recognition memory deficits and visual object memory performance in patients with schizophrenia and their relatives
    Monica E Calkins
    University of Pennsylvania School of Medicine, 10 Gates, 3400 Spruce St, Philadelphia, PA 19104, USA
    Am J Psychiatry 162:1963-6. 2005
    ..Biological relatives of patients have similar deficits, suggesting genetic susceptibility. Because the impairment may reflect generalized object memory deficits, the authors evaluated both face and visual object recognition...
  21. ncbi request reprint A comparison of cognitive structure in schizophrenia patients and healthy controls using confirmatory factor analysis
    Dwight Dickinson
    Department of Psychiatry, University of Maryland School of Medicine, BT MIRECC, Baltimore, 21201, USA
    Schizophr Res 85:20-9. 2006
    ..Cognitive ability, as reflected in test performance, appears to be more unitary in schizophrenia than in healthy subjects. This finding may have measurement and treatment implications...
  22. pmc Clinical, functional, and intertask correlations of measures developed by the Cognitive Neuroscience Test Reliability and Clinical Applications for Schizophrenia Consortium
    James M Gold
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD 21228, USA
    Schizophr Bull 38:144-52. 2012
    ..These results suggest that the CNTRACS tasks measure discrete cognitive abilities, some of which relate to aspects of functional capacity/outcome in schizophrenia...
  23. pmc "It's Not What You Say, But How You Say it": A Reciprocal Temporo-frontal Network for Affective Prosody
    David I Leitman
    Department of Psychiatry Neuropsychiatry Program, Brain Behavior Laboratory, University of Pennsylvania School of Medicine Philadelphia, PA, USA
    Front Hum Neurosci 4:19. 2010
    ..Auditory regions may thus integrate acoustic information with amygdala input to form emotion-specific representations, which are evaluated within inferior frontal regions...
  24. ncbi request reprint Neuropsychological profiles delineate distinct profiles of schizophrenia, an interaction between memory and executive function, and uneven distribution of clinical subtypes
    S Kristian Hill
    Brain Behavior Laboratory, Department of Psychiatry, University of Pennsylvania School of Medicine, Pennsylvania, USA
    J Clin Exp Neuropsychol 24:765-80. 2002
    ..This suggests greater correspondence than previously postulated between systems responsible for clinical symptomatology and those moderating neurocognitive dysfunction...
  25. ncbi request reprint Normative data for the symbol cancellation test in young healthy adults
    Natasha Lowery
    Brain Behavior Laboratory, Department of Psychiatry, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Appl Neuropsychol 11:218-21. 2004
    ..In addition, a relation likely exists between SCT performance and age and education, but a larger sample seems warranted to reliably model the pattern...
  26. ncbi request reprint The Penn Conditional Exclusion Test: a new measure of executive-function with alternate forms of repeat administration
    Matthew M Kurtz
    Department of Psychiatry, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
    Arch Clin Neuropsychol 19:191-201. 2004
    ..Divergent validity was established through low, nonsignificant correlations between the PCET and measures of facial emotion recognition, word and face memory, visuospatial function, and verbal reasoning...
  27. pmc Regional differences in the coupling between resting cerebral blood flow and metabolism may indicate action preparedness as a default state
    Ruben C Gur
    Section of Neuropsychiatry, Department of Psychiatry and the Philadelphia Veterans Administration Medical Center, University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    Cereb Cortex 19:375-82. 2009
    ..Whether greater left hemispheric hyperperfusion reflects lateral dominance needs further examination...
  28. ncbi request reprint The effects of geometric distortion correction on motion realignment in fMRI
    Mark A Elliott
    Department of Radiology, University of Pennsylvania, B1 Stellar Chance Labs, Philadelphia, PA 19104, USA
    Acad Radiol 11:1005-10. 2004
    ..This masking, when applied to subsequent images in the fMRI time series, can clip the effects of motion, resulting in inaccurate estimation and correction of motion-based changes in the images...
  29. ncbi request reprint Beyond hypofrontality: a quantitative meta-analysis of functional neuroimaging studies of working memory in schizophrenia
    David C Glahn
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Hum Brain Mapp 25:60-9. 2005
    ....
  30. pmc The cognitive neuroscience of memory function and dysfunction in schizophrenia
    Charan Ranganath
    Center for Neuroscience and Department of Psychology, University of California at Davis, Davis, CA 95618, USA
    Biol Psychiatry 64:18-25. 2008
    ..A brief summary of research on episodic memory in schizophrenia is presented to provide a context for investigating item-specific and relational memory processes. Candidate brain regions are also discussed...
  31. doi request reprint Association of dorsolateral prefrontal cortex dysfunction with disrupted coordinated brain activity in schizophrenia: relationship with impaired cognition, behavioral disorganization, and global function
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California, Davis, Sacramento, Calif 95817, USA
    Am J Psychiatry 165:1006-14. 2008
    ....
  32. ncbi request reprint Project among African-Americans to explore risks for schizophrenia (PAARTNERS): recruitment and assessment methods
    Muktar H Aliyu
    Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL 35294 2041, and Duke University Medical Center John Umstead Hospital, Butner, NC, United States
    Schizophr Res 87:32-44. 2006
    ..This novel integration of diagnostic, neurocognitive and genetic data will also generate valuable information for future phenotypic and genetic studies of schizophrenia...
  33. ncbi request reprint Symptoms versus neurocognitive test performance as predictors of psychosocial status in schizophrenia: a 1- and 4-year prospective study
    Matthew M Kurtz
    Schizophrenia Rehabilitation Program, Neuropsychiatry Research Center, Institute of Living, 200 Retreat Avenue, Hartford, CT 06106, USA
    Schizophr Bull 31:167-74. 2005
    ..The significance of these findings for the development and assessment of novel treatment interventions for schizophrenia is discussed...
  34. ncbi request reprint Sex differences in clustering and switching in verbal fluency tasks
    Elisabeth M Weiss
    Department of General Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    J Int Neuropsychol Soc 12:502-9. 2006
    ..In the current study, women adopted a more successful strategy of balancing clustering and switching in the phonemic fluency task...