Affiliation: University of Washington
- Biological markers and diagnostic accuracy in the genetics of posttraumatic stress disorderA Radant
Veterans Affairs Northwest Network Mental Illness Research, Education and Clinical Center MIRECC, VA Puget Sound 116, 1660 S Columbian Way, Seattle, WA 98108, USA
Psychiatry Res 102:203-15. 2001..However, the capacity of these traits to distinguish PTSD from non-PTSD patients and their familial pattern must be better defined before they can be employed in genetic studies...
- Successful multi-site measurement of antisaccade performance deficits in schizophreniaAllen D Radant
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States
Schizophr Res 89:320-9. 2007..These results confirm previous findings of antisaccade deficits in schizophrenia subjects and support the use of the antisaccade task as a potential schizophrenia endophenotype in multi-site genetic studies...
- Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS studyAllen D Radant
Department of Psychiatry and Behavioral Sciences, University of Washington and Department of Veteran Affairs, VISN 20, Mental Illness Research, Education, and Clinical Center, Seattle, Washington 98108, USA
Psychophysiology 47:846-56. 2010..Given the significant heritability of antisaccade performance, the effects of a genetic polymorphism is one possible explanation of our results...
- Reduced benzodiazepine sensitivity in patients with panic disorder: comparison with patients with obsessive-compulsive disorder and normal subjectsP Roy-Byrne
Department of Psychiatry, Tufts University, Boston, USA
Am J Psychiatry 153:1444-9. 1996....
- Admixture analysis of smooth pursuit eye movements in probands with schizophrenia and their relatives suggests gain and leading saccades are potential endophenotypesRandal G Ross
Department of Psychiatry, Denver Veterans Administration Medical Center, Colorado, USA
Psychophysiology 39:809-19. 2002..Relatives of childhood-onset and adult-onset probands had similar impairments. Gain and frequency of leading saccades may be genetic endophenotypes in childhood-onset and adult-onset schizophrenia...
- Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measuresBruce I Turetsky
Department of Psychiatry, 10th Floor, Gates Building, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
Schizophr Bull 33:69-94. 2007..We conclude with a discussion of the few studies thus far that have employed a multivariate approach with these candidates...
- Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophreniaTiffany A Greenwood
Department of Psychiatry, University of California San Diego, La Jolla, USA
Arch Gen Psychiatry 64:1242-50. 2007..Exploration of the genetic architecture of specific endophenotypes may be a powerful strategy for understanding the genetic basis of schizophrenia...
- The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaborationMonica E Calkins
Neuropsychiatry Section, Department of Psychiatry, University of Pennsylvania, 10 Gates, 3400 Spruce St, Philadelphia, PA 19104, USA
Schizophr Bull 33:33-48. 2007..The purpose of this article is to provide a description of the COGS structure and methods, including participant recruitment and assessment...
- Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of SchizophreniaNeal R Swerdlow
Department of Psychiatry, University of California San Diego, San Diego, California, USA
Schizophr Res 92:237-51. 2007..Genetic studies now often employ multiple, geographically dispersed test sites to accommodate the need for large and complex study samples. Here, we assessed the feasibility of using PPI in multi-site studies...