J Raber

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Passive avoidance learning and memory of 56Fe sham-irradiated and irradiated human apoE transgenic mice
    L Villasana
    Department of Behavioral Neuroscience, ONPRC, Oregon Health and Science University, Portland, Oregon 97239, USA
    Radiats Biol Radioecol 48:167-70. 2008
  2. pmc Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females
    J Raber
    Gladstone Institute of Neurological Disease, University of California, San Francisco, CA 94141 9100, USA
    Proc Natl Acad Sci U S A 95:10914-9. 1998
  3. ncbi request reprint Hypothalamic-pituitary-adrenal dysfunction in Apoe(-/-) mice: possible role in behavioral and metabolic alterations
    J Raber
    Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141 9100, USA
    J Neurosci 20:2064-71. 2000
  4. ncbi request reprint Apolipoprotein E and cognitive performance
    J Raber
    Gladstone Institute of Neurological Disease, University of California, San Francisco 94141 9100, USA
    Nature 404:352-4. 2000
  5. ncbi request reprint Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
    S J Smith
    Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California, USA
    Nat Genet 25:87-90. 2000
  6. ncbi request reprint Corticotropin-releasing factor and adrenocorticotrophic hormone as potential central mediators of OB effects
    J Raber
    Gladstone Molecular Neurobiology Program and the Department of Neurology, University of California, San Francisco, California 94141 9100, USA
    J Biol Chem 272:15057-60. 1997
  7. ncbi request reprint Effects of sex and APOE epsilon4 on object recognition and spatial navigation in the elderly
    F Berteau-Pavy
    Department of Behavioral Neuroscience, L470, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA
    Neuroscience 147:6-17. 2007
  8. ncbi request reprint Sex-differences in age-related cognitive decline in C57BL/6J mice associated with increased brain microtubule-associated protein 2 and synaptophysin immunoreactivity
    T S Benice
    Department of Behavioral Neuroscience, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, 97239, USA
    Neuroscience 137:413-23. 2006
  9. ncbi request reprint Role of H(3) receptor-mediated signaling in cognition
    G Bongers
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97201, USA
    Inflamm Res 53:S51-2. 2004
  10. ncbi request reprint Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase
    J Raber
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA
    Virology 226:362-73. 1996

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Passive avoidance learning and memory of 56Fe sham-irradiated and irradiated human apoE transgenic mice
    L Villasana
    Department of Behavioral Neuroscience, ONPRC, Oregon Health and Science University, Portland, Oregon 97239, USA
    Radiats Biol Radioecol 48:167-70. 2008
    ....
  2. pmc Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females
    J Raber
    Gladstone Institute of Neurological Disease, University of California, San Francisco, CA 94141 9100, USA
    Proc Natl Acad Sci U S A 95:10914-9. 1998
    ..These results could be pertinent to cognitive impairments observed in human APOE epsilon4 carriers. NSE-apoE mice and similar models may facilitate the preclinical assessment of treatments for apoE-related cognitive deficits...
  3. ncbi request reprint Hypothalamic-pituitary-adrenal dysfunction in Apoe(-/-) mice: possible role in behavioral and metabolic alterations
    J Raber
    Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141 9100, USA
    J Neurosci 20:2064-71. 2000
    ..These results support a key role for apoE in the tonic inhibition of steroidogenesis and HPA axis activity and have important implications for the behavioral analysis of Apoe(-/-) mice...
  4. ncbi request reprint Apolipoprotein E and cognitive performance
    J Raber
    Gladstone Institute of Neurological Disease, University of California, San Francisco 94141 9100, USA
    Nature 404:352-4. 2000
  5. ncbi request reprint Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
    S J Smith
    Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California, USA
    Nat Genet 25:87-90. 2000
    ..Our findings indicate that multiple mechanisms exist for triglyceride synthesis and suggest that the selective inhibition of Dgat-mediated triglyceride synthesis may be useful for treating obesity...
  6. ncbi request reprint Corticotropin-releasing factor and adrenocorticotrophic hormone as potential central mediators of OB effects
    J Raber
    Gladstone Molecular Neurobiology Program and the Department of Neurology, University of California, San Francisco, California 94141 9100, USA
    J Biol Chem 272:15057-60. 1997
    ..An imbalance between the effects of OB on corticotropin-releasing factor release from the hypothalamus and on adrenocorticotrophic hormone release from the pituitary could contribute to obesity...
  7. ncbi request reprint Effects of sex and APOE epsilon4 on object recognition and spatial navigation in the elderly
    F Berteau-Pavy
    Department of Behavioral Neuroscience, L470, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA
    Neuroscience 147:6-17. 2007
    ..In men, salivary cortisol levels correlated with object recognition. These results show that object recognition and spatial navigation tests are useful to assess cognitive function in the elderly...
  8. ncbi request reprint Sex-differences in age-related cognitive decline in C57BL/6J mice associated with increased brain microtubule-associated protein 2 and synaptophysin immunoreactivity
    T S Benice
    Department of Behavioral Neuroscience, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, 97239, USA
    Neuroscience 137:413-23. 2006
    ..Elevated levels of microtubule-associated protein 2 and synaptophysin may constitute a compensatory response to age-related functional decline in mice...
  9. ncbi request reprint Role of H(3) receptor-mediated signaling in cognition
    G Bongers
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97201, USA
    Inflamm Res 53:S51-2. 2004
  10. ncbi request reprint Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase
    J Raber
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA
    Virology 226:362-73. 1996
    ..These findings demonstrate that CNS expression of a viral envelope protein can activate the HPA axis and thereby alter peripheral levels of immunomodulatory hormones...
  11. pmc Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli
    X Xu
    Gladstone Molecular Neurobiology Program and Department of Neurology, University of California, San Francisco, CA 94141, USA
    Proc Natl Acad Sci U S A 94:12655-60. 1997
    ..In contrast, the high baseline activity of JNK in the brain and the activation of the JNK cascade by environmental stimuli suggest that this kinase may play an important physiological role in neuronal function...
  12. ncbi request reprint Nitric oxide is not involved in the control of vasopressin release during acute forced swimming in rats
    M Engelmann
    Institut für Medizinische Neurobiologie, Otto von Guericke Universitat Magdeburg, Magdeburg, Germany
    Amino Acids 26:37-43. 2004
    ..Increased nNOS mRNA in the SON after forced swimming and the increase in AVP release in the presence of exogenous NO under forced swimming points to a possible role of NO in the regulation of the HNS under repeated stressor exposure...