ROBERT QUIVEY

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint The putative autolysin regulator LytR in Streptococcus mutans plays a role in cell division and is growth-phase regulated
    Christa H Chatfield
    Center for Oral Biology, University of Rochester, Rochester, NY 14642, USA
    Microbiology 151:625-31. 2005
  2. pmc Raman microspectroscopy for species identification and mapping within bacterial biofilms
    Brooke D Beier
    The Institute of Optics, University of Rochester, 275 Hutchison Rd, Rochester, NY 14627, USA
    AMB Express 2:35. 2012
  3. pmc The branched-chain amino acid aminotransferase encoded by ilvE is involved in acid tolerance in Streptococcus mutans
    Brendaliz Santiago
    Center for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Bacteriol 194:2010-9. 2012
  4. pmc Mutation of the NADH oxidase gene (nox) reveals an overlap of the oxygen- and acid-mediated stress responses in Streptococcus mutans
    Adam M Derr
    Center for Oral Biology and Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA
    Appl Environ Microbiol 78:1215-27. 2012
  5. ncbi request reprint Shifts in membrane fatty acid profiles associated with acid adaptation of Streptococcus mutans
    R G Quivey
    Center for Oral Biology, University of Rochester, New York 14642, USA
    FEMS Microbiol Lett 189:89-92. 2000
  6. ncbi request reprint Genetics of acid adaptation in oral streptococci
    R G Quivey
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Crit Rev Oral Biol Med 12:301-14. 2001
  7. pmc Influence of apigenin on gtf gene expression in Streptococcus mutans UA159
    Hyun Koo
    Eastman Department of Dentistry and Center for Oral Biology, University of Rochester Medical Center, 625 Elmwood Ave, Box 683, Rochester, NY 14620, USA
    Antimicrob Agents Chemother 50:542-6. 2006
  8. pmc The F-ATPase operon promoter of Streptococcus mutans is transcriptionally regulated in response to external pH
    Wendi L Kuhnert
    Center for Oral Biology, Box 611, 601 Elmwood Ave, Rochester, NY 14642, USA
    J Bacteriol 186:8524-8. 2004
  9. pmc Two Spx proteins modulate stress tolerance, survival, and virulence in Streptococcus mutans
    Jessica K Kajfasz
    Center for Oral Biology, University of Rochester Medical Center, Box 611, 601 Elmwood Ave, Rochester, NY 14642, USA
    J Bacteriol 192:2546-56. 2010
  10. pmc Shifts in the membrane fatty acid profile of Streptococcus mutans enhance survival in acidic environments
    Elizabeth M Fozo
    Department of Microbiology and Immunology, University of Rochester, Rochester, New York 14642, USA
    Appl Environ Microbiol 70:929-36. 2004

Collaborators

  • Hyun Koo
  • JOSE A LEMOS
  • Robert E Marquis
  • Elizabeth M Fozo
  • Roberta C Faustoferri
  • Jessica K Kajfasz
  • Adam M Derr
  • Qingyuan Zhu
  • Andrew J Berger
  • Brendaliz Santiago
  • Brooke D Beier
  • Isamar Rivera-Ramos
  • Jacqueline Abranches
  • Alaina R Martinez
  • Christa H Chatfield
  • Wendi L Kuhnert
  • Matthew Macgilvray
  • Matthew J Betzenhauser
  • Kaisha Gonzalez
  • Pedro L Rosalen
  • Kathy Scott-Anne
  • Kellie Weiss
  • Kristina Hahn
  • Guolu Zheng

Detail Information

Publications16

  1. ncbi request reprint The putative autolysin regulator LytR in Streptococcus mutans plays a role in cell division and is growth-phase regulated
    Christa H Chatfield
    Center for Oral Biology, University of Rochester, Rochester, NY 14642, USA
    Microbiology 151:625-31. 2005
    ..No defect in cell-to-surface adherence or biofilm growth was seen in the LytR mutant. However, a connection between cell growth phase and transcription of lytR was found...
  2. pmc Raman microspectroscopy for species identification and mapping within bacterial biofilms
    Brooke D Beier
    The Institute of Optics, University of Rochester, 275 Hutchison Rd, Rochester, NY 14627, USA
    AMB Express 2:35. 2012
    ..We then used the algorithm successfully both to detect the presence of two species in mixed biofilms and to create spatial maps within these biofilms...
  3. pmc The branched-chain amino acid aminotransferase encoded by ilvE is involved in acid tolerance in Streptococcus mutans
    Brendaliz Santiago
    Center for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Bacteriol 194:2010-9. 2012
    ..Collectively, the results of this investigation show that amino acid metabolism is a component of the acid-adaptive repertoire of S. mutans...
  4. pmc Mutation of the NADH oxidase gene (nox) reveals an overlap of the oxygen- and acid-mediated stress responses in Streptococcus mutans
    Adam M Derr
    Center for Oral Biology and Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA
    Appl Environ Microbiol 78:1215-27. 2012
    ..Appl. Environ. Microbiol. 70:929-936, 2004). The heightened ability of the nox strain to survive acidic and oxidative environmental stress suggests a multifaceted response system that is partially dependent on oxygen metabolites...
  5. ncbi request reprint Shifts in membrane fatty acid profiles associated with acid adaptation of Streptococcus mutans
    R G Quivey
    Center for Oral Biology, University of Rochester, New York 14642, USA
    FEMS Microbiol Lett 189:89-92. 2000
    ..2 and 0.3. Cyclopropane fatty acids were not detected. Streptococcus sobrinus 6715, which is known to have minimal acid-adaptive capacity, showed only minimal change in membrane fatty acids...
  6. ncbi request reprint Genetics of acid adaptation in oral streptococci
    R G Quivey
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Crit Rev Oral Biol Med 12:301-14. 2001
    ....
  7. pmc Influence of apigenin on gtf gene expression in Streptococcus mutans UA159
    Hyun Koo
    Eastman Department of Dentistry and Center for Oral Biology, University of Rochester Medical Center, 625 Elmwood Ave, Box 683, Rochester, NY 14620, USA
    Antimicrob Agents Chemother 50:542-6. 2006
    ..The data show that apigenin modulates the genetic expression of virulence factors in S. mutans...
  8. pmc The F-ATPase operon promoter of Streptococcus mutans is transcriptionally regulated in response to external pH
    Wendi L Kuhnert
    Center for Oral Biology, Box 611, 601 Elmwood Ave, Rochester, NY 14642, USA
    J Bacteriol 186:8524-8. 2004
    ..Fusions of the F-ATPase promoter to chloramphenicol acetyltransferase indicated that pH-dependent expression is still observed with a short promoter that contains a domain conserved between streptococcal ATPase operons...
  9. pmc Two Spx proteins modulate stress tolerance, survival, and virulence in Streptococcus mutans
    Jessica K Kajfasz
    Center for Oral Biology, University of Rochester Medical Center, Box 611, 601 Elmwood Ave, Rochester, NY 14642, USA
    J Bacteriol 192:2546-56. 2010
    ..Given the high degree of conservation between Spx proteins of low-GC gram-positive bacteria, these results are likely to have broad implications...
  10. pmc Shifts in the membrane fatty acid profile of Streptococcus mutans enhance survival in acidic environments
    Elizabeth M Fozo
    Department of Microbiology and Immunology, University of Rochester, Rochester, New York 14642, USA
    Appl Environ Microbiol 70:929-36. 2004
    ..Results presented here indicate that membrane fatty acid redistribution is important for low pH survival and, as such, is a component of the S. mutans acid-adaptation arsenal...
  11. pmc Role of Clp proteins in expression of virulence properties of Streptococcus mutans
    Jessica K Kajfasz
    Center for Oral Biology, University of Rochester Medical Center, NY 14642, USA
    J Bacteriol 191:2060-8. 2009
    ..mutans and indicates that the underlying mechanisms by which ClpXP affect virulence traits are associated with the accumulation of two Spx orthologues...
  12. pmc Raman spectroscopic measurement of relative concentrations in mixtures of oral bacteria
    Qingyuan Zhu
    The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
    Appl Spectrosc 61:1233-7. 2007
    ..07. These results suggest that near-infrared Raman spectroscopy is potentially useful in quantification of microbial mixtures in general and oral plaques in particular...
  13. pmc Role of unsaturated fatty acid biosynthesis in virulence of Streptococcus mutans
    Elizabeth M Fozo
    Department of Microbiology and Immunology, Center for Oral Biology, Rochester, NY 14642, USA
    Infect Immun 75:1537-9. 2007
    ..In this study, the strain was shown to be poorly transmissible from host to host. Animals directly infected with the fabM strain exhibited fewer and less severe carious lesions than those observed in the wild-type strain...
  14. pmc The fabM gene product of Streptococcus mutans is responsible for the synthesis of monounsaturated fatty acids and is necessary for survival at low pH
    Elizabeth M Fozo
    Department of Microbiology and Immunology, University of Rochester, Rochester, New York 14642, USA
    J Bacteriol 186:4152-8. 2004
    ..The results suggest that altered membrane composition can significantly affect the acid survival capabilities, as well as several enzymatic activities, of S. mutans...
  15. pmc Smx nuclease is the major, low-pH-inducible apurinic/apyrimidinic endonuclease in Streptococcus mutans
    Roberta C Faustoferri
    Center for Oral Biology, Aab Institute for Biomedical Sciences, 601 Elmwood Ave, Rochester, NY 14642, USA
    J Bacteriol 187:2705-14. 2005
    ..Smx is likely the primary, if not the sole, AP endonuclease induced during growth at low pH values...
  16. ncbi request reprint Measurement of bacterial concentration fractions in polymicrobial mixtures by Raman microspectroscopy
    Qingyuan Zhu
    University of Rochester, Department of Electrical Engineering and The Institute of Optics, Rochester, NY 14627, USA
    J Biomed Opt 9:1182-6. 2004
    ..mutans. Samples with and without salivary proteins are predicted with equal accuracy. This result shows the potential of Raman spectroscopy for analyzing mixed populations of bacteria, such as those that occur in oral plaques...

Research Grants19

  1. Low pH-mediated membrane biosynthesis in S. mutans.
    Robert G Quivey; Fiscal Year: 2010
    ..mutans membranes relate to fluidity;5) finally, we will determine how S. mutans uses its fab genes to respond to membrane disrupting agents such as cerulenin and tt-farnesol. ..
  2. Fitness profiling of the Streptococcus mutans genome
    ROBERT QUIVEY; Fiscal Year: 2009
    ..mutans uses to cause disease in humans. ..
  3. Low pH-mediated membrane biosynthesis in S. mutans.
    ROBERT QUIVEY; Fiscal Year: 2009
    ..mutans membranes relate to fluidity; 5) finally, we will determine how S. mutans uses its fab genes to respond to membrane disrupting agents such as cerulenin and tt-farnesol. ..
  4. Low pH-mediated membrane biosynthesis in S. mutans.
    ROBERT QUIVEY; Fiscal Year: 2007
    ..mutans membranes relate to fluidity; 5) finally, we will determine how S. mutans uses its fab genes to respond to membrane disrupting agents such as cerulenin and tt-farnesol. ..
  5. Fitness profiling of the Streptococcus mutans genome
    ROBERT QUIVEY; Fiscal Year: 2007
    ..mutans uses to cause disease in humans. ..
  6. LOW PH INDUCIBLE DNA REPAIR IN STREPTOCOCCUS MUTANS
    ROBERT QUIVEY; Fiscal Year: 2005
    ..mutans exonuclease, including a description of the genetic elements that participate in regulating synthesis of the enzyme and the protein(s) that function to regulate transcription of the exonuclease gene. ..
  7. VIRULENCE AND GENETIC RECOMBINATION OF ORAL STREPTOCOCCI
    ROBERT QUIVEY; Fiscal Year: 1999
    ..Lastly, we will obtain insight into the primary metabolic goal of a bacterium, that is, the maintenance and replication of its genetic stock under varying environmental conditions. ..
  8. Fitness profiling of the Streptococcus mutans genome
    Robert G Quivey; Fiscal Year: 2010
    ..mutans uses to cause disease in humans. ..