Research Topics
| MARK S QUIGGSummaryAffiliation: University of Virginia Country: USA Publications
Research Grants
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Detail Information
Publications
Risks of history of diabetes mellitus, hypertension, and other factors related to radiation-induced changes following Gamma Knife surgery for cerebral arteriovenous malformationsMark Quigg
Department of Neurology, University of Virginia Health System, Charlottesville, Virginia 22908, USA
J Neurosurg 117:144-9. 2012..The goal of the present study was to determine associations between DM or hypertension and other factors in the development of radiotoxicity, as measured by radiation-induced changes (RICs) on MR images following radiosurgery for AVM...
Radiosurgery for epilepsy: clinical experience and potential antiepileptic mechanismsMark Quigg
Department of Neurology, University of Virginia, Charlottesville, Virginia 22908, USA
Epilepsia 53:7-15. 2012..An ongoing trial that directly compares efficacy, morbidities, and cost of radiosurgery versus open surgery for mesial temporal lobe epilepsy is underway...
Clinical findings of the phakomatoses: von Hippel-Lindau diseaseMark Quigg
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
Neurology 66:E33-4. 2006- Conduction aphasia as a function of the dominant posterior perisylvian cortex. Report of two casesMark Quigg
Department of Neurology and Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
J Neurosurg 104:845-8. 2006..These cases demonstrate a localization of language repetition to the posterior perisylvian cortex. Brain mapping of this region should include assessment of verbal repetition to avoid potential deficits resembling conduction aphasia... - Clinical findings of the phakomatoses: hypomelanosis of ItoMark Quigg
Department of Neurology, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
Neurology 66:E45. 2006 - Interictal and postictal circadian and ultradian luteinizing hormone secretion in men with temporal lobe epilepsyMark Quigg
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
Epilepsia 47:1452-9. 2006..Our objective is to determine if epilepsy or seizures disrupt normal circadian fluctuations of LH as well as circadian organization of ultradian bursts of LH... - Acute insomnia following surgery of the ventralis intermedius nucleus of the thalamus for tremorMark Quigg
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
J Clin Sleep Med 3:58-9. 2007..This complication underscores the role of thalamic regulation on initiation and maintenance of sleep... - Circalunar and ultralunar periodicities in women with partial seizuresMark Quigg
Department of Neurology, University of Virginia, Charlottesville, Virginia 22908, USA
Epilepsia 49:1081-5. 2008..In the present study, we determined seizure periodicity according to a "menstrual clock" provided by a common phase marker of the onset of menses... - Stereotactic radiosurgery for treatment of epilepsyMark Quigg
Department of Neurology, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA
Arch Neurol 65:177-83. 2008..Further studies will be required to determine whether efficacy attains that of traditional surgery while offering a noninvasive technique with potentially lower morbidity... - Engineering aspects of the quantified amplitude-integrated electroencephalogram in neonatal cerebral monitoringMark Quigg
Department of Neurology and daggerSchool of Engineering and Applied Science, University of Virginia, Charlottesville, VA 22908, USA
J Clin Neurophysiol 26:145-9. 2009..Comparisons of aEEG must carefully account for differences in machines, interelectrode distances, and electrode locations. Q-aEEG may offer a rigorous method of evaluating hypoxic-ischemic encephalopathy... - Laterality and location influence catamenial seizure expression in women with partial epilepsyM Quigg
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
Neurology 73:223-7. 2009..The location and laterality of the epileptic lesion as well as patient age may affect periodicity... - Interrater reliability to assure valid content in peer review of CME-accredited presentationsMark Quigg
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
J Contin Educ Health Prof 29:242-5. 2009.... - Neuropsychological outcomes after Gamma Knife radiosurgery for mesial temporal lobe epilepsy: a prospective multicenter studyMark Quigg
Department of Neurology, University of Virginia, Charlottesville, Virginia 22908, USA
Epilepsia 52:909-16. 2011..To assess outcomes of language, verbal memory, cognitive efficiency and mental flexibility, mood, and quality of life (QOL) in a prospective, multicenter pilot study of Gamma Knife radiosurgery (RS) for mesial temporal lobe epilepsy (MTLE)... - Clinical findings of the phakomatoses: neurofibromatosisMark Quigg
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
Neurology 66:E23-4. 2006 - Clinical findings of the phakomatoses: Sturge-Weber syndromeMark Quigg
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
Neurology 66:E17-8. 2006 - Conduction aphasia elicited by stimulation of the left posterior superior temporal gyrusM Quigg
Department of Neurology, University of Virginia, Charlottesville 22908, USA
J Neurol Neurosurg Psychiatry 66:393-6. 1999..Disruption of fascicular tracts that connect Wernicke's to Broca's areas is the classic mechanism of conduction aphasia. Later work has emphasised cortical mechanisms... - Hypothalamic neuronal loss and altered circadian rhythm of temperature in a rat model of mesial temporal lobe epilepsyM Quigg
Department of Neurology, University of Virginia, Charlottesville 22908, USA
Epilepsia 40:1688-96. 1999..We then wished to determine whether there was a structural basis for regulatory alterations... - Effects of circadian regulation and rest-activity state on spontaneous seizures in a rat model of limbic epilepsyM Quigg
Comprehensive Epilepsy Program, Department of Neurology, National Science Foundation Center for Biological Timing, University of Virginia, Charlottesville, Virginia 22908, USA
Epilepsia 41:502-9. 2000..Circadian regulation via the suprachiasmatic nuclei and rest-activity state may influence expression of limbic seizures... - Circadian rhythms: interactions with seizures and epilepsyM Quigg
NSF Center for Biological Timing, Department of Neurology, University of Virginia, Box 394, HSC, Charlottesville, VA 22908, USA
Epilepsy Res 42:43-55. 2000..Experimental designs should take into account time-of-day effects on seizure threshold and occurrence. Further work is required to determine what mechanisms account for daily variation in seizure susceptibility... - Seizures induce phase shifts of rat circadian rhythmsM Quigg
Comprehensive Epilepsy Program, Department of Neurology, University of Virginia, Box 394, Health Sciences Center, Charlottesville, VA 22908, USA
Brain Res 913:165-9. 2001..Epileptic seizures may alter neuroendocrinological cycles. Light pulses induce phase shifts in circadian rhythms. Using hippocampal-kindled rats to ensure maximal clinical expression, we determined if seizures likewise induce phase shifts... - Interictal and postictal alterations of pulsatile secretions of luteinizing hormone in temporal lobe epilepsy in menMark Quigg
Department of Neurology, Center for Biological Timing and Biomathematical Technology, University of Virginia, Charlottesville 22908, USA
Ann Neurol 51:559-66. 2002..Altered timing and regularity of neuroendocrine pulse patterns may underlie other disorders of homeostasis in mesial temporal lobe epilepsy... - Longitudinal distribution of hippocampal atrophy in mesial temporal lobe epilepsyM Quigg
Health Sciences Center, Department of Neurology, Charlottesville, VA 22908, USA
Epilepsy Res 27:101-10. 1997..We determined that overall volume loss in HS is diffuse, neither clearly favoring the head nor body-tail. Surgical outcome for MTLE is not related to the longitudinal distribution of atrophy revealed by volumetric MRI... - Clinical findings of the phakomatoses: tuberous sclerosisMark Quigg
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
Neurology 65:E22-3. 2005 - Depression in intractable partial epilepsy varies by laterality of focus and surgeryMark Quigg
Department of Neurology, F E Dreifuss Comprehensive Epilepsy Program, University of Virginia, Charlottesville, Virginia 22908, USA
Epilepsia 44:419-24. 2003..We reviewed the pre- and postsurgical psychological assessments and clinical courses of patients to identify those at highest risk for postsurgical mood disorders... - Bipolar deep brain stimulation permits routine EKG, EEG, and polysomnographyRobert C Frysinger
Department of Neurosurgery, University of Virginia, Charlottesville, VA, USA
Neurology 66:268-70. 2006..The authors find that monopolar, but not bipolar, stimulation produces significant artifact during EKG, EEG, and polysomnography... - The safety and utility of recombinant human bone morphogenetic protein-2 for cranial procedures in a nonhuman primate modelJason P Sheehan
Department of Neurological Surgery and Neurology, University of Virginia, Charlottesville, Virginia 22908, USA
J Neurosurg 98:125-30. 2003..The goal of this study was to evaluate the safety and efficacy of recombinant human bone morphogenetic protein 2 (rhBMP-2) in cranial applications... - Sixty day continuous use of subdermal wire electrodes for EEG monitoring during treatment of status epilepticusGabriel U Martz
FE Dreifuss Comprehensive Epilepsy Program, Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
Neurocrit Care 11:223-7. 2009..The technical difficulties of maintaining artifact-free, low impedance data collection are magnified by the ICU environment and prolonged duration of monitoring often required for these patients... - Characterization of synchronization in interacting groups of oscillators: application to seizuresIstvan Z Kiss
Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia, USA
Biophys J 94:1121-30. 2008.... - Stroboscopic artifact in digital video-EEGMark Quigg
Department of Neurology and the FE Dreifuss Comprehensive Epilepsy Program, University of Virginia, Charlottesville, Virginia 22908, USA
J Clin Neurophysiol 21:96-8. 2004..Stroboscopic aliasing is a DV-EEG specific artifact that can complicate accurate interpretation of photoparoxysmal responses... - Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsyRobert Fisher
Department of Neurology, Stanford University, Stanford, California 94305 5235, USA
Epilepsia 51:899-908. 2010..We report a multicenter, double-blind, randomized trial of bilateral stimulation of the anterior nuclei of the thalamus for localization-related epilepsy... - Standardized mental status testing for nonconvulsive status epilepticusDeanna Kirby
EEG/Evoked Potential Laboratory, Department of Neurology, University of Virginia Health System, Charlottesville, Virginia, USA
Am J Electroneurodiagnostic Technol 44:199-201. 2004
Research Grants
- CHRONOBIOLOGY OF PARTIAL EPILEPSYMark Quigg; Fiscal Year: 2002..In summary, these studies will provide insight into the chronoblological factors that facilitate partial seizure expression and may provide new perspectives into treatments for poorly controlled partial epilepsy. ..