Research Topics
| N PusterlaSummaryAffiliation: University of California Country: USA Publications
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Publications
Emerging outbreaks associated with equine coronavirus in adult horsesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Microbiol 162:228-31. 2013..The overall agreement between clinical status and PCR detection of ECoV was 91%. The study results suggest that ECoV is associated with self-limiting clinical and hematological abnormalities in adult horses...
Transmission of Lawsonia intracellularis to weanling foals using feces from experimentally infected rabbitsN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet J 195:241-3. 2013..intracellularis in their feces and all seroconverted. The results support the role of rabbits as asymptomatic amplifiers of L. intracellularis and their role as sources of infection for susceptible foals...
Further investigation of exposure to Lawsonia intracellularis in wild and feral animals captured on horse properties with equine proliferative enteropathyNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA Electronic address
Vet J 194:253-5. 2012..intracellularis. These animals may be an indicator of environmental exposure or may be actively involved in the transmission of L. intracellularis to foals by acting as a potential reservoir/amplifier host...
Prevalence of latent alpha-herpesviruses in Thoroughbred racing horsesNicola Pusterla
Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet J 193:579-82. 2012....
Lawsonia intracellularis-specific interferon γ gene expression by peripheral blood mononuclear cells in vaccinated and naturally infected foalsNicola Pusterla
Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet J 192:249-51. 2012..When IFN-γ gene transcription was compared between naturally infected and vaccinated foals, a significant difference (P<0.05) was observed only for day 0...
Efficacy of an avirulent live vaccine against Lawsonia intracellularis in the prevention of proliferative enteropathy in experimentally infected weanling foalsNicola Pusterla
Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, USA
Am J Vet Res 73:741-6. 2012..To determine the efficacy of an avirulent Lawsonia intracellularis vaccine in preventing proliferative enteropathy in weanling foals...
Acute hemoperitoneum in horses: a review of 19 cases (1992-2003)N Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Intern Med 19:344-7. 2005..In one horse, no origin of the bleeding could be determined during postmortem examination...
Real-time polymerase chain reaction: a novel molecular diagnostic tool for equine infectious diseasesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Intern Med 20:3-12. 2006..The novel real-time PCR strategy and clinical applications in equine infectious diseases will be the subject of this review...
Endogenous transplacental transmission of Neospora hughesi in naturally infected horsesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, California 95616, USA
J Parasitol 97:281-5. 2011..hughesi. Only 1 placenta collected in 2007 from the mare with the 2 congenitally infected foals tested PCR positive for N. hughesi. In conclusion, N. hughesi persisted in this population via endogenous transplacental infection...
Multicentric T-cell lymphosarcoma in an alpacaN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet J 171:181-5. 2006..Post mortem examination confirmed multicentric lymphosarcoma involving multiple organs. Immunophenotyping using cross reactive T- and B-cell antibodies characterized the tumour as a T-cell lymphosarcoma...
Acremonium strictum pulmonary infection in a horseNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, CA, USA
Vet Clin Pathol 34:413-6. 2005..To our knowledge, this is the first report of isolation of A strictum from the BAL fluid of a horse with interstitial pneumonia...
Surveillance programme for important equine infectious respiratory pathogens in the USAN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 169:12. 2011..There were 15 horses with double infections and one horse with a triple infection. The detection rate by PCR for the different pathogens varied with season and with the age, breed, sex and use of the animal...
Evaluation of the humoral immune response and fecal shedding in weanling foals following oral and intra-rectal administration of an avirulent live vaccine of Lawsonia intracellularisNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA
Vet J 182:458-62. 2009..Pre-medication with omeprazole prior to oral vaccination in group 1 foals led to an earlier and stronger detectable humoral response compared to non pre-medicated foals...
Initial clinical impressions of the U.C. Davis large animal lift and its use in recumbent equine patientsN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
Schweiz Arch Tierheilkd 148:161-6. 2006....
Prevalence of equine herpesvirus type 1 in trigeminal ganglia and submandibular lymph nodes of equids examined postmortemN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 167:376-8. 2010..Twelve trigeminal ganglia contained both latent neurotropic and non-neurotropic EHV-1. The prevalence and distribution of EHV-1 biovars among the study horses appeared to be influenced by their breed and the type of tissue tested...
Equine herpesvirus-1 myeloencephalopathy: a review of recent developmentsNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA
Vet J 180:279-89. 2009..This review concentrates on these and other selected, clinically relevant aspects of EHM...
Detection of Lawsonia intracellularis by real-time PCR in the feces of free-living animals from equine farms with documented occurrence of equine proliferative enteropathyNicola Pusterla
Department of Medicine and Epidemiology, University of California, Davis, California 95616, USA
J Wildl Dis 44:992-8. 2008..Because the fecal samples were collected at equine farms with confirmed cases of EPE, striped skunks, Virginian opossums, jackrabbits, and coyotes may act as potential sources of infection to susceptible weanlings...
Temporal detection of Lawsonia intracellularis using serology and real-time PCR in Thoroughbred horses residing on a farm endemic for equine proliferative enteropathyNicola Pusterla
Department of Medicine and Epidemiology, University of California, Davis, CA 95616, USA
Vet Microbiol 136:173-6. 2009..The serological results showed that mares residing on a farm known to be endemic for EPE are routinely exposed to L. intracellularis and that antibodies against L. intracellularis are passively transferred to foals...
Lawsonia intracellularis: humoral immune response and fecal shedding in weanling foals following intra-rectal administration of frozen-thawed or lyophilized avirulent live vaccineNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet J 186:110-2. 2010..intracellularis by real-time PCR. Both vaccine formulations administered intra-rectally in weanling foals were safe and led to similar onset and duration of fecal shedding and measurable serum IgG response against L. intracellularis...
Disseminated intravascular coagulation in a horse with Streptococcus equi subspecies zooepidemicus meningoencephalitis and interstitial pneumoniaNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA
J Vet Intern Med 21:344-7. 2007
Survey of the large-animal diplomates of the American College of Veterinary Internal Medicine regarding knowledge and clinical use of polymerase chain reaction: implications for veterinary educationNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA
J Vet Med Educ 33:605-11. 2006..Didactic training in veterinary curricula and during continuing-education opportunities continues to be necessary to produce veterinarians who have an understanding of the clinical applications of molecular diagnostics...
Use of quantitative real-time PCR for the detection of Salmonella spp. in fecal samples from horses at a veterinary teaching hospitalNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA
Vet J 186:252-5. 2010..The judicious use of such a RT-PCR method has the potential to reduce the risk of nosocomial infections such as salmonellosis through the provision of highly accurate and rapid pathogen detection...
Comparison of four methods to quantify Equid herpesvirus 1 load by real-time polymerase chain reaction in nasal secretions of experimentally and naturally infected horsesNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Diagn Invest 21:836-40. 2009....
Oral infection of weanling foals with an equine isolate of Lawsonia intracellularis, agent of equine proliferative enteropathyN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Intern Med 24:622-7. 2010..Equine proliferative enteropathy (EPE) is an emerging disease of weanling foals...
Molecular investigation of the viral kinetics of equine herpesvirus-1 in blood and nasal secretions of horses after corticosteroid-induced recrudescence of latent infectionN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA
J Vet Intern Med 24:1153-7. 2010..Recrudescence of latent equine herpesvirus 1 (EHV-1) with subsequent viral shedding via nasal secretions is a potential source of infection for susceptible horses and has been implicated in outbreaks occurring in closed populations...
Comparison of feces versus rectal swabs for the molecular detection of Lawsonia intracellularis in foals with equine proliferative enteropathyNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Diagn Invest 22:741-4. 2010..intracellularis increased from 76% and 79% for rectal swabs and feces, respectively, to 90%. Rectal swabs should be considered as an alternative sample type for EPE-suspected patients with decreased or no fecal output...
Fatal pulmonary hemorrhage associated with RTX toxin producing Actinobacillus equuli subspecies haemolyticus infection in an adult horseNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA
J Vet Diagn Invest 20:118-21. 2008..The presence of pneumonia associated with hemorrhagic pulmonary fluid and the culture of large numbers of hemolytic A. equuli should prompt the clinician to consider endothelial damage caused by bacterial toxins...
Digenetic trematodes, Acanthatrium sp. and Lecithodendrium sp., as vectors of Neorickettsia risticii, the agent of Potomac horse feverN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, California 95616, USA
J Helminthol 77:335-9. 2003..risticii. The data also suggest that bats and swallows not only act as a host for trematodes but also as a possible natural reservoir for N. risticii...
Evidence of the human granulocytic ehrlichiosis agent in Ixodes ricinus ticks in SwitzerlandN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, CH 8057 Zurich, Switzerland
J Clin Microbiol 37:1332-4. 1999..The occurrence of this agent in I. ricinus in Switzerland presents a potential danger of transmission of granulocytic ehrlichiosis to dogs, horses, and humans...
Serologic and molecular evidence of Ehrlichia spp. in coyotes in CaliforniaN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
J Wildl Dis 36:494-9. 2000..equi from California. Thus, coyotes are exposed to granulocytic ehrlichiae and E. risticii and may play a role in the epidemiology of these ehrlichial agents in California...
Infection rate of Ehrlichia risticii, the agent of Potomac horse fever, in freshwater stream snails (Juga yrekaensis) from northern CaliforniaN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Parasitol 92:151-6. 2000..risticii. The number of snails harboring trematode stages and the number of PCR positive snails varied with the size of the snails, the month of collection, and the geographic origin...
Molecular detection of an Ehrlichia-like agent in rainbow trout (Oncorhynchus mykiss) from Northern CaliforniaN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Parasitol 92:199-207. 2000..sennetsu genogroup. Whether the fish agent infects horses, dogs, or human beings, and whether it causes disease, remain to be determined...
Helminthic transmission and isolation of Ehrlichia risticii, the causative agent of Potomac horse fever, by using trematode stages from freshwater stream snailsN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
J Clin Microbiol 38:1293-7. 2000..The ehrlichial agent was isolated from the blood of experimentally infected horses by culture in murine monocytic cells and identified as E. risticii ultrastructurally and by characterization of three different genes...
Quantitative evaluation of ehrlichial burden in horses after experimental transmission of human granulocytic Ehrlichia agent by intravenous inoculation with infected leukocytes and by infected ticksN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
J Clin Microbiol 37:4042-4. 1999..The data obtained indicated differences in the period of incubation, duration of rickettsemia, and initial and maximal ehrlichial loads between the two routes of infection...
Detection and quantitation of Ehrlichia risticii genomic DNA in infected horses and snails by real-time PCRN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
Vet Parasitol 90:129-35. 2000..The same results were obtained in the conventional nested PCR. The Ehrlichia-load was in the range of 10,000-9,000,000 and 35,000-680, 000,000 Ehrlichia equivalents per microg leukocyte DNA and snail DNA, respectively...
Transmission of Anaplasma phagocytophila (human granulocytic ehrlichiosis agent) in horses using experimentally infected ticks (Ixodes scapularis)N Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Med B Infect Dis Vet Public Health 49:484-8. 2002..Therefore, tick transmission is highly reproducible and can be successfully used in the equine animal model in order to study HGE...
Quantitative real-time PCR for detection of members of the Ehrlichia phagocytophila genogroup in host animals and Ixodes ricinus ticksN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, CH 8057 Zurich, Switzerland
J Clin Microbiol 37:1329-31. 1999....
Serological evidence of infection with Ehrlichia spp. in red foxes (Vulpes vulpes) in SwitzerlandN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, CH 8057 Zurich, Switzerland
J Clin Microbiol 37:1168-9. 1999..8%) of the samples were positive for Ehrlichia phagocytophila, which is an antigen marker for granulocytic ehrlichiosis. In contrast, none of the samples had antibodies specific to Ehrlichia canis, the agent of monocytic ehrlichiosis...
Experimental inoculation with human granulocytic Ehrlichia agent derived from high- and low-passage cell culture in horsesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
J Clin Microbiol 38:1276-8. 2000....
Serological, hematologic, and PCR studies of cattle in an area of Switzerland in which tick-borne fever (caused by Ehrlichia phagocytophila) is endemicN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, Switzerland
Clin Diagn Lab Immunol 5:325-7. 1998..phagocytophila in cattle. The incidence of clinical signs of ehrlichiosis was increased in cattle grazing on the pastures of endemicity for the first time...
Diagnostic sensitivity of nasopharyngeal and nasal swabs for the molecular detection of EHV-1N Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA
Vet Rec 162:520-1. 2008
Susceptibility of cattle to infection with Ehrlichia equi and the agent of human granulocytic ehrlichiosisN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
J Am Vet Med Assoc 218:1160-2. 2001..Therefore, E equi and the agent of HGE are likely of negligible importance for cattle in North America...
Detection of Ehrlichia phagocytophila DNA in Ixodes ricinus ticks from areas in Switzerland where tick-borne fever is endemicN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, CH 8057 Zurich, CH 8044 Zurich, Switzerland
J Clin Microbiol 36:2735-6. 1998..Of the ticks from cattle with ehrlichiosis, the ticks from healthy cattle, and the free-living ticks, 26.5% (18 of 68), 4.4% (35 of 802), and 0.8% (5 of 653), respectively, were positive...
Detection of EHV-1 neuropathogenic strains using real-time PCR in the neural tissue of horses with myeloencephalopathyC M Leutenegger
Lucy Whittier Molecular and Diagnostic Care Facility, Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA
Vet Rec 162:688-90. 2008
Granulocytic ehrlichiosis in two dogs in SwitzerlandN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, Switzerland
J Clin Microbiol 35:2307-9. 1997..phagocytophila in three and two positions, respectively. Interestingly, the nucleotide sequence of the 16S rRNA was 100% homologous to that of a human granulocytic ehrlichia...
Laboratory findings in cows after experimental infection with Ehrlichia phagocytophilaN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, Switzerland
Clin Diagn Lab Immunol 4:643-7. 1997..E. phagocytophila DNA was detected in blood samples by nested PCR from 1 to 2 days before to 2 to 12 days after the organisms were identified microscopically. In milk samples, E. phagocytophila DNA was detected for an average of 11 days...
Identification of a granulocytic Ehrlichia strain isolated from a horse in Switzerland and comparison with other rickettsiae of the Ehrlichia phagocytophila genogroupN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, Switzerland
J Clin Microbiol 36:2035-7. 1998..equi at two and three positions, respectively. Interestingly, the nucleotide sequence of the 16S rRNA was 100% identical to that of the agent of human granulocytic ehrlichiosis...
Cytokine gene signatures in neural tissue of horses with equine protozoal myeloencephalitis or equine herpes type 1 myeloencephalopathyN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 159:341-6. 2006..In the horses with ehv-1 the proinflammatory cytokine IL-8 was commonly expressed, but IL-10 and IFN-gamma were not, and TNF-alpha was rare. Tissue from the control horses expressed only the gene GAPDH...
Evaluation of the field efficacy of an avirulent live Lawsonia intracellularis vaccine in foalsN Nógrádi
William R Pritchard Veterinary Medical Teaching Hospital, University of California Davis, CA 95616, USA
Vet J 192:511-3. 2012..This decreased disease prevalence in the study population may be associated with the ongoing vaccine trial on these farms, as disease prevalence in Central Kentucky did not change in 2009 compared to 2008...
Seroprevalence of Ehrlichia canis and of canine granulocytic Ehrlichia infection in dogs in SwitzerlandN Pusterla
Department of Veterinary Internal Medicine, University of Zurich, Zurich, Switzerland
J Clin Microbiol 36:3460-2. 1998..canis is not indigenous to Switzerland...
Lawsonia intracellularis proliferative enteropathy in a foalD J Feary
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA, USA
Schweiz Arch Tierheilkd 149:129-33. 2007..intracellularis, despite being clinically normal, and identified a dog as a potential carrier and source of infection for the foal. The foal was successfully treated with a combination of azithromycin and rifampin...
Nucleic acid extraction methods for detection of EHV-1 from blood and nasopharyngeal secretionsS Mapes
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 162:857-9. 2008
Idiopathic granulomatous pneumonia in seven horsesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 153:653-5. 2003..Idiopathic granulomatous pneumonia was confirmed histologically in each of the horses, either postmortem or by a lung biopsy. The horses responded poorly to medical treatment and only one of three treated horses is still alive...
Diagnostic evaluation of real-time PCR in the detection of Rhodococcus equi in faeces and nasopharyngeal swabs from foals with pneumoniaN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 161:272-5. 2007
Disseminated pulmonary adiaspiromycosis caused by Emmonsia crescens in a horseN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
Equine Vet J 34:749-52. 2002
Purpura haemorrhagica in 53 horsesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 153:118-21. 2003..Two of the four non-survivors had been vaccinated against S. equi with a product containing the M protein, one had a S. equi infection and the other had a respiratory infection of undetermined aetiology...
Investigation of the molecular detection of vaccine-derived equine herpesvirus type 1 in blood and nasal secretions from horses following intramuscular vaccinationNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA
J Vet Diagn Invest 19:290-3. 2007..However, the study results demonstrate that detection of EHV-1 DNA by PCR in vaccinated and unvaccinated healthy horses is not a common event...
Characterization of viral loads, strain and state of equine herpesvirus-1 using real-time PCR in horses following natural exposure at a racetrack in CaliforniaNicola Pusterla
Department of Medicine and Epidemiology, University of California, Davis, CA 95616, USA
Vet J 179:230-9. 2009..The molecular approach used in this study showed promise for assessing the risk of exposing other horses to EHV-1 and for studying viral kinetics in infected horses...
Intestinal neoplasia in horsesS D Taylor
From the Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Intern Med 20:1429-36. 2006..CONCLUSIONS: Arabian horses were 4.5 times more likely to have intestinal neoplasia diagnosed than were other breeds...
Internal abdominal abscesses caused by Streptococcus equi subspecies equi in 10 horses in California between 1989 and 2004N Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA
Vet Rec 160:589-92. 2007
Comparison of five real-time PCR assays for detecting virulence genes in isolates of Escherichia coli from septicaemic neonatal foalsS Mapes
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 1 Shields Avenue, Davis, CA 95616, USA
Vet Rec 161:716-8. 2007..The lowest detection rate and amplification efficiency of the E coli isolates was found for the lutA gene...
Molecular evidence of coinfection of ticks with Borrelia burgdorferi sensu lato and the human granulocytic ehrlichiosis agent in SwitzerlandC M Leutenegger
Clinical Laboratory, Department of Internal Veterinary Medicine, University of Zurich, 8057 Zurich, Switzerland
J Clin Microbiol 37:3390-1. 1999..Of 100 ticks, 49% were positive for B. burgdorferi and 2% were positive for the HGE agent. The two HGE agent-positive ticks were also found to be positive for B. burgdorferi...
Serologic cross-reactivity between Anaplasma marginale and Anaplasma phagocytophilumU M Dreher
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
Clin Diagn Lab Immunol 12:1177-83. 2005..marginale and A. phagocytophilum infection of several animal species. In view of these new findings, tests that have been considered specific for either infection must be interpreted carefully...
Ehrlichial diseasesJ E Madigan
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California, USA
Vet Clin North Am Equine Pract 16:487-99, ix. 2000..Its occurrence is associated with aquatic habitats. The natural route of transmission is oral, through the ingestion of E. risticii infected trematode stages either free in water or in an intermediate host, such as aquatic animals...
Immunoglobulin A monoclonal gammopathy in two horses with multiple myelomaN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 155:19-23. 2004..The other horse was treated for a bacterial pneumonia and was still alive six months after it was first examined...
Idiopathic immune-mediated polysynovitis in three horsesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA
Vet Rec 159:13-5. 2006....
Streptococcus equi meningoencephalomyelitis in a foalCarrie Finno
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, 95616, USA
J Am Vet Med Assoc 229:721-4. 2006..CLINICAL RELEVANCE: Findings suggest that S equi subsp equi meningoencephalomyelitis should be considered in the differential diagnosis for foals with neurologic signs that have a history of strangles or exposure to affected horses...
Experimental infection of horses with Bartonella henselae and Bartonella bovisJ Palmero
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Intern Med 26:377-83. 2012..Experimental infection of horses with Bartonella species is not documented...
Ultrasonographic findings in cattle with pleuropneumoniaU Braun
Clinic of Veterinary Internal Medicine, University of Zurich, Switzerland
Vet Rec 141:12-7. 1997..The diagnosis was confirmed at slaughter in three of them; the fourth animal was treated and was clinically healthy when it was discharged...
Granular cell tumours in the lungs of three horsesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
Vet Rec 153:530-2. 2003
Antemortem diagnosis of equine mesothelioma by pleural biopsyM M Fry
School of Veterinary Medicine, Veterinary Medical Teaching Hospital, The University of California, Davis, California 95616, USA
Equine Vet J 35:723-7. 2003
Prevalence of equine herpesvirus-1 infection among Thoroughbreds residing on a farm on which the virus was endemicJames A Brown
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Am Vet Med Assoc 231:577-80. 2007..To determine the incidence of equine herpesvirus-1 (EHV-1) infection among Thoroughbreds residing on a farm on which the virus was known to be endemic...
Equine herpesvirus-4 kinetics in peripheral blood leukocytes and nasopharyngeal secretions in foals using quantitative real-time TaqMan PCRNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
J Vet Diagn Invest 17:578-81. 2005..Based on these results, it was concluded that lytic infection with EHV-4 can be diagnosed either by high EHV-4 DNA load of glycoprotein B gene or by detection of transcriptional activity of glycoprotein B...
Gastric neoplasia in horsesS D Taylor
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA, USA
J Vet Intern Med 23:1097-102. 2009..Gastric neoplasia of horses is incompletely described...
Metallic foreign bodies in the tongues of 16 horsesN Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Rec 159:485-8. 2006..Feeding hay and the use of cable-framed tractor tyres as feeders were commonly associated with the cases...
Pharmacokinetics of intrarectal omeprazole in alpacasT Marmulak
W R Pritchard Veterinary Medical Teaching Hospital, University of California, Davis, CA 95616, USA
J Vet Pharmacol Ther 33:371-5. 2010..As a result of the low measured omeprazole plasma concentrations, it is assumed that rectal absorption of omeprazole is poor in alpacas and not an effective route of administration...
Idiopathic chronic eosinophilic pneumonia in 7 horsesS A Bell
Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Intern Med 22:648-53. 2008..Idiopathic chronic eosinophilic pneumonia of horses is incompletely described...
Outcome of tactile conditioning of neonates, or "imprint training" on selected handling measures in foalsSharon J Spier
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA, USA
Vet J 168:252-8. 2004..It appeared that neonatal imprint training resulted in a learned behaviour that resulted in decreased self-defence responses towards handling the limbs at three months of age...
Two cases of Neorickettsia (Ehrlichia) risticii infection in horses from Nova ScotiaMeera C Heller
Atlantic Veterinary College, University of Prince Edward Island, 56 University Avenue, Charlottetown, Prince Edward Island C1A 4P3
Can Vet J 45:421-3. 2004..These are the first reported cases of PHF in the Maritime Provinces...
Use of dried blood smears for detection of feline hemoplasmas using real-time polymerase chain reactionJane E Sykes
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Diagn Invest 20:616-20. 2008..The improved sensitivity of real-time PCR on blood smears for M. haemofelis compared with that of the other hemoplasma species may reflect the higher organism burdens associated with infection with this species...
Rattlesnake envenomation in 12 New World camelidsSusanne Dykgraaf
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616, USA
J Vet Intern Med 20:998-1002. 2006..Rattlesnake envenomation of New World camelids is a seasonal problem with often dramatic clinical signs...
Effects of blood contamination of cerebrospinal fluid on results of indirect fluorescent antibody tests for detection of antibodies against Sarcocystis neurona and Neospora hughesiCarrie J Finno
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Diagn Invest 19:286-9. 2007..The IFAT performed on CSF is reliable for testing horses for equine protozoal myeloencephalitis caused by S. neurona or N. hughesi, even when blood contamination causes the RBC concentration in CSF to be up to 10,000 RBCs/microl...
Equine protozoal myeloencephalitis associated with neosporosis in 3 horsesCarrie J Finno
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616 2007, USA
J Vet Intern Med 21:1405-8. 2007
Assessment of vitamin E concentrations in serum and cerebrospinal fluid of horses following oral administration of vitamin EJamie K Higgins
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Am J Vet Res 69:785-90. 2008..To determine concentrations of alpha-tocopherol in serum and CSF of healthy horses following administration of supplemental vitamin E in feed...
Comparative analysis of cytokine gene expression in cerebrospinal fluid of horses without neurologic signs or with selected neurologic disordersNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, 95616, USA
Am J Vet Res 67:1433-7. 2006....
Successful treatment and polymerase chain reaction (PCR) confirmation of Tyzzer's disease in a foal and clinical and pathologic characteristics of 6 additional foals (1986-2005)Angela Borchers
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, USA
J Vet Intern Med 20:1212-8. 2006..CONCLUSIONS AND CLINICAL IMPORTANCE: Although the mortality rate of Tyzzer's disease is high, successful outcome is possible if intensive care is initiated promptly. PCR can be used for early and specific diagnosis...
The immune response of foals to natural infection with equid herpesvirus-2 and its association with febrile illnessStephanie A Brault
Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Immunol Immunopathol 137:136-41. 2010..These results support the conclusion that the cellular immune response to EHV-2 may lead to an immunologically mediated disease of foals that is analogous to infectious mononucleosis caused by EBV infection in humans...
Cutaneous and ocular habronemiasis in horses: 63 cases (1988-2002)Nicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Am Vet Med Assoc 222:978-82. 2003..In general, the prognosis was good, and healing occurred within a few weeks. Fly control and regular deworming with ivermectin are recommended to reduce the incidence of habronemiasis...
What is your diagnosis? Occipitoatlantoaxial malformationStephanie Bell
Departments of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Am Vet Med Assoc 231:1033-4. 2007
Expression of molecular markers in blood of neonatal foals with sepsisNicola Pusterla
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Am J Vet Res 67:1045-9. 2006..CONCLUSIONS AND CLINICAL RELEVANCE: The cytokine profile in foals with sepsis may suggest an immunosuppressive state. Expression of IL-10 may be a marker for identification of foals with a guarded prognosis...
Isolation of a gammaherpesvirus similar to asinine herpesvirus-2 (AHV-2) from a mule and a survey of mules and donkeys for AHV-2 infection by real-time PCRStephanie A Bell
Equine Viral Disease Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Microbiol 130:176-83. 2008..AHV-2 was detected by real-time polymerase chain reaction assay in the NS of approximately 8% of a cohort of 114 healthy mules and 13 donkeys...
Long-term outcome associated with intratumoral chemotherapy with cisplatin for cutaneous tumors in equidae: 573 cases (1995-2004)Alain P Theon
Department of Surgery, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Am Vet Med Assoc 230:1506-13. 2007..To determine outcome associated with cutaneous tumors treated via intratumoral chemotherapy with cisplatin and identify risk factors affecting local tumor control and complications in equidae...
In vitro evaluation of three bacterial culture systems for the recovery of Escherichia coli from equine bloodMireia Lorenzo-Figueras
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Am J Vet Res 67:2025-9. 2006....
Evaluation of the SNAP foal IgG test for the semiquantitative measurement of immunoglobulin G in foalsN Pusterla
Department of Medicine and Epidemiology, Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616-8737, USA
Vet Rec 151:258-60. 2002..The intermediate concentrations were usually lower when measured by the SNAP test than by the SRID test, possibly owing to the variable volume of blood added to the test with the sample loop...
Comparison of Coccidioides immitis serological antibody titres between forms of clinical coccidioidomycosis in horsesJill C Higgins
Loomis Basin Large Animal Services, Loomis, CA 95650, USA
Vet J 173:118-23. 2007..Measurement of serological titre may be a useful diagnostic aid in establishing form and severity of disease and thus inform prognosis...
Ehrlichioses in humans: epidemiology, clinical presentation, diagnosis, and treatmentJ Stephen Dumler
Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Clin Infect Dis 45:S45-51. 2007....
Investigation of Bartonella infection in ixodid ticks from CaliforniaChao-Chin Chang
Department of Public Health, Institute of Environmental Health, China Medical College, Taichung, Taiwan, ROC
Comp Immunol Microbiol Infect Dis 25:229-36. 2002..pacificus nymphs and in Dermacentor sp. ticks. Distribution of Bartonella among ixodid ticks appears widespread in California...
