J Q Purnell

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Effect of excessive weight gain with intensive therapy of type 1 diabetes on lipid levels and blood pressure: results from the DCCT. Diabetes Control and Complications Trial
    J Q Purnell
    Department of Medicine, University of Washington, Seattle 98195, USA
    JAMA 280:140-6. 1998
  2. ncbi request reprint Levels of leptin during hydrocortisone infusions that mimic normal and reversed diurnal cortisol levels in subjects with adrenal insufficiency
    J Q Purnell
    Department of Medicine, University of Washington, Seattle 98195, USA
    J Clin Endocrinol Metab 84:3125-8. 1999
  3. ncbi request reprint Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects
    J Q Purnell
    Department of Medicine, University of Washington, Seattle 98195, USA
    AIDS 14:51-7. 2000
  4. ncbi request reprint Effect of weight loss with reduction of intra-abdominal fat on lipid metabolism in older men
    J Q Purnell
    Department of Medicine, University of Washington, Seattle 98195, USA
    J Clin Endocrinol Metab 85:977-82. 2000
  5. ncbi request reprint A hepatic lipase gene promoter polymorphism attenuates the increase in hepatic lipase activity with increasing intra-abdominal fat in women
    M C Carr
    Department of Medicine, Divisions of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle 98195 6426, USA
    Arterioscler Thromb Vasc Biol 19:2701-7. 1999
  6. pmc Increased small dense LDL and intermediate-density lipoprotein with albuminuria in type 1 diabetes
    S D Sibley
    Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle 98195, USA
    Diabetes Care 22:1165-70. 1999
  7. ncbi request reprint The contribution of intraabdominal fat to gender differences in hepatic lipase activity and low/high density lipoprotein heterogeneity
    M C Carr
    Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, University of Washington, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 86:2831-7. 2001
  8. ncbi request reprint Changes in LDL density across the menopausal transition
    M C Carr
    Department of Medicine, University of Washington, Seattle 98195 6426, USA
    J Investig Med 48:245-50. 2000
  9. ncbi request reprint Relationship of insulin sensitivity and ApoB levels to intra-abdominal fat in subjects with familial combined hyperlipidemia
    J Q Purnell
    Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, WA, USA
    Arterioscler Thromb Vasc Biol 21:567-72. 2001
  10. ncbi request reprint A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    D E Cummings
    University of Washington, VA Puget Sound Health Care System and Harborview Medical Center, Seattle, Washington 98108, USA
    Diabetes 50:1714-9. 2001

Collaborators

Detail Information

Publications13

  1. pmc Effect of excessive weight gain with intensive therapy of type 1 diabetes on lipid levels and blood pressure: results from the DCCT. Diabetes Control and Complications Trial
    J Q Purnell
    Department of Medicine, University of Washington, Seattle 98195, USA
    JAMA 280:140-6. 1998
    ..Intensive treatment of type 1 diabetes results in greater weight gain than conventional treatment...
  2. ncbi request reprint Levels of leptin during hydrocortisone infusions that mimic normal and reversed diurnal cortisol levels in subjects with adrenal insufficiency
    J Q Purnell
    Department of Medicine, University of Washington, Seattle 98195, USA
    J Clin Endocrinol Metab 84:3125-8. 1999
    ..The circadian variation of leptin levels cannot be accounted for by normal activity of the hypothalamic-pituitary-adrenal axis...
  3. ncbi request reprint Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects
    J Q Purnell
    Department of Medicine, University of Washington, Seattle 98195, USA
    AIDS 14:51-7. 2000
    ..Whether the lipid abnormalities result from changes in metabolism after an improvement in HIV status or are partly attributable to the effects of protease inhibitor use is unknown...
  4. ncbi request reprint Effect of weight loss with reduction of intra-abdominal fat on lipid metabolism in older men
    J Q Purnell
    Department of Medicine, University of Washington, Seattle 98195, USA
    J Clin Endocrinol Metab 85:977-82. 2000
    ..In summary, in men undergoing diet-induced weight loss, only loss of IAF was found to be associated with a reduction in HL, which is associated with beneficial effects on lipid levels...
  5. ncbi request reprint A hepatic lipase gene promoter polymorphism attenuates the increase in hepatic lipase activity with increasing intra-abdominal fat in women
    M C Carr
    Department of Medicine, Divisions of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle 98195 6426, USA
    Arterioscler Thromb Vasc Biol 19:2701-7. 1999
    ..003). We conclude that the LIPC promoter A allele attenuates the increase in HL activity due to IAF in premenopausal women...
  6. pmc Increased small dense LDL and intermediate-density lipoprotein with albuminuria in type 1 diabetes
    S D Sibley
    Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle 98195, USA
    Diabetes Care 22:1165-70. 1999
    ..This population study examines the relationship between LDL density and persistent albuminuria in subjects with type 1 diabetes at the end of the Diabetes Control and Complications Trial (DCCT)...
  7. ncbi request reprint The contribution of intraabdominal fat to gender differences in hepatic lipase activity and low/high density lipoprotein heterogeneity
    M C Carr
    Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, University of Washington, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 86:2831-7. 2001
    ..The higher HL activity in men affects both LDL and HDL heterogeneity and may contribute to the gender difference in cardiovascular risk...
  8. ncbi request reprint Changes in LDL density across the menopausal transition
    M C Carr
    Department of Medicine, University of Washington, Seattle 98195 6426, USA
    J Investig Med 48:245-50. 2000
    ..Characterization of lipoprotein levels and LDL buoyancy across the stages of the menopausal transition has yet to be reported...
  9. ncbi request reprint Relationship of insulin sensitivity and ApoB levels to intra-abdominal fat in subjects with familial combined hyperlipidemia
    J Q Purnell
    Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, WA, USA
    Arterioscler Thromb Vasc Biol 21:567-72. 2001
    ....
  10. ncbi request reprint A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    D E Cummings
    University of Washington, VA Puget Sound Health Care System and Harborview Medical Center, Seattle, Washington 98108, USA
    Diabetes 50:1714-9. 2001
    ..Circulating ghrelin also correlated positively with age (r = 0.701). The clear preprandial rise and postprandial fall in plasma ghrelin levels support the hypothesis that ghrelin plays a physiological role in meal initiation in humans...
  11. ncbi request reprint Metabolic abnormalities in HIV type 1-infected children treated and not treated with protease inhibitors
    A J Melvin
    Division of Pediatric Infectious Disease, Department of Pediatrics, University of Washington, Seattle, Washington 98105, USA
    AIDS Res Hum Retroviruses 17:1117-23. 2001
    ....
  12. ncbi request reprint Changes in 24-h area-under-the-curve ghrelin values following diet-induced weight loss are associated with loss of fat-free mass, but not with changes in fat mass, insulin levels or insulin sensitivity
    J Q Purnell
    Department of Medicine, Center for the Study of Weight Regulation and Associated Disorders, Oregon Health and Science University, Portland, OR, USA
    Int J Obes (Lond) 31:385-9. 2007
    ..To determine which parameters of body composition or metabolism best correlate with changes in 24 h ghrelin levels following weight loss...
  13. ncbi request reprint Adipose tissue fatty acid composition in humans with lipoprotein lipase deficiency
    N F Ullrich
    Department of Medicine, University of Washington School of Medicine, Seattle 30086, USA
    J Investig Med 49:273-5. 2001
    ....