Jolanta B Pucilowska
Affiliation: University of North Carolina
- IGF-I and procollagen alpha1(I) are coexpressed in a subset of mesenchymal cells in active Crohn's diseaseJ B Pucilowska
Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7545, USA
Am J Physiol Gastrointest Liver Physiol 279:G1307-22. 2000..We conclude that increased IGF-I expression in multiple mesenchymal cell subtypes and increased numbers of cells with fibroblast/myofibroblast phenotype are involved in fibrosis associated with CD...
- IGF-I and TGF-beta1 have distinct effects on phenotype and proliferation of intestinal fibroblastsJames G Simmons
Department of Cell and Molecular Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7545, USA
Am J Physiol Gastrointest Liver Physiol 283:G809-18. 2002..We propose that during intestinal inflammation, regulation of activated phenotype and proliferation may require sequential actions of TGF-beta1 and IGF-I, but they may act in concert to increase collagen deposition...