Robert T Pu

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. doi Acinic cell carcinoma of the salivary gland: a continuing medical education case
    Diane A Hall
    Department of Pathology, The University of Michigan Medical School, Ann Arbor, Michigan, USA
    Diagn Cytopathol 36:379-85; quiz 386-7. 2008
  2. ncbi Utility of WT-1, p63, MOC31, mesothelin, and cytokeratin (K903 and CK5/6) immunostains in differentiating adenocarcinoma, squamous cell carcinoma, and malignant mesothelioma in effusions
    Robert T Pu
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Diagn Cytopathol 36:20-5. 2008
  3. ncbi Methylation profiling of mesothelioma using real-time methylation-specific PCR: a pilot study
    Robert T Pu
    Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    Diagn Cytopathol 35:498-502. 2007
  4. ncbi Methylation profiling of urothelial carcinoma in bladder biopsy and urine
    Robert T Pu
    Department of Pathology, Division of Cytopathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Acta Cytol 50:499-506. 2006
  5. ncbi Does Hurthle cell lesion/neoplasm predict malignancy more than follicular lesion/neoplasm on thyroid fine-needle aspiration?
    Robert T Pu
    Department of Pathology, Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Diagn Cytopathol 34:330-4. 2006
  6. ncbi Utility of cytology microarray constructed from effusion cell blocks for immunomarker validation
    Robert T Pu
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 0054, USA
    Cancer 114:300-6. 2008
  7. ncbi Pathologic features of breast cancer associated with complete response to neoadjuvant chemotherapy: importance of tumor necrosis
    Robert T Pu
    Department of Pathology, University of Michigan, Ann Arbor, MI, USA
    Am J Surg Pathol 29:354-8. 2005
  8. ncbi Fine-needle aspiration biopsy of metastatic malignant melanoma resembling a malignant peripheral nerve sheath tumor
    Svetoslav Bardarov
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Diagn Cytopathol 36:754-7. 2008
  9. ncbi Methylation profiling of benign and malignant breast lesions and its application to cytopathology
    Robert T Pu
    Department of Pathology, Division of Cytopathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Mod Pathol 16:1095-101. 2003
  10. ncbi Nodule heterogeneity as shown by size differences between the targeted nodule and the tumor in thyroidectomy specimen: a cause for a false-negative diagnosis of papillary thyroid carcinoma on fine-needle aspiration
    Masood A Siddiqui
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 0054, USA
    Cancer 114:27-33. 2008

Detail Information

Publications26

  1. doi Acinic cell carcinoma of the salivary gland: a continuing medical education case
    Diane A Hall
    Department of Pathology, The University of Michigan Medical School, Ann Arbor, Michigan, USA
    Diagn Cytopathol 36:379-85; quiz 386-7. 2008
  2. ncbi Utility of WT-1, p63, MOC31, mesothelin, and cytokeratin (K903 and CK5/6) immunostains in differentiating adenocarcinoma, squamous cell carcinoma, and malignant mesothelioma in effusions
    Robert T Pu
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Diagn Cytopathol 36:20-5. 2008
    ..A negative stain with MOC31 can exclude lung ADC. Mesothelin, on the other hand, is not useful in the differential diagnosis of ADC, SCC, and MM...
  3. ncbi Methylation profiling of mesothelioma using real-time methylation-specific PCR: a pilot study
    Robert T Pu
    Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    Diagn Cytopathol 35:498-502. 2007
    ..Although preliminary, we demonstrate that real-time MSP can be applied to archival specimens and gene methylation profiling may have potential to be a useful ancillary tool to help distinguish MM from RM...
  4. ncbi Methylation profiling of urothelial carcinoma in bladder biopsy and urine
    Robert T Pu
    Department of Pathology, Division of Cytopathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Acta Cytol 50:499-506. 2006
    ..To test DNA methylation profiling in detection of urothelial carcinoma in urine...
  5. ncbi Does Hurthle cell lesion/neoplasm predict malignancy more than follicular lesion/neoplasm on thyroid fine-needle aspiration?
    Robert T Pu
    Department of Pathology, Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Diagn Cytopathol 34:330-4. 2006
    ..0077). Our results suggest that an FNA diagnosis of HLN does not predict more malignancy than FLN. Males and older patients with a HLN FNA diagnosis carry a higher risk of Hurthle cell carcinoma upon thyroidectomy...
  6. ncbi Utility of cytology microarray constructed from effusion cell blocks for immunomarker validation
    Robert T Pu
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 0054, USA
    Cancer 114:300-6. 2008
    ..To our knowledge, there has been no report of constructing cytology microarray using effusion cell blocks and testing its utility in immunochemical marker validation...
  7. ncbi Pathologic features of breast cancer associated with complete response to neoadjuvant chemotherapy: importance of tumor necrosis
    Robert T Pu
    Department of Pathology, University of Michigan, Ann Arbor, MI, USA
    Am J Surg Pathol 29:354-8. 2005
    ..0062, P = 0.0249, and P = 0.0021, respectively). Although preliminary, our study suggests that the presence of tumor necrosis and ALI in the core biopsy may be important features to be included in the standard report...
  8. ncbi Fine-needle aspiration biopsy of metastatic malignant melanoma resembling a malignant peripheral nerve sheath tumor
    Svetoslav Bardarov
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Diagn Cytopathol 36:754-7. 2008
    ....
  9. ncbi Methylation profiling of benign and malignant breast lesions and its application to cytopathology
    Robert T Pu
    Department of Pathology, Division of Cytopathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Mod Pathol 16:1095-101. 2003
    ..We then analyzed 17 breast FNA biopsy samples with an indeterminate diagnosis. In this setting, MSP had a high specificity (100%) and modest sensitivity (67%) for identifying malignancy...
  10. ncbi Nodule heterogeneity as shown by size differences between the targeted nodule and the tumor in thyroidectomy specimen: a cause for a false-negative diagnosis of papillary thyroid carcinoma on fine-needle aspiration
    Masood A Siddiqui
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 0054, USA
    Cancer 114:27-33. 2008
    ..To the authors' knowledge, the issue of whether the detection of PTC is correlated with nodule heterogeneity has not been studied to date...
  11. doi Comparison of PAX-2, RCC antigen, and antiphosphorylated H2AX antibody (gamma-H2AX) in diagnosing metastatic renal cell carcinoma by fine-needle aspiration
    Matthew J Wasco
    The University of Michigan Medical School, Department of Pathology, Ann Arbor, Michigan 48109 0602, USA
    Diagn Cytopathol 36:568-73. 2008
    ..A combination of all 3 markers identified 87% of cases, and failure to stain for both PAX-2 and gamma-H2AX suggests against, but does not disprove, a diagnosis of RCC...
  12. doi The clinical and diagnostic impact of using standard criteria of adequacy assessment and diagnostic terminology on thyroid nodule fine needle aspiration
    Xin Jing
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 0054, USA
    Diagn Cytopathol 36:161-6. 2008
    ..Furthermore, the cytohistological concordance was slightly better after CAST implementation, indicating that the improvement of diagnostic consistency among pathologists did not sacrifice the diagnostic accuracy...
  13. ncbi Cellular adequacy for thyroid aspirates prepared by ThinPrep: how many cells are needed?
    Claire W Michael
    Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
    Diagn Cytopathol 35:792-7. 2007
    ..A 25-cell increase in average cells per cluster increases the odds of agreement between diagnoses by 65%...
  14. ncbi Diagnosis of foregut and tailgut cysts by endosonographically guided fine-needle aspiration
    Diane A Hall
    Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
    Diagn Cytopathol 35:43-6. 2007
    ..The identification of ciliated columnar cells is the key finding. Cytologic diagnosis via endosonographically guided fine-needle aspiration of foregut/hindgut cyst is accurate and less traumatic than surgical biopsies...
  15. ncbi Restoring satisfactory status in ThinPrep Pap test specimens with too few squamous cells and containing microscopic red blood cells
    Yijun Pang
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Diagn Cytopathol 36:696-700. 2008
    ..Adjustment of the pore size on the ThinPrep filter device may reduce the interference of red blood cells...
  16. doi Expression of gamma-H2AX in melanocytic lesions
    Matthew J Wasco
    Department of Pathology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
    Hum Pathol 39:1614-20. 2008
    ..Based on the overlap in subsets of nevi and melanomas, the potential clinical utility of this antibody remains uncertain until further studies have been carried out in a larger cohort of melanocytic lesions, including borderline cases...
  17. doi Computer-assisted image analysis of amyloid deposits in abdominal fat pad aspiration biopsies
    Svetoslav Bardarov
    Department of Cytopathology, University of Michigan, Ann Arbor, Michigan, USA
    Diagn Cytopathol 37:30-5. 2009
    ..These results are in agreement with the published papers (references here); however, caution should be exercised before drawing firm conclusions because of the small sample size presented here...
  18. ncbi Detection of DNA methylation. Potential applications to diagnostic cytopathology
    Robert T Pu
    Division of Cytopathology, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Acta Cytol 47:247-52. 2003
    ..Also, the introduction of novel chemotherapeutic drugs that target DNA methylation may utilize gene methylation assays on fine needle aspiration biopsies of tumors...
  19. ncbi Fine-needle aspiration of spinal osteoblastoma in a patient with lymphangiomatosis
    Michael G Rhode
    Department of Pathology, University of Michigan Medical School, Ann Arbor, USA
    Diagn Cytopathol 34:295-7. 2006
    ..We believe that this is the first case reporting an osteoblastoma diagnosed by FNA in a lymphangiomatosis patient. We describe the clinical and cytological findings of osteoblastoma and its differential diagnosis...
  20. doi Combining fine needle aspiration with brushing cytology has improved yields in diagnosing pancreatic ductal adenocarcinoma
    Xin Jing
    Department of Pathology, University of Michigan Health System, Ann Arbor, Michigan 48108, USA
    Diagn Cytopathol 37:574-8. 2009
    ..When used in combination, the two modalities complement each other and achieve better diagnostic yield in pancreatic ductal adenocarcinoma than either FNA or BC alone...
  21. ncbi Fine-needle aspiration cytology of Rosai-Dorfman disease of bone
    Xin Jing
    Department of Pathology, University of Michigan Health System, Ann Arbor, Michigan 48109, USA
    Diagn Cytopathol 36:516-8. 2008
    ..The diagnosis was confirmed by concurrent biopsy with immunhistochemical study. Our case highlighted the role of fine-needle aspiration with ThinPrep technique in the diagnosis of Rosai-Dorfman disease...
  22. doi Fine-needle aspiration cytological features of Cherubism
    Xin Jing
    Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Diagn Cytopathol 36:188-9. 2008
    ..These cytologic features were considered consistent with but not diagnostic of Cherubism. Clinical correlations are needed in distinguishing Cherubism from other lesions containing giant cells...
  23. doi Utility of antiphosphorylated H2AX antibody (gamma-H2AX) in diagnosing metastatic renal cell carcinoma
    Matthew J Wasco
    Department of Pathology, The University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Appl Immunohistochem Mol Morphol 16:349-56. 2008
    ..RCC-Ma is 100% specific for RCC, but only when a membranous pattern of staining is interpreted as positive...
  24. ncbi Incidental giardiasis diagnosed by fine-needle aspiration of a phantom cecal "mass"
    Robert T Pu
    Diagn Cytopathol 33:287-8. 2005
  25. doi Flower-like colloid on thyroid fine needle aspiration
    Robert T Pu
    Diagn Cytopathol 36:607-8. 2008
  26. ncbi Synchronous ordinary lipoma and spindle-cell lipoma diagnosed by fine needle aspiration
    Masood A Siddiqui
    Diagn Cytopathol 34:455-6. 2006