P M Pryciak

Summary

Affiliation: University of Massachusetts Medical Center
Country: USA

Publications

  1. pmc Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway
    P M Pryciak
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical Center, Worcester Foundation Campus, Shrewsbury, Massachusetts 01545, USA
    Genes Dev 12:2684-97. 1998
  2. ncbi request reprint MAP kinases bite back
    P M Pryciak
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01605, USA
    Dev Cell 1:449-51. 2001
  3. ncbi request reprint Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins
    K Harris
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, 377 Plantation Street, Worcester, MA 01605, USA
    Curr Biol 11:1815-24. 2001
  4. pmc AKR1 encodes a candidate effector of the G beta gamma complex in the Saccharomyces cerevisiae pheromone response pathway and contributes to control of both cell shape and signal transduction
    P M Pryciak
    Department of Genetics, University of Washington, Seattle 98195 7360, USA
    Mol Cell Biol 16:2614-26. 1996
  5. ncbi request reprint The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating
    A C Butty
    Swiss Institute for Experimental Cancer Research ISREC, Chemin des Boveresses 155, 1066 Epalinges VD, Switzerland
    Science 282:1511-6. 1998
  6. pmc Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae
    J J Moskow
    Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Mol Cell Biol 20:7559-71. 2000

Collaborators

  • T R Hughes
  • Daniel J Lew
  • K Harris
  • R E Lamson
  • J J Moskow
  • A C Butty
  • B Nelson
  • C J Roberts
  • M J Marton
  • C Boone
  • A S Gladfelter
  • M Peter
  • I Herskowitz
  • L S Huang

Detail Information

Publications6

  1. pmc Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway
    P M Pryciak
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical Center, Worcester Foundation Campus, Shrewsbury, Massachusetts 01545, USA
    Genes Dev 12:2684-97. 1998
    ..Moreover, our results suggest that this event promotes kinase cascade activation by delivering the Ste5-associated kinases to the cell surface kinase Ste20, whose function may depend on Cdc42 and Cdc24...
  2. ncbi request reprint MAP kinases bite back
    P M Pryciak
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01605, USA
    Dev Cell 1:449-51. 2001
    ..Recent studies in a model system challenge our understanding of how signal transmission through a MAP kinase cascade proceeds and how signaling specificity may be achieved...
  3. ncbi request reprint Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins
    K Harris
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, 377 Plantation Street, Worcester, MA 01605, USA
    Curr Biol 11:1815-24. 2001
    ..Our results give insight into the mechanisms and physiological importance of pathway insulation and provide a foundation for the design of customized signaling proteins...
  4. pmc AKR1 encodes a candidate effector of the G beta gamma complex in the Saccharomyces cerevisiae pheromone response pathway and contributes to control of both cell shape and signal transduction
    P M Pryciak
    Department of Genetics, University of Washington, Seattle 98195 7360, USA
    Mol Cell Biol 16:2614-26. 1996
    ....
  5. ncbi request reprint The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating
    A C Butty
    Swiss Institute for Experimental Cancer Research ISREC, Chemin des Boveresses 155, 1066 Epalinges VD, Switzerland
    Science 282:1511-6. 1998
    ..Thus, Far1p functions as an adaptor that recruits polarity establishment proteins to the site of extracellular signaling marked by Gbetagamma to polarize assembly of the cytoskeleton in a morphogenetic gradient...
  6. pmc Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae
    J J Moskow
    Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Mol Cell Biol 20:7559-71. 2000
    ....