Research Topics
Species | REBECCA A contact PROSSERSummaryAffiliation: University of Tennessee Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Neuropeptide Y blocks serotonergic phase shifts of the suprachiasmatic circadian clock in vitroR A Prosser
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, M407 Walter s Life Science Building, Knoxville, TN 37996, USA
Brain Res 808:31-41. 1998..These data are the first to demonstrate in vitro interactions between daytime resetting stimuli in the rat, and provide critical insights into mechanisms controlling circadian clock phase...
The mammalian circadian clock exhibits acute tolerance to ethanolRebecca A Prosser
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA
Alcohol Clin Exp Res 33:2088-93. 2009..Here we investigated whether acute tolerance the ethanol occurs with respect to in vitro phase modulation of the SCN clock...
Acute ethanol modulates glutamatergic and serotonergic phase shifts of the mouse circadian clock in vitroR A Prosser
Department of Biochemistry and Cellular and Molecular Biology, Walters Life Sci Building M407, University of Tennessee, Knoxville, TN 37996, USA
Neuroscience 152:837-48. 2008..Thus, acute ethanol disrupts normal circadian clock phase regulation, which could contribute to the physiological and psychological problems associated with alcohol abuse...
Serotonergic pre-treatments block in vitro serotonergic phase shifts of the mouse suprachiasmatic nucleus circadian clockR A Prosser
Department of Biochemistry and Cellular and Molecular Biology, Walters Life Sci Building M407, University of Tennessee, Knoxville, TN 37996, USA
Neuroscience 142:547-55. 2006....
Serotonin phase-shifts the mouse suprachiasmatic circadian clock in vitroRebecca A Prosser
University of Tennessee, Department of Biochemistry and Cellular and Molecular Biology, M407 Walter s Life Sciences Building, Knoxville, TN 37996, USA
Brain Res 966:110-5. 2003..Together, these results demonstrate that the mouse SCN, like that of the rat, is directly sensitive to in vitro phase-resetting by 5-HT...
Intrinsic role of polysialylated neural cell adhesion molecule in photic phase resetting of the Mammalian circadian clockRebecca A Prosser
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996, USA
J Neurosci 23:652-8. 2003..Together, these results establish that such actions of PSA are manifested downstream from presynaptic retinohypothalamic terminals and therefore are intrinsic to the SCN itself...
Leptin phase-advances the rat suprachiasmatic circadian clock in vitroRebecca A Prosser
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, M407 Walter s Life Sciences Building, Knoxville TN 37996, USA
Neurosci Lett 336:139-42. 2003..Phase advances are induced at all circadian times except late subjective night. These data suggest that peripheral signals of energy and metabolism directly modulate the circadian pacemaker in mammals...
Glutamate blocks serotonergic phase advances of the mammalian circadian pacemaker through AMPA and NMDA receptorsR A Prosser
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996, USA
J Neurosci 21:7815-22. 2001..This inhibition by glutamate may be indirect, because it is blocked by both tetrodotoxin and the GABA(A) antagonist, bicuculline...
Melatonin inhibits in vitro serotonergic phase shifts of the suprachiasmatic circadian clockR A Prosser
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA
Brain Res 818:408-13. 1999..These results demonstrate a clear interaction between melatonin and 5-HT in the SCN, and suggest that melatonin and NPY may play similar roles with respect to modulating the phase of the SCN circadian pacemaker in rats...
Translational and transcriptional inhibitors block serotonergic phase advances of the suprachiasmatic nucleus circadian pacemaker in vitroAneta Jovanovska
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville 37996, USA
J Biol Rhythms 17:137-46. 2002....
Tissue-type plasminogen activator-plasmin-BDNF modulate glutamate-induced phase-shifts of the mouse suprachiasmatic circadian clock in vitroXIANG MOU
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee at Knoxville, Knoxville, TN 37996, USA
Eur J Neurosci 30:1451-60. 2009..Given the usual association of these proteins with the extracellular matrix, these data suggest new lines of investigation into the locations and processes modulating mammalian circadian clock phase-resetting...
Research Grants
- Ethanol Effects in the Mammalian Circadian ClockRebecca Prosser; Fiscal Year: 2007..Future Directions: The results of these studies will provide the basis of a more extensive investigation into the effects of acute and chronic ethanol, and ethanol withdrawal, on the mammalian circadian clock. ..
- Ethanol Effects on the Mammalian Circadian ClockREBECCA A contact PROSSER; Fiscal Year: 2010....
