V Prima

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi Cooperative transformation by MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins generated by the variant t(1;19) in acute lymphoblastic leukemia
    V Prima
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610 3633, USA
    Leukemia 21:2470-5. 2007
  2. ncbi Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemia
    V Prima
    Department of Pediatrics, University of Florida College of Medicine and the University of Florida Shands Cancer Center, Gainesville, FL 32610, USA
    Leukemia 19:806-13. 2005
  3. ncbi E2A-ZNF384 and NOL1-E2A fusion created by a cryptic t(12;19)(p13.3; p13.3) in acute leukemia
    C H Zhong
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Leukemia 22:723-9. 2008
  4. ncbi Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study
    H Dhillon
    Department of Physiology, College of Medicine, Box 100274, University of Florida, Gainesville, FL 32610-0274, USA
    Regul Pept 99:69-77. 2001
  5. ncbi Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats
    P J Scarpace
    Geriatric Research, Education and Clinical Center, Department of Veterans Affairs Medical Center, Gainesville, Florida 32608 1197, USA
    Neuropharmacology 42:548-61. 2002
  6. ncbi Hypothalamic delivery of doxycycline-inducible leptin gene allows for reversible transgene expression and physiological responses
    J Wilsey
    Geriatric Research, Education and Clinical Center, Department of Veterans Affairs Medical Center, Gainesville, FL 32608, USA
    Gene Ther 9:1492-9. 2002
  7. ncbi Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: microarray deoxyribonucleic acid-chip analysis of gene expression
    V Prima
    Department of Molecular Genetics and Microbiology, Powell Gene Therapy Center, University of Florida, Gainesville, Florida 32610 0266, USA
    Endocrinology 145:2035-45. 2004

Collaborators

Detail Information

Publications7

  1. ncbi Cooperative transformation by MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins generated by the variant t(1;19) in acute lymphoblastic leukemia
    V Prima
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610 3633, USA
    Leukemia 21:2470-5. 2007
    ..Both MEF2D/DAZAP1 and DAZAP1/MEF2D have oncogenic properties, and co-expression of both fusion proteins is synergistic...
  2. ncbi Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemia
    V Prima
    Department of Pediatrics, University of Florida College of Medicine and the University of Florida Shands Cancer Center, Gainesville, FL 32610, USA
    Leukemia 19:806-13. 2005
    ..Our data implicate MEF2D in human cancer and suggest that MEF2D/DAZAP1 and/or DAZAP1/MEF2D contribute to leukemogenesis by altering signaling pathways normally regulated by wild-type MEF2D and DAZAP1...
  3. ncbi E2A-ZNF384 and NOL1-E2A fusion created by a cryptic t(12;19)(p13.3; p13.3) in acute leukemia
    C H Zhong
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Leukemia 22:723-9. 2008
    ..This is the first report of expression of E2A fusion protein that includes the DNA binding and protein dimerization domains due to a more proximal break in E2A compared to those described previously...
  4. ncbi Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study
    H Dhillon
    Department of Physiology, College of Medicine, Box 100274, University of Florida, Gainesville, FL 32610-0274, USA
    Regul Pept 99:69-77. 2001
    ....
  5. ncbi Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats
    P J Scarpace
    Geriatric Research, Education and Clinical Center, Department of Veterans Affairs Medical Center, Gainesville, Florida 32608 1197, USA
    Neuropharmacology 42:548-61. 2002
    ....
  6. ncbi Hypothalamic delivery of doxycycline-inducible leptin gene allows for reversible transgene expression and physiological responses
    J Wilsey
    Geriatric Research, Education and Clinical Center, Department of Veterans Affairs Medical Center, Gainesville, FL 32608, USA
    Gene Ther 9:1492-9. 2002
    ..A reversible increase in both leptin signal transduction in the hypothalamus and uncoupling protein expression in brown adipose was recorded. This system allows for more precise regulation of gene therapy-mediated fat loss...
  7. ncbi Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: microarray deoxyribonucleic acid-chip analysis of gene expression
    V Prima
    Department of Molecular Genetics and Microbiology, Powell Gene Therapy Center, University of Florida, Gainesville, Florida 32610 0266, USA
    Endocrinology 145:2035-45. 2004
    ..Our results convey a cautionary note regarding potential use of the tested cytokines in therapeutic applications...