Joseph G Pressey

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. doi request reprint Sirolimus therapy for fibromatosis and multifocal renal cell carcinoma in a child with tuberous sclerosis complex
    Joseph G Pressey
    Division of Hematology Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pediatr Blood Cancer 54:1035-7. 2010
  2. pmc Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: a report from the Children's Oncology Group
    Joseph G Pressey
    Division of Oncology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Blood Cancer 57:930-8. 2011
  3. pmc 2D-difference gel electrophoretic proteomic analysis of a cell culture model of alveolar rhabdomyosarcoma
    Joseph G Pressey
    Department of Pediatrics, Division of Hematology Oncology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Proteome Res 10:624-36. 2011
  4. doi request reprint Embryonal rhabdomyosarcoma with a novel t(2;6)(p23;p21.1)
    Joseph G Pressey
    Department of Pediatrics, Division of Hematology Oncology, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 512, Birmingham, AL 35233, USA
    Cancer Genet Cytogenet 187:39-42. 2008
  5. doi request reprint Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model
    Samer Z Kaylani
    Division of Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 414, Birmingham, AL 35233, USA
    Biochem Biophys Res Commun 435:557-61. 2013
  6. pmc CD133 marks a myogenically primitive subpopulation in rhabdomyosarcoma cell lines that are relatively chemoresistant but sensitive to mutant HSV
    Joseph G Pressey
    Division of Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Pediatr Blood Cancer 60:45-52. 2013
  7. doi request reprint Current concepts on the surgical and medical management of osteosarcoma
    Herrick J Siegel
    University of Alabama at Birmingham, Orthopedic Specialties Building, 1313 13th St South, Suite 211, Birmingham, AL 35205, USA
    Expert Rev Anticancer Ther 8:1257-69. 2008
  8. pmc Herpes simplex virus oncolytic therapy for pediatric malignancies
    Gregory K Friedman
    Department of Pediatrics, Children s Hospital of Alabama, University of Alabama at Birmingham, USA
    Mol Ther 17:1125-35. 2009
  9. ncbi request reprint Molecular pathogenesis of rhabdomyosarcoma
    Shujuan J Xia
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, Pennsylvania 19104 6082, USA
    Cancer Biol Ther 1:97-104. 2002
  10. ncbi request reprint Primary Ewing sarcoma of the brain: a case report and literature review
    Syed Ali Jaffar Kazmi
    Division of Neuropathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Diagn Mol Pathol 16:108-11. 2007

Collaborators

Detail Information

Publications12

  1. doi request reprint Sirolimus therapy for fibromatosis and multifocal renal cell carcinoma in a child with tuberous sclerosis complex
    Joseph G Pressey
    Division of Hematology Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pediatr Blood Cancer 54:1035-7. 2010
    ..In an attempt to avoid bilateral nephrectomies, the patient was treated with the mTOR inhibitor sirolimus. Within 6 months of therapy, the fibromatosis and remaining RCC tumors responded substantially with minimal adverse effects...
  2. pmc Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: a report from the Children's Oncology Group
    Joseph G Pressey
    Division of Oncology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Blood Cancer 57:930-8. 2011
    ..A previous report utilizing in situ hybridization has provided initial evidence for the expression of Hh targets GLI1 and PTCH in RMS tumors...
  3. pmc 2D-difference gel electrophoretic proteomic analysis of a cell culture model of alveolar rhabdomyosarcoma
    Joseph G Pressey
    Department of Pediatrics, Division of Hematology Oncology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Proteome Res 10:624-36. 2011
    ..Thus, the 2D-DIGE proteomics methodology described here provided an important discovery approach to the study of RMS biology and complements the findings of previous mRNA expression studies...
  4. doi request reprint Embryonal rhabdomyosarcoma with a novel t(2;6)(p23;p21.1)
    Joseph G Pressey
    Department of Pediatrics, Division of Hematology Oncology, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 512, Birmingham, AL 35233, USA
    Cancer Genet Cytogenet 187:39-42. 2008
    ..Despite the involvement of the 2p23 locus in the translocation, the tumor did not express ALK. The t(2;6)(p23;p21.1) is a novel finding in E-RMS that may provide insight into the pathogenesis of this relatively frequent childhood tumor...
  5. doi request reprint Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model
    Samer Z Kaylani
    Division of Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 414, Birmingham, AL 35233, USA
    Biochem Biophys Res Commun 435:557-61. 2013
    ..Our data provide bases for using rapamycin either alone or in combination with traditional chemotherapeutic drugs to block the pathogenesis of high risk RMS...
  6. pmc CD133 marks a myogenically primitive subpopulation in rhabdomyosarcoma cell lines that are relatively chemoresistant but sensitive to mutant HSV
    Joseph G Pressey
    Division of Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Pediatr Blood Cancer 60:45-52. 2013
    ..Cancer stem cells or cancer-initiating cells (CIC) represent a theorized population of cells that give rise to tumors and are responsible for treatment resistance...
  7. doi request reprint Current concepts on the surgical and medical management of osteosarcoma
    Herrick J Siegel
    University of Alabama at Birmingham, Orthopedic Specialties Building, 1313 13th St South, Suite 211, Birmingham, AL 35205, USA
    Expert Rev Anticancer Ther 8:1257-69. 2008
    ..Biologic targets that will enable new therapies to have maximum effect on tumor cells while minimizing toxicity to the host tissues need to be identified...
  8. pmc Herpes simplex virus oncolytic therapy for pediatric malignancies
    Gregory K Friedman
    Department of Pediatrics, Children s Hospital of Alabama, University of Alabama at Birmingham, USA
    Mol Ther 17:1125-35. 2009
    ....
  9. ncbi request reprint Molecular pathogenesis of rhabdomyosarcoma
    Shujuan J Xia
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, Pennsylvania 19104 6082, USA
    Cancer Biol Ther 1:97-104. 2002
    ..Therefore, despite similarities in the downstream targets of these genetic alterations, the striking cytogenetic and molecular differences between ARMS and ERMS indicate distinct molecular etiologies in these two subtypes...
  10. ncbi request reprint Primary Ewing sarcoma of the brain: a case report and literature review
    Syed Ali Jaffar Kazmi
    Division of Neuropathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Diagn Mol Pathol 16:108-11. 2007
    ..Demonstration of characteristic translocations by molecular studies differentiates CNS-EES from cPNET and help clinicians make informed decisions regarding therapy...
  11. pmc Targeting wild-type and mutant p53 with small molecule CP-31398 blocks the growth of rhabdomyosarcoma by inducing reactive oxygen species-dependent apoptosis
    Jianmin Xu
    Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0019, USA
    Cancer Res 70:6566-76. 2010
    ..Our findings indicate that the ability of CP-31398 to modulate wild-type and mutant p53 results in the inhibition of RMS growth and invasiveness...
  12. doi request reprint Myelofibrosis in a patient with familial hemophagocytic lymphohistiocytosis
    Gregory K Friedman
    Division of Pediatric Hematology Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pediatr Blood Cancer 50:1260-2. 2008
    ..We report a unique case of primary hemophagocytic lymphohistiocytosis (HLH) detected in an infant who had bone marrow biopsies demonstrating myelofibrosis, a finding not previously reported in primary HLH...