Research Topics
Species | Manju L PrasadSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
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Detail Information
Publications
Hierarchical cluster analysis of myoepithelial/basal cell markers in adenoid cystic carcinoma and polymorphous low-grade adenocarcinomaManju L Prasad
Department of Pathology, Ohio State University, Columbus, OH, USA
Mod Pathol 21:105-14. 2008....
Galectin-3, fibronectin-1, CITED-1, HBME1 and cytokeratin-19 immunohistochemistry is useful for the differential diagnosis of thyroid tumorsManju L Prasad
Department of Pathology, The Ohio State University Medical Center, Columbus, OH 43210, USA
Mod Pathol 18:48-57. 2005..An immunohistochemical panel consisting of GAL3, FN1 and HBME1 may be useful in the diagnosis of follicular cell-derived thyroid tumors...
Papillary thyroid carcinomas with and without BRAF V600E mutations are morphologically distinctAlexander Finkelstein
Department of Pathology, Yale School of Medicine, 310 Cedar Street, New Haven, CT06520, USA
Histopathology 60:1052-9. 2012..This study was aimed at identifying distinctive features in tumours with and without the mutation...
Prognostic significance of regulators of cell cycle and apoptosis, p16(INK4a), p53, and bcl-2 in primary mucosal melanomas of the head and neckManju L Prasad
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Head Neck Pathol 6:184-90. 2012..Expression of bcl-2 is associated with better survival in MM. Loss of p16 was seen with tumor progression whereas aberrant p53 expression was frequent in undifferentiated tumor cells...
Thyroid follicular lesion of undetermined significance: Evaluation of the risk of malignancy using the two-tier sub-classificationMatthew J Horne
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
Diagn Cytopathol 40:410-5. 2012..Despite the vague morphologic criteria for this diagnostic category, the indeterminate rate remains relatively low and falls within the NCI recommendation (<7%)...
Expression and significance of cancer testis antigens in primary mucosal melanoma of the head and neckManju L Prasad
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Head Neck 26:1053-7. 2004..Primary mucosal melanomas of the head and neck (HNMM) are rare aggressive malignant tumors that are usually difficult to treat. CTAs may provide useful targets for therapy; however, their expression in HNMM is not known...
Vanishing thyroid tumors: a diagnostic dilemma after ultrasonography-guided fine-needle aspirationOgechukwu P Eze
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
Thyroid 23:194-200. 2013..In this study, we highlight the diagnostic and management issues associated with the unintended consequences of ultrasonography (US)-guided FNA...
MSG-1 expression in benign and malignant melanocytic lesions of cutaneous and mucosal epitheliumParish P Sedghizadeh
Department of Oral and Maxillofacial Pathology, College of Dentistry, The Ohio State University, Columbus, OH, USA
Med Sci Monit 11:BR189-94. 2005..Its infrequent expression in melanocytic lesions limits its diagnostic value as an immunohistochemical marker in routine pathology practice...
BRAFV600E mutation in papillary thyroid microcarcinoma: a genotype-phenotype correlationRenu K Virk
Department of Pathology, Yale School of Medicine, New Haven, CT, USA
Mod Pathol 26:62-70. 2013..BRAF(V600E) mutation is an early event in thyroid carcinogenesis, and is associated with distinctive morphology and aggressive features even in papillary thyroid microcarcinomas...
BRAF Mutation Testing of Thyroid Fine-Needle Aspiration Specimens Enhances the Predictability of Malignancy in Thyroid Follicular Lesions of Undetermined SignificanceAdebowale J Adeniran
Department of Pathology, Yale University School of Medicine, New Haven, Conn, USA
Acta Cytol 55:570-5. 2011..6%, respectively. The limited data supports the use of BRAF mutation analysis to predict the risk of malignancy in patients with indeterminate thyroid FNAs...
Intracellular versican expression in mesenchymal spindle cell tumors contrasts with extracellular expression in epithelial and other tumors--a tissue microarray-based studyAtul Bhardwaj
Department of Pathology, The Ohio State University Medical Center, Columbus, OH, USA
Appl Immunohistochem Mol Morphol 16:263-6. 2008....
Reflex BRAF testing in thyroid fine-needle aspiration biopsy with equivocal and positive interpretation: a prospective studyAdebowale J Adeniran
Department of Pathology, Yale University, New Haven, Connecticut 06520, USA
Thyroid 21:717-23. 2011..Reflex BRAF testing may improve the diagnostic accuracy of thyroid fine-needle aspiration (FNA) tests having equivocal cytologic interpretations and provide prognostic information that helps guide management in patients with PTC...
Comparative evaluation of high-throughput small-core (0.6-mm) and large-core (2-mm) thyroid tissue microarray: is larger better?Susie Jones
Department of Pathology, Ohio State University Medical Center, Columbus, USA
Arch Pathol Lab Med 136:199-203. 2012..6-mm core of a large tumor would give results similar to results of the whole section. However, cores from colloid-filled thyroid follicles, for example in breast carcinoma, may contain fewer cells compared to solid tumors...
Pleomorphic adenoma arising in an incidental midline isthmic thyroid nodule: a case report and review of the literatureGillian H Levy
Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA
Hum Pathol 43:134-7. 2012..We propose the possibility of origin in ectopic salivary gland tissue that may have aberrantly migrated with the median anlage from the foramen cecum in the base of the tongue during embryogenesis...
Primary mucosal melanoma of the head and neck: a proposal for microstaging localized, Stage I (lymph node-negative) tumorsManju L Prasad
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Cancer 100:1657-64. 2004..The current study was conducted to identify histologic predictors of survival in patients with localized, lymph node-negative (Stage I, N0M0) primary mucosal melanomas of the head and neck (HNMM)...
Allelic variation in gene expression in thyroid tissueHuiling He
Human Cancer Genetics Program, The Ohio State University, Columbus, Ohio 43210, USA
Thyroid 15:660-7. 2005..DUOX1 variation in expression was seen in 3 of 13 patients with PTC and 6 of 27 patients with benign disease. Further studies are needed to determine the significance of these and other allelic variations...
Lymphadenoma of the salivary gland: clinicopathological and immunohistochemical analysis of 33 tumorsRaja R Seethala
Department of Pathology, Presbyterian University Hospital, Pittsburgh, PA, USA
Mod Pathol 25:26-35. 2012..Altered immune status may have a role in their etiopathogenesis. Multiple synchronous tumors, origin in buccal mucosa, and malignant transformation may rarely occur...
Variable expression of coxsackie-adenovirus receptor in thyroid tumors: implications for adenoviral gene therapyDerek K Marsee
Medical Scientist Program, The Ohio State University, Columbus, Ohio, USA
Thyroid 15:977-87. 2005..Our study warrants a functional method to evaluate adenoviral infectivity should be developed and instituted prior to clinical trials of adenoviral gene therapy in patients with advanced thyroid cancer...
CITED1 protein expression suggests Papillary Thyroid Carcinoma in high throughput tissue microarray-based studyManju L Prasad
Department of Pathology, Ohio State University, Columbus, Ohio 43210, USA
Thyroid 14:169-75. 2004..CITED1 is preferentially expressed in PTC and may be used as a diagnostic marker of it...
Primary mucosal desmoplastic melanoma of the head and neckManju L Prasad
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Head Neck 26:373-7. 2004..Desmoplastic variants of melanoma rarely affect the mucosa...
Synovial sarcoma with rhabdoid featuresPing Wen
Department of Pathology, The Ohio State University Medical Center, Columbus 43210, USA
Arch Pathol Lab Med 127:1391-2. 2003
Laryngeal candidiasis mimicking malignancyFabio P Nunes
Department of Medicine, University of Massachusetts, Worcester, Massachusetts 01655, USA
Laryngoscope 118:1957-9. 2008..Biopsy of the lesion failed to show any signs of malignancy, and patient responded well to oral fluconazole therapy...
Primary mucosal malignant melanoma of the head and neckSnehal G Patel
Head and Neck Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
Head Neck 24:247-57. 2002..This study aims to assess the outcome and identify clinical and histologic prognostic indicators in a recent cohort of patients with MMHN treated at a single institution...
