Sampath Prahalad

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc Negative association between the chemokine receptor CCR5-Delta32 polymorphism and rheumatoid arthritis: a meta-analysis
    S Prahalad
    Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84132 2206, USA
    Genes Immun 7:264-8. 2006
  2. pmc A comprehensive review of the genetics of juvenile idiopathic arthritis
    Sampath Prahalad
    Assistant Professor of Pediatrics, Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, P, O Box 581289 Salt Lake City, UT 84158 1289, USA
    Pediatr Rheumatol Online J 6:11. 2008
  3. pmc Lack of association of functional CTLA4 polymorphisms with juvenile idiopathic arthritis
    Sampath Prahalad
    Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84158 1289, USA
    Arthritis Rheum 58:2147-52. 2008
  4. pmc Elevated serum levels of soluble CD154 in children with juvenile idiopathic arthritis
    Sampath Prahalad
    Department of Pediatrics, University of Utah, Salt Lake City, UT, USA
    Pediatr Rheumatol Online J 6:8. 2008
  5. pmc Association of two functional polymorphisms in the CCR5 gene with juvenile rheumatoid arthritis
    S Prahalad
    Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah, Salt Lake City, UT 84132 2206, USA
    Genes Immun 7:468-75. 2006
  6. pmc Familial autoimmunity: maternal parent-of-origin effect in juvenile idiopathic arthritis
    Andrew Zeft
    Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84158 1289, USA
    Clin Rheumatol 27:241-4. 2008
  7. ncbi request reprint Familial aggregation of juvenile idiopathic arthritis
    Sampath Prahalad
    University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Arthritis Rheum 50:4022-7. 2004
  8. doi request reprint The genetics of juvenile idiopathic arthritis: what is new in 2010?
    Sheila Angeles-Han
    Department of Pediatrics, Emory University School of Medicine, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA
    Curr Rheumatol Rep 12:87-93. 2010
  9. ncbi request reprint Genetic analysis of juvenile rheumatoid arthritis: approaches to complex traits
    Sampath Prahalad
    Department of Pediatrics, Division of Immunology and Rheumatology, University of Utah School of Medicine, 30 North, 1900 East, Salt Lake City, UT 84132 2206, USA
    Curr Probl Pediatr Adolesc Health Care 36:83-90. 2006
  10. ncbi request reprint Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rheumatoid arthritis
    Sampath Prahalad
    Department of Pediatrics, University of Utah School of Medicine, Salt Lake City 84132, USA
    Arthritis Rheum 46:1851-6. 2002

Collaborators

Detail Information

Publications19

  1. pmc Negative association between the chemokine receptor CCR5-Delta32 polymorphism and rheumatoid arthritis: a meta-analysis
    S Prahalad
    Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84132 2206, USA
    Genes Immun 7:264-8. 2006
    ..0001), suggesting that CCR5-Delta32 is protective against the development of RA. CCR5 blockade in animal models of RA results in amelioration of arthritis, suggesting that CCR5 blockade could also modify disease in patients with RA...
  2. pmc A comprehensive review of the genetics of juvenile idiopathic arthritis
    Sampath Prahalad
    Assistant Professor of Pediatrics, Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, P, O Box 581289 Salt Lake City, UT 84158 1289, USA
    Pediatr Rheumatol Online J 6:11. 2008
    ..Finally we discuss several genetic variants underlying multiple clinically distinct autoimmune phenotypes...
  3. pmc Lack of association of functional CTLA4 polymorphisms with juvenile idiopathic arthritis
    Sampath Prahalad
    Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84158 1289, USA
    Arthritis Rheum 58:2147-52. 2008
    ..Single-nucleotide polymorphisms (SNPs) in CTLA4 have been implicated in susceptibility to several autoimmune disorders, including JIA. This study was undertaken to test 3 functional CTLA4 variants for association with JIA...
  4. pmc Elevated serum levels of soluble CD154 in children with juvenile idiopathic arthritis
    Sampath Prahalad
    Department of Pediatrics, University of Utah, Salt Lake City, UT, USA
    Pediatr Rheumatol Online J 6:8. 2008
    ..Our objectives were to determine if sCD154 is elevated in JIA, and to examine correlations between sCD154 and other inflammatory cytokines...
  5. pmc Association of two functional polymorphisms in the CCR5 gene with juvenile rheumatoid arthritis
    S Prahalad
    Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah, Salt Lake City, UT 84132 2206, USA
    Genes Immun 7:468-75. 2006
    ..05). Both variants are in regions under natural selection, and result in functional consequences. Our results suggest these CCR5 variants are protective against early-onset JRA...
  6. pmc Familial autoimmunity: maternal parent-of-origin effect in juvenile idiopathic arthritis
    Andrew Zeft
    Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84158 1289, USA
    Clin Rheumatol 27:241-4. 2008
    ....
  7. ncbi request reprint Familial aggregation of juvenile idiopathic arthritis
    Sampath Prahalad
    University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Arthritis Rheum 50:4022-7. 2004
    ..To estimate the degree of familial aggregation of juvenile idiopathic arthritis (JIA), determine whether the aggregation of JIA and the aggregation of type 1 diabetes mellitus (type 1 DM) overlap, and identify multiplex JIA pedigrees...
  8. doi request reprint The genetics of juvenile idiopathic arthritis: what is new in 2010?
    Sheila Angeles-Han
    Department of Pediatrics, Emory University School of Medicine, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA
    Curr Rheumatol Rep 12:87-93. 2010
    ..This review highlights recent genetic investigations of JIA...
  9. ncbi request reprint Genetic analysis of juvenile rheumatoid arthritis: approaches to complex traits
    Sampath Prahalad
    Department of Pediatrics, Division of Immunology and Rheumatology, University of Utah School of Medicine, 30 North, 1900 East, Salt Lake City, UT 84132 2206, USA
    Curr Probl Pediatr Adolesc Health Care 36:83-90. 2006
  10. ncbi request reprint Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rheumatoid arthritis
    Sampath Prahalad
    Department of Pediatrics, University of Utah School of Medicine, Salt Lake City 84132, USA
    Arthritis Rheum 46:1851-6. 2002
    ..To determine if the prevalence of autoimmunity among relatives of patients with juvenile rheumatoid arthritis (JRA) is greater than that among relatives of healthy volunteer control subjects...
  11. ncbi request reprint Lack of association between birth order and juvenile idiopathic arthritis
    Sampath Prahalad
    University of Utah, Salt Lake City, UT, USA
    Arthritis Rheum 48:2989-90. 2003
  12. ncbi request reprint Genetics of juvenile idiopathic arthritis: an update
    Sampath Prahalad
    Department of Pediatrics, Division of Immunology and Rheumatology, University of Utah School of Medicine, Salt Lake City, Utah 84132 2206, USA
    Curr Opin Rheumatol 16:588-94. 2004
    ..This review outlines the principles behind genetic studies and summarizes recent studies on the genetics of JIA...
  13. ncbi request reprint Fatal acute fibrinous and organizing pneumonia in a child with juvenile dermatomyositis
    Sampath Prahalad
    Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    J Pediatr 146:289-92. 2005
    ..We describe a child with juvenile dermatomyositis who had development of acute fibrinous and organizing pneumonia. There does not appear to be a successful method of treatment, particularly in severe cases with respiratory failure...
  14. ncbi request reprint Musculoskeletal abnormalities of the tibia in juvenile rheumatoid arthritis
    Elena M O Felin
    University of Utah, Salt Lake City, UT 84158, USA
    Arthritis Rheum 56:984-94. 2007
    ....
  15. pmc Lack of association between beta 2-adrenergic receptor polymorphisms and juvenile idiopathic arthritis
    G Pont-Kingdon
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA
    Scand J Rheumatol 38:91-5. 2009
    ..Associations between variants in the gene encoding the beta 2-adrenergic receptor (ADRB2) and autoimmune disorders such as rheumatoid arthritis (RA) have been demonstrated. We aimed to investigate ADRB2 variants for association with JIA...
  16. ncbi request reprint Etanercept in the treatment of macrophage activation syndrome
    S Prahalad
    Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Ohio 45229-3039, USA
    J Rheumatol 28:2120-4. 2001
    ..We describe a patient with MAS and sJRA successfully treated with the anti-TNF agent etanercept. The outcome in this patient suggests etanercept might be an effective therapeutic agent in MAS...
  17. ncbi request reprint Juvenile idiopathic arthritis and exposure to fine particulate air pollution
    A S Zeft
    Department of Pediatrics, University of Utah, Salt Lake City, 84158 1289, USA
    Clin Exp Rheumatol 27:877-84. 2009
    ..This study evaluated potential associations between JIA symptom onset and temporal changes in regional air pollution measured by stagnant air conditions and PM2.5 concentrations...
  18. ncbi request reprint Long-term outcome among patients with juvenile rheumatoid arthritis
    S Prahalad
    Division of Rheumatology, Department of Pediatrics, Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Front Biosci 3:e13-22. 1998
    ..Several of the instruments that are available for assessing outcome among patients are described. The role of laboratory and radiological evaluation in predicting outcome is also addressed...
  19. ncbi request reprint A genome-wide scan for juvenile rheumatoid arthritis in affected sibpair families provides evidence of linkage
    Susan D Thompson
    Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Arthritis Rheum 50:2920-30. 2004
    ..A genome scan was performed to detect linkage to JRA in 121 families containing 247 affected children in North America (the JRA Affected Sibpair [ASP] Registry)...