Amynah Pradhan

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Ligand-directed signalling within the opioid receptor family
    Amynah A Pradhan
    Semel Institute for Neuropsychiatry and Human Behavior, University of California Los Angeles, Los Angeles, CA 90024 1759, USA
    Br J Pharmacol 167:960-9. 2012
  2. pmc Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance
    Amynah A A Pradhan
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Centre National de la Recherche Scientifique Institut National de la Santé et de la Recherche Médicale Université de Strasbourg, 67404 Illkirch, France
    J Neurosci 30:16459-68. 2010
  3. pmc Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2
    Hoa Lam
    Institute of Academic Anaesthesia, Centre for Neuroscience, University of Dundee, Dundee DD19SY, UK
    Mol Pain 7:24. 2011
  4. pmc Chronic inflammatory injury results in increased coupling of delta opioid receptors to voltage-gated Ca2+ channels
    Amynah Pradhan
    Department of Neuropsychiatry and Biobehavioral Sciences, Stefan and Shirley Hatos Center for Neuropharmacology, Semel Institute, University of California, Los Angeles, CA 90095, USA
    Mol Pain 9:8. 2013

Collaborators

  • Hoa Lam
  • Tim G Hales
  • Christopher J Evans
  • Matthew Maga
  • Wendy Walwyn
  • Nigel T Maidment

Detail Information

Publications4

  1. pmc Ligand-directed signalling within the opioid receptor family
    Amynah A Pradhan
    Semel Institute for Neuropsychiatry and Human Behavior, University of California Los Angeles, Los Angeles, CA 90024 1759, USA
    Br J Pharmacol 167:960-9. 2012
    ..This understanding could eventually lead to the development of tailor-made pharmacotherapies where advantageous drug effects can be selectively targeted over adverse effects...
  2. pmc Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance
    Amynah A A Pradhan
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Centre National de la Recherche Scientifique Institut National de la Santé et de la Recherche Médicale Université de Strasbourg, 67404 Illkirch, France
    J Neurosci 30:16459-68. 2010
    ..Hence, ligand-directed receptor trafficking of the δ-opioid receptor engages distinct adaptive responses, and this study reveals a novel aspect of biased agonism in vivo...
  3. pmc Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2
    Hoa Lam
    Institute of Academic Anaesthesia, Centre for Neuroscience, University of Dundee, Dundee DD19SY, UK
    Mol Pain 7:24. 2011
    ..By contrast, the aversive effects of inverse agonists were similar in β-arr2⁻/⁻ and β-arr2+/+ mice, suggesting that hedonic tone was unaffected...
  4. pmc Chronic inflammatory injury results in increased coupling of delta opioid receptors to voltage-gated Ca2+ channels
    Amynah Pradhan
    Department of Neuropsychiatry and Biobehavioral Sciences, Stefan and Shirley Hatos Center for Neuropharmacology, Semel Institute, University of California, Los Angeles, CA 90095, USA
    Mol Pain 9:8. 2013
    ..In addition, as beta-arrestin 2 can regulate delta opioid receptor trafficking and signaling, we have further examined whether deleting this scaffolding and signal transduction molecule alters delta opioid receptor function...