Research Topics
Genomes and Genes
Species | Jenny N PoynterSummaryAffiliation: University of Southern California Country: USA Publications
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Detail Information
Publications
Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family RegistryJenny N Poynter
Department of Preventive Medicine, University of Southern California, 1441 Eastlake Avenue, NOR4411A, Los Angeles, CA 90089 9175, USA
Cancer Res 67:11128-32. 2007..These data suggest that common variants may play important roles in the risk of CRC...
A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer riskA Joan Levine
USC Keck School of Medicine, Department of Preventive Medicine, Genetic Epidemiology, NRT 1450 Biggy Street Room 1509A, Los Angeles, CA 90033, USA
Cancer Epidemiol Biomarkers Prev 19:1812-21. 2010..Folate-associated one-carbon metabolism (FOCM) may play an important role in colorectal carcinogenesis. Variation in FOCM genes may explain some of the underlying risk of colorectal cancer...
Genes involved with folate uptake and distribution and their association with colorectal cancer riskJane C Figueiredo
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1450 Biggy Street Room 1509J, Los Angeles, CA 90033, USA
Cancer Causes Control 21:597-608. 2010..In conclusion, we found no significant evidence that genetic variants in FOLR1, GGH, FPGS and SLC19A1 are associated with the risk of colorectal cancer...
Risk of contralateral breast cancer associated with common variants in BRCA1 and BRCA2: potential modifying effect of BRCA1/BRCA2 mutation carrier statusJane C Figueiredo
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Harlyne J Norris Cancer Research Tower, 1450 Biggy Street Room 1509J, Los Angeles, CA 90033, USA
Breast Cancer Res Treat 127:819-29. 2011..The association between common variants in BRCA1 and BRCA2 and risk of CBC may differ depending on BRCA1 and BRCA2 mutation carrier status...
Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family RegistryJenny N Poynter
Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA
Cancer Epidemiol Biomarkers Prev 19:525-36. 2010..Overall, our results do not provide evidence for a role of common genetic variants in VDR or GC in susceptibility to CRC...
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability statusJenny N Poynter
Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA
Cancer Epidemiol Biomarkers Prev 18:2745-50. 2009..Reports have suggested that these associations may differ by tumor molecular subtype, with stronger associations for microsatellite unstable (MSI-H) tumors...
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screeningJenny N Poynter
Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033 9176, USA
Cancer Epidemiol Biomarkers Prev 17:3208-15. 2008..These results reinforce the importance of distinguishing between the underlying causes of MSI in studies of etiology and prognosis...
Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registryA Joan Levine
USC Keck School of Medicine, Department of Preventive Medicine, Genetic Epidemiology, NRT 1450 Biggy Street, Room 1509A, Los Angeles, CA 90033, USA
Cancer Epidemiol Biomarkers Prev 19:89-100. 2010..The MTHFR C677T TT genotype is associated with a 15% to 18% reduction in colorectal cancer risk, but it is not clear if other variants of the gene are associated with colorectal cancer risk...
Reproductive factors and risk of contralateral breast cancer by BRCA1 and BRCA2 mutation status: results from the WECARE studyJenny N Poynter
Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA
Cancer Causes Control 21:839-46. 2010..In this study, we evaluated the association between these factors and CBC risk among BRCA1 and BRCA2 (BRCA1/2) mutation carriers and non-carriers...
BRAF and NRAS mutations in melanoma and melanocytic neviJenny N Poynter
Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109 2200, USA
Melanoma Res 16:267-73. 2006..We suggest that BRAF mutations contribute to benign melanocytic hyperplasia, but are likely to contribute to invasive melanoma only in conjunction with other mutations...
APC I1307K and the risk of prostate cancerJenny N Poynter
Division of Molecular Medicine and Genetics, University of Michigan, 4301 MSRB III, Ann Arbor, MI 48109 0638, USA
Cancer Epidemiol Biomarkers Prev 15:468-73. 2006..Overall, the evidence for an association between APC I1307K and prostate cancer is not compelling. APC I1307K is unlikely to play a clinically meaningful role in susceptibility to prostate cancer...
Statins and the risk of colorectal cancerJenny N Poynter
Department of Epidemiology, University of Michigan, Ann Arbor 48109-0638, USA
N Engl J Med 352:2184-92. 2005..Because the absolute risk reduction is likely low, further investigation of the overall benefits of statins in preventing colorectal cancer is warranted...
