Research Topics
| Jean PouliotSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Dose calculation using megavoltage cone-beam CTOlivier Morin
Comprehensive Cancer Center, Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA 94143, USA
Int J Radiat Oncol Biol Phys 67:1201-10. 2007..To demonstrate the feasibility of performing dose calculation on megavoltage cone-beam CT (MVCBCT) of head-and-neck patients in order to track the dosimetric errors produced by anatomic changes...- [Megavoltage cone-beam CT: Recent developments and clinical applications]J Pouliot
Department of Radiation Oncology, University of California San Francisco, Comprehensive Cancer Center, 1600 Divisadero Street, Suite H1031, San Francisco, CA 94143, USA
Cancer Radiother 10:258-68. 2006..Examples of the image-guided treatment process from the acquisition of the MV CBCT scan to the correction of the couch position and dose delivery will be presented for spinal and lung lesions and for head and neck, and prostate cancers... - Kilovoltage volumetric imaging in the treatment roomD A Jaffray
Radiation Medicine Program, Princess Margaret Hospital Ontario Cancer Institute Department of Radiation Oncology and Medical Biophysics, University of Toronto, Toronto, Canada
Front Radiat Ther Oncol 40:116-31. 2007..These imaging technologies will lead to a better understanding of the weaknesses, and provide opportunity to reduce errors and improve technical execution of radiotherapy delivery... - (Non)-migration of radiopaque markers used for on-line localization of the prostate with an electronic portal imaging deviceJean Pouliot
Department of Radiation Oncology, University of California San Francisco, Comprehensive Cancer Center, San Francisco, CA, USA
Int J Radiat Oncol Biol Phys 56:862-6. 2003..Radiopaque gold markers can be implanted in the prostate to visualize its position on portal images during radiation therapy. This procedure assumes that the markers do not move within the prostate. In this work we test this assumptiom... - Megavoltage imaging, megavoltage cone beam CT and dose-guided radiation therapyJean Pouliot
University of California at San Francisco Comprehensive Cancer Center, San Francisco, CA 94143 1708, USA
Front Radiat Ther Oncol 40:132-42. 2007..By combining exit dosimetry with the EPID and MV CBCT, this technology may play a key role in tracking the dose delivered to the patient, taking us into an era of dose-guided radiation therapy ... - Inverse planning for HDR prostate brachytherapy used to boost dominant intraprostatic lesions defined by magnetic resonance spectroscopy imagingJean Pouliot
Department of Radiation Oncology, University of California San Francisco, 1600 Divisadero Street, Suite H1031, San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 59:1196-207. 2004..To dose escalate selected regions inside the prostate without compromising the dose coverage of the prostate and the protection to the urethra, rectum, and bladder for prostate cancer patients treated with high-dose-rate brachytherapy... - Low-dose megavoltage cone-beam CT for radiation therapyJean Pouliot
Department of Radiation Oncology, University of California San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 61:552-60. 2005.... - Daily electronic portal imaging of implanted gold seed fiducials in patients undergoing radiotherapy after radical prostatectomyDaniel C Schiffner
Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 67:610-9. 2007..The aim of this study was to measure interfraction prostate bed motion, setup error, and total positioning error in 10 consecutive patients undergoing postprostatectomy radiotherapy... - Patient dose considerations for routine megavoltage cone-beam CT imagingOlivier Morin
Comprehensive Cancer Center Department of Radiation Oncology, University of California San Francisco, San Francisco, California 94143, USA
Med Phys 34:1819-27. 2007..Reducing the imaging volume in the cranio-caudal direction can further reduce the dose delivered for MVCBCT. This is a useful feature to eliminate the imaging dose to the eyes or to focus on a specific region of interest for alignment... - Physical performance and image optimization of megavoltage cone-beam CTOlivier Morin
Department of Radiation Oncology, Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, California 94143, USA
Med Phys 36:1421-32. 2009..Further improvement is expected from the next generation MVCBCT system with an optimized megavoltage imaging beamline... - Dose uncertainty due to computed tomography (CT) slice thickness in CT-based high dose rate brachytherapy of the prostate cancerYongbok Kim
Department of Radiation Oncology, University of California, San Francisco, Mount Zion Comprehensive Cancer Center, 1600 Divisadero Street, San Francisco, California 94143 1708, USA
Med Phys 31:2543-8. 2004..A CT slice thickness of 3 mm appears to be a good compromise showing an acceptable average dose uncertainty of 1%, without unduly increasing the number of slices... 
Comparison of dosimetric and biologic effective dose parameters for prostate and urethra using 131 Cs and 125 I for prostate permanent implant brachytherapyArjun Sahgal
Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA94143, USA
Int J Radiat Oncol Biol Phys 72:247-54. 2008..To compare the urethral and prostate absolute and biologic effective doses (BEDs) for 131 Cs and 125 I prostate permanent implant brachytherapy (PPI)...- Dosimetric impact of interfraction catheter movement in high-dose rate prostate brachytherapyWilliam Foster
Department of Radiation Oncology, University of California San Francisco, San Francisco, California, USA
Int J Radiat Oncol Biol Phys 80:85-90. 2011..To evaluate the impact of interfraction catheter movement on dosimetry in prostate high-dose-rate (HDR) brachytherapy... - Positional stability of electromagnetic transponders used for prostate localization and continuous, real-time trackingDale W Litzenberg
Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 68:1199-206. 2007..Ideally, the distances between transponders remains constant over the course of treatment. In this work, we evaluate the accuracy of these conditions... - Dose recalculation and the Dose-Guided Radiation Therapy (DGRT) process using megavoltage cone-beam CTJoey Cheung
Department of Radiation Oncology, University of California San Francisco, Comprehensive Cancer Center, 94115, USA
Int J Radiat Oncol Biol Phys 74:583-92. 2009..In this article, we present the process of performing dose recalculation on megavoltage cone-beam computed tomography images and discuss possible strategies for dose-guided radiation therapy (DGRT)... - High-dose rate brachytherapy using inverse planning simulated annealing for locoregionally advanced cervical cancer: a clinical report with 2-year follow-upDaniel H Kim
Department of Radiation Oncology, University of California, San Francisco, CA, USA
Int J Radiat Oncol Biol Phys 75:1329-34. 2009..We present clinical outcomes of image-guided brachytherapy using inverse planning simulated annealing (IPSA) planned high-dose rate (HDR) brachytherapy boost for locoregionally advanced cervical cancer... - Measurement of craniocaudal catheter displacement between fractions in computed tomography-based high dose rate brachytherapy of prostate cancerYongbok Kim
Department of Radiation Oncology, University of California San Francisco, Comprehensive Cancer Center, 1600 Divisadero Street, Suite H1031, San Francisco, CA 94143 1708, USA
J Appl Clin Med Phys 8:2415. 2007..We found a pattern of catheter displacement using our technique. Based on our finding further improvement of our results may be possible by modification of our current technique... 
Phase II trial of combined high-dose-rate brachytherapy and external beam radiotherapy for adenocarcinoma of the prostate: preliminary results of RTOG 0321I Chow Hsu
University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 78:751-8. 2010..To estimate the rate of late Grade 3 or greater genitourinary (GU) and gastrointestinal (GI) adverse events (AEs) after treatment with external beam radiotherapy and prostate high-dose-rate (HDR) brachytherapy...- Prostate movement during simulation resulting from retrograde urethrogram compared with "natural" prostate movementYu-Ming Liu
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA
Int J Radiat Oncol Biol Phys 60:470-5. 2004..64 mm, p = 0.004; anteroposterior = 2.24, p = 0.035). CONCLUSIONS: Use of the UG induces a small but clinically insignificant displacement of the prostate when "natural" movement is taken into account... - Three-dimensional conformal external beam radiotherapy compared with permanent prostate implantation in low-risk prostate cancer based on endorectal magnetic resonance spectroscopy imaging and prostate-specific antigen levelBarby Pickett
Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA 94143, USA
Int J Radiat Oncol Biol Phys 65:65-72. 2006..Recent studies have suggested that the treatment of low-risk prostate cancer yields similar results for patients treated with 3D-CRT or PPI... - Comparison of high-dose rate prostate brachytherapy dose distributions with iridium-192, ytterbium-169, and thulium-170 sourcesDevan Krishnamurthy
Department of Radiation Oncology, University of California San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1708, USA
Brachytherapy 10:461-5. 2011..V., Veenendaal, The Netherlands)... - Dosimetric impact of prostate volume change between CT-based HDR brachytherapy fractionsYongbok Kim
Department of Radiation Oncology, Comprehensive Cancer Center, University of California San Francisco, 1600 Divisadero Street, Suite H 1031, San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 59:1208-16. 2004..The objective is to evaluate the prostate volume change and its dosimetric consequences after the insertion of catheters for high-dose-rate brachytherapy... - Surgical resection and permanent iodine-125 brachytherapy for brain metastasesKim Huang
Department of Radiation Oncology, University of California San Francisco, 505 Parnassus Avenue, Room L 08, San Francisco, CA, 94143 0226, USA
J Neurooncol 91:83-93. 2009..To evaluate the efficacy and toxicity of surgical resection and permanent iodine-125 brachytherapy without adjuvant whole brain radiation therapy (WBRT) for brain metastases... - Class solution for inversely planned permanent prostate implants to mimic an experienced dosimetristEtienne Lessard
UCSF Comprehensive Cancer Center, San Francisco, California 94143 1708, USA
Med Phys 33:2773-82. 2006..This technology is not intended to replace the physicist but to accelerate the planning process, making intraoperative treatment planning more effective... - Low dose megavoltage cone beam computed tomography with an unflattened 4 MV beam from a carbon targetBruce A Faddegon
Department of Radiation Oncology, UCSF Comprehesive Cancer Center, San Francisco, California 94143 1708, USA
Med Phys 35:5777-86. 2008.... - Analysis of interaction between number of implant catheters and dose-volume histograms in prostate high- dose-rate brachytherapy using a computer modelClaire Charra-Brunaud
Department of Radiation Oncology, University of California at San Francisco, San Francisco, CA, USA
Int J Radiat Oncol Biol Phys 56:586-91. 2003..In prostate high-dose-rate brachytherapy, to determine before implant, using the standard geometric optimization algorithm, whether there is an optimal number of catheters... - Class solution in inverse planned HDR prostate brachytherapy for dose escalation of DIL defined by combined MRI/MRSIYongbok Kim
Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA 94143 1708, USA
Radiother Oncol 88:148-55. 2008..To establish an inverse planning set of parameters (class solution) to boost dominant intra-prostatic lesion (DIL) defined by MRI/MRSI... - Feasibility of high-dose-rate brachytherapy salvage for local prostate cancer recurrence after radiotherapy: the University of California-San Francisco experienceBrian Lee
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94115, USA
Int J Radiat Oncol Biol Phys 67:1106-12. 2007..The aim of this study was to evaluate the feasibility and safety of salvage high-dose-rate (HDR) brachytherapy for locally recurrent prostate cancer after external beam radiotherapy (EBRT)... - Correction of megavoltage cone-beam CT images of the pelvic region based on phantom measurements for dose calculation purposesJean Francois Aubry
Department of Radiation Oncology, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA
J Appl Clin Med Phys 10:2852. 2009..This correction method enablesMVCBCT images to be used for the verification of the daily dose distribution for patients treated in the pelvis region... - Toward adaptive stereotactic robotic brachytherapy for prostate cancer: demonstration of an adaptive workflow incorporating inverse planning and an MR stealth robotJ Adam Cunha
Department of Radiation Oncology, University of California, San Francisco, CA, USA
Minim Invasive Ther Allied Technol 19:189-202. 2010..Demonstration of this workflow is a key element of a successful translation to the clinic of the MRI stealth robotic delivery system, MRBot... - Comparison of inverse planning simulated annealing and geometrical optimization for prostate high-dose-rate brachytherapyI Chow J Hsu
Department of Radiation Oncology, University of California San Francisco, Comprehensive Cancer Center, 1600 Divisadero Street, Suite H1031, San Francisco, CA 94143 1708, USA
Brachytherapy 3:147-52. 2004..An inverse planning simulated annealing (IPSA) algorithm for optimization of high-dose-rate (HDR) brachytherapy has been previously described. In this study, IPSA is compared with geometrical optimization (GO) for prostate brachytherapy... - Are lateral electronic portal images adequate for accurate on-line daily targeting of the prostate? Results of a prospective studyMichael W Lometti
Department of Radiation Oncology, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA 94143, USA
Med Dosim 33:22-9. 2008..In most circumstances, with exceptions such as morbidly obese patients, acquisition of only a LAT image for daily targeting of the prostate will provide adequate positional precision... - Daily electronic portal imaging for morbidly obese men undergoing radiotherapy for localized prostate cancerLaura Ellen Millender
Department of Radiation Oncology, University of California San Francisco, Comprehensive Cancer Center, San Francisco, CA 94143, USA
Int J Radiat Oncol Biol Phys 59:6-10. 2004..Setup error rather than organ motion appears to be the dominant force in positioning error in obese men... - Comparison of three strategies in management of independent movement of the prostate and pelvic lymph nodesPing Xia
Department of Radiation Oncology, University of California San Francisco, San Francisco, California 94143, USA
Med Phys 37:5006-13. 2010..The purposes of this article are to propose a new management strategy and to compare this strategy to the conventional isocenter shift method and the previously proposed MLC-shifting method... - Physics strategies for sparing neural stem cells during whole-brain radiation treatmentsNeil Kirby
Department of Radiation Oncology, University of California, San Francisco, CA 94143 1708, USA
Med Phys 38:5338-44. 2011..This study investigates the fundamental physics issues associated with the sparing of neural stem cells during photon radiotherapy for brain metastases... - Inverse planning optimization for hybrid prostate permanent-seed implant brachytherapy plans using two source strengthsJ Adam M Cunha
Physics Division, Department of Radiation Oncology, The University of California, San Francisco, CA 94115, USA
J Appl Clin Med Phys 11:3096. 2010.... - Radiation dosimetry of a conformal heat-brachytherapy applicatorRichard Taschereau
Department of Radiation Oncology, University of California, San Francisco, 1600 Divisadero Street, San Franciso, CA 94143-1708, USA
Technol Cancer Res Treat 3:347-58. 2004..Lowering radiation dose by an equivalent factor may produce lower radiation toxicity with similar efficacy, while preserving the option of subsequent retreatment(s) with thermoradiotherapy in order to further extend patient survival... - Investigation of geometric distortions on magnetic resonance and cone beam computed tomography images used for planning and verification of high-dose rate brachytherapy cervical cancer treatmentJean Francois Aubry
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94143, USA
Brachytherapy 9:266-73. 2010.... - Expandable and rigid endorectal coils for prostate MRI: impact on prostate distortion and rigid image registrationYongbok Kim
Department of Radiation Oncology, University of California, San Francisco, Comprehensive Cancer Center 1600 Divisadero Street, Suite H1031, San Francisco, California 94143 1708, USA
Med Phys 32:3569-78. 2005..941 +/- 0.008 vs 0.899 +/- 0.033, for the rigid and expandable coils, respectively). In conclusion, the manual rigid-body alignment of prostate MR images acquired with and without the ERC can be improved through the use of a rigid ERC... - Dosimetric aspects of inverse-planned modulated-arc total-body irradiationMareike Held
Department of Radiation Oncology, University of California San Francisco, California 94143 1708, USA
Med Phys 39:5263-71. 2012..To develop optimal beam parameters and to verify the dosimetric aspects of the recently developed modulated-arc total-body irradiation (MATBI) technique, which delivers an inverse-planned dose to the entire body using gantry rotation... - American Society for Therapeutic Radiology and Oncology (ASTRO) Emerging Technology Committee report on electronic brachytherapyCatherine C Park
Department of Radiation Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 1600 Divisadero St, H1031, San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 76:963-72. 2010..The full Emerging Technology Committee report is available on the American Society for Therapeutic Radiology and Oncology Web site... - Inverse planning for interstitial gynecologic template brachytherapy: truly anatomy-based planningEtienne Lessard
Department of Radiation Oncology, University of California San Francisco, 1600 Divisadero Street, Suite H1031, San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 54:1243-51. 2002..The objective of this work is to present the clinical application of an inverse planning dose optimization tool for the automatic determination of source dwell time values in the treatment of interstitial gynecologic templates... - Image-guided radiotherapy using megavoltage cone-beam computed tomography for treatment of paraspinous tumors in the presence of orthopedic hardwareEric K Hansen
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94115, USA
Int J Radiat Oncol Biol Phys 66:323-6. 2006.... - The effect of the radial function on I-125 seeds used for permanent prostate implantationBarby Pickett
Department of Radiation Oncology, University of California San Francisco UCSF, San Francisco, CA, USA
Med Dosim 29:204-9. 2004..It was determined that the dose rate constant and anisotropy factor determine the activity needed for implantation but a strong dependence on the radial function was found to effect the doses to the adjacent structures... - 3D inverse treatment planning for the tandem and ovoid applicator in cervical cancerKelly D Dewitt
Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA 94143-170, USA
Int J Radiat Oncol Biol Phys 63:1270-4. 2005..Image-guided brachytherapy and inverse planning improve brachytherapy dosimetry... - Does IGRT ensure target dose coverage of head and neck IMRT patients?Pierre Graff
Department of Radiation Oncology, University of California San Francisco, CA 94143, USA
Radiother Oncol 104:83-90. 2012..To determine if image-guided radiotherapy (IGRT) ensures dose coverage to the target, and to assess the dosimetric impact of anatomic changes using megavoltage cone-beam CT (MVCBCT) for patient positioning during head and neck IMRT... - NPIP: A skew line needle configuration optimization system for HDR brachytherapyTimmy Siauw
Department of Civil and Environmental Engineering, University of California, Berkeley, CA, USA
Med Phys 39:4339-46. 2012..NPIP generates needle configurations that are specific to the anatomy of the patient, avoid critical structures near the penile bulb and other healthy structures, and avoid needle collisions inside the body... - Calibration of an amorphous-silicon flat panel portal imager for exit-beam dosimetryJosephine Chen
Department of Radiation Oncology, UCSF Comprehensive Cancer Center, 1600 Divisadero Street, Suite H1031, San Francisco, CA 94115, USA
Med Phys 33:584-94. 2006..This calibration method for flat panel portal imagers may be used as part of a validation scheme to verify the dose delivered to the patient during treatment... - Megavoltage cone-beam CT: system description and clinical applicationsOlivier Morin
University of California San Francisco Comprehensive Cancer Center, Department of Radiation Oncology, 94143, USA
Med Dosim 31:51-61. 2006..Current image quality has already proven sufficient for many IGRT applications. Moreover, we expect the range of clinical applications for MV CBCT to grow as imaging technology continues to improve... - Urethra low-dose tunnels: validation of and class solution for generating urethra-sparing dose plans using inverse planning simulated annealing for prostate high-dose-rate brachytherapyJ Adam M Cunha
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94118, USA
Brachytherapy 11:348-53. 2012..This work describes a dose planning method that uses inverse planning to create a low-dose tunnel around the urethra and presents a class solution to achieve this additional dose sparing of the urethra... - Correction of megavoltage cone-beam CT images for dose calculation in the head and neck regionJean Francois Aubry
Department of Radiation Oncology, University of California San Francisco, 1600 Divisadero Street, Suite H1031, San Francisco, California 94143, USA
Med Phys 35:900-7. 2008..With patients images the agreement is within +/- 13% above the shoulders and +/- 5% below the shoulder line. This level of dose calculation accuracy allows the use of MVCBCT images for dose verification purposes... - Target localization and real-time tracking using the Calypso 4D localization system in patients with localized prostate cancerTwyla R Willoughby
Department of Radiation Oncology, M.D. Anderson Cancer Center Orlando, Orlando, FL 32806, USA
Int J Radiat Oncol Biol Phys 65:528-34. 2006..Clinical evaluation of this novel 4D nonionizing electromagnetic localization system with transponders indicates a comparable localization accuracy to isocenter, (within 2 mm) compared with X-ray localization... - Phase I trial of gross total resection, permanent iodine-125 brachytherapy, and hyperfractionated radiotherapy for newly diagnosed glioblastoma multiformeAllen M Chen
Department of Radiation Oncology, University of California, San Francisco School of Medicine, San Francisco, CA 94143 0226, USA
Int J Radiat Oncol Biol Phys 69:825-30. 2007..To evaluate the feasibility of gross total resection and permanent I-125 brachytherapy followed by hyperfractionated radiotherapy for patients with newly diagnosed glioblastoma... - Inverse-planned modulated-arc total-body irradiationNeil Kirby
Department of Radiation Oncology, University of California, San Francisco, CA, USA
Med Phys 39:2761-4. 2012.... - American Brachytherapy Society consensus guidelines for high-dose-rate prostate brachytherapyYoshiya Yamada
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Brachytherapy 11:20-32. 2012..Most of the articles describe HDR as a boost with adjuvant external beam radiation, but there is a growing experience with HDR monotherapy... - Optimisation-based thermal treatment planning for catheter-based ultrasound hyperthermiaXin Chen
Thermal Therapy Research Group, Department of Radiation Oncology, University of California at San Francisco, San Francisco, California 94143 1708, USA
Int J Hyperthermia 26:39-55. 2010.... - Automated seed detection and three-dimensional reconstruction. II. Reconstruction of permanent prostate implants using simulated annealingD Tubic
Department of Radiation Oncology, Centre Hospitalier Universitaire de Quebec, l'Universite Laval, 11 Cote du Palais, Quebec GIR 2J6, Canada
Med Phys 28:2272-9. 2001..Compared to the latter technique, the reconstruction precision was improved in 62% of the clinical cases... - Characteristics of megavoltage cone-beam digital tomosynthesisM Descovich
Department of Radiation Oncology, University of California at San Francisco, San Francisco, California 94143 0226, USA
Med Phys 35:1310-6. 2008..Potential clinical applications include patient setup and the development of breath holding techniques for gated imaging... - Dosimetric equivalence of nonstandard HDR brachytherapy catheter patternsJ A M Cunha
University of California, San Francisco, California 94115, USA
Med Phys 36:233-9. 2009..To determine whether alternative high dose rate prostate brachytherapy catheter patterns can result in similar or improved dose distributions while providing better access and reducing trauma... - Inverse planning anatomy-based dose optimization for HDR-brachytherapy of the prostate using fast simulated annealing algorithm and dedicated objective functionE Lessard
Service de radio oncologie, L Hôtel Dieu de Québec, Centre Hospitalier Universitaire de Quebec CHUQ, Centre de recherche en cancérologie de l Université Laval, Canada
Med Phys 28:773-9. 2001..Moreover, using the same concept, it will be possible to deliver a boost dose to a delimited tumor volume within the prostate. Finally, this method can be easily extended to other anatomical sites... - Evaluation of ultrasound-based prostate localization for image-guided radiotherapyK M Langen
Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA 94143, USA
Int J Radiat Oncol Biol Phys 57:635-44. 2003..However, the occurrence of displacements >/=5 mm was reduced in the AP direction. The inter-user variation of the contour alignment process was significant... - Relative biological effectiveness enhancement of a 125I brachytherapy seed with characteristic x rays from its constitutive materialsRichard Taschereau
Centre Hospitalier Universitaire de Quebec, Département de Radio Oncologie, Canada
Med Phys 29:1397-402. 2002..The RBE dependence on distance is an interesting feature that could benefit other applications such as ocular melanoma or coronary brachytherapy where a highly localized dose distribution is desired... - A comparison of methods to calculate biological effectiveness (RBE) from Monte Carlo simulationsRichard Taschereau
Centre Hospitalier Universitaire de Quebec, Quebec, Canada
Med Dosim 28:21-6. 2003..The former yields a value of 10.6%, twice the value obtained with the latter (4.5%). Which spectrum to use is an open question. A theoretical argument is presented in favor of the ejection spectrum... - A spatially encoded dose difference maximal intensity projection map for patient dose evaluation: a new first line patient quality assurance toolWeigang Hu
Department of Radiation Oncology, University of California, San Francisco, San Francisco, California 94143, USA
Med Phys 38:1748-53. 2011..To develop a spatially encoded dose difference maximal intensity projection (DD-MIP) as an online patient dose evaluation tool for visualizing the dose differences between the planning dose and dose on the treatment day... - A comparison between tandem and ovoids and interstitial gynecologic template brachytherapy dosimetry using a hypothetical computer modelI Chow J Hsu
Department of Radiation Oncology, University of California at San Francisco, San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 52:538-43. 2002..To evaluate the dose distribution within the clinical target volume between two gynecologic brachytherapy systems---the tandem and ovoids and the Syed-Neblett gynecologic template---using a hypothetical computer model... - A two-dimensional deformable phantom for quantitatively verifying deformation algorithmsNeil Kirby
Department of Radiation Oncology, University of California San Francisco, San Francisco, California 94143 1708, USA
Med Phys 38:4583-6. 2011..This manuscript proposes a two-dimensional deformable phantom, which can objectively verify the accuracy of deformation algorithms, as the next step for improving these techniques... - Automated seed detection and three-dimensional reconstruction. I. Seed localization from fluoroscopic images or radiographsD Tubic
Department of Radiation Oncology, , , Canada
Med Phys 28:2265-71. 2001..The orientation of overlapping seeds (10%) should be considered as an estimate at best. The image processing procedure can also be used for seed or catheter detection in CT images, with minor modifications... - Dose-guided radiation therapy with megavoltage cone-beam CTJ Chen
UCSF Comprehensive Cancer Center, Department of Radiation Oncology, University of California San Francisco, 1600 Divisadero Street, Suite H1031, San Francisco, CA 94143, USA
Br J Radiol 79:S87-98. 2006..We also present an example of a reconstructed patient dose using a preliminary reconstruction program and discuss the technical challenges that remain to full implementation of dose reconstruction and dose-guided therapy... - The need for application-based adaptation of deformable image registrationNeil Kirby
Department of Radiation Oncology, University of California San Francisco, California 94143 1708
Med Phys 40:011702. 2013..For this reason, these algorithms must be tested for their overall spatial accuracy. The developed phantom is an objective tool for this purpose... - The use of megavoltage cone-beam CT to complement CT for target definition in pelvic radiotherapy in the presence of hip replacementM Aubin
Department of Radiation Oncology, University of California San Francisco, Comprehensive Cancer Center, San Francisco, CA 94143, USA
Br J Radiol 79:918-21. 2006..This short communication presents the use of a new imaging modality, megavoltage cone-beam CT, to complement the regular CT for target definition of prostate cancer treatment of patients with hip replacements... - Quality assurance for image-guided radiation therapy utilizing CT-based technologies: a report of the AAPM TG-179Jean Pierre Bissonnette
Department of Radiation Physics, University of Toronto, Toronto, Ontario, Canada
Med Phys 39:1946-63. 2012..This document provides consensus recommendations for quality assurance protocols that ensure patient safety and patient treatment fidelity for such systems... - Adapting liver motion models using a navigator channel techniqueT N Nguyen
Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 3E2, Canada
Med Phys 36:1061-73. 2009..This method has potential applications in online assessment of motion at the time of treatment to improve image-guided radiotherapy and monitoring of intrafraction motion... - Characterization of a fluoroscopic imaging system for kV and MV radiographyD G Drake
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
Med Phys 27:898-905. 2000..This is attributed to the kV system's higher DQE and to the inherently higher contrasts present at kV energies... - Cone-beam computed tomography with a flat-panel imager: initial performance characterizationD A Jaffray
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
Med Phys 27:1311-23. 2000..General and specific requirements of kilovoltage CBCT systems are discussed, and the applicability of FPI-based CBCT systems to tomographic localization and image-guidance for radiotherapy is considered... - Improvement in dose escalation using the process of adaptive radiotherapy combined with three-dimensional conformal or intensity-modulated beams for prostate cancerA A Martinez
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48073, USA
Int J Radiat Oncol Biol Phys 50:1226-34. 2001..The potential dose escalation achievable with this ART process is quantified for both conformal radiotherapy (CRT) delivery and intensity-modulated radiotherapy (IMRT) delivery... - The use of active breathing control (ABC) to reduce margin for breathing motionJ W Wong
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48073 6769, USA
Int J Radiat Oncol Biol Phys 44:911-9. 1999..Treatment planning and delivery can then be performed at identical ABC conditions with minimal margin for breathing motion... - A framework for noise-power spectrum analysis of multidimensional imagesJ H Siewerdsen
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
Med Phys 29:2655-71. 2002..The framework may be applied to NPS analysis of image data of arbitrary dimensionality provided the system satisfies conditions of NPS existence... - A two isocenter IMRT technique with a controlled junction dose for long volume targetsG G Zeng
Radiation Medicine Program, Princess Margaret Hospital University Health Network, Toronto M5G 2M9, Canada
Phys Med Biol 52:4541-52. 2007..Film measurements confirmed the treatment planning results... - Intra-prostatic fiducial markers and concurrent androgen deprivationA M Nichol
Radiation Medicine Program, Princess Margaret Hospital, Toronto, Canada
Clin Oncol (R Coll Radiol) 17:465-8. 2005..With concurrent androgen deprivation, daily on-line set-up correction to fiducial markers can aid in safe dose escalation... - A ghost story: spatio-temporal response characteristics of an indirect-detection flat-panel imagerJ H Siewerdsen
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073 6769, USA
Med Phys 26:1624-41. 1999..g., rapid scanning between projections or iterative correction algorithms, respectively). Similarly, long-term image persistence may necessitate frequent recalibration of offset corrections... - Dose-volume analysis for quality assurance of interstitial brachytherapy for breast cancerF A Vicini
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48073, USA
Int J Radiat Oncol Biol Phys 45:803-10. 1999..Analyses performed in this fashion will be needed to ultimately assist in determining the efficacy of breast implants... - Cone-beam computed tomography with a flat-panel imager: effects of image lagJ H Siewerdsen
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
Med Phys 26:2635-47. 1999..The artifacts may become appreciable, however, in the presence of high-contrast objects, such as marker BBs, dental fillings, and metal prosthetics. A procedural method of reducing lag artifacts is demonstrated... - Implementation and characterization of a 320-slice volumetric CT scanner for simulation in radiation oncologyC Coolens
Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario M5G 2M9, Canada
Med Phys 36:5120-7. 2009..The aim of this work is to investigate the system's imaging performance and quality as well as CT quantification accuracy which is important for radiotherapy dose calculations... - Soft-tissue detectability in cone-beam CT: evaluation by 2AFC tests in relation to physical performance metricsD J Tward
Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
Med Phys 34:4459-71. 2007..g., image guidance tasks in which lesion characteristics are known) is maintained at a lower dose than in SUK conditions (e.g., diagnostic tasks in which lesion characteristics are unknown)... - High resolution gel-dosimetry by optical-CT and MR scanningM Oldham
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
Med Phys 28:1436-45. 2001.... - Optimization of x-ray imaging geometry (with specific application to flat-panel cone-beam computed tomography)J H Siewerdsen
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
Med Phys 27:1903-14. 2000..g., chest radiography, fluoroscopy, and mammography) is possible. The degree to which increased exposure can be used to compensate for x-ray scatter degradation is quantified... - Active breathing control (ABC) for Hodgkin's disease: reduction in normal tissue irradiation with deep inspiration and implications for treatmentJ S Stromberg
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48098, USA
Int J Radiat Oncol Biol Phys 48:797-806. 2000..Active breathing control (ABC) temporarily immobilizes breathing. This may allow a reduction in treatment margins. This planning study assesses normal tissue irradiation and reproducibility using ABC for Hodgkin's disease... - Cone-beam computed tomography with a flat-panel imager: magnitude and effects of x-ray scatterJ H Siewerdsen
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
Med Phys 28:220-31. 2001..Other reconstruction parameters, such as transaxial resolution length and reconstruction filter, can be similarly adjusted to achieve CNR equal to that obtained in the scatter-free case... - Volume CT with a flat-panel detector on a mobile, isocentric C-arm: pre-clinical investigation in guidance of minimally invasive surgeryJ H Siewerdsen
Ontario Cancer Institute, Princess Margaret Hospital, Toronto, Ontario M5G 2M9, Canada
Med Phys 32:241-54. 2005..Future investigation includes improvement in image quality, particularly regarding x-ray scatter, motion artifacts and field of view, and integration with optical tracking and navigation systems... - Dosimetric evaluation of a dedicated stereotactic linear accelerator using measurement and Monte Carlo simulationM Heydarian
Radiation Medicine Program, Princess Margaret Hospital and Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5G 2M9, Canada
Med Phys 35:3943-54. 2008..Film dosimetry was also used to compare dose distributions of IMRT treatment plans and delivered cumulative doses at different cross sectional planes...