Research Topics
| Robert PostonSummaryAffiliation: University of Maryland Country: USA Publications
Research Grants
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Detail Information
Publications
Endovascular stenting for traumatic aortic injury: an emerging new standard of careSina L Moainie
Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
Ann Thorac Surg 85:1625-9; discussion 1629-30. 2008..Thoracic aortic stents have the potential to treat aortic tears using a less invasive approach. We have accumulated the largest series of patients treated with blunt thoracic aortic injury over a 2-year period...- Comparison of economic and patient outcomes with minimally invasive versus traditional off-pump coronary artery bypass grafting techniquesRobert S Poston
Division of Cardiac Surgery, Boston University School of Medicine, Boston, MA 02114, USA
Ann Surg 248:638-46. 2008..We performed a prospective cohort study (NCT00481806) to assess the impact of miniCABG on costs and metrics that influence quality of life after hospital discharge... - The role of preexisting pathology in the development of neointimal hyperplasia in coronary artery bypass graftsZachary N Kon
Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
J Surg Res 142:351-6. 2007..The purpose of this cohort study was to investigate clinical risk factors for NH by monitoring luminal narrowing within SVG using multichannel CT angiography (CTA)... - Platelet function tests predict bleeding and thrombotic events after off-pump coronary bypass graftingRobert Poston
Division of Cardiac Surgery, Department of Surgery, School of Medicine, University of Maryland, N4W94 22 S Greene St, Baltimore, MD 21201, USA
Eur J Cardiothorac Surg 27:584-91. 2005..However, the best method to monitor this balance has not been established. We used a series of tests of coagulation and platelet function to define the risk of bleeding and thrombotic events after OPCAB... - Invited commentaryRobert Poston
Department of Surgery, Division of Cardiac Surgery, University of Maryland, N4W94 22 S Greene St, Baltimore, MD 21201, USA
Ann Thorac Surg 84:465-6. 2007 - Perioperative management of aspirin resistance after off-pump coronary artery bypass grafting: possible role for aprotininRobert S Poston
Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
Transfusion 48:39S-46S. 2008..The factors, mechanism, and best means for preventing and/or treating ASA-R have not been established. This study hypothesizes that thrombin production during OPCAB stimulates this acquired ASA-R... - Endothelial injury and acquired aspirin resistance as promoters of regional thrombin formation and early vein graft failure after coronary artery bypass graftingRobert S Poston
Department of Surgery, University of Maryland School of Medicine and Baltimore VAMC, Baltimore, MD, USA
J Thorac Cardiovasc Surg 131:122-30. 2006..We hypothesized that synergy between endothelial disruption in the venous conduit and aspirin resistance would cause vein graft failure... - Aprotinin shows both hemostatic and antithrombotic effects during off-pump coronary artery bypass graftingRobert S Poston
Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
Ann Thorac Surg 81:104-10; discussion 110-1. 2006..In a randomized, prospective OPCABG trial, we assessed efficacy and safety of aprotinin through a comprehensive assessment of graft patency and hematologic function... - Virchow triad, but not use of an aortic connector device, predicts early graft failure after off-pump coronary bypassRobert Poston
Division of Cardiac Surgery, University of Maryland, Baltimore, Maryland 21201, USA
Heart Surg Forum 7:E428-33. 2004..The perioperative combination of platelet hyperreactivity, marginal graft flow, and endothelial disease proved to be highly predictive of early graft failure as seen with postoperative computed tomographic angiography... - Heart transplantationRobert S Poston
University of Maryland, Baltimore, MD, USA
J Intensive Care Med 19:3-12. 2004..Surgical techniques and medical management have reduced the incidence of postoperative right heart failure, and immunosuppressive regimens promise to limit chronic graft vascular disease... - Optimizing donor heart outcome after prolonged storage with endothelial function analysis and continuous perfusionRobert S Poston
University of Maryland School of Medicine and Veterans Affairs Medical Center at Baltimore, Division of Cardiac Surgery, Baltimore, Maryland, USA
Ann Thorac Surg 78:1362-70;; discussion 1362-70. 2004..quot; My colleagues and I investigated whether an analysis of donor heart viability predicts recovery of grafts challenged with a 24-hour preservation interval... - Hypercoagulability affecting early vein graft patency does not exist after off-pump coronary artery bypassRobert Poston
Department of Surgery, Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA
J Cardiothorac Vasc Anesth 19:11-8. 2005.... - Impact of the learning curve for endoscopic vein harvest on conduit quality and early graft patencyPranjal Desai
Department of Surgery, University of Arizona, Tucson, AZ 85724 5071, USA
Ann Thorac Surg 91:1385-91; discussion 1391-2. 2011..To test whether the learning curve for EVH alters conduit integrity owing to increased trauma compared with an open harvest, we analyzed the quality and early patency of conduits procured by technicians with varying EVH experience... - Prospective, observational study of antiplatelet and coagulation biomarkers as predictors of thromboembolic events after implantation of ventricular assist devicesFarhan Majeed
Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD, USA
Nat Clin Pract Cardiovasc Med 6:147-57. 2009..We evaluated the predictive value of aspirin hyporesponsiveness and markers of coagulation and fibrinolysis... - Association between prothrombin activation fragment (F1.2), cerebral ischemia (S-100beta) and international normalized ratio (INR) in patients with ventricular assisted devicesAshish Joshi
Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Maryland 21201, USA
Interact Cardiovasc Thorac Surg 6:323-7. 2007..Further trials that incorporate the F1.2 marker into anticoagulation algorithms may help reduce adverse events in this high-risk population... - Simultaneous hybrid coronary revascularization reduces postoperative morbidity compared with results from conventional off-pump coronary artery bypassZachary N Kon
Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical System, Baltimore, MD 21201, USA
J Thorac Cardiovasc Surg 135:367-75. 2008..We hypothesized that stenting combined with grafting of the left anterior descending artery with the left internal thoracic artery through a minithoracotomy (hybrid procedure) would provide the best outcome... - Anticoagulant monitoring in ventricular assist device patients: a feasibility studyAshish Joshi
Department of Information Systems, University of Maryland, Baltimore County, Baltimore, MD 21201, USA
Interact Cardiovasc Thorac Surg 7:1035-8. 2008..Further research needs to be done to determine the impact of home INR monitoring and long-term health in these patients... - Is aprotinin safe to use in a cohort at increased risk for thrombotic events: results from a randomized, prospective trial in off-pump coronary artery bypassMichael C Grant
Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical System, Baltimore, Maryland, USA
Ann Thorac Surg 86:815-22; discussion 815-22. 2008..Our group previously demonstrated that off-pump coronary artery bypass (OPCAB) is linked to a postoperative hypercoagulable state. In this study, we tested whether aprotinin influences thrombotic events after OPCAB... - Disruption of graft endothelium correlates with early failure after off-pump coronary artery bypass surgeryJeffrey V Manchio
Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
Ann Thorac Surg 79:1991-8. 2005..A means to assess, prevent, and treat intraoperative vein graft damage will likely improve early graft patency... - Catheter-based infrared light scanner as a tool to assess conduit quality in coronary artery bypass surgeryNicholas Burris
Department of Cardiac Surgery, University of Maryland, School of Medicine, Baltimore, MD 21201, USA
J Thorac Cardiovasc Surg 133:419-27. 2007..We used a novel infrared imaging technology, optical coherence tomography (OCT; LightLab Imaging, Inc, Westford, Mass), to visualize the intima within harvested conduits... - Heart preservation using continuous ex vivo perfusion improves viability and functional recoveryToshinaga Ozeki
Division of Cardiac Surgery, University of Maryland School of Medicine and VA Medical Center at Baltimore 21201, USA
Circ J 71:153-9. 2007.... - Use of diffusion tensor imaging to predict myocardial viability after warm global ischemia: possible avenue for use of non-beating donor heartsMichael J Collins
Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical System, Baltimore, Maryland 21201, USA
J Heart Lung Transplant 26:376-83. 2007.... - Cardiac CT angiography after coronary bypass surgery: prevalence of incidental findingsJeffrey Mueller
Department of Diagnostic Radiology, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, USA
AJR Am J Roentgenol 189:414-9. 2007..The purpose of our study was to retrospectively assess the prevalence of unsuspected disease identified on cardiac CTA examinations after CABG and to determine their potential clinical significance... - Warm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibitionZachary N Kon
Department of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD, United States
Eur J Cardiothorac Surg 33:215-21. 2008..We hypothesized that regional myocardial ischemia caused by obligatory periods of coronary occlusion during OPCAB is an important trigger for this prothrombotic state... - Simultaneous "hybrid" percutaneous coronary intervention and minimally invasive surgical bypass grafting: feasibility, safety, and clinical outcomesBarry Reicher
Division of Cardiology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
Am Heart J 155:661-7. 2008.... - A multi-institutional experience with the CryoMaze procedureJames S Gammie
Division of Cardiac Surgery, University of Maryland Medical Center, Baltimore, MD 21201, USA
Ann Thorac Surg 80:876-80; discussion 880. 2005..We report our experience using a flexible argon-powered metal cryoprobe for creation of the complete Cox-Maze III lesion set in patients with AF (the CryoMaze operation)... - Coronary artery bypass grafts: assessment with multidetector CT in the early and late postoperative settingsAletta Ann Frazier
Department of Diagnostic Imaging, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, USA
Radiographics 25:881-96. 2005..In addition, the expanded capabilities of volumetric imaging may provide valuable information in preoperative planning for repeat CABG surgery... - A novel approach to tricuspid valve replacement: the upside down stentless aortic bioprosthesisMarcelo G Cardarelli
Division of Cardiac Surgery, University of Maryland Medical System, Baltimore, Maryland 21201, USA
Ann Thorac Surg 80:507-10. 2005..Choices between mechanical and biological prosthesis still generate controversy. We present our initial clinical experience with a stentless aortic root placed inverted in the tricuspid annulus... - Off-pump versus on-pump coronary artery bypass grafting in consecutive patients: decision-making algorithm and outcomesJames M Brown
Division of Cardiac Surgery, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
Ann Thorac Surg 81:555-61; discussion 561. 2006..Our analysis presents this decision algorithm and describes outcomes using this approach... - Aortic valve bypass for the high-risk patient with aortic stenosisJames S Gammie
Division of Cardiac Surgery, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
Ann Thorac Surg 81:1605-10. 2006..We have undertaken a programmatic effort to perform aortic valve bypass surgery as an alternative to conventional aortic valve replacement in selected high-risk patients, and now report our recent experience... - A hybrid alternative for high risk left main diseaseDavid Zimrin
Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
Catheter Cardiovasc Interv 69:123-7. 2007.... - Optical coherence tomography imaging as a quality assurance tool for evaluating endoscopic harvest of the radial arteryNicholas S Burris
Department of Surgery, University of Maryland, Baltimore, Maryland 21201, USA
Ann Thorac Surg 85:1271-7. 2008..Radial artery conduits were screened intraoperatively before and after ERAH vs open harvest using catheter-based high-resolution optical coherence tomography (OCT) imaging... - Preserving and evaluating hearts with ex vivo machine perfusion: an avenue to improve early graft performance and expand the donor poolMichael J Collins
Division of Cardiac Surgery, Department of Surgery, University of Maryland Medical Center, 22 S Greene Street, Baltimore, MD 21201, USA
Eur J Cardiothorac Surg 34:318-25. 2008.... - Intraoperative detection of intimal lipid in the radial artery predicts degree of postoperative spasmEmile N Brown
University of Maryland School of Medicine, Department of Surgery, Baltimore, United States
Atherosclerosis 205:466-71. 2009..We imaged RA conduits before and after CABG in order to characterize intimal abnormalities that might relate to the risk of spasm... - Establishing the case for minimally invasive, robotic-assisted CABG in the treatment of multivessel coronary artery diseaseBrandon Jones
Division of Cardiac Surgery, Boston University School of Medicine, Boston, MA 02118, USA
Heart Surg Forum 12:E147-9. 2009..Arguments for continued procedure development in robotically assisted CABG are provided... - The influence of fat thickness on the human epicardial bipolar electrogram characteristics: measurements on patients undergoing open-heart surgeryMagdi M Saba
Department of Medicine, University of Maryland, Cardiac Electrophysiology Service, 22 South Greene Street, Room N3W77, Baltimore, MD 21201, USA
Europace 11:949-53. 2009..We sought to establish such values for EPI electrogram voltage, including areas with overlying fat... - Myocardial reperfusion injury: etiology, mechanisms, and therapiesJohn W Hoffman
Towson University, Towson, Maryland, USA
J Extra Corpor Technol 36:391-411. 2004..Effective treatment will most likely require multifaceted antagonism of the numerous pathological cascades initiated by reperfusion... - Strategies to reduce intraluminal clot formation in endoscopically harvested saphenous veinsEmile N Brown
Department of Surgery, Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA
J Thorac Cardiovasc Surg 134:1259-65. 2007..We hypothesized that endoscopic visualization facilitated by sealed carbon dioxide insufflation causes stagnation of blood within the saphenous vein. In the absence of prior heparin administration, this stasis provokes clot formation... - Thinking inside the graft: applications of optical coherence tomography in coronary artery bypass graftingEmile N Brown
University of Maryland, School of Medicine, Department of Cardiac Surgery, 22 South Greene Street N4W94, Baltimore, Maryland 21201, USA
J Biomed Opt 12:051704. 2007..We demonstrate the feasibility of OCT imaging as an intraoperative tool to select conduit vessels for CABG... - Harmonic scalpel versus electrocautery for harvest of radial artery conduits: reduced risk of spasm and intimal injury on optical coherence tomographyPhilip S Brazio
Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD, USA
J Thorac Cardiovasc Surg 136:1302-8. 2008.... - LVAD bloodstream infections: therapeutic rationale for transplantation after LVAD infectionRobert S Poston
Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
J Heart Lung Transplant 22:914-21. 2003..However, an extra-device source of BSI should be excluded by considering the isolated organism, the baseline nutritional status, and other risk factors... - Blood product transfusion in association with coronary artery bypass grafting: proceed with cautionDebra L Malone
Crit Care Med 34:1823-4. 2006 - Letter by Landis et al regarding article "Aprotinin does not increase the risk of renal failure in cardiac surgery patients"R Clive Landis
Circulation 117:e473; author reply e476. 2008
Research Grants
- Thrombin dysregulation leads to early saphenous vein graft failureRobert Poston; Fiscal Year: 2007....