Katherine L Possin
Affiliation: University of California
- Dissociable executive functions in behavioral variant frontotemporal and Alzheimer dementiasKatherine L Possin
From the Department of Neurology K L P, D F, K P R, A L B, K W, B L M, J H K, Memory and Aging Center, University of California, San Francisco and Mayo Clinic G E S, S M H, Rochester, MN
Neurology 80:2180-5. 2013..The objective of this study was to determine which aspects of executive functions are most affected in behavioral variant frontotemporal dementia (bvFTD) and best differentiate this syndrome from Alzheimer disease (AD)...
- The frontal-anatomic specificity of design fluency repetitions and their diagnostic relevance for behavioral variant frontotemporal dementiaKatherine L Possin
Department of Neurology, University of California, San Francisco, San Francisco, California 94143 1207, USA
J Int Neuropsychol Soc 18:834-44. 2012..These results highlight the frontal-anatomic specificity of design fluency repetitions. In addition, the results indicate that the propensity to make these errors supports the diagnosis of bvFTD. (JINS, 2012, 18, 1-11)...
- Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementiaKatherine L Possin
University of California, 350 Parnassus Ste 905, San Francisco, CA 94143 1207, United States
Neuropsychologia 49:43-8. 2011..Alternative methods of visual spatial assessment for dementia evaluations are proposed...
- Visual spatial cognition in neurodegenerative diseaseKatherine L Possin
Department of Neurology, University of California, San Francisco, CA, USA
Neurocase 16:466-87. 2010..Visual spatial cognition will be organized primarily according to the following schemes: bottom-up/top-down processing, dorsal/ventral stream processing, and egocentric/allocentric frames of reference...
- Rule violation errors are associated with right lateral prefrontal cortex atrophy in neurodegenerative diseaseKatherine L Possin
Department of Neurology, University of California San Francisco, San Francisco, California, USA
J Int Neuropsychol Soc 15:354-64. 2009..These data underscore the importance of right lateral PFC in behavioral monitoring and highlight the potential of RV error assessment for identifying patients with damage to this region...
- Space-based but not object-based inhibition of return is impaired in Parkinson's diseaseKatherine L Possin
Department of Psychiatry, University of California, San Diego, United States
Neuropsychologia 47:1694-700. 2009..This dissociation supports the view that space-based and object-based components of attention involve distinct neurocognitive processes...
- Spatial and object working memory deficits in Parkinson's disease are due to impairment in different underlying processesKatherine L Possin
University of California, San Diego, CA, USA
Neuropsychology 22:585-95. 2008..These results suggest that deficits in working memory for spatial and object information are mediated by distinct cognitive processes in nondemented patients with PD and may differ in their pathophysiological basis...
- The ubiquity of memory retrieval deficits in patients with frontal-striatal dysfunctionVanessa S Zizak
University of California, San Diego, CA 92161, USA
Cogn Behav Neurol 18:198-205. 2005..In this study, we examined the ubiquity of this "retrieval deficit" profile in a relatively large sample of patients with Parkinson disease (PD) or Huntington disease (HD)...
- Atrophy in two attention networks is associated with performance on a Flanker task in neurodegenerative diseaseTracy L Luks
Department of Radiology and Biomedical Imaging, University of California San Francisco, CA 94143, USA
Neuropsychologia 48:165-70. 2010....
- Gray matter correlates of set-shifting among neurodegenerative disease, mild cognitive impairment, and healthy older adultsJudy Pa
Alzheimer Disease Research Center, Dept of Neurology, University of California, San Francisco, California, USA
J Int Neuropsychol Soc 16:640-50. 2010..Overall, these findings highlight the neuroanatomical correlates of set-shifting and the importance of controlling for component processes when investigating complex cognitive tasks...
- White matter atrophy in Alzheimer's disease variantsRaffaella Migliaccio
Memory and Aging Center, Department of Neurology, University of California at San Francisco, San Francisco, CA, USA
Alzheimers Dement 8:S78-87.e1-2. 2012..Severe hemispheric gray matter (GM) atrophy associated with EOAD, lv-PPA, and PCA has been described, but regional patterns of white matter (WM) damage are still poorly understood...
- Is a perseveration a perseveration? An evaluation of cognitive error types in patients with subcortical pathologyKatherine L Possin
SDSU UCSD Joint Doctoral Program in Clinical Psychology, San Diego, CA 92109, USA
J Clin Exp Neuropsychol 27:953-66. 2005....
- Apolipoprotein E epsilon4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementiaFederica Agosta
Memory and Aging Center, Department of Neurology, University of California, 350 Parnassus Avenue, Suite 905, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 106:2018-22. 2009..The atrophy patterns in epsilon4 carriers may indicate that they are at greater risk for clinical progression...
- The early neuropsychological and behavioral characteristics of frontotemporal dementiaDana Wittenberg
Memory and Aging Center, University of California San Francisco Medical Center, San Francisco, CA, USA
Neuropsychol Rev 18:91-102. 2008..As this review underscores, frontotemporal dementia remains a powerful model for studying brain-behavior relationships...
- Regional alterations of brain microstructure in Parkinson's disease using diffusion tensor imagingWang Zhan
Department of Radiology and Medical Imaging, Center of Imaging for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, California, USA
Mov Disord 27:90-7. 2012..Our data suggest that microstructural alterations detected with diffusion tensor might serve as a potential biomarker for PD...
- Symptoms of frontotemporal dementia provide insights into orbitofrontal cortex function and social behaviorIndre V Viskontas
Memory and Aging Center, Department of Neurology, University of California, San Francisco, Avenue, San Francisco, CA 94143 1207, USA
Ann N Y Acad Sci 1121:528-45. 2007..Here, we review the behavioral and neuropsychological changes that accompany OFC atrophy in FTD and argue that phylogenetically new neurons found in this region, called von Economo neurons, are selectively vulnerable in FTD...
- Lack of impairment in patients with Parkinson's disease on an object-based negative priming taskKatherine L Possin
SDSU UCSD Joint Doctoral Program in Clinical Psychology, USA
Percept Mot Skills 102:219-30. 2006..These results suggest that certain object-based attentional processes may not be impaired in patients with Parkinson's disease...