- Single-step conversion of P1 and P1 artificial chromosome clones into yeast artificial chromosomesP Poorkaj
Geriatric Research Education Clinical Center, Seattle, Washington 98108, USA
Genomics 68:106-10. 2000..The resulting YAC can be used for generating transgenic animals and stably transfected cell lines. Also, the lys2 marker facilitates introduction of mutations by homologous recombination...
- Parkin mutation dosage and the phenomenon of anticipation: a molecular genetic study of familial parkinsonismParvoneh Poorkaj
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, USA
BMC Neurol 5:4. 2005..A subset of familial PD exhibits anticipation, the cause of which is unknown. The aim of this study was to determine if anticipation was due to parkin mutation dosage...