Research Topics
| John E PoolSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
The impact of founder events on chromosomal variability in multiply mating speciesJohn E Pool
Department of Integrative Biology, University of California, Berkeley, USA
Mol Biol Evol 25:1728-36. 2008..Investigating the potential of this process to account for sharply reduced X-linked diversity in European Drosophila melanogaster, we find that this model yields predictions that are compatible with the empirical data...
Inference of historical changes in migration rate from the lengths of migrant tractsJohn E Pool
Department of Statistics, University of California, Berkeley, California 94720, USA
Genetics 181:711-9. 2009..m. musculus, we find evidence for an increase in the rate of hybridization. Our findings could indicate an evolutionary trajectory toward fusion rather than speciation in these taxa...
Population genetic inference from genomic sequence variationJohn E Pool
Department of Integrative Biology, University of California, Berkeley, Berkeley, California 94720, USA
Genome Res 20:291-300. 2010..Here, we assess the challenges to analyzing whole-genome sequence polymorphism data, and we discuss the potential of these data to yield new insights concerning population history and the genomic prevalence of natural selection...
A scan of molecular variation leads to the narrow localization of a selective sweep affecting both Afrotropical and cosmopolitan populations of Drosophila melanogasterJohn E Pool
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
Genetics 172:1093-105. 2006..This pattern appears consistent with the demographic amplification of preexisting sweep signals due to one or more population bottlenecks...
History and structure of sub-Saharan populations of Drosophila melanogasterJohn E Pool
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
Genetics 174:915-29. 2006..melanogaster might have come from this region. Finally, we find a large excess of singleton polymorphisms in the full data set, which is best explained by a combination of population growth and purifying selection...
The genetic basis of adaptive pigmentation variation in Drosophila melanogasterJohn E Pool
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
Mol Ecol 16:2844-51. 2007..5 kb upstream of the protein-coding exons of ebony. Thus, natural selection may have elevated the frequency of an allele that confers dark abdominal pigmentation by influencing the regulation of ebony...
Population size changes reshape genomic patterns of diversityJohn E Pool
Centre for Comparative Genomics, Institute of Biology, University of Copenhagen, 2100 Copenhagen, Denmark
Evolution 61:3001-6. 2007..Consideration of this effect may improve the inference of population history and other evolutionary processes...
