Ovide Pomerleau

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Endogenous opioids and smoking: a review of progress and problems
    O F Pomerleau
    Department of Psychiatry, University of Michigan, Ann Arbor 48108, USA
    Psychoneuroendocrinology 23:115-30. 1998
  2. ncbi request reprint Genome-wide linkage analysis for smoking-related regions, with replication in two ethnically diverse populations
    Ovide F Pomerleau
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI 48105, USA
    Nicotine Tob Res 9:955-8. 2007
  3. ncbi request reprint Genetic research on complex behaviors: an examination of attempts to identify genes for smoking
    Ovide F Pomerleau
    Nicotine Research Laboratory, Department of Psychiatry, University of Michigan, Ann Arbor, MI 48105, USA
    Nicotine Tob Res 9:883-901. 2007
  4. ncbi request reprint Nicotine dependence, depression, and gender: characterizing phenotypes based on withdrawal discomfort, response to smoking, and ability to abstain
    Ovide F Pomerleau
    Nicotine Research Laboratory, University of Michigan Department of Psychiatry, Ann Arbor, MI 48105, USA
    Nicotine Tob Res 7:91-102. 2005
  5. ncbi request reprint Validation of retrospective reports of early experiences with smoking
    Ovide F Pomerleau
    Nicotine Research Laboratory, Department of Psychiatry, University of Michigan, 2025 Traverwood Drive, Ste B, Ann Arbor, MI 48108, USA
    Addict Behav 30:607-11. 2005
  6. ncbi request reprint Depression, smoking abstinence and HPA function in women smokers
    Ovide F Pomerleau
    Department of Psychiatry, Nicotine Research Laboratory, University of Michigan, Ann Arbor, MI 48105, USA
    Hum Psychopharmacol 19:467-76. 2004
  7. ncbi request reprint Development and validation of a self-rating scale for positive- and negative-reinforcement smoking: The Michigan Nicotine Reinforcement Questionnaire
    Ovide F Pomerleau
    Nicotine Research Laboratory, University of Michigan, Ann Arbor, MI 48108, USA
    Nicotine Tob Res 5:711-8. 2003
  8. pmc Substance use, trait measures, and subjective response to nicotine in never-smokers stratified on parental smoking history and sex
    Ovide F Pomerleau
    Department of Psychiatry, University of Michigan Medical School, Rachel Upjohn Building, Room 2137, Ann Arbor, MI 48105, USA
    Nicotine Tob Res 11:1055-66. 2009
  9. ncbi request reprint Early experiences with tobacco among women smokers, ex-smokers, and never-smokers
    O F Pomerleau
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, USA
    Addiction 93:595-9. 1998
  10. ncbi request reprint Abstinence effects and reactivity to nicotine during 11 days of smoking deprivation
    O F Pomerleau
    Nicotine Research Laboratory, University of Michigan Department of Psychiatry, Ann Arbor 48108, USA
    Nicotine Tob Res 2:149-57. 2000

Research Grants

  1. DIFFERENTIATION OF PHENOTYPES FOR SMOKING
    Ovide Pomerleau; Fiscal Year: 2003
  2. Effects of family smoking history in never-smokers
    Ovide Pomerleau; Fiscal Year: 2006
  3. CORTICOSTEROIDS, STRESS, AND NICOTINE DEPENDENCE
    Ovide Pomerleau; Fiscal Year: 1992
  4. DIFFERENTIATION OF PHENOTYPES FOR SMOKING
    Ovide Pomerleau; Fiscal Year: 1999
  5. Candidate Genes for Smoking In Related and Unrelated Individuals
    Ovide Pomerleau; Fiscal Year: 2007

Detail Information

Publications29

  1. ncbi request reprint Endogenous opioids and smoking: a review of progress and problems
    O F Pomerleau
    Department of Psychiatry, University of Michigan, Ann Arbor 48108, USA
    Psychoneuroendocrinology 23:115-30. 1998
    ..Taking these considerations into account should allow studies on endogenous opioid effects to begin to do justice to the complexity of both smoking behavior and the actions of nicotine...
  2. ncbi request reprint Genome-wide linkage analysis for smoking-related regions, with replication in two ethnically diverse populations
    Ovide F Pomerleau
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI 48105, USA
    Nicotine Tob Res 9:955-8. 2007
    ..Fine mapping may well provide useful new information about genetic factors underlying nicotine dependence...
  3. ncbi request reprint Genetic research on complex behaviors: an examination of attempts to identify genes for smoking
    Ovide F Pomerleau
    Nicotine Research Laboratory, Department of Psychiatry, University of Michigan, Ann Arbor, MI 48105, USA
    Nicotine Tob Res 9:883-901. 2007
    ..These proceedings are excerpts based on the presentations at the conference...
  4. ncbi request reprint Nicotine dependence, depression, and gender: characterizing phenotypes based on withdrawal discomfort, response to smoking, and ability to abstain
    Ovide F Pomerleau
    Nicotine Research Laboratory, University of Michigan Department of Psychiatry, Ann Arbor, MI 48105, USA
    Nicotine Tob Res 7:91-102. 2005
    ..These findings provide support for the existence of phenotypes that can be distinguished by withdrawal symptomatology (primarily driven by depression) and ability to remain abstinent (primarily driven by dependence)...
  5. ncbi request reprint Validation of retrospective reports of early experiences with smoking
    Ovide F Pomerleau
    Nicotine Research Laboratory, Department of Psychiatry, University of Michigan, 2025 Traverwood Drive, Ste B, Ann Arbor, MI 48108, USA
    Addict Behav 30:607-11. 2005
    ..To the extent that several days' abstinence can serve as a model for initial sensitivity to nicotine, our findings validate retrospective reports of pleasurable sensations upon early smoking experimentation...
  6. ncbi request reprint Depression, smoking abstinence and HPA function in women smokers
    Ovide F Pomerleau
    Department of Psychiatry, Nicotine Research Laboratory, University of Michigan, Ann Arbor, MI 48105, USA
    Hum Psychopharmacol 19:467-76. 2004
    ....
  7. ncbi request reprint Development and validation of a self-rating scale for positive- and negative-reinforcement smoking: The Michigan Nicotine Reinforcement Questionnaire
    Ovide F Pomerleau
    Nicotine Research Laboratory, University of Michigan, Ann Arbor, MI 48108, USA
    Nicotine Tob Res 5:711-8. 2003
    ..The M-NRQ has potential as a diagnostic tool for individualizing behavioral intervention and pharmacotherapy and also may be useful in identifying new phenotypes for genetic research on smoking...
  8. pmc Substance use, trait measures, and subjective response to nicotine in never-smokers stratified on parental smoking history and sex
    Ovide F Pomerleau
    Department of Psychiatry, University of Michigan Medical School, Rachel Upjohn Building, Room 2137, Ann Arbor, MI 48105, USA
    Nicotine Tob Res 11:1055-66. 2009
    ..Male and female never-smokers stratified on parental history of smoking were tested for possible differences in susceptibility to the hedonic effects of nicotine...
  9. ncbi request reprint Early experiences with tobacco among women smokers, ex-smokers, and never-smokers
    O F Pomerleau
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, USA
    Addiction 93:595-9. 1998
    ..Recent research suggests that people who become smokers may be more sensitive to the positive effects of nicotine than those who do not take up smoking...
  10. ncbi request reprint Abstinence effects and reactivity to nicotine during 11 days of smoking deprivation
    O F Pomerleau
    Nicotine Research Laboratory, University of Michigan Department of Psychiatry, Ann Arbor 48108, USA
    Nicotine Tob Res 2:149-57. 2000
    ..These findings extend research on nicotine abstinence effects and on the dissipation of tolerance to nicotine deprivation intervals of nearly 2 weeks and confirm prior observations of variability across different response systems...
  11. ncbi request reprint Prolonged nicotine patch use in quitters with past abstinence-induced depressed mood
    Ovide F Pomerleau
    Nicotine Research Laboratory, Behavioral Medicine Program, Department of Psychiatry, University of Michigan Medical School, 475 Market Place, Suite L, Box 5, Ann Arbor, MI 48108, USA
    J Subst Abuse Treat 24:13-8. 2003
    ....
  12. pmc Web-based smoking-cessation programs: results of a randomized trial
    Victor J Strecher
    Center for Health Communications Research, University of Michigan School of Public Health, Ann Arbor, MI 48109 0471, USA
    Am J Prev Med 34:373-81. 2008
    ..This study aimed to (1) identify active psychosocial and communication components of a web-based smoking-cessation intervention and (2) examine the impact of increasing the tailoring depth on smoking cessation...
  13. pmc Race differences in factors relating to smoking initiation
    Raphaela Finkenauer
    Nicotine Research Laboratory, University of Michigan Department of Psychiatry, USA
    Addict Behav 34:1056-9. 2009
    ..2+/-0.2 vs. 3.4+/-0.5; p<.10) as reasons for starting to smoke. Further research is needed to determine the relative contributions of genetic, developmental, and socio-cultural factors to these findings...
  14. ncbi request reprint Differences in smoking-related variables based on phenylthiocarbamide "taster" status
    Sandy M Snedecor
    Nicotine Research Laboratory, University of Michigan Department of Psychiatry, Ann Arbor, MI 48105, USA
    Addict Behav 31:2309-12. 2006
    ..1 [2.9] vs. 6.8 [3.1], p<.05). Results suggest that among smokers, ability to taste PTC may confer some protection from development of nicotine dependence and positive reinforcement from smoking...
  15. ncbi request reprint Unaided smoking cessation among smokers in treatment for alcohol dependence
    Maher Karam-Hage
    Nicotine Research Program, Univ of Michigan Department of Psychiatry, Ann Arbor, MI, USA
    Addict Behav 30:1247-53. 2005
    ..These findings suggest that quitting smoking may be associated with low levels of nicotine dependence and favorable alcohol treatment response in alcoholic smokers...
  16. ncbi request reprint Behavioral medicine: the challenge of integrating psychological and behavioral approaches into primary care
    Peter C Trask
    Behavioral Medicine Program, University of Michigan, Ann Arbor 48108 0757, USA
    Eff Clin Pract 5:75-83. 2002
  17. ncbi request reprint Differences in accuracy of offspring assessment based on parental smoking status
    Cynthia S Pomerleau
    Nicotine Research Laboratory, Department of Psychiatry, University of Michigan, 475 Market Place, Ste L, Ann Arbor, MI 48108, USA
    Addict Behav 30:437-41. 2005
    ..Overall, these results support the utility of proxy reports of parental smoking phenotype by adult informants when self-report is unavailable...
  18. ncbi request reprint Agreement between proband and parental self-report of smoking behavior and nicotine dependence
    Judith L Marks
    Nicotine Research Laboratory, University of Michigan, Ann Arbor, MI 48108, USA
    Nicotine Tob Res 5:527-33. 2003
    ..Our findings should aid investigators in defining the limits of proband reports of parental smoking behavior and identify opportunities for the development of better approaches for the assessment of familial nicotine dependence...
  19. ncbi request reprint Defining a never-smoker: results from the nonsmokers survey
    Cynthia S Pomerleau
    Nicotine Research Laboratory, Behavioral Medicine Program, Department of Psychiatry, University of Michigan, 475 Market Place, Suite L, Box 5, Ann Arbor 48108, USA
    Addict Behav 29:1149-54. 2004
    ..ever-smokers may help refine this cutpoint and shed light on what protects some people who experiment with smoking from becoming chronic users...
  20. ncbi request reprint Relationship between early experiences with tobacco and early experiences with alcohol
    Cynthia S Pomerleau
    Department of Psychiatry, Nicotine Research Laboratory, Behavioral Medicine Program, University of Michigan, 475 Market Place, Suite L, Box 5, Ann Arbor 48108, USA
    Addict Behav 29:1245-51. 2004
    ..These preliminary findings may have implications for understanding the mechanisms underlying the smoking-alcohol link...
  21. ncbi request reprint Smoking patterns and abstinence effects in smokers with no ADHD, childhood ADHD, and adult ADHD symptomatology
    Cynthia S Pomerleau
    Nicotine Research Laboratory, Behavioral Medicine Program, Department of Psychiatry, University of Michigan, 475 Market Place, Suite L, Ann Arbor, MI 48108, USA
    Addict Behav 28:1149-57. 2003
    ..Thus, studying people with childhood symptoms of ADHD, even in the absence of an adult diagnosis, may shed light on the known association between smoking and ADHD...
  22. ncbi request reprint Heterogeneity in phenotypes based on smoking status in the Great Lakes Smoker Sibling Registry
    Cynthia S Pomerleau
    Nicotine Research Laboratory, Behavioral Medicine Program, Department of Psychiatry, University of Michigan, 475 Market Place, Suite L, Ann Arbor, MI 48108, USA
    Addict Behav 29:1851-5. 2004
    ....
  23. pmc Never-smokers with a positive family smoking history are more likely to be overweight or obese than never-smokers with a negative family smoking history
    Cynthia S Pomerleau
    University of Michigan, Department of Psychiatry, USA
    Eat Behav 10:49-51. 2009
    ..Further research in larger samples, using more complex statistical models, will be needed to disentangle these issues and identify causal pathways...
  24. pmc Novel genes identified in a high-density genome wide association study for nicotine dependence
    Laura Jean Bierut
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid, Box 8134, St Louis, MO 63110, USA
    Hum Mol Genet 16:24-35. 2007
    ..This work anticipates the future directions of large-scale genome wide association studies with state-of-the-art methodological approaches and sharing of data with the scientific community...
  25. pmc Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking
    Richard Sherva
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Addiction 103:1544-52. 2008
    ..To extend the previously identified association between a single nucleotide polymorphism (SNP) in neuronal acetylcholine receptor subunit alpha-5 (CHRNA5) and nicotine dependence to current smoking and initial smoking-experience phenotypes...
  26. pmc Variants in nicotinic receptors and risk for nicotine dependence
    Laura Jean Bierut
    Department of Psychiatry, Washington University School of Medicine, Box 8134, 660 South Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 165:1163-71. 2008
    ....
  27. pmc The role of engagement in a tailored web-based smoking cessation program: randomized controlled trial
    Victor J Strecher
    Center for Health Communications Research, University of Michigan School of Public Health, Ann Arbor, MI 48109 0471, USA
    J Med Internet Res 10:e36. 2008
    ..First, does engagement with program content predict long-term outcomes? Second, which users are most likely to drop out or disengage from the program? Third, do particular intervention strategies enhance engagement?..
  28. pmc Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
    Scott F Saccone
    Department of Psychiatry, Box 8134, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Hum Mol Genet 16:36-49. 2007
    ..Other genes among the top signals were KCNJ6 and GABRA4. This study represents one of the most powerful and extensive studies of nicotine dependence to date and has found novel risk loci that require confirmation by replication studies...
  29. ncbi request reprint Nicotine metabolite ratio as a predictor of cigarette consumption
    Neal L Benowitz
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 1220, USA
    Nicotine Tob Res 5:621-4. 2003
    ..This finding supports the hypothesis that the rate of nicotine metabolism is a determinant of the level of cigarette consumption and supports the use of the 3-HC:cotinine ratio as a noninvasive marker of nicotine metabolism...

Research Grants24

  1. DIFFERENTIATION OF PHENOTYPES FOR SMOKING
    Ovide Pomerleau; Fiscal Year: 2003
    ..abstract_text> ..
  2. Effects of family smoking history in never-smokers
    Ovide Pomerleau; Fiscal Year: 2006
    ....
  3. CORTICOSTEROIDS, STRESS, AND NICOTINE DEPENDENCE
    Ovide Pomerleau; Fiscal Year: 1992
    ..Overall, the project seeks to identify mechanisms whose elucidation may increase the understanding of smoking and nicotine dependence and lead to the development of new tools for treating smoking...
  4. DIFFERENTIATION OF PHENOTYPES FOR SMOKING
    Ovide Pomerleau; Fiscal Year: 1999
    ....
  5. Candidate Genes for Smoking In Related and Unrelated Individuals
    Ovide Pomerleau; Fiscal Year: 2007
    ..abstract not provided ..