ANDREW EMIL POLLARD

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Optical mapping of V(m) and Ca(i)(2+) in a model of arrhythmias induced by local catecholamine application in patterned cell cultures
    David Z Lan
    Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA
    Pflugers Arch 453:871-7. 2007
  2. doi request reprint Linear electrode arrays for stimulation and recording within cardiac tissue space constants
    Andrew E Pollard
    Department of Biomedical Engineering, Cardiac Rhythm Management Laboratory, University of Alabama, Birmingham, AL 35294, USA
    IEEE Trans Biomed Eng 55:1408-14. 2008
  3. ncbi request reprint Functional reentry's influence on intracellular calcium in the LRd membrane equations
    A E Pollard
    Department of Biomedical Engineering and the Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham 35294, USA
    IEEE Trans Biomed Eng 47:1228-36. 2000
  4. ncbi request reprint Multisite interstitial stimulation for cardiac micro-impedance measurements
    Andrew E Pollard
    Biomedical Engineering and Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Conf Proc IEEE Eng Med Biol Soc 1:1572-5. 2006
  5. ncbi request reprint Cardiac microimpedance measurement in two-dimensional models using multisite interstitial stimulation
    Andrew E Pollard
    Cardiac Rhythm Management Laboratory, Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Physiol Heart Circ Physiol 290:H1976-87. 2006
  6. ncbi request reprint Feasibility of cardiac microimpedance measurement using multisite interstitial stimulation
    Andrew E Pollard
    Cardiac Rhythm Management Laboratory, Univ of Alabama at Birmingham, Volker Hall B140, 1670 University Blvd, Birmingham, AL 35294, USA
    Am J Physiol Heart Circ Physiol 287:H2402-11. 2004
  7. ncbi request reprint From myocardial cell models to action potential propagation
    Andrew E Pollard
    Department of Biomedical Engineering, Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham, AL 35294 9440, USA
    J Electrocardiol 36:43-9. 2003
  8. ncbi request reprint Modulation of triggered activity by uncoupling in the ischemic border. A model study with phase 1b-like conditions
    Andrew E Pollard
    Department of Biomedical Engineering, Cardiac Rhythm Management Laboratory, University of Alabama at Bermingham, Volker Hall B140 1670 University Blvd, Birmingham, AL 35294, USA
    Cardiovasc Res 56:381-92. 2002
  9. ncbi request reprint Measuring surface potential components necessary for transmembrane current computation using microfabricated arrays
    J James Wiley
    Cardiac Rhythm Management Laboratory, Univ of Alabama at Birmingham, Volker Hall B140, 1670 Univ Blvd, Birmingham, AL 35294, USA
    Am J Physiol Heart Circ Physiol 289:H2468-77. 2005
  10. ncbi request reprint Spontaneous activity induced in rabbit Purkinje myocytes during coupling to a depolarized model cell
    Delilah J Huelsing
    Cardiac Rhythm Management Lab, Department of Biomedical Engineering, University of Alabama Birmingham, Volker Hall B140, 1670 University Blvd, Birmingham, AL 35294, USA
    Cardiovasc Res 59:620-7. 2003

Research Grants

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Optical mapping of V(m) and Ca(i)(2+) in a model of arrhythmias induced by local catecholamine application in patterned cell cultures
    David Z Lan
    Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA
    Pflugers Arch 453:871-7. 2007
    ..The location of the arrhythmia source correlated with localized Ca(i)(2+) oscillations suggesting that arrhythmias were caused by Ca(i)(2+) overload at these locations...
  2. doi request reprint Linear electrode arrays for stimulation and recording within cardiac tissue space constants
    Andrew E Pollard
    Department of Biomedical Engineering, Cardiac Rhythm Management Laboratory, University of Alabama, Birmingham, AL 35294, USA
    IEEE Trans Biomed Eng 55:1408-14. 2008
    ..These findings are significant because they suggest intracellular and interstitial microimpedance mesurements in heart experiments will be straightforward...
  3. ncbi request reprint Functional reentry's influence on intracellular calcium in the LRd membrane equations
    A E Pollard
    Department of Biomedical Engineering and the Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham 35294, USA
    IEEE Trans Biomed Eng 47:1228-36. 2000
    ..However, [Ca2+]i instabilities did not always fractionate depolarization wavefronts during reentry. Fractionation depended, in part, upon CICR and SCR parameters in the LRd formulation for SR Ca2+ release...
  4. ncbi request reprint Multisite interstitial stimulation for cardiac micro-impedance measurements
    Andrew E Pollard
    Biomedical Engineering and Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Conf Proc IEEE Eng Med Biol Soc 1:1572-5. 2006
    ..Our findings suggest development of microfabricated devices to implement the multisite stimulation procedure would facilitate routine measurement as a component of cardiac electrophysiologic study...
  5. ncbi request reprint Cardiac microimpedance measurement in two-dimensional models using multisite interstitial stimulation
    Andrew E Pollard
    Cardiac Rhythm Management Laboratory, Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Physiol Heart Circ Physiol 290:H1976-87. 2006
    ..Our findings suggest that development of microfabricated devices to implement the procedure would facilitate routine measurement as a component of cardiac electrophysiological study...
  6. ncbi request reprint Feasibility of cardiac microimpedance measurement using multisite interstitial stimulation
    Andrew E Pollard
    Cardiac Rhythm Management Laboratory, Univ of Alabama at Birmingham, Volker Hall B140, 1670 University Blvd, Birmingham, AL 35294, USA
    Am J Physiol Heart Circ Physiol 287:H2402-11. 2004
    ..Our findings suggest development of microfabricated devices to implement the procedure would facilitate routine measurement as a component of cardiac electrophysiological study...
  7. ncbi request reprint From myocardial cell models to action potential propagation
    Andrew E Pollard
    Department of Biomedical Engineering, Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham, AL 35294 9440, USA
    J Electrocardiol 36:43-9. 2003
    ..Additionally, the integrating of membrane equations into models where coupling to represent current flow paths associated with the anisotropic tissue structure is described...
  8. ncbi request reprint Modulation of triggered activity by uncoupling in the ischemic border. A model study with phase 1b-like conditions
    Andrew E Pollard
    Department of Biomedical Engineering, Cardiac Rhythm Management Laboratory, University of Alabama at Bermingham, Volker Hall B140 1670 University Blvd, Birmingham, AL 35294, USA
    Cardiovasc Res 56:381-92. 2002
    ..Triggered beats during regional ischemia may depend upon the electrical source and sink charge interactions between adjacent regions of normal and ischemic cardiac tissue that are partly controlled by electrical coupling...
  9. ncbi request reprint Measuring surface potential components necessary for transmembrane current computation using microfabricated arrays
    J James Wiley
    Cardiac Rhythm Management Laboratory, Univ of Alabama at Birmingham, Volker Hall B140, 1670 Univ Blvd, Birmingham, AL 35294, USA
    Am J Physiol Heart Circ Physiol 289:H2468-77. 2005
    ....
  10. ncbi request reprint Spontaneous activity induced in rabbit Purkinje myocytes during coupling to a depolarized model cell
    Delilah J Huelsing
    Cardiac Rhythm Management Lab, Department of Biomedical Engineering, University of Alabama Birmingham, Volker Hall B140, 1670 University Blvd, Birmingham, AL 35294, USA
    Cardiovasc Res 59:620-7. 2003
    ..The purpose of the present study was to determine the effects of injury current across the Purkinje-ventricular interface in the development of abnormal automaticity...
  11. ncbi request reprint Shock-induced changes of Ca(i)2+ and Vm in myocyte cultures and computer model: Dependence on the timing of shock application
    Vidya Raman
    Department of Biomedical Engineering, University of Alabama at Birmingham, 1670 University Blvd, VH B126, Birmingham, Alabama 35294, USA
    Cardiovasc Res 73:101-10. 2007
    ..The effects of shocks on Ca(i)2+ and Vm were investigated in geometrically defined cell cultures and in a computer model...
  12. ncbi request reprint Comparison of conventional and biventricular antitachycardia pacing in a geometrically realistic model of the rabbit ventricle
    Israel A Byrd
    Department of Biomedical Engineering, Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Cardiovasc Electrophysiol 15:1066-77. 2004
    ..We hypothesized that using the additional lead for ATP would improve therapy by advancing the orthodromic wavefront, thereby reducing the size of the excitable gap and inducing block of all reentrant activity...
  13. ncbi request reprint Interactions between paced wavefronts and monomorphic ventricular tachycardia: implications for antitachycardia pacing
    Israel A Byrd
    Cardiac Rhythm Management Laboratory, Department of Biomedical Engineering, University of Alabama at Birmingham, Alabama 35294, USA
    J Cardiovasc Electrophysiol 17:1129-39. 2006
    ..We used optical mapping to assess those interactions during single and dual site pacing of rabbit ventricular epicardium...
  14. ncbi request reprint Delayed termination following pacing induced shifts from monomorphic to polymorphic ventricular tachycardia: implications for antitachycardia pacing
    Israel A Byrd
    Dept of Biomed Eng, Alabama Univ, Birmingham, AL 35294, USA
    Conf Proc IEEE Eng Med Biol Soc 1:3939-42. 2006
    ....
  15. pmc Stimulatory current at the edge of an inactive conductor in an electric field: role of nonlinear interfacial current-voltage relationship
    Jared A Sims
    Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    IEEE Trans Biomed Eng 57:442-9. 2010
    ..Interfacial nonlinearity concentrates current near the edge where it can excite the heart. Stimulatory current at edges may account for the reported decrease in defibrillation threshold by inactive conductors...
  16. pmc A biophysical model for cardiac microimpedance measurements
    Andrew E Pollard
    Cardiac Rhythm Management Laboratory, Univ of Alabama at Birmingham, Volker Hall B140, 1670 Univ Blvd, Birmingham, AL 35294
    Am J Physiol Heart Circ Physiol 298:H1699-709. 2010
    ..Because of the small electrode size, separation of interstitial from intracellular compartment contributions is readily achieved...
  17. ncbi request reprint Use of translucent indium tin oxide to measure stimulatory effects of a passive conductor during field stimulation of rabbit hearts
    Stephen B Knisley
    University of North Carolina at Chapel Hill, Department of Biomedical Engineering, CB 7575, 152 MacNider Hall, Chapel Hill, NC 27599 7575, USA
    Am J Physiol Heart Circ Physiol 289:H1137-46. 2005
    ..Thus ITO allows study of the stimulatory effects of a passive conductor in an electric field...
  18. ncbi request reprint Effects of electrical shocks on Cai2+ and Vm in myocyte cultures
    Vladimir G Fast
    Department of Biomedical Engineering, University of Alabama at Birmingham, 1670 University Blvd, VH B149, Birmingham, AL 35294, USA
    Circ Res 94:1589-97. 2004
    ..Outward flow of I(CaL) plays an important role in Ca(i)2+ decrease in the DeltaV+m areas. Very strong shocks caused smaller negative DeltaCa(i)2+ and postshock elevation of diastolic Ca(i)2+, likely caused by membrane electroporation...
  19. ncbi request reprint Contributions of Purkinje-myocardial coupling to suppression and facilitation of early afterdepolarization-induced triggered activity
    Ingrid Schafferhofer-Steltzer
    Institut fur Biophysik, Medizinische Universitat Graz, A 8010 Karl Franzens Universitaet, Graz, Austria
    IEEE Trans Biomed Eng 52:1522-31. 2005
    ....
  20. ncbi request reprint Cell-to-cell electrical interactions during early and late repolarization
    Kenneth W Spitzer
    Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, USA
    J Cardiovasc Electrophysiol 17:S8-S14. 2006
    ..This high sensitivity of the plateau to variations in junctional interactions arises from the large increase in membrane resistance that occurs during this phase of the action potential...
  21. ncbi request reprint Bayesian analysis of fiber impedance measurements
    Roger C Barr
    Biomedical Engineering, Duke University, Durham, NC 27708 USA
    Conf Proc IEEE Eng Med Biol Soc 2007:423-9. 2007
    ..The results show that the micro impedances were found satisfactorily using realistic parameters and noise levels. The overall quantitative evaluation is promising for future experimental measurements...
  22. doi request reprint Progress in modeling cardiac electrical activity: a long way from spherical cows
    Raymond E Ideker
    Heart Rhythm 5:1045-6. 2008

Research Grants3

  1. Novel Methods for Cardiac Micro-Impedance Measurement
    Andrew Pollard; Fiscal Year: 2005
    ..abstract_text> ..
  2. Novel Methods for Cardiac Micro-Impedance Measurement
    Andrew Pollard; Fiscal Year: 2009
    ....
  3. Novel Methods for Cardiac Micro-Impedance Measurement
    ANDREW EMIL POLLARD; Fiscal Year: 2010
    ....