Research Topics
Species | Hiram C PolkSummaryAffiliation: University of Louisville Country: USA Publications
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Publications
Married to the boss, or how checking the box changed my lifeSusan Galandiuk
Department of Surgery, University of Louisville, Louisville, KY 40292, USA
Am J Surg 190:300-4. 2005- Commentary on the professional career of John S. Spratt, Jr., MD, MPHHiram C Polk
Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
J Surg Oncol 88:112. 2004 
A proposal for enhancing the general surgical workforce and access to surgical careHiram C Polk
Department of Surgery, University of Louisville, Louisville, KY 40292, USA
Ann Surg 255:611-7. 2012..We also sought to define workable solutions within the existing framework of medical accreditation and certification...- Renewal of surgical quality and safety initiatives: a multispecialty challengeHiram C Polk
Department of Surgery and Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, KY 40292, USA
Mayo Clin Proc 81:345-52. 2006..This effort has defined factors worthy of further verification and provides a framework for an ethical and valid pay-for-performance scheme... - Comments by Dr. Polk upon occasion of the mid-winter President's dinner of the American Surgical Association, community celebration of his chairmanship at the University of Louisville, and at the reunion of former residents and studentsHiram C Polk
Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, USA
Am J Surg 190:158-60. 2005 - The complementary value of trained abstractors and surgeons in the more accurate assessment of surgical qualityHiram C Polk
Department of Surgery, University of Louisville, Louisville, KY 40292, USA
Am J Med Qual 25:444-8. 2010..If "quality" is to be validly reported and used for assessment, punishment, or reward processes, then the value of these 2 sources is too great to ignore... - A situational overview of surgical quality and safety in 2010Hiram C Polk
Department of Surgery, University of Louisville, Louisville, KY 40292, USA
Am J Surg 200:82-9. 2010..Surgical safety and quality initiatives have now moved to the front of the agenda for contemporary surgery... - Attitudes of surgical specialists toward venous thromboembolism prophylaxis in surgical patientsHiram C Polk
Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
Am Surg 74:189-94. 2008..Actual practices used in the Surgical Care Improvement Project 2004 varied even more widely and were at substantial variance from recommendations and current Centers for Medicare and Medicaid Services quality measures... - Commentary on the role of government in health care: a societal issueHiram C Polk
Department of Surgery, University of Louisville, 550 S Jackson Street, Louisville, KY 40292, USA
Am J Surg 191:161. 2006 
Quality and safety in surgical careHiram C Polk
Department of Surgery, University of Louisville, Louisville, KY 40292, USA
Ann Surg 243:439-48. 2006- Glucose and surgical sepsis: a study of underlying immunologic mechanismsMotaz Qadan
The Price Institute of Surgical Research, University of Louisville School of Medicine, 511 S Floyd Street, Louisville, KY 40202, USA
J Am Coll Surg 210:966-74. 2010..We sought to investigate the effects of varying glucose concentrations on previously tested, prognostically significant, innate immune parameters, to define any potential effects of glucose at the cellular level... - In vitro study of variables relevant to perioperative care of the surgical patient: glucose, osmolarity, and rewarmingAshley Dickinson
Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, KY
J Am Coll Surg 212:180-6. 2011..We sought to determine the effects of altering osmolarity and the reversibility of the detrimental immunologic effects of hypothermia on human monocyte HLA-DR surface expression and reactive oxygen species (ROS) formation... - Optimizing surgical care: a contemporary assessment of temperature, oxygen, and glucoseAshley Dickinson
Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
Am Surg 76:571-7. 2010..These factors and their associated effects are discussed through the examination of recent clinical and scientific studies to provide an up-to-date evidence-based review... - Differences and similarities between rural and urban operationsSusan Galandiuk
Department of Surgery, Price Institute for Surgical Research, University of Louisville School of Medicine, Louisville, KY, USA
Surgery 140:589-96. 2006..The importance of rural operations is magnified by super-specialization, uneven geographic distribution, and special educational needs. Definition of practice patterns and quality measures are needed... - Oxygen and surgical site infection: a study of underlying immunologic mechanismsMotaz Qadan
The Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, Kentucky, USA
Anesthesiology 113:369-77. 2010..The authors sought to investigate the effects of hyperoxia on previously tested and prognostically significant innate immune parameters to uncover the potential effects of hyperoxia at the cellular level... - Venous thromboembolism in elective operations: balancing the choicesMotaz Qadan
Price Institute of Surgical Research, Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, USA
Surgery 144:654-60, discussion 660-1. 2008..We report the incidence of VTE from 3 sources to provide an estimate of the true risk of the complication in elective surgery... - Mortality after elective colon resection: the search for outcomes that define quality in surgical practiceAdrian T Billeter
Price Institute of Surgical Research, Department of Surgery, School of Medicine, University of Louisville, Louisville, KY 40292, USA
J Am Coll Surg 214:436-43; discussion 443-4. 2012..Wide ranges of reported hospital death rates led us to hypothesize that survival after elective colon resection would be a legitimate outcomes measure for quality of surgical practice... - Diabetes and hyperglycemia: strict glycemic controlMatthias Turina
Department of Surgery, Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, KY, USA
Crit Care Med 34:S291-300. 2006.... - Expanded surgical time out: a key to real-time data collection and quality improvementTerry Altpeter
University of Louisville Hospital, Department of Surgery, University of Louisville School of Medicine and Quality, Louisville, KY 40292, USA
J Am Coll Surg 204:527-32. 2007..See: Transforming the Surgical "Time-Out" Into a Comprehensive "Preparatory Pause." Backster A, Teo A, Swift M, MD, Polk HC Jr, MD, FACS, Harken AH, MD, FACS. J Cardiac Surg, in press.).. - A Hamblin Letton Lecture. The continuing need to attract surgery students to surgical specialty careers: a step forward but at what expense?Hiram C Polk
Department of Surgery, University of Louisville School of Medicine, Center for Advanced Surgical Technologies, Louisville, Kentucky 40292, USA
Am Surg 70:379-83. 2004 - Effects of hyperglycemia, hyperinsulinemia, and hyperosmolarity on neutrophil apoptosisMatthias Turina
Department of Surgery, Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
Surg Infect (Larchmt) 7:111-21. 2006.... - Patient safety and quality in surgeryMichael H McCafferty
Department of Surgery, Section of Colorectal Surgery, University of Louisville, 550 South Jackson Street, Louisville, Kentucky 40202, USA
Surg Clin North Am 87:867-81, vii. 2007..In our current climate, this emphasis on quality and safety will remain a high priority. Surgeon leadership at all levels is key to our professional viability... - Is there a role for bowel preparation and oral or parenteral antibiotics in infection control in contemporary colon surgery?Susan Galandiuk
Section of Colon and Rectal Surgery, Department of Surgery, University of Louisville, Louisville, KY 40292, USA
Adv Surg 45:131-40. 2011.... - Mannitol upregulates monocyte HLA-DR, monocyte and neutrophil CD11b, and inhibits neutrophil apoptosisMatthias Turina
Department of Surgery, Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, KY 40292, USA
Inflammation 31:74-83. 2008..Further systematic evaluation is indicated to define the precise immunomodulating actions of mannitol, and to assess these effects in patients receiving such therapy... - Opportunities for improved performance in surgical specialty practiceSuhal S Mahid
Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
Ann Surg 247:380-8. 2008..To identify opportunities for improvement in quality performance profile while maintaining better clinical outcomes... - Process and outcome measures in specialty surgery: early steps in defining qualityHiram C Polk
Department of Surgery, University of Louisville, KY, USA
Bull Am Coll Surg 90:8-15. 2005..It has been said that perfection is an enemy of quality; the first step toward best practices is to implement, refine, and improve better practices... - A brief private group practice rotation changes junior medical students' perception of the surgical lifestyleMary B Carter
Office of Curriculum Development and Evaluation, University of Louisville, School of Medicine, Instructional B Building, Room 308, Louisville, KY, 40292, USA
Am J Surg 189:458-61. 2005..We hypothesized that a 4-day preceptorship with surgeons in private practice would improve student perception of surgery as a valid career choice without compromising student educational performance... - Practicing surgeons lead in quality care, safety, and cost controlEugene H Shively
Department of Surgery, University of Louisville School of Medicine; and Quality Surgical Solutions, PLLC, Louisville, KY, USA
Ann Surg 239:752-60; discussion 760-2. 2004..We have discovered wide areas for improvements in surgery by adherence to simple protocols, minimizing death and complications and clarifying cost issues... - Transforming the surgical "time-out" into a comprehensive "preparatory pause"Anika Backster
Department of Surgery, University of California, San Francisco East Bay, Oakland, California, USA
J Card Surg 22:410-6. 2007..We propose expansion of the "time-out" to include five well-documented perioperative risk avoidance strategies that many of us overlook all too often... - Does clinically relevant temperature change miRNA and cytokine expression in whole blood?Adrian T Billeter
Hiram C Polk Jr MD Department of Surgery, Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, KY 40292, USA
J Interferon Cytokine Res 32:485-94. 2012..In conclusion, TNF-α, IL-6, and IL-10 production is highly variable among different persons, but temperature affects the expression of miRNAs, which may consequently alter the production of TNF-α... - Short-term hyperglycemia in surgical patients and a study of related cellular mechanismsMatthias Turina
Department of Surgery, Price Institute of Surgical Research, University of Louisville School of Medicine, 550 South Jackson Street, Louisville, KY 40294, USA
Ann Surg 243:845-51; discussion 851-3. 2006..This may provide a mechanism by which high glucose and insulin impair innate immunity. It also appears that perioperative maintenance of normoglycemia will become a valid performance measure for practicing surgical specialists... - Mutual reporting of process and outcomes enhances quality outcomes for colon and rectal resectionsSusan Galandiuk
Department of Surgery, University of Louisville, KY 40292, USA
Surgery 136:833-41. 2004.... - Program directors in surgery agree that residents should be formally trained in business and practice managementVincent C Lusco
Department of Surgery, and the Institute for Bioethics Health Policy and Law, University of Louisville School of Medicine, Louisville, KY 40292, USA
Am J Surg 189:11-3. 2005..CONCLUSIONS: Development of simple curricula aimed at preparing surgical residents for business and practice management could promote the contemporary education of surgeons... - Monocyte HLA-DR and interferon-gamma treatment in severely injured patients--a critical reappraisal more than a decade laterMatthias Turina
Price Institute of Surgical Research and the Trauma Program in Surgery, Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, USA
J Am Coll Surg 203:73-81. 2006 - Impact of diabetes mellitus and metabolic disordersMatthias Turina
Department of Surgery, Price Institute of Surgical Research, 511 South Floyd Street, MDR Building, Room 312, Louisville, KY 40202, USA
Surg Clin North Am 85:1153-61, ix. 2005.... - Further results of incorporating innovative procedures in a surgical residencyFarid J Kehdy
Department of Surgery, University of Louisville, and the Center for Advanced Surgical Technologies, Louisville, KY 40292, USA
Surg Innov 12:167-71. 2005.... - Addition of "near-miss" cases enhances a quality improvement conferenceMichael H McCafferty
Department of Surgery, University of Louisville School of Medicine, and the Trauma Program in Surgery, University of Louisville Hospital, Louisville, KY, USA
Arch Surg 139:216-7. 2004..quot;Near-miss" is a useful focus for such a conference, in that it avoids a focus on ultimate personal guilt and minimizes exposure to litigation (ie, a nonevent)... - Roger T. Sherman Lecture. Surgical quality and safety: the patient comes firstHiram C Polk
Department of Surgery, University of Louisville School of Medicine, The Price Institute of Surgical Research, Louisville, Kentucky 40292, USA
Am Surg 73:538-42. 2007 - Another duel in the sun: weighing the balances between sun protection, tanning beds, and malignant melanomaDaniel J Roberts
School of Public Health and Information Sciences, University of Louisville, Kentucky
Clin Pediatr (Phila) 48:614-22. 2009..The purpose of this report is to put the dueling factors of risk and prevention for melanoma in perspective for the thoughtful pediatric specialist to facilitate preteen preventive health counseling... - Sequential improvements in organ procurement increase the organ donation rateAdrian T Billeter
Department of Surgery, Price Institute of Surgical Research, School of Medicine, University of Louisville, 511 South Floyd Street, Louisville, KY 40202, United States
Injury 43:1805-10. 2012..The purpose of this article is to propose how sequentially introduced measures can increase organ donation rates as well as improve organ procurement... - Hiram C. Polk: the horsemanJ David Richardson
Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, USA
Am J Surg 190:285-8. 2005 - Perioperative supplemental oxygen therapy and surgical site infection: a meta-analysis of randomized controlled trialsMotaz Qadan
Department of Surgery, Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
Arch Surg 144:359-66; discussion 366-7. 2009..To conduct a meta-analysis of randomized controlled trials in which high inspired oxygen concentrations were compared with standard concentrations to assess the effect on the development of surgical site infections (SSIs)... - Broad-based general surgery training is a model of continued utility for the futureWilliam G Cheadle
Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, USA
Ann Surg 239:627-32; discussion 632-6. 2004..Our faculty includes surgeons with both broad-based and narrowly focused practices. In light of duty-hour restrictions and proposed changes in surgical training, we assessed the results of this model over an extended period... - Hypothermia and surgery: immunologic mechanisms for current practiceMotaz Qadan
Price Institute of Surgical Research, University of Louisville School of Medicine, Medical Dental Research Building 3rd Floor, 511 South Floyd St, Louisville, Kentucky 40202, USA
Ann Surg 250:134-40. 2009..To examine cellular and immunologic mechanisms by which intraoperative hypothermia affects surgical patients... - Quality, safety, and transparencyHiram C Polk
Department of Surgery, University of Louisville, KY 40292, USA
Ann Surg 242:293-301. 2005 - Acute hyperglycemia and the innate immune system: clinical, cellular, and molecular aspectsMatthias Turina
Department of Surgery, The Price Institute of Surgical Research, University of Louisville School of Medicine, University of Louisville Hospital, Louisville, KY, USA
Crit Care Med 33:1624-33. 2005.... - Hiram Polk and the American Journal of SurgeryKirby I Bland
Department of Surgery, University of Alabama at Birmingham, 1530 3rd Avenue South, 502 BDB, Birmingham, AL 35294, USA
Am J Surg 190:338-43. 2005 - MicroRNA as a new factor in lung and esophageal cancerAdrian T Billeter
Department of Surgery, Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
Semin Thorac Cardiovasc Surg 24:155-65. 2012..Cancer cells actively secrete miRNAs, and these miRNA profiles can be found in blood. We outline, here, how these miRNAs may aid in diagnosis and treatment of lung and esophageal cancers, as well as their apparent limitations... - Surgeon-led initiatives cut costs and enhance the quality of endoscopic and laparoscopic proceduresJeff W Allen
Department of Surgery, University of Louisville School of Medicine, Center for Advanced Surgical Technologies of Norton Hospital, Louisville, Kentucky 40292, USA
JSLS 7:243-7. 2003..One participating teaching hospital used its own financial data and predicted that if all surgeons at their facility followed the protocols and had similar results, a savings of dollar 1.1 million per quarter would be obtained... - Racial trends in mammography rates: a population-based studyAnees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, KY, USA
Surgery 144:467-72. 2008..The rates of mammography have been declining over the last 5 years. The objective of this study was to examine racial disparities in this trend... - Rapidly expanding demands on hospital quality personnel threaten the quality of their reportsHiram C Polk
Department of Surgery and the Price Institute of Surgical Research, and Quality Surgical Solutions, PLLC, University of Louisville, Louisville, KY 40292, USA
J Am Coll Surg 207:604-6. 2008 - Clinical and economic outcomes of oral linezolid versus intravenous vancomycin in the treatment of MRSA-complicated, lower-extremity skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureusJ Neal Sharpe
SharpCare, LLC, 9505 Williamsburg Plaza, Suite 201, Louisville, KY 40222, USA
Am J Surg 189:425-8. 2005..This open-label study compared oral linezolid and intravenous vancomycin for management of complicated skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA)... - Methamphetamine laboratory explosions: a new and emerging burn injuryAriel P Santos
Department of Surgery, Epidemiology and Statistics Training (CREST) Program, University of Louisville, Louisville, Kentucky 40292, USA
J Burn Care Rehabil 26:228-32. 2005..It also is associated with lack of insurance coverage and poor follow-up after injury. This injury has a significant impact not only on patients but also on the healthcare system... - Profitable versus unprofitable expansion of trauma and critical care surgeryJorge L Rodriguez
Department of Surgery, University of Louisville University of Louisville and the Trauma Program in Surgery, University of Louisville Hospital, Louisville, Kentucky 40292, USA
Ann Surg 242:603-6; discussion 606-9. 2005..We assessed whether this change will have an impact on the financial challenges that this specialty confronts, including inadequate reimbursement for efforts exerted... - Endotoxin inhibits apoptosis but induces primary necrosis in neutrophilsMatthias Turina
Department of Surgery, The Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
Inflammation 29:55-63. 2005..6% in controls to 30.6%, p < 0.001). This increase in direct neutrophil necrosis following LPS activation may amplify local proinflammatory effects through less well controlled release of neutrophil contents into surrounding tissue... - The evolution of guidelines toward standards of practiceHiram C Polk
Department of Surgery, University of Louisville School of Medicine, Price Institute of Surgical Research and Quality Surgical Solutions, Louisville, Kentucky 40292, USA
Am Surg 72:1017-20; discussion 1021-30, 1133-48. 2006..A careful and ongoing analysis of the self-serving aspects of such work is essential. However, these observations and our work make the decision for elective surgical operations safer than it has ever been... - A closer look at surgical quality measures across different surgical specialtiesJames M Watkins
Taylor Regional Hospital, Campbellsville, KY, USA
Am J Surg 200:90-6. 2010..Most studies of surgical quality improvement have been performed in large and/or teaching hospitals; the efficacy of safety and quality efforts in smaller hospitals have not been reported... - Does additional surgical training increase participation in randomized controlled trials?Robert C G Martin
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
Am J Surg 185:239-43. 2003..The prospective randomized controlled trial (PRCT) is agreeably the gold standard in reporting data on patient management. This study evaluates the impact of specialty training on the leadership, development, and enrollment in PRCT... - Clinical characteristics of familial adenomatous polyposis and management of duodenal adenomasEmilio Morpurgo
Department of Surgery, University of Louisville School of Medicine and the Digestive Health Center, Louisville, Kentucky 40292, USA
J Gastrointest Surg 8:559-64. 2004.... - The challenge of small numbers to the contemporary excellence of elective specialty surgeryHiram C Polk
Department of Surgery, University of Louisville School of Medicine and Price Institute of Surgical Research and Quality Surgical Solutions, Louisville, Kentucky 40292, USA
Am Surg 72:1043-5; discussion 1061-9, 1133-48. 2006 - Symposium introductionHiram C Polk
Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, USA
Am J Surg 184:185-6. 2002 - Free hemoglobin enhances tumor necrosis factor-alpha production in isolated human monocytesEddy H Carrillo
Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA
J Trauma 52:449-52. 2002.... - Tertiary care centers: a strategy for fiscal survivalJorge L Rodriguez
Department of Surgery, University of Louisville, Louisville, KY 40201, USA
Surgery 134:684-9; discussion 689-90. 2003..It also excludes the negative impact of increasing severity of illness and volume and should induce cost control... - Conference workgroups and summation. Dialogue from the Symposium on Challenges in Surgical Education: Competencies, Work Hours, Workforce, Assessment, and AdaptationHiram C Polk
Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, USA
Am J Surg 184:225-51. 2002 - A study of added costs of laparoscopic cholecystectomy based on surgery preference cardsJeff W Allen
Department of Surgery, University of Louisville, Kentucky 40292, USA
Am Surg 68:474-6. 2002..Our study points out the differences in expenses between surgeons. Maintaining this type of expense tracking can apply to other procedures and is a good place to start a surgeon-led and hospital-based cost-saving initiative... - Interferon-gamma gene polymorphisms and the development of sepsis in patients with traumaNicole A Stassen
Department of Surgery, Price Institute of Surgical Research, University of Louisville School of Medicine, KY 40202, USA
Surgery 132:289-92. 2002..This study evaluates the relationship between polymorphisms in the first intron of the interferon-gamma gene and the development of sepsis after trauma... - Emergence of resistant microbes in critical care units is transient, despite an unrestricted formulary and multiple antibiotic trialsGlen A Franklin
Department of Surgery, University of Louisville, Louisville, KY 40292, USA
Surg Infect (Larchmt) 3:135-44. 2002..This suggests that a policy of administering limited duration, narrow spectrum antibiotics may reduce drug resistance... - The fate and growth of general surgery in the United StatesHiram C Polk
Langenbecks Arch Surg 387:63-6. 2002 - The health workforce: a position statementJay L Grosfeld
American Surgical Association, USA
Ann Surg 246:525-6. 2007 - A neighbor's perspective on Josef E. FischerHiram C Polk
Am J Surg 183:489-90. 2002 - Pharmacoeconomics for surgeonsHiram C Polk
Am J Surg 183:1. 2002 - Continuing refinements in surgical antibiotic prophylaxisHiram C Polk
Arch Surg 140:1066-7. 2005 - Keeping score and the application of known principlesHiram C Polk
Am J Surg 190:16-7. 2005