M A Poles

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint HIV-Related hepatic disease: when and why to biopsy
    M A Poles
    Center for HIV and Digestive Diseases, Division of Digestive Diseases, University of California, Los Angeles School of Medicine, Los Angeles, California 90095, USA
    Gastrointest Endosc Clin N Am 8:939-62. 1998
  2. ncbi request reprint Hepatitis C virus/human immunodeficiency virus coinfection: clinical management issues
    M A Poles
    Division of Digestive Diseases, Center for HIV and Digestive Diseases, and University of California Los Angeles AIDS Institute, Los Angeles, CA, USA
    Clin Infect Dis 31:154-61. 2000
  3. ncbi request reprint Despite high concordance, distinct mutational and phenotypic drug resistance profiles in human immunodeficiency virus type 1 RNA are observed in gastrointestinal mucosal biopsy specimens and peripheral blood mononuclear cells compared with plasma
    M A Poles
    School of Medicine, Department of Medicine, University of California Los Angeles UCLA Center for HIV and Digestive Diseases and UCLA AIDS Institute, Los Angeles, CA 90095, USA
    J Infect Dis 183:143-8. 2001
  4. pmc A preponderance of CCR5(+) CXCR4(+) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection
    M A Poles
    Department of Medicine, UCLA School of Medicine, UCLA Center for HIV and Digestive Diseases, Los Angeles, California 90095, USA
    J Virol 75:8390-9. 2001
  5. ncbi request reprint Sensitive and reproducible quantitation of mucosal HIV-1 RNA and DNA viral burden in patients with detectable and undetectable plasma viral HIV-1 RNA using endoscopic biopsies
    P A Anton
    Division of Digestive Diseases, Department of Medicine, MRL 2734, UCLA School of Medicine, 675 Charles E Young Drive South, Los Angeles, CA 90095, USA
    J Virol Methods 95:65-79. 2001
  6. ncbi request reprint Diarrheal diseases associated with HIV infection
    E A Lew
    Department of Medicine, UCLA Medical Center, USA
    Gastroenterol Clin North Am 26:259-90. 1997
  7. ncbi request reprint HIV-related diarrhea is multifactorial and fat malabsorption is commonly present, independent of HAART
    M A Poles
    UCLA Center for HIV and Digestive Diseases, UCLA School of Medicine, Los Angeles, California 90095, USA
    Am J Gastroenterol 96:1831-7. 2001

Research Grants

  1. HIV MUCOSAL PATHOGENESIS IN PRIMARY INFECTION
    Michael Poles; Fiscal Year: 2003

Detail Information

Publications7

  1. ncbi request reprint HIV-Related hepatic disease: when and why to biopsy
    M A Poles
    Center for HIV and Digestive Diseases, Division of Digestive Diseases, University of California, Los Angeles School of Medicine, Los Angeles, California 90095, USA
    Gastrointest Endosc Clin N Am 8:939-62. 1998
    ..Care of these patients demands systematic evaluation and treatment to ensure that morbidity and mortality are minimized and quality of life and medical care costs are optimized...
  2. ncbi request reprint Hepatitis C virus/human immunodeficiency virus coinfection: clinical management issues
    M A Poles
    Division of Digestive Diseases, Center for HIV and Digestive Diseases, and University of California Los Angeles AIDS Institute, Los Angeles, CA, USA
    Clin Infect Dis 31:154-61. 2000
    ....
  3. ncbi request reprint Despite high concordance, distinct mutational and phenotypic drug resistance profiles in human immunodeficiency virus type 1 RNA are observed in gastrointestinal mucosal biopsy specimens and peripheral blood mononuclear cells compared with plasma
    M A Poles
    School of Medicine, Department of Medicine, University of California Los Angeles UCLA Center for HIV and Digestive Diseases and UCLA AIDS Institute, Los Angeles, CA 90095, USA
    J Infect Dis 183:143-8. 2001
    ..Despite significant concordance among compartments, mucosal- and PBMC-derived viral RNA showed instances of discordance with plasma-derived virus that may suggest compartmentalization of virus...
  4. pmc A preponderance of CCR5(+) CXCR4(+) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection
    M A Poles
    Department of Medicine, UCLA School of Medicine, UCLA Center for HIV and Digestive Diseases, Los Angeles, California 90095, USA
    J Virol 75:8390-9. 2001
    ..We conclude that, based on these findings, the gastrointestinal mucosa represents a favored target for HIV-1, in part due to its large population of CXCR4(+) CCR5(+) target cells and not to differences in the virus that it contains...
  5. ncbi request reprint Sensitive and reproducible quantitation of mucosal HIV-1 RNA and DNA viral burden in patients with detectable and undetectable plasma viral HIV-1 RNA using endoscopic biopsies
    P A Anton
    Division of Digestive Diseases, Department of Medicine, MRL 2734, UCLA School of Medicine, 675 Charles E Young Drive South, Los Angeles, CA 90095, USA
    J Virol Methods 95:65-79. 2001
    ....
  6. ncbi request reprint Diarrheal diseases associated with HIV infection
    E A Lew
    Department of Medicine, UCLA Medical Center, USA
    Gastroenterol Clin North Am 26:259-90. 1997
    ..This article reviews our current understanding of these pathogens and some of the diagnostic and therapeutic approaches for diarrhea associated with HIV infection...
  7. ncbi request reprint HIV-related diarrhea is multifactorial and fat malabsorption is commonly present, independent of HAART
    M A Poles
    UCLA Center for HIV and Digestive Diseases, UCLA School of Medicine, Los Angeles, California 90095, USA
    Am J Gastroenterol 96:1831-7. 2001
    ..Fecal fat determination should be considered a routine part of the diagnostic workup of HIV-infected patients experiencing diarrhea...

Research Grants2

  1. HIV MUCOSAL PATHOGENESIS IN PRIMARY INFECTION
    Michael Poles; Fiscal Year: 2003
    ..abstract_text> ..