Scott M Plafker

Summary

Affiliation: University of Oklahoma Health Sciences Center
Country: USA

Publications

  1. pmc Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import
    Scott M Plafker
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Cell Biol 167:649-59. 2004
  2. doi request reprint Oxidative stress and the ubiquitin proteolytic system in age-related macular degeneration
    Scott M Plafker
    University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Adv Exp Med Biol 664:447-56. 2010
  3. pmc The ubiquitin-conjugating enzyme UbcM2 can regulate the stability and activity of the antioxidant transcription factor Nrf2
    Kendra S Plafker
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    J Biol Chem 285:23064-74. 2010
  4. pmc The ubiquitin conjugating enzyme, UbcM2, engages in novel interactions with components of cullin-3 based E3 ligases
    Kendra S Plafker
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Biochemistry 48:3527-37. 2009
  5. pmc The human ubiquitin conjugating enzyme, UBE2E3, is required for proliferation of retinal pigment epithelial cells
    Kendra S Plafker
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
    Invest Ophthalmol Vis Sci 49:5611-8. 2008
  6. pmc Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina
    Saima Mirza
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Mol Vis 16:2425-37. 2010
  7. pmc Mechanisms for countering oxidative stress and damage in retinal pigment epithelium
    Scott M Plafker
    Free Radical Biology and Aging Program, Oklahoma Medical Research Foundation, Oklahoma City, USA
    Int Rev Cell Mol Biol 298:135-77. 2012
  8. pmc High dietary fat selectively increases catalase expression within cardiac mitochondria
    Paul M Rindler
    Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    J Biol Chem 288:1979-90. 2013
  9. pmc Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell-cell fusion
    Lulin Hu
    Department of Cell Biology, University of Oklahoma, Health Sciences Center, Oklahoma City, OK 73190, USA
    Virology 384:125-34. 2009

Collaborators

Detail Information

Publications9

  1. pmc Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import
    Scott M Plafker
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Cell Biol 167:649-59. 2004
    ..Together, these findings reveal that Ub charging can function as a nuclear import trigger, and identify a novel link between E2 regulation and karyopherin-mediated transport...
  2. doi request reprint Oxidative stress and the ubiquitin proteolytic system in age-related macular degeneration
    Scott M Plafker
    University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Adv Exp Med Biol 664:447-56. 2010
    ..Finally, we discuss how the UPS modulates the stability and activity of Nrf2, the major anti-oxidant transcription factor in the retina...
  3. pmc The ubiquitin-conjugating enzyme UbcM2 can regulate the stability and activity of the antioxidant transcription factor Nrf2
    Kendra S Plafker
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    J Biol Chem 285:23064-74. 2010
    ..This work implicates UbcM2 in the restoration of redox homeostasis following oxidative stress...
  4. pmc The ubiquitin conjugating enzyme, UbcM2, engages in novel interactions with components of cullin-3 based E3 ligases
    Kendra S Plafker
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Biochemistry 48:3527-37. 2009
    ..Together, these studies represent the first evidence that UbcM2, in concert with substrate adaptors, engages activated CUL3 ligases, thus suggesting that class III E2s are novel regulators of cullin ligases...
  5. pmc The human ubiquitin conjugating enzyme, UBE2E3, is required for proliferation of retinal pigment epithelial cells
    Kendra S Plafker
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
    Invest Ophthalmol Vis Sci 49:5611-8. 2008
    ..This study was undertaken to determine whether the human ubiquitin-conjugating enzyme, UBE2E3, is essential for RPE cell proliferation...
  6. pmc Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina
    Saima Mirza
    Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Mol Vis 16:2425-37. 2010
    ..These enzymes have been implicated in the ubiquitin-dependent degradation of oxidatively damaged and misfolded proteins...
  7. pmc Mechanisms for countering oxidative stress and damage in retinal pigment epithelium
    Scott M Plafker
    Free Radical Biology and Aging Program, Oklahoma Medical Research Foundation, Oklahoma City, USA
    Int Rev Cell Mol Biol 298:135-77. 2012
    ....
  8. pmc High dietary fat selectively increases catalase expression within cardiac mitochondria
    Paul M Rindler
    Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    J Biol Chem 288:1979-90. 2013
    ....
  9. pmc Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell-cell fusion
    Lulin Hu
    Department of Cell Biology, University of Oklahoma, Health Sciences Center, Oklahoma City, OK 73190, USA
    Virology 384:125-34. 2009
    ..Expression of HPV16 E6/E7 also increases bi-nucleated cell colony formation. These findings identify a new role for HPV16 E5 and support a model in which complementary roles of the HPV16 oncogenes lead to the induction of carcinogenesis...