Research Topics
Species | J PivenSummaryAffiliation: University of Iowa Country: USA Publications
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Detail Information
Publications
Psychiatric disorder and the broad autism phenotype: evidence from a family study of multiple-incidence autism familiesJ Piven
Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242 1000, USA
Am J Psychiatry 156:557-63. 1999..In this study the authors examined the rate of axis I psychiatric disorders in nonautistic relatives from multiple-incidence autism families and the possible relationship of these disorders to the broad autism phenotype...
Examination of AVPR1a as an autism susceptibility geneT H Wassink
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA 52242, USA
Mol Psychiatry 9:968-72. 2004..Given the emerging biological, animal model, and now genetic data, AVPR1a and genes in the AVP system remain strong candidates for involvement in autism susceptibility and deserve continued scrutiny...
Broader autism phenotype: evidence from a family history study of multiple-incidence autism familiesJ Piven
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, USA
Am J Psychiatry 154:185-90. 1997..The objective of this study was to examine behaviors that may define this broader phenotype in relatives ascertained through two autistic siblings...
Chromosomal abnormalities in a clinic sample of individuals with autistic disorderT H Wassink
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, USA
Psychiatr Genet 11:57-63. 2001..These data support the contribution of chromosomal abnormalities to a small but significant number of cases of autism, and highlight the involvement of chromosome 15 and the sex chromosomes...
Evidence supporting WNT2 as an autism susceptibility geneT H Wassink
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
Am J Med Genet 105:406-13. 2001....
The biological basis of autismJ Piven
Department of Psychiatry, University of Iowa College of Medicine, Psychiatry Research, Medical Education Building, Room 1 293, Iowa City, Iowa 52242, USA
Curr Opin Neurobiol 7:708-12. 1997..The results of these studies are likely to have a significant impact on our understanding of the pathogenesis of autism...
Incorporating language phenotypes strengthens evidence of linkage to autismY Bradford
Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA
Am J Med Genet 105:539-47. 2001..Although based on our data, we were not able to distinguish between epistasis or heterogeneity models, we tentatively concluded that there may be more than one autism susceptibility locus related to language development...
An autosomal genomic screen for autism. Collaborative linkage study of autismS Barrett
The Johns Hopkins University School of Medicine, Baltimore, Maryland
Am J Med Genet 88:609-15. 1999..By comparing results across a number of studies, we expect to be able to narrow our search for autism susceptibility genes to a small number of genomic regions. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:609-615, 1999...
Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism familiesE L Nurmi
Program in Human Genetics, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Genomics 77:105-13. 2001....
The broad autism phenotype: a complementary strategy for molecular genetic studies of autismJ Piven
North Carolina Mental Retardation and Developmental Disabilities Research Center, University of North Carolina at Chapel Hill, 27599-7250, USA
Am J Med Genet 105:34-5. 2001..Inclusion of information on the broad autism phenotype in relatives, in linkage studies of autism, may provide a potentially important, complementary approach for detecting the genes causing this condition...
Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in miceS S Moy
North Carolina STAART Center for Autism Research, Neurodevelopmental Disorders Research Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
Genes Brain Behav 3:287-302. 2004..This new standardized procedure to quantitate sociability and preference for social novelty in mice provides a method to assess tendencies for social avoidance in mouse models of autism...
