Genomes and Genes
Affiliation: University of California
- Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowthRoxana Pincheira
The Department of Surgery and the Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA or
EMBO J 28:261-73. 2009..These data establish Sall2 as a link between NTRs and transcriptional events that regulate the growth and development of neuronal cells...
- The Sall2 transcription factor is a novel p75NTR binding protein that promotes the development and function of neuronsRoxana Pincheira
The Department of Surgery and the Helen Diller Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA 94115, USA
Ann N Y Acad Sci 1144:53-5. 2008..Nuclear Sall2 activates target genes that modulate the growth and development of neurons. Thus, one way that p75NTR and TrkA can modulate the functions of neurons is by regulating the localization and actions of Sall2...
- Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activityRoxana Pincheira
Department of Surgery and Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
J Immunol 181:1288-98. 2008..These observations show that TNFR1 associates with and uses nonreceptor tyrosine kinases to engage signaling pathways, activate transcription factors, and modulate gene expression in cells...