Research Topics
Genomes and Genes | Roxana PincheiraSummaryAffiliation: University of California Country: USA Publications
| Collaborators
|
Detail Information
Publications
Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activityRoxana Pincheira
Department of Surgery and Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
J Immunol 181:1288-98. 2008..These observations show that TNFR1 associates with and uses nonreceptor tyrosine kinases to engage signaling pathways, activate transcription factors, and modulate gene expression in cells...
The Sall2 transcription factor is a novel p75NTR binding protein that promotes the development and function of neuronsRoxana Pincheira
The Department of Surgery and the Helen Diller Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA 94115, USA
Ann N Y Acad Sci 1144:53-5. 2008..Nuclear Sall2 activates target genes that modulate the growth and development of neurons. Thus, one way that p75NTR and TrkA can modulate the functions of neurons is by regulating the localization and actions of Sall2...
Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowthRoxana Pincheira
The Department of Surgery and the Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA or
EMBO J 28:261-73. 2009..These data establish Sall2 as a link between NTRs and transcriptional events that regulate the growth and development of neuronal cells...
Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activationJason A Gustin
Department of Microbiology and Immunology and Walther Oncology Center, Indiana University School of Medicine, 950 West Walnut Street, Indianapolis, IN 46202, USA
J Biol Chem 279:1615-20. 2004..Thus, noncoordinate expression of I kappa B kinases plays a role in determining the cell type-specific role of Akt in NF-kappa B activation...
Tumor necrosis factor activates CRE-binding protein through a p38 MAPK/MSK1 signaling pathway in endothelial cellsJason A Gustin
Department of Microbiology and Immunology, Indiana University School of Medicine, and the Walther Cancer Institute, Indianapolis, Indiana 46202, USA
Am J Physiol Cell Physiol 286:C547-55. 2004..These observations show that CREB is activated by TNF/TNFR1 signaling through a p38MAPK/MSK1 signaling pathway...
Role of eIF3 p170 in controlling synthesis of ribonucleotide reductase M2 and cell growthZizheng Dong
Department of Pharmacology and Toxicology, Indiana University Cancer Center, Walther Oncology Center/Walther Cancer Institute, Indiana University School of Medicine, 1044 W. Walnut Street, R4-166, Indianapolis, IN 46202, USA
Oncogene 23:3790-801. 2004....
Akt regulates basal and induced processing of NF-kappaB2 (p100) to p52Jason A Gustin
Department of Microbiology and Immunology and Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Biol Chem 281:16473-81. 2006..These observations show that Akt plays a role in activation of basal and induced non-canonical NF-kappaB activity...
Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminaseMinati Satpathy
Department of Medicine, Indiana University School of Medicine, 535 Barnhill Drive, RT 473, Indianapolis, IN 46202, USA
Cancer Res 67:7194-202. 2007..Highly expressed in ovarian tumors, TG2 facilitates i.p. tumor dissemination by enhancing cell adhesion to the extracellular matrix and modulating beta(1) integrin subunit expression...
