Satish K Pillai

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Expression profile of host restriction factors in HIV-1 elite controllers
    Mohamed Abdel-Mohsen
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    Retrovirology 10:106. 2013
  2. pmc Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo
    Satish K Pillai
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 109:3035-40. 2012
  3. ncbi request reprint Genetic attributes of cerebrospinal fluid-derived HIV-1 env
    Satish K Pillai
    University of California San Diego, Department of Medicine NCIRE, La Jolla, CA 94121, USA
    Brain 129:1872-83. 2006
  4. pmc Turning up the volume on mutational pressure: is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3)
    Satish K Pillai
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    Retrovirology 5:26. 2008
  5. pmc Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations
    Davey M Smith
    University of California San Diego, La Jolla, 92093, USA
    Virology 385:204-8. 2009
  6. pmc Effects of alpha interferon treatment on intrinsic anti-HIV-1 immunity in vivo
    Mohamed Abdel-Mohsen
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    J Virol 88:763-7. 2014
  7. pmc Select host restriction factors are associated with HIV persistence during antiretroviral therapy
    Mohamed Abdel-Mohsen
    aBlood Systems Research Institute, San Francisco bDepartment of Medicine, University of California, San Francisco, California cEmory University, Atlanta, Georgia dUniversity of California, San Diego, La Jolla eVeterans Affairs San Diego Healthcare System, San Diego fDepartment of Laboratory Medicine, University of California, San Francisco, California, USA
    AIDS 29:411-20. 2015
  8. pmc Role of microRNA modulation in the interferon-α/ribavirin suppression of HIV-1 in vivo
    Mohamed Abdel-Mohsen
    Department of Medicine, University of California San Francisco, San Francisco, California, United States of America Blood Systems Research Institute, San Francisco, California, United States of America
    PLoS ONE 9:e109220. 2014
  9. ncbi request reprint Lack of neutralizing antibody response to HIV-1 predisposes to superinfection
    Davey M Smith
    University of California San Diego, La Jolla, CA 92093 0679, USA
    Virology 355:1-5. 2006
  10. pmc Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo
    Rui André Saraiva Raposo
    Division of Experimental Medicine, University of California San Francisco, San Francisco, California, USA Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA
    J Virol 88:11624-9. 2014

Detail Information

Publications20

  1. pmc Expression profile of host restriction factors in HIV-1 elite controllers
    Mohamed Abdel-Mohsen
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    Retrovirology 10:106. 2013
    ....
  2. pmc Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo
    Satish K Pillai
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 109:3035-40. 2012
    ....
  3. ncbi request reprint Genetic attributes of cerebrospinal fluid-derived HIV-1 env
    Satish K Pillai
    University of California San Diego, Department of Medicine NCIRE, La Jolla, CA 94121, USA
    Brain 129:1872-83. 2006
    ..Furthermore, neurological impairment may be influenced by mutations within the viral V3 loop sequence...
  4. pmc Turning up the volume on mutational pressure: is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3)
    Satish K Pillai
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    Retrovirology 5:26. 2008
    ..Rigorous testing of this hypothesis will have timely and critical implications for the therapeutic management of HIV/AIDS, and delve into the complexities underlying the induction of lethal mutagenesis in a viral pathogen...
  5. pmc Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations
    Davey M Smith
    University of California San Diego, La Jolla, 92093, USA
    Virology 385:204-8. 2009
    ....
  6. pmc Effects of alpha interferon treatment on intrinsic anti-HIV-1 immunity in vivo
    Mohamed Abdel-Mohsen
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    J Virol 88:763-7. 2014
    ..649; P < 0.016). Exogenous IFN-α induces supraphysiologic restriction factor expression associated with a pronounced decrease in HIV-1 viremia. ..
  7. pmc Select host restriction factors are associated with HIV persistence during antiretroviral therapy
    Mohamed Abdel-Mohsen
    aBlood Systems Research Institute, San Francisco bDepartment of Medicine, University of California, San Francisco, California cEmory University, Atlanta, Georgia dUniversity of California, San Diego, La Jolla eVeterans Affairs San Diego Healthcare System, San Diego fDepartment of Laboratory Medicine, University of California, San Francisco, California, USA
    AIDS 29:411-20. 2015
    ..We sought to determine the impact of cell-intrinsic immunity on the HIV latent reservoir...
  8. pmc Role of microRNA modulation in the interferon-α/ribavirin suppression of HIV-1 in vivo
    Mohamed Abdel-Mohsen
    Department of Medicine, University of California San Francisco, San Francisco, California, United States of America Blood Systems Research Institute, San Francisco, California, United States of America
    PLoS ONE 9:e109220. 2014
    ....
  9. ncbi request reprint Lack of neutralizing antibody response to HIV-1 predisposes to superinfection
    Davey M Smith
    University of California San Diego, La Jolla, CA 92093 0679, USA
    Virology 355:1-5. 2006
    ..These data have considerable implications for vaccine development...
  10. pmc Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo
    Rui André Saraiva Raposo
    Division of Experimental Medicine, University of California San Francisco, San Francisco, California, USA Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA
    J Virol 88:11624-9. 2014
    ..Our data are among the first to demonstrate the dynamic nature of host restriction factors in vivo over time...
  11. pmc Semen-specific genetic characteristics of human immunodeficiency virus type 1 env
    Satish K Pillai
    University of California, San Diego, Division of Biological Sciences, 9500 Gilman Dr, MC 0679, La Jolla, CA 92093, USA
    J Virol 79:1734-42. 2005
    ..Our analysis suggests that the male genital tract represents a distinct selective environment that contributes to the apparent genetic bottlenecks associated with the sexual transmission of HIV-1...
  12. pmc Protease polymorphisms in HIV-1 subtype CRF01_AE represent selection by antiretroviral therapy and host immune pressure
    Weerawat Manosuthi
    University of California San Diego, La Jolla, California, USA
    AIDS 24:411-6. 2010
    ..We investigated the effect of protease resistance-associated mutations (PRAMs) and population-based HLA haplotype frequencies on polymorphisms found in CRF01_AE pro...
  13. pmc Effects of cellular activation on anti-HIV-1 restriction factor expression profile in primary cells
    Rui André Saraiva Raposo
    Division of Experimental Medicine, University of California San Francisco, San Francisco, California, USA
    J Virol 87:11924-9. 2013
    ..This report demonstrates synchronous effects of activation-induced antiviral genes on HIV-1 infectivity, providing candidates for pharmacological manipulation. ..
  14. pmc Increased expression of intrinsic antiviral genes in HLA-B*57-positive individuals
    Rui André Saraiva Raposo
    2 Division of Experimental Medicine, 1001 Potrero Ave, Bldg 3, Room 603, Box 1234, San Francisco, CA 94110, USA
    J Leukoc Biol 94:1051-9. 2013
    ..Our results provide insights into natural protection mechanisms and immunity against HIV-1 that fall outside of classical HLA-mediated effects. ..
  15. pmc BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-action
    Mark Skasko
    Department of Pathology, University of California San Diego, La Jolla, CA 92093 0679, USA
    Virology 411:65-77. 2011
    ....
  16. pmc Inferring HIV transmission dynamics from phylogenetic sequence relationships
    Christopher D Pilcher
    University of California San Francisco, San Francisco, California, United States of America
    PLoS Med 5:e69. 2008
  17. pmc In vivo CD8+ T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells
    Joseph K Wong
    Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS Pathog 6:e1000748. 2010
    ..These observations have important implications for future strategies to augment immune control of HIV...
  18. ncbi request reprint Codon volatility does not reflect selective pressure on the HIV-1 genome
    Satish K Pillai
    University of California, San Diego, Stein Clinical Research Building, Room 325, 9500 Gilman Drive 0679, La Jolla 92093, USA
    Virology 336:137-43. 2005
    ..Volatility failed to correlate with the results of any of the comparative methods demonstrating that it is not a reliable indicator of selection pressure...
  19. pmc Cross-sectional dating of novel haplotypes of HERV-K 113 and HERV-K 115 indicate these proviruses originated in Africa before Homo sapiens
    Aashish R Jha
    Division of Experimental Medicine, University of California San Francisco, CA, USA
    Mol Biol Evol 26:2617-26. 2009
    ..Using our method, we estimated the insertion dates of K113 and K115 to be a minimum of 800,000 and 1.1 million years ago, respectively. Both these insertion dates predate the emergence of anatomically modern Homo sapiens...
  20. pmc Interferon-alpha drives monocyte gene expression in chronic unsuppressed HIV-1 infection
    Hans Rempel
    Department of Laboratory Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    AIDS 24:1415-23. 2010
    ..The objectives were two fold: to characterize the impact of HIV-1 infection on peripheral monocyte gene expression and to identify the predominant factor(s) responsible for altered gene expression...