Catherine Pihoker

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Autoantibodies in diabetes
    Catherine Pihoker
    Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA
    Diabetes 54:S52-61. 2005
  2. pmc Correlates of treatment patterns among youth with type 2 diabetes
    Angela Badaru
    Corresponding author Catherine Pihoker
    Diabetes Care 37:64-72. 2014
  3. pmc Prevalence, characteristics and clinical diagnosis of maturity onset diabetes of the young due to mutations in HNF1A, HNF4A, and glucokinase: results from the SEARCH for Diabetes in Youth
    Catherine Pihoker
    MD, Department of Pediatrics Division of Endocrinology, A5902, Seattle Children s Hospital, 4800 Sand Point Way NE, Seattle, Washington 98105
    J Clin Endocrinol Metab 98:4055-62. 2013
  4. pmc Insulin regimens and clinical outcomes in a type 1 diabetes cohort: the SEARCH for Diabetes in Youth study
    Catherine Pihoker
    Department of Pediatrics, University of Washington, Seattle, WA, USA
    Diabetes Care 36:27-33. 2013
  5. ncbi request reprint What type of diabetes do young people have?
    Catherine Pihoker
    Department of Pediatrics, University of Washington, Box 359300, M1 3, Seattle, WA 98105, USA
    Curr Diab Rep 6:108-12. 2006
  6. doi request reprint CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope
    Junbao Yang
    Benaroya Research Institute at Virginia Mason, 1201 Ninth Ave, Seattle, WA 98101, USA
    J Autoimmun 31:30-41. 2008
  7. doi request reprint Predictors of insulin regimens and impact on outcomes in youth with type 1 diabetes: the SEARCH for Diabetes in Youth study
    Carolyn A Paris
    University of Washington, Seattle, WA, USA
    J Pediatr 155:183-9.e1. 2009
  8. doi request reprint Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth study
    Lenna L Liu
    Center for Child Health, Behavior, and Development, Seattle Children s Hospital Research Institute, Seattle, WA 98101, USA
    Pediatr Diabetes 11:4-11. 2010
  9. ncbi request reprint Autoimmunity and clinical course in children with type 1, type 2, and type 1.5 diabetes
    Lisa K Gilliam
    Department of Medicine, University of Washington, 1959 N E Pacific St, Box 357710, Seattle, 98195, USA
    J Autoimmun 25:244-50. 2005
  10. pmc Preservation of beta-cell function in autoantibody-positive youth with diabetes
    Carla J Greenbaum
    Diabetes Research Program, Benaroya Research Institute, Seattle, Washington, USA
    Diabetes Care 32:1839-44. 2009

Research Grants

  1. SEARCH for Diabetes in Youth 2: Washington Site
    Catherine Pihoker; Fiscal Year: 2007

Detail Information

Publications41

  1. ncbi request reprint Autoantibodies in diabetes
    Catherine Pihoker
    Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA
    Diabetes 54:S52-61. 2005
    ..Autoantibodies may also provide prognostic information in clinically heterogeneous patient populations when examined longitudinally...
  2. pmc Correlates of treatment patterns among youth with type 2 diabetes
    Angela Badaru
    Corresponding author Catherine Pihoker
    Diabetes Care 37:64-72. 2014
    ..Those with longer diabetes duration in particular commonly experienced treatment failures, and more effective management strategies are needed. ..
  3. pmc Prevalence, characteristics and clinical diagnosis of maturity onset diabetes of the young due to mutations in HNF1A, HNF4A, and glucokinase: results from the SEARCH for Diabetes in Youth
    Catherine Pihoker
    MD, Department of Pediatrics Division of Endocrinology, A5902, Seattle Children s Hospital, 4800 Sand Point Way NE, Seattle, Washington 98105
    J Clin Endocrinol Metab 98:4055-62. 2013
    ....
  4. pmc Insulin regimens and clinical outcomes in a type 1 diabetes cohort: the SEARCH for Diabetes in Youth study
    Catherine Pihoker
    Department of Pediatrics, University of Washington, Seattle, WA, USA
    Diabetes Care 36:27-33. 2013
    ..To examine the patterns and associations of insulin regimens and change in regimens with clinical outcomes in a diverse population of children with recently diagnosed type 1 diabetes...
  5. ncbi request reprint What type of diabetes do young people have?
    Catherine Pihoker
    Department of Pediatrics, University of Washington, Box 359300, M1 3, Seattle, WA 98105, USA
    Curr Diab Rep 6:108-12. 2006
    ....
  6. doi request reprint CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope
    Junbao Yang
    Benaroya Research Institute at Virginia Mason, 1201 Ninth Ave, Seattle, WA 98101, USA
    J Autoimmun 31:30-41. 2008
    ..These data suggest that T cells from type 1 diabetic subjects have a lower threshold of activation in response to PPI peptide stimulation as compared to healthy subjects...
  7. doi request reprint Predictors of insulin regimens and impact on outcomes in youth with type 1 diabetes: the SEARCH for Diabetes in Youth study
    Carolyn A Paris
    University of Washington, Seattle, WA, USA
    J Pediatr 155:183-9.e1. 2009
    ....
  8. doi request reprint Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth study
    Lenna L Liu
    Center for Child Health, Behavior, and Development, Seattle Children s Hospital Research Institute, Seattle, WA 98101, USA
    Pediatr Diabetes 11:4-11. 2010
    ....
  9. ncbi request reprint Autoimmunity and clinical course in children with type 1, type 2, and type 1.5 diabetes
    Lisa K Gilliam
    Department of Medicine, University of Washington, 1959 N E Pacific St, Box 357710, Seattle, 98195, USA
    J Autoimmun 25:244-50. 2005
    ..We examined the relationship between diabetes autoantibodies (DAA), human leukocyte antigen (HLA), and clinical course in subjects grouped by clinical diabetes type...
  10. pmc Preservation of beta-cell function in autoantibody-positive youth with diabetes
    Carla J Greenbaum
    Diabetes Research Program, Benaroya Research Institute, Seattle, Washington, USA
    Diabetes Care 32:1839-44. 2009
    ..To determine the extent of beta-cell function in youth with diabetes and GAD65 and/or IA2 autoantibodies...
  11. doi request reprint Transition from pediatric to adult care for youth diagnosed with type 1 diabetes in adolescence
    Debra S Lotstein
    Department of Pediatrics, David Geffen School of Medicine at UCLA, Box 951752, 22 464 MDCC, Los Angeles, CA 90095 1752, USA
    Pediatrics 131:e1062-70. 2013
    ....
  12. pmc Change in mean transit time, apparent diffusion coefficient, and cerebral blood volume during pediatric diabetic ketoacidosis treatment
    Monica S Vavilala
    Department of Anesthesiology, University of Washington, Seattle, WA, USA
    Pediatr Crit Care Med 12:e344-9. 2011
    ..We examined measures describing potential causes of whole brain and regional brain edema (mean transit time, apparent diffusion coefficient, and relative cerebral blood volume) during treatment of diabetic ketoacidosis in children...
  13. pmc Hypertension despite dehydration during severe pediatric diabetic ketoacidosis
    Kristina H Deeter
    Department of Pediatrics, Seattle Children s Hospital, University of Washington, Seattle, WA, USA
    Pediatr Diabetes 12:295-301. 2011
    ..Diabetic ketoacidosis (DKA) may result in both dehydration and cerebral edema but these processes may have opposing effects on blood pressure. We examined the relationship between dehydration and blood pressure in pediatric DKA...
  14. pmc Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects
    S Alice Long
    Benaroya Research Institute at Virginia Mason, Seattle, Washington, USA
    Diabetes 59:407-15. 2010
    ..Here, we address whether altered IL-2 responsiveness impacts persistence of FOXP3 expression in Tregs of type 1 diabetic subjects...
  15. pmc Prevalence and determinants of elevated apolipoprotein B and dense low-density lipoprotein in youths with type 1 and type 2 diabetes
    John J Albers
    Department of Medicine, Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, 401 Queen Anne Avenue North, Seattle, Washington 98109, USA
    J Clin Endocrinol Metab 93:735-42. 2008
    ..The objective of the study was to assess the prevalence and determinants of elevated apolipoprotein B (apoB) and dense low-density lipoprotein (LDL) in United States youth with type 1 or type 2 diabetes...
  16. ncbi request reprint Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study
    Arleta Rewers
    Department of Pediatrics, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA
    Pediatrics 121:e1258-66. 2008
    ..The purpose of this work was to determine the prevalence and predictors of diabetic ketoacidosis at the diagnosis of diabetes in a large sample of youth from the US population...
  17. ncbi request reprint Family history of diabetes, autoimmunity, and risk factors for cardiovascular disease among children with diabetes in the SEARCH for Diabetes in Youth Study
    Lisa K Gilliam
    Department of Medicine, University of Washington, Seattle, WA 98195 7710, USA
    Pediatr Diabetes 8:354-61. 2007
    ....
  18. pmc Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects
    S Alice Long
    Benaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA
    Eur J Immunol 39:612-20. 2009
    ..Thus, these data suggest that development of functional adaptive Treg can occur in response to islet antigens and activation of islet-specific Treg may potentially be used as a targeted immunotherapy in T1D...
  19. doi request reprint Change in fractional anisotropy during treatment of diabetic ketoacidosis in children
    Leslie Dervan
    Department of Pediatrics, University of Washington, Seattle, Washington
    Pediatr Res 75:62-6. 2014
    ....
  20. pmc Glucocorticoids and insulin resistance in children with acute lymphoblastic leukemia
    Eric J Chow
    Department of Pediatrics, Seattle Children s Hospital, University of Washington, Seattle, Washington, USA
    Pediatr Blood Cancer 60:621-6. 2013
    ..Children treated for acute lymphoblastic leukemia (ALL) are more likely to become overweight. Prolonged exposure to high-dose glucocorticoids may cause insulin resistance and facilitate development of this phenotype...
  21. doi request reprint Type 2 diabetes in childhood: clinical characteristics and role of β-cell autoimmunity
    Angela Badaru
    Department of Pediatrics, University of Washington, Seattle, WA, USA
    Curr Diab Rep 12:75-81. 2012
    ..Current and future work should determine if the presence of autoantibodies in phenotypic T2DM youth/children affects clinical course; this will facilitate the development of optimal treatment strategies...
  22. ncbi request reprint Evaluation of leptin levels in subjects at risk for type 1 diabetes
    Lisa K Gilliam
    Department of Medicine, University of Washington, Seattle, WA 98195 7710, USA
    J Autoimmun 26:133-7. 2006
    ....
  23. pmc The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells
    Anya Schneider
    Benaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA
    J Immunol 181:7350-5. 2008
    ..This has implications with respect to pathogenic mechanisms, which underlie the development of disease and the target of therapies for T1D...
  24. ncbi request reprint Autoimmunity to islet proteins in children diagnosed with new-onset diabetes
    Barbara M Brooks-Worrell
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 89:2222-7. 2004
    ..Moreover, the presence of obesity or acanthosis nigracans does not reliably distinguish children with or without islet cell autoimmunity...
  25. pmc Comparison of mercury and aneroid blood pressure measurements in youth
    Amy S Shah
    Department of Pediatrics, Cincinnati Children s Hospital, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Pediatrics 129:e1205-10. 2012
    ..Despite this change, few studies have compared BP measurements between the 2 devices...
  26. pmc Complementary and alternative medicine use and quality of life in pediatric diabetes
    Rachelle L McCarty
    Bastyr University, School of Naturopathic Medicine, Kenmore, WA, USA
    J Altern Complement Med 16:165-73. 2010
    ..The objectives of this study were to explore the association between complementary and alternative medicine (CAM) use as reported by youth, and parents' and children's reported quality of life in youth with diabetes...
  27. pmc Change in blood-brain barrier permeability during pediatric diabetic ketoacidosis treatment
    Monica S Vavilala
    Department of Anesthesiology, University of Washington, Seattle, WA, USA
    Pediatr Crit Care Med 11:332-8. 2010
    ..Cerebral edema is a devastating complication of pediatric diabetic ketoacidosis. We aimed to examine blood-brain barrier permeability during treatment of diabetic ketoacidosis in children...
  28. ncbi request reprint Obesity and hypertension among children after treatment for acute lymphoblastic leukemia
    Eric J Chow
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Cancer 110:2313-20. 2007
    ..The purpose was to determine the prevalence and treatment-related risk factors for obesity and hypertension among childhood acute lymphoblastic leukemia (ALL) survivors treated with contemporary therapy...
  29. ncbi request reprint Type 2 diabetes in youth
    Lenna Liu
    Child Health Institute and Children s Hospital and Regional Medical Center, Seattle, Washington, USA
    Curr Probl Pediatr Adolesc Health Care 34:254-72. 2004
  30. doi request reprint Use of oral glucose minimal model-derived index of insulin sensitivity in subjects with early type 1 diabetes mellitus
    Kevin M Krudys
    Department of Bioengineering, Resource Facility for Population Kinetics, University of Washington, PO Box 355061, Seattle, WA 98195, USA
    Metabolism 57:445-7. 2008
    ..Given the simplicity of the OGTT relative to the traditional methods of measuring SI, the oral glucose minimal model may be appropriate for large population studies and clinical trials...
  31. ncbi request reprint Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects
    Junbao Yang
    Benaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA
    J Immunol 176:2781-9. 2006
    ....
  32. doi request reprint Correlation of TSH with the risk of paediatric thyroid carcinoma
    Harvey K Chiu
    Division of Endocrinology, Department of Pediatrics, Seattle Children s Hospital, University of Washington Medical Center, Seattle, Washington 98105, USA
    Clin Endocrinol (Oxf) 77:316-22. 2012
    ..No previous studies have correlated the paediatric thyroid cancer risk with TSH levels...
  33. ncbi request reprint Early childhood gender differences in anterior and posterior cerebral blood flow velocity and autoregulation
    Nuj Tontisirin
    Anesthesiology, University of Washington, Seattle, Washington, USA
    Pediatrics 119:e610-5. 2007
    ..We aimed to describe gender differences in blood flow velocity and autoregulation of the anterior and posterior cerebral circulations in prepubertal children...
  34. ncbi request reprint The case for intravenous arginine stimulation in lieu of mixed-meal tolerance tests as outcome measure for intervention studies in recent-onset type 1 diabetes
    Carla Greenbaum
    Benaroya Research Institute, Diabetes Clinical Research, Seattle, Washington 98101, USA
    Diabetes Care 27:1202-4. 2004
  35. ncbi request reprint Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives
    Nathan E Standifer
    Benaroya Research Institute at Virginia Mason, 1201 Ninth Ave, Room 260, Seattle WA, 98101, USA
    Diabetes 55:3061-7. 2006
    ..These data implicate peptides of ppIAPP, GFAP, and IGRP as CTL epitopes for a heterogenous CD8(+) T-cell response in type 1 subjects and antibody-positive relatives...
  36. ncbi request reprint Serum lipids and glucose control: the SEARCH for Diabetes in Youth study
    Diana B Petitti
    Department of Research and Evaluation, Kaiser Permanente Southern California, 393 E Walnut St, Pasadena, CA 91188, USA
    Arch Pediatr Adolesc Med 161:159-65. 2007
    ..To assess the relationship of serum lipid concentrations with glucose control in youth with diabetes mellitus...
  37. doi request reprint Health-related quality of life of children and adolescents with type 1 or type 2 diabetes mellitus: SEARCH for Diabetes in Youth Study
    Michelle J Naughton
    Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, 2000 W First St, Winston Salem, NC 27104, USA
    Arch Pediatr Adolesc Med 162:649-57. 2008
    ..To examine the associations between demographic and diabetes management variables and the health-related quality of life (HRQOL) of youths with type 1 or type 2 diabetes mellitus (DM)...
  38. ncbi request reprint Lipid abnormalities are prevalent in youth with type 1 and type 2 diabetes: the SEARCH for Diabetes in Youth Study
    Ann K Kershnar
    Research and Evaluation, Kaiser Permanente Southern California, 9449 East Imperial Highway, Downey, CA 90242, USA
    J Pediatr 149:314-9. 2006
    ..Assessment of the prevalence of serum lipid abnormalities in US youth with type 1 or type 2 diabetes...
  39. ncbi request reprint Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes
    Dana Dabelea
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    Diabetes Care 29:290-4. 2006
    ..The "accelerator hypothesis" predicts that fatness is associated with an earlier age at onset of type 1 diabetes. We tested the hypothesis using data from the SEARCH for Diabetes in Youth study...
  40. ncbi request reprint Dietary intake among youth with diabetes: the SEARCH for Diabetes in Youth Study
    Elizabeth J Mayer-Davis
    Center for Research in Nutrition and Health Disparities, University of South Carolina, Columbia, USA
    J Am Diet Assoc 106:689-97. 2006
    ..To describe dietary intake among a large cohort of youth with type 1 or type 2 diabetes and to compare their intake with current nutrition recommendations...
  41. ncbi request reprint Assessment and monitoring of glycemic control in children and adolescents with diabetes
    Marian Rewers
    Barbara Davis Center, University of Colorado Denver, Aurora, CO, USA
    Pediatr Diabetes 8:408-18. 2007

Research Grants2

  1. SEARCH for Diabetes in Youth 2: Washington Site
    Catherine Pihoker; Fiscal Year: 2007
    ..abstract_text> ..