Research Topics
Genomes and GenesSpecies | Sandrine V PierreSummaryAffiliation: University of Toledo Country: USA Publications
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Detail Information
Publications
Isoform specificity of Na-K-ATPase-mediated ouabain signalingSandrine V Pierre
Dept of Physiology and Pharmacology, Univ of Toledo College of Medicine, 3035 Arlington Ave, Toledo, OH 43614 5804, USA
Am J Physiol Renal Physiol 294:F859-66. 2008....
Modulation of Na(+)-K(+)-ATPase cell surface abundance through structural determinants on the α1-subunitSandrine V Pierre
Department of Physiology and Pharmacology, University of Toledo College of Medicine, Ohio 43614 2598, USA
Am J Physiol Cell Physiol 300:C42-8. 2011....
Modulation of cardiac Na+,K+-ATPase cell surface abundance by simulated ischemia-reperfusion and ouabain preconditioningAude Belliard
Department of Biochemistry, College of Medicine, University of Toledo, 3000 Arlington Ave, Toledo, OH 43614, USA
Am J Physiol Heart Circ Physiol 304:H94-103. 2013..They further suggest that the protection conferred by increased surface expression of Na(+),K(+)-ATPase may be independent of ion transport...
Different roles of the cardiac Na+/Ca2+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophyYan Bai
Department of Biochemistry and Cancer Biology, College of Medicine and Life Sciences, Univ of Toledo, 3000 Arlington Ave, MS 1010, Toledo, Ohio 43614, USA
Am J Physiol Heart Circ Physiol 304:H427-35. 2013....
Preconditioning by subinotropic doses of ouabain in the Langendorff perfused rabbit heartEric E Morgan
Department of Physiology and Pharmacology, College of Medicine, University of Toledo, Toledo, OH 43614 5804, USA
J Cardiovasc Pharmacol 55:234-9. 2010..These data indicate that ouabain administration activates the Na/K-ATPase signaling cascade and protects against ischemic injury in a species with high cardiac Na/K-ATPase sensitivity...
Alterations of Na+/K+-ATPase function in caveolin-1 knockout cardiac fibroblastsLuis E M Quintas
Department of Physiology and Pharmacology, College of Medicine, University of Toledo, Toledo, OH 43614 5804, USA
J Mol Cell Cardiol 49:525-31. 2010..While depletion of caveolae increases the pumping function of Na(+)/K(+)-ATPase, it suppresses CTS-induced signal transduction, growth, and collagen production in cardiac fibroblasts...
Critical role of the isoform-specific region in alpha1-Na,K-ATPase trafficking and protein Kinase C-dependent regulationYoann Sottejeau
Department of Physiology and Pharmacology, University of Toledo College of Medicine, Toledo, Ohio 43614, USA
Biochemistry 49:3602-10. 2010..These findings suggest that a dileucine motif embedded within the Na,K-ATPase alpha1-ISR plays a critical role in the surface expression of Na,K-ATPase alpha1 polypeptides at steady state and in the response to PKC activation...
Ouabain triggers preconditioning through activation of the Na+,K+-ATPase signaling cascade in rat heartsSandrine V Pierre
Department of Physiology, Pharmacology, Metabolism and Cardiovascular Sciences, Medical University of Ohio, 3035 Arlington Avenue, Toledo, OH 43614 5804, USA
Cardiovasc Res 73:488-96. 2007....
The Na,K-ATPase receptor complex: its organization and membershipSandrine V Pierre
Department of Physiology, Pharmacology, Metabolism and Cardiovascular Sciences, Medical University of Ohio, Toledo, OH 43614, USA
Cell Biochem Biophys 46:303-16. 2006..This article reviews these new developments and provides a comparison of Na,K-ATPase-mediated signal transduction with other receptors and ion transporters...
Association of PI3K-Akt signaling pathway with digitalis-induced hypertrophy of cardiac myocytesLijun Liu
Department of Physiology, Pharmacology, Metabolism, and Cardiovascular Sciences, The University of Toledo College of Medicine, Toledo, Ohio 43614 2598, USA
Am J Physiol Cell Physiol 293:C1489-97. 2007....
Involvement of Na+/K+-ATPase in hydrogen peroxide-induced hypertrophy in cardiac myocytesLijun Liu
Department of Physiology, Pharmacology, Metabolism and Cardiovascular Sciences, Medical University of Ohio, Toledo, OH 43614, USA
Free Radic Biol Med 41:1548-56. 2006..These results, taken together with our prior observations, suggest that ROS may cross talk with Na+/K+-ATPase, leading to the activation of hypertrophic pathways in cardiac myocytes...
Role of the isoform-specific region of the Na,K-ATPase catalytic subunitMarie Josee Duran
Department of Physiology, Texas Tech University Health Sciences Center, Lubbock 79430, USA
Ann N Y Acad Sci 986:258-9. 2003
Regions conferring isoform-specific function in the catalytic subunit of the Na,K-pumpThomas A Pressley
Department of Physiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
Front Biosci 10:2018-26. 2005....
Ouabain protects rat hearts against ischemia-reperfusion injury via pathway involving src kinase, mitoKATP, and ROSPhilippe Pasdois
Institut National de la Santé et de la Recherche, Médicale U441, University Victor Segalen Bordeaux 2, University Hospital of Bordeaux, Bordeaux, France
Am J Physiol Heart Circ Physiol 292:H1470-8. 2007..However, only PP2, 5-HD, and MPG blocked ouabain-induced cardioprotection...
Conditioning the heart induces formation of signalosomes that interact with mitochondria to open mitoKATP channelsCasey L Quinlan
Department of Biology, Portland State University, PO Box 751, Portland, OR 97201 0751, USA
Am J Physiol Heart Circ Physiol 295:H953-H961. 2008..These results provide initial support for a novel mechanism for signal transmission from a plasma membrane receptor to mitoKATP channels...
Structure/function analysis of Na(+)-K(+)-ATPase central isoform-specific region: involvement in PKC regulationSandrine V Pierre
Department of Physiology, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
Am J Physiol Renal Physiol 283:F1066-74. 2002..Comparisons with rat full-length alpha(1)- and alpha(2)-isoforms expressed under the same conditions suggest an involvement of the central ISR in the response to PKC but not in K(+) deocclusion...
