Lori Pierce

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi Effect of radiotherapy after breast-conserving treatment in women with breast cancer and germline BRCA1/2 mutations
    L J Pierce
    Department of Radiation Oncology, University of Michigan, and University of Michigan Cancer Center Biostatistics Core, Ann Arbor, MI, USA
    J Clin Oncol 18:3360-9. 2000
  2. ncbi The use of radiotherapy after mastectomy: a review of the literature
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    J Clin Oncol 23:1706-17. 2005
  3. ncbi Conservative surgery and radiotherapy for stage I/II breast cancer using lung density correction: 10-year and 15-year results
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    Int J Radiat Oncol Biol Phys 61:1317-27. 2005
  4. ncbi 1998-1999 patterns of care study process survey of national practice patterns using breast-conserving surgery and radiotherapy in the management of stage I-II breast cancer
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 62:183-92. 2005
  5. ncbi Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
    J Clin Oncol 24:2437-43. 2006
  6. ncbi Radiotherapy in the treatment of hereditary breast cancer
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
    Semin Radiat Oncol 21:43-50. 2011
  7. ncbi Postmastectomy radiotherapy of the chest wall: dosimetric comparison of common techniques
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 52:1220-30. 2002
  8. ncbi Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer: comparison of breast conservation and mastectomy
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, 1500 East Medical Center Drive Room 4308, Ann Arbor, MI 48109, USA
    Breast Cancer Res Treat 121:389-98. 2010
  9. ncbi Body mass index predicts the incidence of radiation pneumonitis in breast cancer patients
    Aaron M Allen
    Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA
    Cancer J 11:390-8. 2005
  10. ncbi Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breast
    Lawrence J Solin
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer 103:1137-46. 2005

Research Grants

  1. IMRT in the Treatment of Node-Positive Breast Cancer
    Lori Pierce; Fiscal Year: 2003
  2. IMRT in the Treatment of Node-Positive Breast Cancer
    Lori Pierce; Fiscal Year: 2006

Detail Information

Publications52

  1. ncbi Effect of radiotherapy after breast-conserving treatment in women with breast cancer and germline BRCA1/2 mutations
    L J Pierce
    Department of Radiation Oncology, University of Michigan, and University of Michigan Cancer Center Biostatistics Core, Ann Arbor, MI, USA
    J Clin Oncol 18:3360-9. 2000
    ....
  2. ncbi The use of radiotherapy after mastectomy: a review of the literature
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    J Clin Oncol 23:1706-17. 2005
  3. ncbi Conservative surgery and radiotherapy for stage I/II breast cancer using lung density correction: 10-year and 15-year results
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    Int J Radiat Oncol Biol Phys 61:1317-27. 2005
    ..Since 1984, we have used lung density correction for dose calculations at the University of Michigan. We now present our 10-year and 15-year results...
  4. ncbi 1998-1999 patterns of care study process survey of national practice patterns using breast-conserving surgery and radiotherapy in the management of stage I-II breast cancer
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 62:183-92. 2005
    ..The current 1998-1999 report updates the previous 1989 and 1993-1994 analyses and reflects the recent changes in surgery and systemic therapy observed nationally in the management of early-stage disease...
  5. ncbi Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
    J Clin Oncol 24:2437-43. 2006
    ..We compared the outcome of breast-conserving surgery and radiotherapy in BRCA1/2 mutation carriers with breast cancer versus that of matched sporadic controls...
  6. ncbi Radiotherapy in the treatment of hereditary breast cancer
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
    Semin Radiat Oncol 21:43-50. 2011
    ..Available reports on radiation-related outcomes in these and single nucleotide polymorphisms in radiation repair and response genes are discussed...
  7. ncbi Postmastectomy radiotherapy of the chest wall: dosimetric comparison of common techniques
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 52:1220-30. 2002
    ....
  8. ncbi Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer: comparison of breast conservation and mastectomy
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, 1500 East Medical Center Drive Room 4308, Ann Arbor, MI 48109, USA
    Breast Cancer Res Treat 121:389-98. 2010
    ..However, women undergoing BCT have an elevated risk of a second in-breast event that is significantly reduced in the presence of chemotherapy. Contralateral breast cancer events are very common...
  9. ncbi Body mass index predicts the incidence of radiation pneumonitis in breast cancer patients
    Aaron M Allen
    Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA
    Cancer J 11:390-8. 2005
    ..We herein present a case control study assessing the impact of clinical and dose-volume metrics on the development of radiation pneumonitis in patients receiving sequential chemotherapy and local-regional radiotherapy...
  10. ncbi Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breast
    Lawrence J Solin
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer 103:1137-46. 2005
    ..The objective of the current study was to determine the long-term outcome after breast-conservation surgery followed by definitive breast irradiation for women with mammographically detected DCIS of the breast...
  11. ncbi Variability of target and normal structure delineation for breast cancer radiotherapy: an RTOG Multi-Institutional and Multiobserver Study
    X Allen Li
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Int J Radiat Oncol Biol Phys 73:944-51. 2009
    ....
  12. ncbi Long-term results of conservative surgery and radiotherapy for ductal carcinoma in situ using lung density correction: the University of Michigan experience
    Merav A Ben David
    Department of Radiation Oncology, Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Breast J 13:392-400. 2007
    ....
  13. ncbi Radiotherapy for breast cancer in BRCA1/BRCA2 carriers: clinical issues and management dilemmas
    Lori Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA
    Semin Radiat Oncol 12:352-61. 2002
    ..The significant reduction in the incidence of breast cancer following bilateral prophylactic mastectomy is also discussed, as well as the potential for adverse psychological sequelae...
  14. ncbi Evaluation of multiple breathing states using a multiple instance geometry approximation (MIGA) in inverse-planned optimization for locoregional breast treatment
    Alexander Lin
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 72:610-6. 2008
    ..This study assessed whether optimization based on multiple instance geometry approximation (MIGA) could derive an IMRT plan that is less sensitive to known respiratory motions...
  15. ncbi Postmastectomy radiation therapy for patients with locally advanced breast cancer
    Reshma Jagsi
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 5010, USA
    Semin Radiat Oncol 19:236-43. 2009
    ..It concludes with a summary of consensus guideline recommendations in this important area...
  16. ncbi Statement of the science concerning locoregional treatments after preoperative chemotherapy for breast cancer: a National Cancer Institute conference
    Thomas A Buchholz
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcolmbe Blvd, Unit 1202, Houston, TX 77030, USA
    J Clin Oncol 26:791-7. 2008
    ..To review the state of the science with respect to diagnostic imaging and locoregional therapy for patients with breast cancer receiving preoperative chemotherapy...
  17. ncbi A phase I dose escalation trial of gemcitabine with radiotherapy for breast cancer in the treatment of unresectable chest wall recurrences
    W Warren Suh
    Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Breast J 10:204-10. 2004
    ..This novel approach suggests excellent local-regional control when compared to historical controls. A phase II trial is warranted...
  18. ncbi Unacceptable cosmesis in a protocol investigating intensity-modulated radiotherapy with active breathing control for accelerated partial-breast irradiation
    Reshma Jagsi
    Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109 5010, USA
    Int J Radiat Oncol Biol Phys 76:71-8. 2010
    ..To report interim cosmetic results and toxicity from a prospective study evaluating accelerated partial-breast irradiation (APBI) administered using a highly conformal external beam approach...
  19. ncbi Recurrent cancer after breast-conserving surgery with radiation therapy for ductal carcinoma in situ: mammographic features, method of detection, and stage of recurrence
    Renee W Pinsky
    Department of Radiology, University of Michigan Health System, 1500 E Medical Center Dr, Ann Arbor, MI 48109 0302, USA
    AJR Am J Roentgenol 189:140-4. 2007
    ....
  20. ncbi Rates of myocardial infarction and coronary artery disease and risk factors in patients treated with radiation therapy for early-stage breast cancer
    Reshma Jagsi
    Radiation Oncology Department, University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA
    Cancer 109:650-7. 2007
    ..Radiation therapy (RT), a critical component of breast-conserving therapy for breast cancer, has been associated with coronary artery disease (CAD) in numerous older studies, but the risk may be lower with modern techniques...
  21. ncbi Neoadjuvant docetaxel and capecitabine and the use of thymidine phosphorylase as a predictive biomarker in breast cancer
    Rachel M Layman
    Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109 0848, USA
    Clin Cancer Res 13:4092-7. 2007
    ..We evaluated whether TP protein expression is increased by docetaxel and correlates with pathologic complete response (pCR) in breast cancer patients...
  22. ncbi Sentinel node biopsy prior to neoadjuvant chemotherapy
    Michael S Sabel
    Breast Oncology Program and Division of Surgical Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA
    Am J Surg 186:102-5. 2003
    ..Sentinel lymph node biopsy prior to induction chemotherapy may address both...
  23. ncbi Assessment of skin dose for breast chest wall radiotherapy as a function of bolus material
    Shu Hui Hsu
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
    Phys Med Biol 53:2593-606. 2008
    ..The dosimetric effect of different Aquaplast materials has been quantified in this work. These materials can be used to create a custom bolus with potentially better reproducibility of placement...
  24. ncbi Dosimetry around metallic ports in tissue expanders in patients receiving postmastectomy radiation therapy: an ex vivo evaluation
    Janaki Moni
    Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA
    Med Dosim 29:49-54. 2004
    ..Strategies designed to reduce the breast reconstruction complication rate in this clinical setting will need to focus on factors other than adjusting the dosimetry around the tissue expander metallic port...
  25. ncbi Is lobular carcinoma in situ as a component of breast carcinoma a risk factor for local failure after breast-conserving therapy? Results of a matched pair analysis
    Merav A Ben-David
    Department of Radiation Oncology, Cancer and Geriatrics Center, University of Michigan Medical School, Ann Arbor, Michigan 48109 0010, USA
    Cancer 106:28-34. 2006
    ....
  26. ncbi Clinical and radiologic assessments to predict breast cancer pathologic complete response to neoadjuvant chemotherapy
    Anne F Schott
    Hematology Oncology Division, Department of Internal Medicine, University of Michigan, MI 48109 0848, USA
    Breast Cancer Res Treat 92:231-8. 2005
    ....
  27. ncbi Assessing the benefit of radiation therapy after breast-conserving surgery for ductal carcinoma-in-situ
    James A Hayman
    Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI 48109 0010, USA
    J Clin Oncol 23:5171-7. 2005
    ..To assess women's preferences regarding the trade-off between the risks and benefits of treatment with radiation therapy (RT) after breast-conserving surgery (BCS) for ductal carcinoma-in-situ (DCIS)...
  28. ncbi Potential gains for irradiation of chest wall and regional nodes with intensity modulated radiotherapy
    Editha A Krueger
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA
    Int J Radiat Oncol Biol Phys 56:1023-37. 2003
    ..To develop an intensity modulated radiotherapy (IMRT) technique for postmastectomy RT that improves target coverage while sparing all appropriate normal tissues...
  29. ncbi Accelerated partial breast irradiation: what is dosimetric effect of advanced technology approaches?
    Jean M Moran
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 75:294-301. 2009
    ..g., free breathing [FB] and deep inspiration breath hold [DIBH])...
  30. ncbi Status of postmastectomy radiotherapy in the United States: a patterns of care study
    Julia White
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Int J Radiat Oncol Biol Phys 60:77-85. 2004
    ..The Patterns of Care Study performed this first known practice survey to establish a national profile of the delivery of postmastectomy radiotherapy (RT) in operable breast cancer...
  31. ncbi Development and validation of a heart atlas to study cardiac exposure to radiation following treatment for breast cancer
    Mary Feng
    Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
    Int J Radiat Oncol Biol Phys 79:10-8. 2011
    ..Here we have developed a heart atlas and evaluated its effect on contour accuracy and concordance...
  32. ncbi Evaluation of four techniques using intensity-modulated radiation therapy for comprehensive locoregional irradiation of breast cancer
    Reshma Jagsi
    Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Int J Radiat Oncol Biol Phys 78:1594-603. 2010
    ..To establish optimal intensity-modulated radiation therapy (IMRT) techniques for treating the left breast and regional nodes, using moderate deep-inspiration breath hold...
  33. ncbi Short-term displacement and reproducibility of the breast and nodal targets under active breathing control
    Jean M Moran
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 68:541-6. 2007
    ....
  34. ncbi Conservative management of Paget disease of the breast with radiotherapy: 10- and 15-year results
    Jennifer K Marshall
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA
    Cancer 97:2142-9. 2003
    ....
  35. ncbi Clinical aspects of intensity-modulated radiotherapy in the treatment of breast cancer
    Editha A Krueger
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
    Semin Radiat Oncol 12:250-9. 2002
    ..Furthermore, IMRT may be able to reduce doses delivered to the heart and lungs, and may potentially minimize further the probability of complications from radiotherapy...
  36. ncbi Respiratory motion of the heart and positional reproducibility under active breathing control
    Reshma Jagsi
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
    Int J Radiat Oncol Biol Phys 68:253-8. 2007
    ..Information about cardiac motion with respiration and positional reproducibility under active breathing control (ABC) is necessary to evaluate these techniques...
  37. ncbi Cost-effectiveness of radiation therapy following conservative surgery for ductal carcinoma in situ of the breast
    W Warren Suh
    Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI, USA
    Int J Radiat Oncol Biol Phys 61:1054-61. 2005
    ..To assess the cost-effectiveness of radiation therapy (RT) in patients with ductal carcinoma in situ (DCIS) after breast-conserving surgery (BCS)...
  38. ncbi Cardiac chamber and coronary artery doses associated with postmastectomy radiotherapy techniques to the chest wall and regional nodes
    Editha A Krueger
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    Int J Radiat Oncol Biol Phys 60:1195-203. 2004
    ....
  39. ncbi Salvage treatment for local or local-regional recurrence after initial breast conservation treatment with radiation for ductal carcinoma in situ
    Lawrence J Solin
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Eur J Cancer 41:1715-23. 2005
    ..Close follow-up after initial breast conservation treatment with radiation is warranted for the early detection of potentially salvageable local and local-regional recurrences...
  40. ncbi Planning the breast tumor bed boost: changes in the excision cavity volume and surgical scar location after breast-conserving surgery and whole-breast irradiation
    Kevin S Oh
    Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Int J Radiat Oncol Biol Phys 66:680-6. 2006
    ..01). CONCLUSIONS: This study demonstrates a significant reduction in the volume of the excision cavity during whole-breast irradiation. Scar-guided boost plans provide inadequate coverage of the excision cavity in the majority of cases...
  41. ncbi Changes in surgical management resulting from case review at a breast cancer multidisciplinary tumor board
    Erika A Newman
    Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48109, USA
    Cancer 107:2346-51. 2006
    ..Multidisciplinary review can provide patients with useful additional information when making difficult treatment decisions...
  42. ncbi Treatment choices and response rates in African-American women with breast carcinoma
    Lisa A Newman
    Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, USA
    Cancer 97:246-52. 2003
    ....
  43. ncbi A cost comparison analysis of partial versus whole-breast irradiation after breast-conserving surgery for early-stage breast cancer
    W Warren Suh
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
    Int J Radiat Oncol Biol Phys 62:790-6. 2005
    ..To assess, if and for whom, there are cost savings associated with alternate breast radiotherapy (RT) techniques when compared with the conventional external beam-based whole-breast RT with a boost (WBRT-B)...
  44. ncbi Mammographic screening of TRAM flap breast reconstructions for detection of nonpalpable recurrent cancer
    Mark A Helvie
    Department of Radiology, University of Michigan Health System, 1500 E Medical Center Dr, Taubman Center 2910N, Ann Arbor, MI 48109-0326, USA
    Radiology 224:211-6. 2002
    ..A biopsy positive predictive value of 33% (95% CI: 6%, 76%) was observed. CONCLUSION: Screening mammography of TRAM flap-reconstructed breasts enables detection of nonpalpable cancer before clinical examination...
  45. ncbi Radiotherapy using a water bath in the treatment of Bowen's disease of the digit
    Joseph M Herman
    Department of Radiation Oncology, University of Michigan, Ann Arbor, USA
    Radiother Oncol 88:398-402. 2008
    ..Surgical treatment of BD of the digit can result in poor function and sometimes amputation. Here, we report our experience using a unique water bath technique to treat BD of the digit...
  46. ncbi Stroke rates and risk factors in patients treated with radiation therapy for early-stage breast cancer
    Reshma Jagsi
    Radiation Oncology Department, University of Michigan Cancer Center Biostatistics Core, and the University of Michigan School of Medicine, Ann Arbor, MI 48109-0010, USA
    J Clin Oncol 24:2779-85. 2006
    ..This study found no significant association between supraclavicular RT and stroke after controlling for other factors...
  47. ncbi Breast cancer
    Robert W Carlson
    Stanford Hospital and Clinics, USA
    J Natl Compr Canc Netw 3:238-89. 2005
  48. ncbi NCCN Task Force Report: breast cancer in the older woman
    Robert W Carlson
    J Natl Compr Canc Netw 6:S1-S25; quiz S26-S27. 2008
    ....
  49. ncbi A clinical trial of breast radiation therapy versus breast plus regional radiation therapy in early-stage breast cancer: the MA20 trial
    Ivo A Olivotto
    Radiation Oncology, British Columbia Cancer Agency and University of British Columbia, Vancouver Island Centre, 2410 Lee Avenue, Victoria, BC V8R 6V5, Canada
    Clin Breast Cancer 4:361-3. 2003
  50. ncbi Invasive breast cancer
    Robert W Carlson
    National Comprehensive Cancer Network
    J Natl Compr Canc Netw 5:246-312. 2007
  51. ncbi Sequencing of tamoxifen and radiotherapy after breast-conserving surgery in early-stage breast cancer
    Lori J Pierce
    Southwest Oncology Group, San Antonio, TX, USA
    J Clin Oncol 23:24-9. 2005
    ..04; P = .54). CONCLUSION: The current analysis does not suggest an adverse effect on local or systemic control with CONC versus SEQ TAM and RT in node-negative breast cancer. A randomized trial is encouraged to validate these results...
  52. ncbi An academic health center cost analysis of screening mammography: creating a financially viable service
    Steven L Chen
    University of Michigan Center for Health Care Economics, Ann Arbor 48109, USA
    Cancer 101:1043-50. 2004
    ..Based on favorable contribution margins, SM programs were viable when viewed as incremental business...

Research Grants4

  1. IMRT in the Treatment of Node-Positive Breast Cancer
    Lori Pierce; Fiscal Year: 2003
    ..4) Determine the effect of motion on static IMRT and PWTF dose distributions, and then correct/adjust for motion to determine the best delivery-optimized plan. ..
  2. IMRT in the Treatment of Node-Positive Breast Cancer
    Lori Pierce; Fiscal Year: 2006
    ..3) Study 60 patients treated with either the best delivery-optimized motion corrected plan from Aim 2 or PWTF and compare plans using heart and lung metrics. ..