Research Topics
| Karen PierceSummaryAffiliation: University of California Country: USA Publications
|
Detail Information
Publications
Mapping early brain development in autismEric Courchesne
Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA
Neuron 56:399-413. 2007..As such, autism may additionally provide unique insight into genetic and developmental processes that shape early neural wiring patterns and make possible higher-order social, emotional, and communication functions...- The brain response to personally familiar faces in autism: findings of fusiform activity and beyondKaren Pierce
Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA
Brain 127:2703-16. 2004..Therefore, dysfunction in the FFA found in other studies of autism may reflect defects in systems that modulate the FFA, rather than the FFA itself... - Abnormal variability and distribution of functional maps in autism: an FMRI study of visuomotor learningRalph Axel Müller
Department of Psychology, San Diego State University, Childrens Hospital Reserch Children, La Jolla, California 92120, USA
Am J Psychiatry 160:1847-62. 2003..The authors examined whether such abnormalities generalize to multimodal processing (visually driven motor sequence learning)... 
Disrupted neural synchronization in toddlers with autismILAN DINSTEIN
Autism Center of Excellence, University of California San Diego, La Jolla, CA 92037, USA
Neuron 70:1218-25. 2011..Disrupted cortical synchronization, therefore, appears to be a notable characteristic of autism neurophysiology that is evident at very early stages of autism development...- Detecting, studying, and treating autism early: the one-year well-baby check-up approachKaren Pierce
Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, CA 92037, USA
J Pediatr 159:458-465.e1-6. 2011..To determine the feasibility of implementing a broadband screen at the 1-year check-up to detect cases of autism spectrum disorders (ASD), language delay (LD), and developmental delay (DD)... 
Neuron number and size in prefrontal cortex of children with autismEric Courchesne
Department of Neuroscience, NIH UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA
JAMA 306:2001-10. 2011..Autism often involves early brain overgrowth, including the prefrontal cortex (PFC). Although prefrontal abnormality has been theorized to underlie some autistic symptoms, the cellular defects that cause abnormal overgrowth remain unknown...- Fusiform function in children with an autism spectrum disorder is a matter of "who"Karen Pierce
Department of Neuroscience, University of California, San Diego, USA
Biol Psychiatry 64:552-60. 2008..To fill this gap, 45 children aged 6-12 participated in practice scans. After exclusion due to motion, 11 children with an ASD and 11 age-matched normal control subjects were included in final analyses... - A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autismLisa T Eyler
UCSD Autism Center of Excellence, University of California, San Diego, La Jolla, CA 92037, USA
Brain 135:949-60. 2012.... - Longitudinal magnetic resonance imaging study of cortical development through early childhood in autismCynthia M Schumann
Autism Center of Excellence, Department of Neurosciences, Center for Human Development, and Departments of Psychiatry and Radiology, University of California, San Diego, La Jolla, California 92093, USA
J Neurosci 30:4419-27. 2010.... - Brain overgrowth in autism during a critical time in development: implications for frontal pyramidal neuron and interneuron development and connectivityEric Courchesne
Department of Neurosciences, University of California, San Diego, CA, USA
Int J Dev Neurosci 23:153-70. 2005..The relationship to clinical characteristics and other disorders of macrencephaly are discussed... - Preference for geometric patterns early in life as a risk factor for autismKaren Pierce
Department of Neurosciences, Autism Center of Excellence, University of California, San Diego, La Jolla, 92037, USA
Arch Gen Psychiatry 68:101-9. 2011..The extent to which a preference for looking at geometric repetition is an early risk factor for autism has yet to be examined... - Early functional brain development in autism and the promise of sleep fMRIKaren Pierce
Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, CA, USA
Brain Res 1380:162-74. 2011..The ability to do so relies on improving and streamlining early identification and thus early treatment efforts... - Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnectionEric Courchesne
Department of Neurosciences, University of California, San Diego, CA, USA
Curr Opin Neurobiol 15:225-30. 2005.... - The neurobiological basis of autism from a developmental perspectiveNatacha Akshoomoff
Laboratory for Research on the Neuroscience of Autism, Children s Hospital Research Center, La Jolla, CA 92037, USA
Dev Psychopathol 14:613-34. 2002..We discuss how these recent advances have led us to develop a growth dysregulation hypothesis of autism. Finally, we discuss how this hypothesis may lead to new innovations in autism research... - The power and promise of identifying autism early: insights from the search for clinical and biological markersKaren Pierce
Department of Neurosciences, University of California, San Diego, San Diego, CA 92037, USA
Ann Clin Psychiatry 21:132-47. 2009..The study of the biological basis of autism prior to age 3 is essential and can most directly be achieved with prospective research designs... - Functional MRI of motor sequence acquisition: effects of learning stage and performanceRalph Axel Müller
Department of Psychology, San Diego State University, MC1863, 6363 Alvarado Ct 200, San Diego, CA 92120, USA
Brain Res Cogn Brain Res 14:277-93. 2002....