Research Topics
| Perry J PickhardtSummaryAffiliation: University of Wisconsin Country: USA Publications
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Publications
Computed tomography colonography: emerging evidence to further support clinical effectivenessPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 3252, USA
Curr Opin Gastroenterol 29:55-9. 2013..The aim of this review is to provide an update on the recent and emerging data that further supports the clinical effectiveness of CTC...
Missed lesions at CT colonography: lessons learnedPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Abdom Imaging 38:82-97. 2013....
Abdominal CT with model-based iterative reconstruction (MBIR): initial results of a prospective trial comparing ultralow-dose with standard-dose imagingPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 199:1266-74. 2012..The purpose of this study was to report preliminary results of an ongoing prospective trial of ultralow-dose abdominal MDCT...
CT colonography: pitfalls in interpretationPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 3252, USA
Radiol Clin North Am 51:69-88. 2013..Tips and pointers for how to effectively handle these potential pitfalls are included...
Visceral adiposity and hepatic steatosis at abdominal CT: association with the metabolic syndromePerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, 53792 3252, USA
AJR Am J Roentgenol 198:1100-7. 2012..Visceral adiposity and hepatic steatosis may correlate with the metabolic syndrome but are not currently among the diagnostic criteria. We evaluated these features at unenhanced MDCT...
Randomized controlled trial evaluating participation and yield of colonoscopy versus CT colonography screeningPerry J Pickhardt
Gastrointestinal Imaging, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3252, USA
Expert Rev Med Devices 9:107-10. 2012..The landmark trial under discussion adds key data in terms of participation rates for CTC screening relative to colonoscopy screening...
CT colonography to screen for colorectal cancer and aortic aneurysm in the Medicare population: cost-effectiveness analysisPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 192:1332-40. 2009..CTC can also accurately detect abdominal aortic aneurysm (AAA). This collaborative gastroenterology-radiology project evaluated the cost-effectiveness and clinical efficacy of CTC in the Medicare population...
Positive predictive value for polyps detected at screening CT colonographyPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 3252, USA
Eur Radiol 20:1651-6. 2010..To determine the positive predictive value (PPV) for polyps detected at CT colonography (CTC)...
Clinical management of small (6- to 9-mm) polyps detected at screening CT colonography: a cost-effectiveness analysisPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 191:1509-16. 2008..The primary aim of this model analysis was to compare the clinical and economic impacts of immediate polypectomy versus 3-year CT colonography (CTC) surveillance for small (6- to 9-mm) polyps detected at CTC screening...
Unsuspected extracolonic findings at screening CT colonography: clinical and economic impactPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 249:151-9. 2008..To evaluate the frequency and estimated costs of additional diagnostic workup for extracolonic findings detected at computed tomographic (CT) colonography in a large screening cohort...
Low rates of cancer or high-grade dysplasia in colorectal polyps collected from computed tomography colonography screeningPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 3252, USA
Clin Gastroenterol Hepatol 8:610-5. 2010..We assess the rates of cancer and high-grade dysplasia among patients found to have small (6-9 mm) and large (>or=10 mm) colorectal polyps at CTC...
Polyp detection at 3-dimensional endoluminal computed tomography colonography: sensitivity of one-way fly-through at 120 degrees field-of-view anglePerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 3252, USA
J Comput Assist Tomogr 33:631-5. 2009....
Incidental adnexal masses detected at low-dose unenhanced CT in asymptomatic women age 50 and older: implications for clinical management and ovarian cancer screeningPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, Madison, WI 53792 3252, USA
Radiology 257:144-50. 2010..To determine the prevalence, work-up, and outcomes of indeterminate adnexal masses identified at low-dose unenhanced computed tomography (CT) in asymptomatic women age 50 and older undergoing colonography screening...
Left-sided polyps detected at screening CT colonography: do we need complete optical colonoscopy for further evaluation?Perry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 259:429-34. 2011..To estimate the relative yield of therapeutic flexible sigmoidoscopy compared with complete optical colonoscopy for isolated left-sided polyps (≥6 mm in diameter) identified at screening computed tomographic (CT) colonography...
Colorectal cancer: CT colonography and colonoscopy for detection--systematic review and meta-analysisPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 259:393-405. 2011..To perform a systematic review and meta-analysis of published studies assessing the sensitivity of both computed tomographic (CT) colonography and optical colonoscopy (OC) for colorectal cancer detection...
Cost-effectiveness of colorectal cancer screening with computed tomography colonography: the impact of not reporting diminutive lesionsPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, Madison, Wisconsin 53792 3252, USA
Cancer 109:2213-21. 2007..The purpose of the current study was to assess the potential harms, benefits, and cost-effectiveness of CTC screening without the reporting of diminutive lesions compared with other screening strategies...
Diagnostic performance of multidetector computed tomography for suspected acute appendicitisPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 3252, USA
Ann Intern Med 154:789-96, W-291. 2011..Use of preoperative computed tomography for suspected acute appendicitis has dramatically increased since the introduction of multidetector CT (MDCT) scanners...
Simultaneous screening for osteoporosis at CT colonography: bone mineral density assessment using MDCT attenuation techniques compared with the DXA reference standardPerry J Pickhardt
University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 3252, USA
J Bone Miner Res 26:2194-203. 2011..It is concluded that both phantomless QCT and simple ROI attenuation measurements of the lumbar spine are effective for BMD screening at CTC with high sensitivity for osteoporosis, as defined by the DXA T-score...
Noninvasive radiologic imaging of the large intestine: a valuable complement to optical colonoscopyPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 3252, USA
Curr Opin Gastroenterol 26:61-8. 2010..The aim of this review is to provide an update on current and emerging clinical capabilities for a variety of radiologic diagnostic imaging tools for evaluating the colon and rectum...
Should small sliding hiatal hernias be reported at CT colonography?Perry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 196:W400-4. 2011..The objective of our study was to determine whether colonic distention at CT colonography (CTC) induces small incidental sliding hiatal hernias...
Small and diminutive polyps detected at screening CT colonography: a decision analysis for referral to colonoscopyPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 190:136-44. 2008..The objective of this study was to assess the clinical and economic impact of colonoscopic referral for small and diminutive polyps detected at CT colonography (CTC) screening...
CT colonography versus colonoscopy for the detection of advanced neoplasiaDavid H Kim
Department of Radiology, University of Wisconsin Medical School, Madison 53792 3252, USA
N Engl J Med 357:1403-12. 2007..Advanced neoplasia represents the primary target for colorectal-cancer screening and prevention. We compared the diagnostic yield from parallel computed tomographic colonography (CTC) and optical colonoscopy (OC) screening programs...
Hepatic steatosis (fatty liver disease) in asymptomatic adults identified by unenhanced low-dose CTCody J Boyce
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 194:623-8. 2010..S. adult population using attenuation values at unenhanced CT as the reference standard. We also assessed the utility of known clinical risk factors for diagnosis...
Accuracy of routine nontargeted CT without colonography technique for the detection of large colorectal polyps and cancerBora Ozel
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 3252, USA
Dis Colon Rectum 53:911-8. 2010..To assess the accuracy of routine contrast-enhanced computed tomography for the detection of large colorectal polyps and cancer...
Evaluation of submucosal lesions of the large intestine: part 2. Nonneoplastic causesPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, 600 Highland Ave, E3 311 Clinical Science Center, Madison, WI 53792 3252, USA
Radiographics 27:1693-703. 2007....
Primary 2D versus primary 3D polyp detection at screening CT colonographyPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 189:1451-6. 2007..Our goal was to assess the sensitivity of primary 2D polyp detection with cases from the Department of Defense CTC screening trial and compare results with the primary 3D evaluation and previous 2D CTC trials...
Five year colorectal cancer outcomes in a large negative CT colonography screening cohortDavid H Kim
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Eur Radiol 22:1488-94. 2012..To assess the 5-year incidence of clinically presenting colorectal cancers following a negative CT colonography (CTC) screening examination, as few patient outcome data regarding a negative CTC screening result exist...
Low-volume hybrid bowel preparation combining saline laxatives with oral contrast agents versus standard polyethylene glycol lavage for colonoscopyEdward M Lawrence
University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 3252, USA
Dis Colon Rectum 53:1176-81. 2010..The aim of this study was to compare the quality of low-volume hybrid computed tomography colonography bowel preparation, using both laxatives and oral contrast, with standard polyethylene glycol lavage...
Screening CT colonography: how I do itPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 189:290-8. 2007..CT colonography is ideally suited for widespread screening of asymptomatic adults and has become an integral component of the screening efforts at my institution since local third-party coverage was initiated...
CT colonography: performance and program outcome measures in an older screening populationDavid H Kim
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 254:493-500. 2010..To evaluate computed tomographic (CT) colonography performance and program outcome measures in an older cohort (65-79 years) of an established large-scale colorectal cancer screening program...
Findings on optical colonoscopy after positive CT colonography examDaniel Cornett
Section of Gastroenterology and Hepatology, Department of Medicine, University of Wisconsin Madison School of Medicine and Public Health, Madison, Wisconsin 53792 5124, USA
Am J Gastroenterol 103:2068-74. 2008..The aim of this study is to evaluate the findings on optical colonoscopy (OC) after a positive CT colonography (CTC) exam and characterize the type of polyps seen on OC but not reported by CTC...
Is there sufficient MDCT capacity to provide colorectal cancer screening with CT colonography for the U.S. population?Perry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 190:1044-9. 2008..Our aim was to assess the ability of the available MDCT capacity in the United States to provide population screening with CTC...
Reproducibility of tumor volume measurement at microCT colonography in living miceBenjamin Y Durkee
Department of Medical Physics, 1400 University Avenue, University of Wisconsin, Madison, WI 53706, USA
Acad Radiol 15:334-41. 2008..The precision and accuracy of volumetric measurements were determined to assess whether changes in tumor volume over time were readily detectable...
Flat colorectal lesions in asymptomatic adults: implications for screening with CT virtual colonoscopyPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, Madison, 600 Highland Ave, E3/311 Clinical Science Center, Madison, WI 53792-3252, USA
AJR Am J Roentgenol 183:1343-7. 2004..The sensitivity of virtual colonoscopy for detecting flat lesions was similar to that of polypoid lesions. These results indicate that flat lesions are not a significant drawback for virtual colonoscopy screening...
Colorectal polyps: stand-alone performance of computer-aided detection in a large asymptomatic screening populationEdward M Lawrence
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, Madison, WI 53792 3252, USA
Radiology 256:791-8. 2010..To evaluate stand-alone performance of computer-aided detection (CAD) for colorectal polyps of 6 mm or larger at computed tomographic (CT) colonography in a large asymptomatic screening cohort...
Performing an additional decubitus series at CT colonographyChristopher M Buchach
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Clinical Science Center, Madison, 53792 3252, USA
Abdom Imaging 36:538-44. 2011..To determine the rate and associated factors for acquiring a decubitus series at CT colonography (CTC), in addition to the standard supine and prone series...
Location of adenomas missed by optical colonoscopyPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3252, USA
Ann Intern Med 141:352-9. 2004..Previous estimates of the adenoma miss rate with optical colonoscopy (OC) are hindered by the use of OC as its own reference standard...
Imaging evaluation of complications at optical colonoscopyDavid H Kim
Department of Radiology, University of Wisconsin Medical School, Madison, WI 53792 3252, USA
Curr Probl Diagn Radiol 37:165-77. 2008..Emphasis will be placed on cross-sectional imaging given the improved sensitivity and specificity over conventional radiography...
Surface visualization at 3D endoluminal CT colonography: degree of coverage and implications for polyp detectionPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, Madison, Wisconsin, USA
Gastroenterology 130:1582-7. 2006....
Screening for colorectal neoplasia with CT colonography: initial experience from the 1st year of coverage by third-party payersPerry J Pickhardt
Department of Radiology and Section of Gastroenterology and Hepatology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 241:417-25. 2006..To evaluate our experience in the 1st year of computed tomographic (CT) colonography screening since the initiation of local third-party payer coverage...
Prevalence of urolithiasis in asymptomatic adults: objective determination using low dose noncontrast computerized tomographyCody J Boyce
University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 3252, USA
J Urol 183:1017-21. 2010..Unenhanced computerized tomography represents the gold standard for detection. We evaluated the prevalence and symptomatic incidence of urolithiasis in a large cohort of asymptomatic adults using noncontrast computerized tomography...
Colorectal and extracolonic cancers detected at screening CT colonography in 10,286 asymptomatic adultsPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 255:83-8. 2010....
Impact of a CT colonography screening program on endoscopic colonoscopy in clinical practiceDarren C Schwartz
Department of Medicine, Section of Gastroenterology and Hepatology, University of Wisconsin Medical School Madison, Madison, WI 53792 5124, USA
Am J Gastroenterol 103:346-51. 2008..The potential effect of CT colonography (CTC) on endoscopic colonoscopy (EC) has been the topic of much speculation. The aim of this study was to evaluate the impact of a CTC screening program on colonoscopy in clinical practice...
Asymptomatic pneumatosis at CT colonography: a benign self-limited imaging finding distinct from perforationPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 190:W112-7. 2008..The purpose of our study was to report the prevalence and clinical course of colonic pneumatosis at CT colonography (CTC)...
CT colonography with computer-aided polyp detection: volume and attenuation thresholds to reduce false-positive findings owing to the ileocecal valveRonald M Summers
Department of Radiology, National Institutes of Health, 10 Center Dr, Bldg 10, Rm 1C351, MSC 1182, Bethesda, MD 20892-1182, USA
Radiology 241:426-32. 2006..Differences in sensitivity and specificity in the detection of polyps between the sets were not significant. CONCLUSION: Volume and average CT attenuation thresholds can help differentiate most ICVs from true polyps...
Venous malformations mimicking multiple mucosal polyps on screening CT colonographyAndrew D Lee
Department of Radiology, University of Wisconsin Medical School, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252, USA
AJR Am J Roentgenol 186:1113-5. 2006
Reduced image noise at low-dose multidetector CT of the abdomen with prior image constrained compressed sensing algorithmMeghan G Lubner
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 31 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 260:248-56. 2011..To assess the effect of prior image constrained compressed sensing (PICCS) on noise reduction and image quality at low-dose computed tomography (CT)...
Bowel preparation for CT colonography: blinded comparison of magnesium citrate and sodium phosphate for catharsisZachary S Borden
Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, G3 310 CSC MC 3252, Madison, WI 53792 3252, USA
Radiology 254:138-44. 2010..To compare colonic cleansing and fluid retention of double-dose magnesium citrate with those of single-dose sodium phosphate in patients undergoing computed tomographic (CT) colonography...
Renal cell carcinoma: attenuation values on unenhanced CTB Dustin Pooler
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, 53792 3252, USA
AJR Am J Roentgenol 198:1115-20. 2012..The purpose of this study is to analyze the attenuation values of pathologically proven renal cell carcinomas (RCCs) on unenhanced CT and to determine the range of values wherein malignancy should be considered...
Primary neoplasms of the appendix manifesting as acute appendicitis: CT findings with pathologic comparisonPerry J Pickhardt
Department of Radiology, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889 5600, USA
Radiology 224:775-81. 2002..To evaluate the computed tomographic (CT) findings in patients with acute appendicitis related to an underlying appendiceal neoplasm...
Prospective blinded comparison of polyp size on computed tomography colonography and endoscopic colonoscopyCourtney Barancin
Section of Gastroenterology and Hepatology, Department of Medicine, University of Wisconsin Madison School of Medicine and Public Health, Madison, Wisconsin 53792, USA
Clin Gastroenterol Hepatol 9:443-5. 2011..We compared polyp size as seen on CTC with endoscopic visualization, in vivo probe measurement, and ex vivo size before and after fixation...
Characteristics of advanced adenomas detected at CT colonographic screening: implications for appropriate polyp size thresholds for polypectomy versus surveillanceDavid H Kim
Department of Radiology, University of Wisconsin Medical School, 600 Highland Ave, E3 311 Clinical Science Center, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 188:940-4. 2007..These observations may be a basis for formulation of polypectomy thresholds and CTC surveillance strategies...
Increasing computer-aided detection specificity by projection features for CT colonographyHongbin Zhu
Department of Radiology, State University of New York, Stony Brook, New York 11794, USA
Med Phys 37:1468-81. 2010..This study aims to develop projection-based features which characterize true and false positives to increase the specificity while maintaining high sensitivity in detecting colonic polyps...
Evaluation of submucosal lesions of the large intestine: part 1. NeoplasmsPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, 600 Highland Ave, E3 311 Clinical Science Center, Madison, WI 53792 3252, USA
Radiographics 27:1681-92. 2007..It is important that radiologists be familiar with the multimodality imaging appearances of such entities so that neoplasms--especially those that are malignant--can be accurately identified and characterized and effectively managed...
Diagnostic performance of primary 3-dimensional computed tomography colonography in the setting of colonic diverticular diseaseMatthew F Sanford
Department of Radiology, University of Wisconsin Medical School, Madison, 53792, USA
Clin Gastroenterol Hepatol 4:1039-47. 2006..7% (61/72), respectively (not significant, P > or = .15). CONCLUSIONS: CDD was common in this asymptomatic screening population, but its presence did not degrade the diagnostic performance of primary 3D CTC for polyp detection...
Automated seed placement for colon segmentation in computed tomography colonographyGheorghe Iordanescu
Department of Radiology, National Institutes of Health, Building 10, Room 1C660, 10 Center Drive MSC 1182, Bethesda, MD 20892-1182, USA
Acad Radiol 12:182-90. 2005..CONCLUSION: Fully automatic seed placement for colonic segmentation is feasible in the majority of cases without seeding of undesired extracolonic air...
The effect of diagnostic confidence on the probability of optical colonoscopic confirmation of potential polyps detected on CT colonography: prospective assessment in 1,339 asymptomatic adultsPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252, USA
AJR Am J Roentgenol 183:1661-5. 2004..Although polyp size represents the primary criterion for CTC screening algorithms, this data could help guide the decision to opt for noninvasive CTC surveillance versus optical colonoscopy for polypectomy...
Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adultsPerry J Pickhardt
Department of Radiology, National Naval Medical Center, Bethesda, MD, USA
N Engl J Med 349:2191-200. 2003..We evaluated the performance characteristics of computed tomographic (CT) virtual colonoscopy for the detection of colorectal neoplasia in an average-risk screening population...
CT colonography (virtual colonoscopy): a practical approach for population screeningPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiol Clin North Am 45:361-75. 2007..It discusses the entire spectrum from program set-up through patient disposition following CTC examination. The authors hope this article will provide a roadmap for radiologists who wish to institute a CTC screening program...
Anatomic factors predictive of incomplete colonoscopy based on findings at CT colonographyMeghan E Hanson
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 189:774-9. 2007..Reasons for failure to reach the cecum at optical colonoscopy are multifactorial. The purpose of this study was to compare CT colonography (CTC) findings in patients with complete versus those with incomplete optical colonoscopy...
Primary neoplasms of the appendix: radiologic spectrum of disease with pathologic correlationPerry J Pickhardt
Department of Radiology, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889 5600, USA
Radiographics 23:645-62. 2003..CT appears to be the modality of choice whenever an appendiceal mass is suspected. CT will help rule out or confirm an appendiceal tumor and may suggest a more specific diagnosis...
Incidental finding of renal masses at unenhanced CT: prevalence and analysis of features for guiding managementStacy D O'Connor
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, 53792 3252, USA
AJR Am J Roentgenol 197:139-45. 2011..The purposes of this study were to investigate the frequency and clinical relevance of the incidental finding of renal masses at low-dose unenhanced CT and to analyze the results for features that can be used to guide evaluation...
Polyp volume versus linear size measurements at CT colonography: implications for noninvasive surveillance of unresected colorectal lesionsPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, 600 Highland Ave, Madison, WI 53792, USA
AJR Am J Roentgenol 186:1605-10. 2006..CONCLUSION: Because changes in polyp volume are amplified compared with linear dimension, volume measurement rather than diameter measurement will better allow detection of small incremental changes in polyp size using CTC...
Performance of CT colonography for detecting small, diminutive, and flat polypsPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3252, USA
Gastrointest Endosc Clin N Am 20:209-26. 2010..However, the actual clinical relevance of small, diminutive, and flat polyps has also been the source of debate. This article addresses these controversial and often misunderstood issues...
Extracolonic tumors of the gastrointestinal tract detected incidentally at screening CT colonographyPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, Wisconsin 53792 3252, USA
Dis Colon Rectum 50:56-63. 2007..The aim of this article is to report our experience with incidental detection of extracolonic tumors of the gastrointestinal tract identified prospectively at screening CT colonography...
Radiologists should read CT colonographyDavid H Kim
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 600 Highland Avenue, Madison, WI 53792 3252, USA
Gastrointest Endosc Clin N Am 20:259-69. 2010..The role of extracolonic evaluation as an integral part of this examination is also covered. Within this context, the question of whether a radiologist or gastroenterologist is better suited to interpret this examination is explored...
Three-dimensional endoluminal CT colonography (virtual colonoscopy): comparison of three commercially available systemsPerry J Pickhardt
Department of Radiology, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889-5600, USA
AJR Am J Roentgenol 181:1599-606. 2003..Of the three, effective time-efficient primary 3D evaluation appears to be feasible only with the V3D-Colon system...
Effect of colonic distention on superiority of supine versus prone views in screening computed tomographic colonographySteven J Michel
Department of Radiology, University of Wisconsin Medical School, Madison, WI, USA
Clin Imaging 31:325-8. 2007..The purpose of this study was to evaluate the effect of colonic distention in computed tomographic colonography (CTC)...
Inverted appendiceal stumps simulating large pedunculated polyps on screening CT colonographyTyler M Prout
Department of Radiology, University of Wisconsin Medical School, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252, USA
AJR Am J Roentgenol 186:535-8. 2006
CT-guided lung biopsies: pleural blood patching reduces the rate of chest tube placement for postbiopsy pneumothoraxJason M Wagner
Department of Radiology, University of Wisconsin, 600 Highland Ave, Mail Code 3252, E3 311 CSC, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 197:783-8. 2011..The objective of our study was to determine whether pleural blood patching reduces the need for chest tube placement and hospital admission for pneumothorax complicating CT-guided percutaneous lung biopsy...
Colorectal cancer: managing diminutive polyps-what is the optimal approach?David H Kim
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3252, USA
Nat Rev Gastroenterol Hepatol 8:129-31. 2011....
Prospective blinded trial comparing 45-mL and 90-mL doses of oral sodium phosphate for bowel preparation before computed tomographic colonographyDavid H Kim
Department of Radiology University of Wisconsin Medical School, Madison, WI 53792 3252, USA
J Comput Assist Tomogr 31:53-8. 2007..To compare the efficacy of computed tomographic colonography (CTC) bowel preparation using single- (45 mL) versus double-dose sodium phosphate...
Nonadenomatous polyps at CT colonography: prevalence, size distribution, and detection ratesPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 232:784-90. 2004..To prospectively investigate with computed tomographic (CT) colonography the prevalence and size distribution of nonadenomatous polyps in asymptomatic adults and to compare the detection rates of adenomatous and nonadenomatous polyps...
Flat (nonpolypoid) colorectal lesions identified at CT colonography in a U.S. screening populationPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3252, USA
Acad Radiol 17:784-90. 2010..The aim of this study was to investigate the clinical importance and height definition of flat (nonpolypoid) colorectal lesions detected on screening computed tomographic colonography (CTC)...
Colorectal cancer screening with CT colonography: key concepts regarding polyp prevalence, size, histology, morphology, and natural historyPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
AJR Am J Roentgenol 193:40-6. 2009..Familiarity with current concepts regarding flat (nonpolypoid) lesions and the natural history of small colorectal polyps is also vital to the effective application of this technique...
Imaging of primary malignant tumors of peritoneal and retroperitoneal originJ Louis Hinshaw
Department of Radiology, University of Wisconsin Medical School, Madison, WI, 53792, USA
Cancer Treat Res 143:281-97. 2008....
Linear polyp measurement at CT colonography: in vitro and in vivo comparison of two-dimensional and three-dimensional displaysPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 236:872-8. 2005....
Radiologic assessment of acute and chronic pancreatitisDavid H Kim
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3252, USA
Surg Clin North Am 87:1341-58, viii. 2007..CT remains a major focal point in issues related to acute pancreatitis, whereas MRI (and magnetic resonance cholangiopancreatography) plays a larger role in chronic pancreatitis...
Translucency rendering in 3D endoluminal CT colonography: a useful tool for increasing polyp specificity and decreasing interpretation timePerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, Clinical Science Center, 600 Highland Ave, E3/311, Madison, WI 53792-3252, USA
AJR Am J Roentgenol 183:429-36. 2004
Electronic cleansing and stool tagging in CT colonography: advantages and pitfalls with primary three-dimensional evaluationPerry J Pickhardt
Department of Radiology, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889-5600, USA
AJR Am J Roentgenol 181:799-805. 2003
Incidence of colonic perforation at CT colonography: review of existing data and implications for screening of asymptomatic adultsPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252, USA
Radiology 239:313-6. 2006
Adenomatous polyp obscured by small-caliber rectal catheter at low-dose CT colonography: a rare diagnostic pitfallPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252, USA
AJR Am J Roentgenol 184:1581-3. 2005
Virtual colonoscopy: issues related to primary screeningPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3252, USA
Eur Radiol 15:D133-7. 2005....
Differential diagnosis of polypoid lesions seen at CT colonography (virtual colonoscopy)Perry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792, USA
Radiographics 24:1535-56; discussion 1557-9. 2004..A variety of useful techniques and observations can be used to increase the specificity of CT colonography for distinguishing false polyps from true polyps...
The natural history of colorectal polyps and masses: rediscovered truths from the barium enema eraPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252, USA
AJR Am J Roentgenol 188:619-21. 2007
Intestinal malrotation in adolescents and adults: spectrum of clinical and imaging featuresPerry J Pickhardt
Department of Radiology, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889-5600, USA
AJR Am J Roentgenol 179:1429-35. 2002
Computerized tomography colonography: a primer for gastroenterologistsPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, Madison, Wisconsin 53792-3252, USA
Clin Gastroenterol Hepatol 6:497-502. 2008
CT colonography with computer-aided detection as a second reader: observer performance studyNicholas Petrick
National Institute of Biomedical Imaging and Bioengineering Center for Devices and Radiological Health Joint Laboratory for the Assessment of Medical Imaging Systems, U S Food and Drug Administration, Rockville, MD, USA
Radiology 246:148-56. 2008....
By-patient performance characteristics of CT colonography: importance of polyp size threshold dataPerry J Pickhardt
Radiology 229:291-3; author reply 293; discussion 293. 2003
Teniae coli-based circumferential localization system for CT colonography: feasibility studyAdam Huang
Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892 1182, USA
Radiology 243:551-60. 2007..The teniae coli are extractable landmarks, and the teniae coli-based circumferential localization system helps guide virtual navigation and polyp registration at CT colonography...
Computed tomographic virtual colonoscopy computer-aided polyp detection in a screening populationRonald M Summers
Diagnostic Radiology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1182, USA
Gastroenterology 129:1832-44. 2005..Our objective was to determine whether a computer program is as sensitive as optical colonoscopy for the detection of adenomatous colonic polyps on CT virtual colonoscopy...
Computed tomographic colonography to screen for colorectal cancer, extracolonic cancer, and aortic aneurysm: model simulation with cost-effectiveness analysisCesare Hassan
Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, and Department of Radiological Sciences, University Polo Pontino, Rome, Italy
Arch Intern Med 168:696-705. 2008..The efficacy and cost-effectiveness of this combined abdominal CT screening strategy are unknown...
Polyps: linear and volumetric measurement at CT colonographySrinath C Yeshwant
Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Bldg 10, Room 1C351, 10 Center Dr, MSC 1182, Bethesda, MD 20892-1182, USA
Radiology 241:802-11. 2006..Linear diameter calculated from automated volume measurements showed the smallest variation between supine and prone scans while avoiding observer variability and may be best for assessing polyp size changes with serial examinations...
Screening for nonpolypoid colorectal neoplasmsPerry J Pickhardt
JAMA 299:2743; author reply 2743-4. 2008
Performance of a previously validated CT colonography computer-aided detection system in a new patient populationRonald M Summers
Diagnostic Radiology Department, National Institutes of Health Clinical Center, Bldg 10, Rm 1C368X MSC 1182, Bethesda, MD 20892 1182, USA
AJR Am J Roentgenol 191:168-74. 2008....
Utilization of the double-contrast barium enema in the early era of screening CT colonographyPerry J Pickhardt
AJR Am J Roentgenol 187:W661. 2006
Revised colorectal screening guidelines: joint effort of the American Cancer Society, U.S. Multisociety Task Force on Colorectal Cancer, and American College of RadiologyElizabeth G McFarland
Radiology 248:717-20. 2008
The cost-effectiveness of CT colonography in screening for colorectal neoplasiaSandeep Vijan
Veterans Affairs Health Services Research and Development Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48105, USA
Am J Gastroenterol 102:380-90. 2007..We examined the cost-effectiveness of 2- and 3-dimensional computerized tomography (CT) colonography as a screening test for colorectal neoplasia...
Case report. CT, MR cholangiopancreatography, and endoscopy findings in Bouveret's syndromePerry J Pickhardt
Department of Radiology, , Uniformed Services University of the Health Sciences, Bethesda, MD, USA
AJR Am J Roentgenol 180:1033-5. 2003
Quality assessment for CT colonography: validation of automated measurement of colonic distention and residual fluidKeshav K Deshpande
Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Bldg 10, Room 1C368X, Bethesda, MD 20892 1182, USA
AJR Am J Roentgenol 189:1457-63. 2007....
Fitz-Hugh-Curtis syndrome: multidetector CT findings of transient hepatic attenuation difference and gallbladder wall thickeningPerry J Pickhardt
Department of Radiology, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889-5600, USA
AJR Am J Roentgenol 180:1605-6. 2003
