Research Topics
| Adam M PhillippySummaryAffiliation: University of Maryland Country: USA Publications
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Detail Information
Publications
Probing the pan-genome of Listeria monocytogenes: new insights into intraspecific niche expansion and genomic diversificationXiangyu Deng
National Center for Food Safety and Technology, Illinois Institute of Technology, Summit, Illinois 60501, USA
BMC Genomics 11:500. 2010..Two of these lineages predominantly cause human sporadic and epidemic infections, whereas the third lineage has never been implicated in human disease outbreaks despite its overall conservation of many known virulence factors...
Comprehensive DNA signature discovery and validationAdam M Phillippy
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America
PLoS Comput Biol 3:e98. 2007..The Insignia system is freely accessible via a Web interface and has been released as open source software at: http://insignia.cbcb.umd.edu...
Efficient oligonucleotide probe selection for pan-genomic tiling arraysAdam M Phillippy
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
BMC Bioinformatics 10:293. 2009..Prior microarrays have included only a single strain per array or the conserved sequences of gene families. These arrays omit potentially important genes and sequence variants from the pan-genome...
Genome assembly forensics: finding the elusive mis-assemblyAdam M Phillippy
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
Genome Biol 9:R55. 2008..The software described is compatible with common assembly formats and is released, open-source, at http://amos.sourceforge.net...
Insignia: a DNA signature search web server for diagnostic assay developmentAdam M Phillippy
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, USA
Nucleic Acids Res 37:W229-34. 2009..The Insignia website (http://insignia.cbcb.umd.edu) is free and open to all users and there is no login requirement. In addition, the source code for the computational pipeline is freely available...
Hawkeye: an interactive visual analytics tool for genome assembliesMichael C Schatz
Center for Bioinformatics and Computational Biology, Biomolecular Sciences Building, University of Maryland, College Park, Maryland 20742, USA
Genome Biol 8:R34. 2007..Hawkeye is freely available and released as part of the open source AMOS project http://amos.sourceforge.net/hawkeye...
Genome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PXO99ASteven L Salzberg
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
BMC Genomics 9:204. 2008..We report here on the complete genome sequence of strain PXO99A and its comparison to two previously sequenced strains, KACC10331 and MAFF311018, which are highly similar to one another...
Using MUMmer to identify similar regions in large sequence setsArthur L Delcher
The Institute for Genomic Research Rockville, Maryland and Computer Science Department, Loyola College in Maryland, Baltimore, Maryland, USA
Curr Protoc Bioinformatics . 2003..The system is particularly efficient at comparing highly similar sequences, such as alternative versions of fragment assemblies or closely related strains of the same bacterium...
Evolution of genes and genomes on the Drosophila phylogenyAndrew G Clark
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
Nature 450:203-18. 2007..These may prove to underlie differences in the ecology and behaviour of these diverse species...
Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides ethenogenesRekha Seshadri
Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Science 307:105-8. 2005..Genome analysis provides insights into the organism's complex nutrient requirements and suggests that an ancestor was a nitrogen-fixing autotroph...
