KARL PFENNINGER

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Functional complexity of the axonal growth cone: a proteomic analysis
    Adriana Estrada-Bernal
    Department of Pediatrics and Colorado Intellectual and Developmental Disabilities Research Center, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 7:e31858. 2012
  2. pmc Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance
    Lucas J Sosa
    Department of Pediatrics and Colorado Intellectual and Developmental Disabilities Research Center, University of Colorado School of Medicine, Aurora, Colorado, USA
    PLoS ONE 8:e64521. 2013
  3. pmc Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome
    Lucas J Sosa
    3Department of Pediatrics, University of Colorado, Mailbox 8313, 12800 E 19th Ave, Aurora, CO 80045, USA
    FASEB J 28:195-205. 2014
  4. doi request reprint Plasma membrane expansion: a neuron's Herculean task
    Karl H Pfenninger
    Anschutz Medical Campus, Pediatrics and IDDRC, University of Colorado Denver, Aurora, CO 80045, USA
    Nat Rev Neurosci 10:251-61. 2009
  5. ncbi request reprint Functional analysis of SIRPalpha in the growth cone
    Xiaoxin X Wang
    Department of Cell and Developmental Biology, University of Colorado School of Medicine and University of Colorado Cancer Center, Aurora, CO 80010, USA
    J Cell Sci 119:172-83. 2006
  6. pmc Myristoylated, alanine-rich C-kinase substrate phosphorylation regulates growth cone adhesion and pathfinding
    Jesse C Gatlin
    Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Cancer Center, Aurora, CO 80045, USA
    Mol Biol Cell 17:5115-30. 2006
  7. pmc Dynamic adhesions and MARCKS in melanoma cells
    Adriana Estrada-Bernal
    Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Cancer Center, and Colorado Intellectual and Developmental Disabilities Research Center, Aurora, CO 80045, USA
    J Cell Sci 122:2300-10. 2009

Research Grants

  1. Growth Cone Adhesion And Motility
    KARL PFENNINGER; Fiscal Year: 2009
  2. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2002
  3. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2001
  4. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2003
  5. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2004
  6. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2005
  7. Growth Cone Adhesion And Motility
    Karl H Pfenninger; Fiscal Year: 2010

Collaborators

  • Kirk C Hansen
  • Adriana Estrada-Bernal
  • Lucas J Sosa
  • Jesse C Gatlin
  • Staci D Sanford
  • Xiaoxin X Wang
  • Jorge Busciglio
  • Nienke L Postma
  • M Hanna
  • R Guo
  • Jared Bergman
  • John M Kittelson
  • Thomas J Glorioso
  • Glenn C Simon
  • Somkiat Sunpaweravong

Detail Information

Publications7

  1. pmc Functional complexity of the axonal growth cone: a proteomic analysis
    Adriana Estrada-Bernal
    Department of Pediatrics and Colorado Intellectual and Developmental Disabilities Research Center, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 7:e31858. 2012
    ..Our study provides a resource for further research and amplifies the relatively recently developed concept that the axonal growth cone is equipped with proteins capable of performing a highly diverse range of functions...
  2. pmc Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance
    Lucas J Sosa
    Department of Pediatrics and Colorado Intellectual and Developmental Disabilities Research Center, University of Colorado School of Medicine, Aurora, Colorado, USA
    PLoS ONE 8:e64521. 2013
    ..It follows that APP is an independently operating cell adhesion molecule that affects the GC's phenotype on APP-binding matrices including laminin, and that it is likely to affect axon pathfinding in vivo...
  3. pmc Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome
    Lucas J Sosa
    3Department of Pediatrics, University of Colorado, Mailbox 8313, 12800 E 19th Ave, Aurora, CO 80045, USA
    FASEB J 28:195-205. 2014
    ..The results suggest that APP overexpression may perturb axonal pathfinding and circuit formation in developing DS brain...
  4. doi request reprint Plasma membrane expansion: a neuron's Herculean task
    Karl H Pfenninger
    Anschutz Medical Campus, Pediatrics and IDDRC, University of Colorado Denver, Aurora, CO 80045, USA
    Nat Rev Neurosci 10:251-61. 2009
    ..Current knowledge of this process and its implications for neuronal development, function and repair are reviewed...
  5. ncbi request reprint Functional analysis of SIRPalpha in the growth cone
    Xiaoxin X Wang
    Department of Cell and Developmental Biology, University of Colorado School of Medicine and University of Colorado Cancer Center, Aurora, CO 80010, USA
    J Cell Sci 119:172-83. 2006
    ..Thus, the effect of cSIRPalpha on axon growth is dependent upon integrin activation by laminin. These results suggest that SIRPalpha functions in the modulation of axonal growth by ECM molecules, such as laminin...
  6. pmc Myristoylated, alanine-rich C-kinase substrate phosphorylation regulates growth cone adhesion and pathfinding
    Jesse C Gatlin
    Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Cancer Center, Aurora, CO 80045, USA
    Mol Biol Cell 17:5115-30. 2006
    ....
  7. pmc Dynamic adhesions and MARCKS in melanoma cells
    Adriana Estrada-Bernal
    Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Cancer Center, and Colorado Intellectual and Developmental Disabilities Research Center, Aurora, CO 80045, USA
    J Cell Sci 122:2300-10. 2009
    ..Overall, these results begin to define the molecular and functional properties of dynamic close adhesions involved in cell motility...

Research Grants7

  1. Growth Cone Adhesion And Motility
    KARL PFENNINGER; Fiscal Year: 2009
    ..abstract_text> ..
  2. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2002
    ..abstract_text> ..
  3. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2001
    ..abstract_text> ..
  4. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2003
    ..abstract_text> ..
  5. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2004
    ..abstract_text> ..
  6. EICOSANOID IN GROWTH CONE REPELLENT SIGNALING
    KARL PFENNINGER; Fiscal Year: 2005
    ..abstract_text> ..
  7. Growth Cone Adhesion And Motility
    Karl H Pfenninger; Fiscal Year: 2010
    ..abstract_text> ..