Larysa Pevny

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi request reprint The stem-cell menagerie
    Larysa Pevny
    Department of Genetics, Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA
    Trends Neurosci 26:351-9. 2003
  2. ncbi request reprint SOX genes and neural progenitor identity
    Larysa Pevny
    Department of Genetics, Neuroscience Center, University of North Carolina CB 7264, 103 Mason Farm Road, Chapel Hill, North Carolina, NC 27599, USA
    Curr Opin Neurobiol 15:7-13. 2005
  3. ncbi request reprint SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult
    Pam Ellis
    Neuroscience Center, Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA
    Dev Neurosci 26:148-65. 2004
  4. pmc Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium
    Eric S Tucker
    Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, NC 27599, USA
    Development 137:2471-81. 2010
  5. ncbi request reprint SOX2 functions to maintain neural progenitor identity
    Victoria Graham
    Neuroscience Center, Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA
    Neuron 39:749-65. 2003
  6. pmc SOX2 maintains the quiescent progenitor cell state of postnatal retinal Muller glia
    Natalia Surzenko
    UNC Neuroscience Center, Department of Genetics, University of North Carolina, 115 Mason Farm Road, Chapel Hill, NC 27599, USA
    Development 140:1445-56. 2013
  7. pmc Nap1-regulated neuronal cytoskeletal dynamics is essential for the final differentiation of neurons in cerebral cortex
    Yukako Yokota
    UNC Neuroscience Center, Department of Cell and Molecular Physiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Neuron 54:429-45. 2007
  8. pmc Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
    Jeffrey H Fair
    Department of Surgery, University of North Carolina, Chapel Hill, NC 27599, USA
    Proc Natl Acad Sci U S A 102:2958-63. 2005
  9. doi request reprint SOX2 hypomorphism disrupts development of the prechordal floor and optic cup
    Lee Langer
    Department of Genetics, University of North Carolina at Chapel Hill, 115 Mason Farm Rd, CB 7250, Chapel Hill, NC 27599, USA
    Mech Dev 129:1-12. 2012
  10. pmc The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone
    H T Ghashghaei
    University of North Carolina Neuroscience Center and the Department of Cell and Molecular Physiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Proc Natl Acad Sci U S A 103:1930-5. 2006

Collaborators

Detail Information

Publications13

  1. ncbi request reprint The stem-cell menagerie
    Larysa Pevny
    Department of Genetics, Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA
    Trends Neurosci 26:351-9. 2003
    ....
  2. ncbi request reprint SOX genes and neural progenitor identity
    Larysa Pevny
    Department of Genetics, Neuroscience Center, University of North Carolina CB 7264, 103 Mason Farm Road, Chapel Hill, North Carolina, NC 27599, USA
    Curr Opin Neurobiol 15:7-13. 2005
    ....
  3. ncbi request reprint SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult
    Pam Ellis
    Neuroscience Center, Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA
    Dev Neurosci 26:148-65. 2004
    ..These studies demonstrate that SOX2 may meet the requirements of a universal neural stem cell marker and provides a means to identify cells which fulfill the basic criteria of a stem cell: self-renewal and multipotent differentiation...
  4. pmc Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium
    Eric S Tucker
    Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, NC 27599, USA
    Development 137:2471-81. 2010
    ....
  5. ncbi request reprint SOX2 functions to maintain neural progenitor identity
    Victoria Graham
    Neuroscience Center, Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA
    Neuron 39:749-65. 2003
    ..Taken together, these data indicate that SOXB1 signaling is both necessary and sufficient to maintain panneural properties of neural progenitor cells...
  6. pmc SOX2 maintains the quiescent progenitor cell state of postnatal retinal Muller glia
    Natalia Surzenko
    UNC Neuroscience Center, Department of Genetics, University of North Carolina, 115 Mason Farm Road, Chapel Hill, NC 27599, USA
    Development 140:1445-56. 2013
    ..Collectively, these results uncouple the roles of SOX2 and the Notch signaling pathway in the postnatal retina, and uncover a novel role for SOX2 in preventing the depletion of postnatal Müller glia through terminal cell division...
  7. pmc Nap1-regulated neuronal cytoskeletal dynamics is essential for the final differentiation of neurons in cerebral cortex
    Yukako Yokota
    UNC Neuroscience Center, Department of Cell and Molecular Physiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Neuron 54:429-45. 2007
    ..Thus, Nap1 plays an essential role in facilitating neuronal cytoskeletal changes underlying the postmigratory differentiation of cortical neurons, a critical step in functional wiring of the cortex...
  8. pmc Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
    Jeffrey H Fair
    Department of Surgery, University of North Carolina, Chapel Hill, NC 27599, USA
    Proc Natl Acad Sci U S A 102:2958-63. 2005
    ..The PEP engraftment was not associated with detectable cell fusion, and the transplantation was accompanied with only a low incidence of teratoma formation...
  9. doi request reprint SOX2 hypomorphism disrupts development of the prechordal floor and optic cup
    Lee Langer
    Department of Genetics, University of North Carolina at Chapel Hill, 115 Mason Farm Rd, CB 7250, Chapel Hill, NC 27599, USA
    Mech Dev 129:1-12. 2012
    ....
  10. pmc The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone
    H T Ghashghaei
    University of North Carolina Neuroscience Center and the Department of Cell and Molecular Physiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Proc Natl Acad Sci U S A 103:1930-5. 2006
    ..Furthermore, these studies identify NRG2 as a factor capable of promoting SVZ proliferation, leading to the formation of new neurons in vivo...
  11. ncbi request reprint "Runx"ing towards sensory differentiation
    Jian Zhong
    UNC Neuroscience Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Neuron 49:325-7. 2006
    ..These findings emphasize the importance of intrinsic genetic programs in generating the diversity of DRG neurons and specifying the circuits into which they incorporate...
  12. ncbi request reprint Induction of hepatic differentiation in embryonic stem cells by co-culture with embryonic cardiac mesoderm
    Jeffrey H Fair
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Surgery 134:189-96. 2003
    ....
  13. ncbi request reprint Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain
    Christine Y Brazel
    Laboratory of Neurosciences, National Institute on Aging, Baltimore, MD 21224, USA
    Aging Cell 4:197-207. 2005
    ..Thus, we propose that the expression of Sox2 is a unifying characteristic of NSCs in the adult brain, but that not all NSCs maintain the ability to form all neural cell types in vivo...