William A Petri

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi request reprint America in the world: 100 years of tropical medicine and hygiene
    William A Petri
    Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22908 1340, USA
    Am J Trop Med Hyg 71:2-16. 2004
  2. pmc Entamoeba histolytica phagocytosis of human erythrocytes involves PATMK, a member of the transmembrane kinase family
    Douglas R Boettner
    Department of Microbiology, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS Pathog 4:e8. 2008
  3. pmc Characterization of an Entamoeba histolytica high-mobility-group box protein induced during intestinal infection
    Mayuresh M Abhyankar
    Departments of Medicine, University of Virginia, Charlottesville, VA 22908 1340, USA
    Eukaryot Cell 7:1565-72. 2008
  4. ncbi request reprint The mouse model of amebic colitis reveals mouse strain susceptibility to infection and exacerbation of disease by CD4+ T cells
    Eric R Houpt
    Division of Infectious Diseases, Department of Medicine, University of Virginia School of Medicine, 300 Lane Road, Charlottesville, VA 22908, USA
    J Immunol 169:4496-503. 2002
  5. pmc Phospholipid-binding protein EhC2A mediates calcium-dependent translocation of transcription factor URE3-BP to the plasma membrane of Entamoeba histolytica
    Heriberto Moreno
    Division of Infectious Diseases and International Health, University of Virginia, P O Box 801340, Charlottesville, VA 22908, USA
    Eukaryot Cell 9:695-704. 2010
  6. pmc Using differential gene expression to study Entamoeba histolytica pathogenesis
    Carol A Gilchrist
    Division of Infectious Diseases and International Health, Departments of Medicine, Microbiology and Pathology, University of Virginia, PO Box 801340, Charlottesville, VA 22908 1340, USA
    Trends Parasitol 25:124-31. 2009
  7. pmc Identification and gene expression analysis of a large family of transmembrane kinases related to the Gal/GalNAc lectin in Entamoeba histolytica
    David L Beck
    Department of Microbiology, University of Virginia, Charlottesville, VA 22908 1340, USA
    Eukaryot Cell 4:722-32. 2005
  8. ncbi request reprint Entamoeba histolytica: sequence conservation of the Gal/GalNAc lectin from clinical isolates
    David L Beck
    Department of Internal Medicine, University of Virginia, Charlottesville, VA 22908 1340, USA
    Exp Parasitol 101:157-63. 2002
  9. pmc Protection against intestinal amebiasis by a recombinant vaccine is transferable by T cells and mediated by gamma interferon
    Xiaoti Guo
    Division of Infectious Diseases and International Health, Department of Internal Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Infect Immun 77:3909-18. 2009
  10. pmc Comparison of two immunoassays for detection of Entamoeba histolytica
    Sarah Buss
    Department of Microbiology, University of Virginia, Charlottesville, Virginia 22908, USA
    J Clin Microbiol 46:2778-9. 2008

Collaborators

Detail Information

Publications68

  1. ncbi request reprint America in the world: 100 years of tropical medicine and hygiene
    William A Petri
    Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22908 1340, USA
    Am J Trop Med Hyg 71:2-16. 2004
  2. pmc Entamoeba histolytica phagocytosis of human erythrocytes involves PATMK, a member of the transmembrane kinase family
    Douglas R Boettner
    Department of Microbiology, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS Pathog 4:e8. 2008
    ..In conclusion, PATMK was identified as a member of the TMK family that participates in erythrophagocytosis and is uniquely required for intestinal infection...
  3. pmc Characterization of an Entamoeba histolytica high-mobility-group box protein induced during intestinal infection
    Mayuresh M Abhyankar
    Departments of Medicine, University of Virginia, Charlottesville, VA 22908 1340, USA
    Eukaryot Cell 7:1565-72. 2008
    ..We concluded that EhHMGB1 was a bona fide HMGB protein with the capacity to recapitulate part of the modulation of parasite gene expression seen during adaptation to the host intestine...
  4. ncbi request reprint The mouse model of amebic colitis reveals mouse strain susceptibility to infection and exacerbation of disease by CD4+ T cells
    Eric R Houpt
    Division of Infectious Diseases, Department of Medicine, University of Virginia School of Medicine, 300 Lane Road, Charlottesville, VA 22908, USA
    J Immunol 169:4496-503. 2002
    ..This model reveals important immune factors that influence susceptibility to infection and demonstrates for the first time the pathologic contribution of the host immune response in amebiasis...
  5. pmc Phospholipid-binding protein EhC2A mediates calcium-dependent translocation of transcription factor URE3-BP to the plasma membrane of Entamoeba histolytica
    Heriberto Moreno
    Division of Infectious Diseases and International Health, University of Virginia, P O Box 801340, Charlottesville, VA 22908, USA
    Eukaryot Cell 9:695-704. 2010
    ..Based on these results, we propose a model for EhC2A-mediated regulation of the transcriptional activities of URE3-BP via Ca(2+)-dependent anchoring of the transcription factor to the amebic plasma membrane...
  6. pmc Using differential gene expression to study Entamoeba histolytica pathogenesis
    Carol A Gilchrist
    Division of Infectious Diseases and International Health, Departments of Medicine, Microbiology and Pathology, University of Virginia, PO Box 801340, Charlottesville, VA 22908 1340, USA
    Trends Parasitol 25:124-31. 2009
    ..The association and potential contribution of differential gene expression to the life cycle and the virulence of this protozoan parasite of humans are reviewed here...
  7. pmc Identification and gene expression analysis of a large family of transmembrane kinases related to the Gal/GalNAc lectin in Entamoeba histolytica
    David L Beck
    Department of Microbiology, University of Virginia, Charlottesville, VA 22908 1340, USA
    Eukaryot Cell 4:722-32. 2005
    ..The presence of multiple receptor kinases in the plasma membrane offers for the first time a potential explanation of the ability of the parasite to respond to the changing environment of the host...
  8. ncbi request reprint Entamoeba histolytica: sequence conservation of the Gal/GalNAc lectin from clinical isolates
    David L Beck
    Department of Internal Medicine, University of Virginia, Charlottesville, VA 22908 1340, USA
    Exp Parasitol 101:157-63. 2002
    ..histolytica is a clonal population. Sequence conservation of the lectin indicates that immune responses against it should be cross-protective...
  9. pmc Protection against intestinal amebiasis by a recombinant vaccine is transferable by T cells and mediated by gamma interferon
    Xiaoti Guo
    Division of Infectious Diseases and International Health, Department of Internal Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Infect Immun 77:3909-18. 2009
    ..These data demonstrate that CMI is sufficient for vaccine protection from intestinal amebiasis and reveal an important role for IFN-gamma, even in the setting of alum...
  10. pmc Comparison of two immunoassays for detection of Entamoeba histolytica
    Sarah Buss
    Department of Microbiology, University of Virginia, Charlottesville, Virginia 22908, USA
    J Clin Microbiol 46:2778-9. 2008
    ..In this study, we compared the commercially available Ridascreen Entamoeba test (R-Biopharm) and the E. histolytica II test (Techlab), and we found that the E. histolytica II test detects E. histolytica infections more accurately...
  11. ncbi request reprint Histone acetyltransferases and deacetylase in Entamoeba histolytica
    Girija Ramakrishnan
    Department of Medicine, University of Virginia, Charlottesville, VA 22908, USA
    Mol Biochem Parasitol 138:205-16. 2004
    ..histolytica trophozoites. Our results suggest that mechanisms for histone acetylation and deacetylation are operational in E. histolytica...
  12. pmc Association between TNF-alpha and Entamoeba histolytica diarrhea
    KRISTINE M PETERSON
    Division of Infectious Diseases, University of Virginia Health Systems, PO BOX 801337, Building MR4, Room 2115, 409 Lane Road, Charlottesville, VA, USA
    Am J Trop Med Hyg 82:620-5. 2010
    ..histolytica diarrhea compared with convalescence. We conclude that there is an association between higher TNF-alpha production and E. histolytica diarrhea...
  13. ncbi request reprint Therapy of intestinal protozoa
    William A Petri
    University of Virginia Health System, PO Box 801340, MR4 Building, Room 2115, Lane Road, Charlottesville, VA 22908 1340, USA
    Trends Parasitol 19:523-6. 2003
  14. ncbi request reprint Amebic colitis: new insights into pathogenesis and treatment
    Tracy E Bercu
    Division of Infectious Diseases and International Health, University of Virginia Health System, P O Box 801340, Charlottesville, VA 22908, USA
    Curr Gastroenterol Rep 9:429-33. 2007
    ..The disease mechanisms, clinical findings, therapeutic strategies, and important developments regarding amebiasis are discussed here...
  15. pmc Evaluation of Entamoeba histolytica antigen and antibody point-of-care tests for the rapid diagnosis of amebiasis
    Megan Leo
    University of Virginia, P O Box 801340, Charlottesville, VA 22908 1340, USA
    J Clin Microbiol 44:4569-71. 2006
    ....
  16. ncbi request reprint Vaccine prospects for amebiasis
    Omer A Chaudhry
    Division of Infectious Diseases and International Medicine, Department of Internal Medicine, University of Virginia Health System, Charlottesville, VA 22908 1340, USA
    Expert Rev Vaccines 4:657-68. 2005
    ..histolytica protein, cysteine proteinases, lipophosphoglycans, amebapores and the 29-kDa protein...
  17. ncbi request reprint Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome
    Carol A Gilchrist
    Department of Internal Medicine, University of Virginia, Charlottesville, VA 22908 1340, USA
    Mol Biochem Parasitol 147:163-76. 2006
    ....
  18. ncbi request reprint Cognitive effects of diarrhea, malnutrition, and Entamoeba histolytica infection on school age children in Dhaka, Bangladesh
    Jessica L Tarleton
    Division of Infectious Diseases and International Health, University of Virginia, Charlottesville Virginia, USA
    Am J Trop Med Hyg 74:475-81. 2006
    ..histolytica infection, was associated with a lower level of cognitive functioning. This suggested that intervention during school age years may be able to mitigate the cognitive deficiencies associated with malnutrition...
  19. ncbi request reprint Prevention of intestinal amebiasis by vaccination with the Entamoeba histolytica Gal/GalNac lectin
    Eric Houpt
    Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia, 300 Lane Rd, PO Box 801340, MR4 Building Room 2115, Charlottesville, VA 22908, USA
    Vaccine 22:611-7. 2004
    ..These results show for the first time that immunization with the Gal/GalNAc lectin can prevent intestinal amebiasis in mice and suggest a protective role for fecal anti-lectin IgA in vivo...
  20. pmc Molecular epidemiology of amebiasis
    Ibne Karim M Ali
    Division of Infectious Diseases and International Health, University of Virginia Health System, MR4 Building Room 2115, Lane Road, Charlottesville, VA 22908, USA
    Infect Genet Evol 8:698-707. 2008
    ..histolytica remain largely unknown. We anticipate that the recently completed E. histolytica genome sequence and new molecular techniques will rapidly advance our understanding of the epidemiology and pathogenicity of amebiasis...
  21. pmc Members of the Entamoeba histolytica transmembrane kinase family play non-redundant roles in growth and phagocytosis
    Sarah N Buss
    Department of Microbiology, University of Virginia, Charlottesville, VA 22908 1340, USA
    Int J Parasitol 40:833-43. 2010
    ..histolytica Gal/GalNAc lectin. Overall, our data indicates that multiple members of the novel E. histolytica TMK family are utilised for non-redundant functions by the parasite...
  22. ncbi request reprint The bittersweet interface of parasite and host: lectin-carbohydrate interactions during human invasion by the parasite Entamoeba histolytica
    William A Petri
    Division of Infectious Diseases, University of Virginia, MR4 Bldg Room 2115, Lane Road, Charlottesville 22908 1340, USA
    Annu Rev Microbiol 56:39-64. 2002
    ..The structure and function of the lectin that controls these divergent cell biologic processes are the subject of this review...
  23. ncbi request reprint Pathogenesis of amebiasis
    William A Petri
    Division of Infectious Diseases, Room 2115, MR4 Building, Lane Road, PO Box 801340, University of Virginia Health System, Charlottesville, Virginia 22908 1340, USA
    Curr Opin Microbiol 5:443-7. 2002
    ..The mechanism of transcriptional control via histone modifications and sequence-specific DNA-binding proteins are to be delineated. Advances in cell biology are providing new insights into invasion through the intestinal epithelium...
  24. ncbi request reprint Adherence-blocking vaccine for amebiasis
    William A Petri
    Division of Infectious Diseases and International Health, University of Virginia Health System, Charlottesville, Virginia 22908 1340, USA
    Arch Med Res 37:288-91. 2006
    ..Accomplishing this will enable testing of the ability of LecA immunizations to protect from amebic colitis in humans...
  25. doi request reprint Association of malnutrition with amebiasis
    William A Petri
    Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA
    Nutr Rev 67:S207-15. 2009
    ..Future efforts aimed at understanding the mechanisms of these effects are described...
  26. pmc Apoptotic killing and phagocytosis of host cells by the parasite Entamoeba histolytica
    Christopher D Huston
    Department of Medicine, University of Virginia Health System, Charlottesville 22908
    Infect Immun 71:964-72. 2003
    ..003). By analogy with phagocytic clearance during apoptosis in metazoans, amebic apoptotic host cell killing followed by phagocytosis may limit inflammation and enable amebae to evade the host immune response...
  27. ncbi request reprint Can a proteomics strategy be used to identify the anti-malarial activity of chloroquine?
    William A Petri
    Division of Infectious Diseases, University of Virginia School of Medicine, PO Box 801340, MR4 Building Room 2115, Charlottesville 22908 1340, USA
    Trends Pharmacol Sci 24:210-2; discussion 212-3. 2003
    ....
  28. pmc Targets of the Entamoeba histolytica transcription factor URE3-BP
    Carol A Gilchrist
    Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS Negl Trop Dis 2:e282. 2008
    ..histolytica in response to a calcium signal. Induction of URE3-BP leads to an increase in tranwell migration, suggesting a possible role in the regulation of cellular motility...
  29. pmc Short hairpin RNA-mediated knockdown of protein expression in Entamoeba histolytica
    Alicia S Linford
    Department of Microbiology, University of Virginia, Charlottesville, Virginia, USA
    BMC Microbiol 9:38. 2009
    ..We chose to test the use of RNA interference to knock down gene expression in Entamoeba histolytica...
  30. ncbi request reprint Context-dependent roles of the Entamoeba histolytica core promoter element GAAC in transcriptional activation and protein complex assembly
    Upinder Singh
    Department of Medicine, University of Virginia, Charlottesville, VA 22908, USA
    Mol Biochem Parasitol 120:107-16. 2002
    ..The differing effect on transcription initiation in the hgl5 and fdx genes upon mutation of the GAAC element suggests a context-dependence of the GAAC-binding protein in gene expression...
  31. ncbi request reprint Roles for the galactose-/N-acetylgalactosamine-binding lectin of Entamoeba in parasite virulence and differentiation
    Jesse R Frederick
    Division of Infectious Diseases, University of Virginia Health System, MR4 Building, Room 2115, Charlottesville, VA 22908 1340, USA
    Glycobiology 15:53R-59R. 2005
    ..The lectin-glycan interactions that initiate these diverse processes are discussed with emphasis on comparing the binding of host ligands and the interactions involved in encystation...
  32. ncbi request reprint Opportunities and obstacles in developing a vaccine for Entamoeba histolytica
    Vanessa C Miller-Sims
    Department of Internal Medicine, University of Virginia, Charlottesville, VA 22908, USA
    Curr Opin Immunol 14:549-52. 2002
    ..histolytica Gal/GalNAc lectin antibodies, suggesting that a vaccine is an achievable goal. However, garnering resources for vaccine development is a challenge when the vaccine is targeted to poor people living in developing countries...
  33. pmc Crosstalk at the initial encounter: interplay between host defense and ameba survival strategies
    Xiaoti Guo
    Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22908 1340, USA
    Curr Opin Immunol 19:376-84. 2007
    ..Understanding this crosstalk is crucial for the effective design and implementation of new vaccines and drugs for this leading parasitic disease...
  34. pmc Entamoeba histolytica and Entamoeba dispar utilize externalized phosphatidylserine for recognition and phagocytosis of erythrocytes
    Douglas R Boettner
    Division of Infectious Diseases and International Health, P O Box 801340, Rm 2115, MR4 Building, University of Virginia Health System, Charlottesville, VA 22908 1340, USA
    Infect Immun 73:3422-30. 2005
    ..These findings establish phosphatidylserine involvement in erythrophagocytosis by amebae and suggest the existence of a PS receptor on the surfaces of both E. histolytica and E. dispar...
  35. pmc Intestinal invasion by Entamoeba histolytica
    Shahram Solaymani-Mohammadi
    Department of Medicine Infectious Disease, University of Virginia, Charlottesville, Virginia, USA
    Subcell Biochem 47:221-32. 2008
  36. pmc Giardia intestinalis assemblages A and B infections in Nepal
    Anjana Singh
    Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA
    Am J Trop Med Hyg 81:538-9. 2009
    ..Genotyping of the Giardia PCR product by restriction fragment length polymorphism indicated that 74% (26 of 35) were assemblage B, 20% (7 of 35) were assemblage A, and 6% (2 of 35) were mixed assemblages...
  37. pmc Evaluation of a screening test for detection of giardia and cryptosporidium parasites
    Sojin Youn
    University of Virginia School of Medicine, Charlottesville, VA 22908 1340, USA
    J Clin Microbiol 47:451-2. 2009
    ..Using the results of the Giardia II test and Cryptosporidium II test as gold standards, it was 98.4% sensitive and 100% specific and had positive and negative predictive values of 98.7% and 99.3%...
  38. ncbi request reprint Calcium modulates promoter occupancy by the Entamoeba histolytica Ca2+-binding transcription factor URE3-BP
    Carol A Gilchrist
    Department of Internal Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    J Biol Chem 278:4646-53. 2003
    ..Modulation of URE3-BP by calcium may represent an important mechanism of control of gene expression in E. histolytica...
  39. pmc Development of the Gateway system for cloning and expressing genes in Entamoeba histolytica
    Mayuresh M Abhyankar
    Department of Medicine, University of Virginia, Charlottesville, VA, USA
    Parasitol Int 58:95-7. 2009
    ..This expression vector with the Gateway((R)) system should facilitate investigation into the functions of novel proteins in E. histolytica...
  40. pmc Enteric infections, diarrhea, and their impact on function and development
    William A Petri
    Center for Global Health, Division of Infectious Diseases and International Health, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    J Clin Invest 118:1277-90. 2008
    ..We also discuss specific implications for novel approaches to interventions that are now opened by our rapidly growing molecular understanding...
  41. ncbi request reprint In vitro and in vivo interaction of Entamoeba histolytica Gal/GalNAc lectin with various target cells: an immunocytochemical analysis
    Judith Pacheco
    Department of Experimental Pathology, Center for Research and Advanced Studies, National Polytechnic Institute, CINVESTAV IPN, Av IPN 2508, Col San Pedro Zacatenco, Mexico, D F 07360, Mexico
    Parasitol Int 53:35-47. 2004
    ..The contribution of lectin transfer to host cells in adherence and cell injury remains to be determined...
  42. ncbi request reprint Influence of human leukocyte antigen class II alleles on susceptibility to Entamoeba histolytica infection in Bangladeshi children
    Priya Duggal
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
    J Infect Dis 189:520-6. 2004
    ..To test this hypothesis, we compared the genotype frequencies of human leukocyte antigen (HLA) class II alleles in a cohort of Bangladeshi children intensively monitored for E. histolytica infection for a 3-year period...
  43. ncbi request reprint Meeting report: EMBO workshop "Pathogenesis of amoebiasis: from genomics to disease", Institut Pasteur, Paris, May 19-22, 2003
    Egbert Tannich
    Protist 154:293-8. 2003
  44. ncbi request reprint Epidemiologic and clinical characteristics of acute diarrhea with emphasis on Entamoeba histolytica infections in preschool children in an urban slum of Dhaka, Bangladesh
    Rashidul Haque
    Centre for Health and Population Research, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Am J Trop Med Hyg 69:398-405. 2003
    ..Understanding the etiology, frequency, and consequences of acute diarrhea in children from a developing country should aid in the design of interventions to improve child health...
  45. pmc VH3 gene usage in neutralizing human antibodies specific for the Entamoeba histolytica Gal/GalNAc lectin heavy subunit
    Hiroshi Tachibana
    Department of Infectious Diseases, Tokai University School of Medicine, Isehara, Kanagawa 259 1193, Japan
    Infect Immun 71:4313-9. 2003
    ..These results demonstrate the utility of a combinatorial human immunoglobulin gene library for identifying and characterizing neutralizing antibodies from humans with amebiasis...
  46. pmc Entamoeba moshkovskii infections in children, Bangladesh
    Ibne Karim M Ali
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
    Emerg Infect Dis 9:580-4. 2003
    ..dispar. The high association of E. moshkovskii with E. histolytica and E. dispar may have obscured its identification in previous studies. The high prevalence found in this study suggests that humans may be a true host for this amoeba...
  47. ncbi request reprint Amebiasis
    Rashidul Haque
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    N Engl J Med 348:1565-73. 2003
  48. ncbi request reprint Outbreak of amebiasis in Tbilisi, Republic of Georgia, 1998
    Rachel S Barwick
    Epidemic Intelligence Service, Epidemiology Program Office, and Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Am J Trop Med Hyg 67:623-31. 2002
    ..The data support the hypothesis that drinking water was the source of infection, either because of inadequate municipal water treatment or contamination of municipal water in the distribution system...
  49. ncbi request reprint Innate and acquired resistance to amebiasis in bangladeshi children
    Rashidul Haque
    Centre for Health and Population Research, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    J Infect Dis 186:547-52. 2002
    ..This was associated with an 86% reduction in new infection over 1 year. Amebiasis is a common and potentially serious infection in children from Dhaka, and both innate and acquired immune responses limit infection...
  50. ncbi request reprint Examining entamoeba
    Sudha Bhattacharya
    Jawaharlal Nehru University, New Mehrauli Road, New Delhi 110067, India
    Trends Parasitol 18:196-7. 2002
    ..A conference on Amebiasis and the Biology of Entamoeba histolytica was held in Agra, India, from 11 to14 February 2002...
  51. pmc Entamoeba histolytica infection in children and protection from subsequent amebiasis
    Rashidul Haque
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Infect Immun 74:904-9. 2006
    ..The challenge of producing an effective vaccine will be to improve upon naturally acquired immunity, which does not provide absolute protection from reinfection...
  52. pmc Association between Cryptosporidium infection and human leukocyte antigen class I and class II alleles
    Beth D Kirkpatrick
    University of Vermont College of Medicine, Unit of Infectious Diseases, Burlington, VT 05405, USA
    J Infect Dis 197:474-8. 2008
    ..Cryptosporidium species are a common cause of diarrhea, which can be severe and protracted in young children and immunocompromised individuals...
  53. pmc Expression and function of a family of transmembrane kinases from the protozoan parasite Entamoeba histolytica
    Alka Mehra
    School of Life Sciences, Lab No 117, Jawaharlal Nehru University, New Delhi 110067, India
    Infect Immun 74:5341-51. 2006
    ..Inducible expression of the truncated TMK resulted in a decrease in cellular proliferation and an increase in sensitivity to serum starvation. Our data indicate that the B1.I class of TMKs is involved in parasite proliferation...
  54. pmc Comparison of a stool antigen detection kit and PCR for diagnosis of Entamoeba histolytica and Entamoeba dispar infections in asymptomatic cyst passers in Iran
    Shahram Solaymani-Mohammadi
    Division of Intestinal and Genetal Protozoal Diseases, Department of Medical Parasitology and Mycology, School of Public Health and Institute of Public Health Research, Tehran Universoty of Medical Sciences, 14155 Tehran 6446, Iran
    J Clin Microbiol 44:2258-61. 2006
    ..histolytica II stool antigen kit and those from nested PCR. We concluded that E. dispar is much more common in asymptomatic cyst passers in Iran and that antigen detection and PCR are comparable diagnostic modalities...
  55. pmc Evidence for a link between parasite genotype and outcome of infection with Entamoeba histolytica
    Ibne Karim M Ali
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, Great Britain
    J Clin Microbiol 45:285-9. 2007
    ..histolytica. The markers themselves do not indicate the nature of the underlying genetic differences, but they may be linked to loci that do have an impact on the outcome of infection...
  56. ncbi request reprint Correlation of interferon-gamma production by peripheral blood mononuclear cells with childhood malnutrition and susceptibility to amebiasis
    Rashidul Haque
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Am J Trop Med Hyg 76:340-4. 2007
    ..49, P = 0.07). We conclude that production of IFN-gamma is linked to nutritional status and predicts future susceptibility to symptomatic amebiasis...
  57. ncbi request reprint Entamoeba histolytica-associated diarrheal illness is negatively associated with the growth of preschool children: evidence from a prospective study
    Dinesh Mondal
    International Centre for Diarrhoeal Disease Research, Bangladesh, G P O Box 128, Dhaka 1000, Bangladesh
    Trans R Soc Trop Med Hyg 100:1032-8. 2006
    ..01-8.52, P=0.047) more likely to be malnourished and 4.69 times (95% CI 1.55-14.18, P=0.006) more prone to be stunted. Entamoeba histolytica-associated diarrheal illness was negatively associated with the growth of preschool children...
  58. ncbi request reprint Kinetics and strain variation of phagosome proteins of Entamoeba histolytica by proteomic analysis
    Mami Okada
    Department of Parasitology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Mol Biochem Parasitol 145:171-83. 2006
    ..These data should provide significant insights into molecular characterization of phagosome biogenesis, and help to elucidate the pathogenesis of this important infection...
  59. ncbi request reprint Entamoeba histolytica: the serine-rich gene polymorphism-based genetic variability of clinical isolates from Georgia
    Sophia Simonishvili
    National Center for Disease Control and Medical Statistics of Georgia, 9 Asatiani Street, Tbilisi 380077, Georgia
    Exp Parasitol 110:313-7. 2005
    ..histolytica, thus preventing an association of a single genotype with hepatic disease, but supporting the previous finding of extensive genetic diversity among E. histolytica isolates from the same geographic origin...
  60. pmc Real-time-PCR assay for diagnosis of Entamoeba histolytica infection
    Shantanu Roy
    International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    J Clin Microbiol 43:2168-72. 2005
    ..In conclusion, all three methods for the detection of E. histolytica were highly specific, with real-time PCR being the most sensitive...
  61. pmc Proteomic analysis of phagocytosis in the enteric protozoan parasite Entamoeba histolytica
    Mami Okada
    Department of Parasitology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Eukaryot Cell 4:827-31. 2005
    ..Phagosome localization of representative proteins was verified by immunofluorescence assay. This study should provide a basis for molecular identification and characterization of phagosome biogenesis...
  62. ncbi request reprint Comparison of two methods (microscopy and enzyme-linked immunosorbent assay) for the diagnosis of amebiasis
    Mehmet Tanyuksel
    Division of Medical Parasitology, Department of Microbiology and Clinical Microbiology, Gulhane Military Medical Academy, Etlik 06018, Ankara, Turkey
    Exp Parasitol 110:322-6. 2005
    ..3%) Endolimax nana, 9 (2.3%) Dientamoeba fragilis, and 8 (2.1%) had Ascaris lumbricoides. We concluded that E. histolytica infection was found in 13% of the patients presenting with diarrhea in Van and Sanliurfa Turkey...
  63. ncbi request reprint Entamoeba histolytica encephalitis diagnosed by PCR of cerebrospinal fluid
    Shahram Solaymani-Mohammadi
    Division of Intestinal and Genital Protozoal Diseases, Department of Medical Parasitology and Mycology, School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, PO Box 14155, Tehran 6446, Iran
    Trans R Soc Trop Med Hyg 101:311-3. 2007
    ..The patient was treated successfully with metronidazole. PCR is an increasingly useful tool for the diagnosis of central nervous system infection and can provide rapid diagnosis...
  64. pmc Laboratory diagnosis of amebiasis
    Mehmet Tanyuksel
    Department of Microbiology and Clinical Microbiology, Gulhane Military Medical Academy, Etlik, Ankara 06018, Turkey
    Clin Microbiol Rev 16:713-29. 2003
    ..histolytica. All the current tests suffer from the fact that the antigens detected are denatured by fixation of the stool specimen, limiting testing to fresh or frozen samples...
  65. ncbi request reprint Diagnosis of amebiasis in Bangladesh
    Rashidul Haque
    International Centre for Diarrheal Disease Research ICDDR, B, Dhaka, Bangladesh
    Arch Med Res 37:273-6. 2006
    ..histolytica was excellent. TechLab's E. histolytica- specific antigen detection test was both rapid and simple to perform, making it appropriate for use in the developing world, where amebiasis is most prevalent...
  66. ncbi request reprint Multiplex real-time PCR assay for detection of Entamoeba histolytica, Giardia intestinalis, and Cryptosporidium spp
    Rashidul Haque
    International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh
    Am J Trop Med Hyg 76:713-7. 2007
    ....
  67. ncbi request reprint Two cases of rarely recognized infection with Entamoeba moshkovskii
    Mehmet Tanyuksel
    Division of Medical Parasitology, Gulhane Military Medical Academy, Etlik, Ankara, Turkey
    Am J Trop Med Hyg 76:723-4. 2007
    ..histolytica and E. dispar by a nested polymerase chain reaction and restriction fragment length polymorphism analysis of the small subunit ribosomal DNA gene...
  68. ncbi request reprint The genome of the protist parasite Entamoeba histolytica
    Brendan Loftus
    TIGR, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
    Nature 433:865-8. 2005
    ..Analysis of the genome provides new insights into the workings and genome evolution of a major human pathogen...